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== Brendan Innes ==
Email: <<MailTo(brendan DOT innes AT mail DOT utoronto DOT ca)>> 

I am a PhD candidate in Molecular Genetics who started in the Bader lab in May, 2016.  I am very excited about the possibilities offered by high-throughput single-cell RNA-seq, especially to investigate intercellular signalling in complex tissues.

== High-thoughput single-cell RNAseq analysis pipeline ==
I've built a simple pipeline and visualization tool to help collaborators go from raw gene expression counts per cell to exploring annotated cell-type specific gene expression data in a quick and reproducible way.  Below is a quick video showing the sort of data one can get from this pipeline.  If you're interested in applying the pipeline to your count-based single-cell data, please get in touch!

{{attachment:scRNAseqViz.mp4||height=543, width=800}}

=== Education ===
MSc in Biochemistry at the University of Western Ontario, supervised by Dr. David Litchfield

BMSc in Cell Biology and Biochemistry at the University of Western Ontario

=== Teaching Experience ===
TA for MBP1010H - Quantitative Biology and Statistical Methods

=== Publications ===
'''Innes BT''', Sowole MA, Gyenis L, Dubinsky M, Konermann L, Brandl CJ, Litchfield DW, Shilton BH. Peroxide-Mediated Oxidation and Inhibition of the Peptidyl-Prolyl Isomerase Pin1.  Biochim Biophys Acta. 1852(5):905-12, 2015. doi:10.1016/jbbadis.2014.12.025 http://www.ncbi.nlm.nih.gov/pubmed/25595659

Sowole MA, '''Innes BT''', Amunugama M, Brandl CJ, Shilton BH, Litchfield DW, Konermann L.  Noncovalent binding of a cyclic peptide inhibitor to the peptidyl-prolyl isomerase Pin1 explored by hydrogen exchange mass spectrometry.  Can J Chem. July 2014. doi:10.1139/cjc-2014-0230

'''Innes BT''', Bailey ML, Brandl CJ, Shilton BH, Litchfield DW.  Non-catalytic participation of the Pin1 peptidyl-prolyl isomerase domain in target binding.  Front. Physiol. 4:18, 2013. doi:10.3389/fphys.2013.00018.  http://www.ncbi.nlm.nih.gov/pubmed/23407864

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