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| = Bader Computational Pathway Biology Lab = | = Bader Computational Cellular Network Biology Research Lab = |
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| '''Research:'''[[BR]] We study the organization and evolution of biological systems using computational biology and bioinformatics techniques. We seek to accurately predict links, such as specific molecular interactions, in eukaryotic cell signaling systems using comprehensive genomics data like genome sequence and transcript profiles. We are interested to find how these links are rewired by mutations to cause an abnormal phenotype or disease. This work is supported through the development of open-source biological pathway and network databases and visualization and analysis software. |
We study the organization and evolution of biological systems using computational biology and bioinformatics techniques. We seek to accurately predict links, such as specific molecular interactions, in eukaryotic cell signaling systems using comprehensive genomics data like genome sequence and transcript profiles. We are interested to find how these links are rewired by mutations to cause disease. This work is supported through the development of open-source biological pathway and network databases and visualization and analysis software. |
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[:ResearchNonExpert:Non-expert explanation] |
Bader Computational Cellular Network Biology Research Lab
We study the organization and evolution of biological systems using computational biology and bioinformatics techniques. We seek to accurately predict links, such as specific molecular interactions, in eukaryotic cell signaling systems using comprehensive genomics data like genome sequence and transcript profiles. We are interested to find how these links are rewired by mutations to cause disease. This work is supported through the development of open-source biological pathway and network databases and visualization and analysis software.
- Predicting biologically relevant protein interactions
- Analyzing molecular profiles in the context of pathways to find active processes
- Pathway and network databases and analysis tools
[:ResearchNonExpert:Non-expert explanation]
Affiliations:BR [http://tdccbr.med.utoronto.ca Terrence Donnelly Centre for Cellular and Biomolecular Research]BR [http://www.utoronto.ca/ University of Toronto]BR [http://www.utoronto.ca/bandb/ Banting and Best Deparment of Medical Research]BR [http://www.mshri.on.ca/ Samuel Lunenfeld Research Institute] at [http://www.mtsinai.on.ca/ Mount Sinai Hospital]
Where we are:BR 160 College Street, Room 602BR University of TorontoBR Terrence Donnelly Centre for Cellular and Biomolecular ResearchBR Toronto, OntarioBR Canada, M5S 3E1
[http://maps.google.com/maps?f=q&hl=en&q=160+College+St,+Toronto+ON&om=1 Map]
Contact:BR Phone: 416-978-3935BR Fax: 416-978-8287BR gary.bader *a-t* utoronto.caBR Also available by Skype (preferred), iChat, AIM