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| * ''Human Neuropsychiatric'' * ''Human Neurodevelopmental and Intellectual Disability'' * ''Human Other Neurological'' * ''Mouse Neurological Phenotype converted to Human'' * ''Human Specific Brain Expression'' |
== Phenotypes and Expression Specificity == '''Last update: May 2011'''<<BR>> Text files * [[attachment:Neuro_ExpHsBr.txt|ExpHsBr: Human Brain-Specific Expression]] * [[attachment:Neuro_PhMmAll.txt|PhMmAll: Mouse Neurological Phenotypes converted to Human]] * [[attachment:Neuro_PhHsPsy.txt|PhHsPsy: Human Neuropsychiatric Disorders]] * [[attachment:Neuro_PhHsDev.txt|PhHsDev: Human Neurodevelopmental Disorders and Intellectual Disability]] * [[attachment:Neuro_PhHsMsc.txt|PhHsMsc: Human Other Neurological Disorders]] R Workspace * [[attachment:coreNeuroLists.RData|All gene-sets Rws]] |
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| Details * ID: human EntrezGene * Description * |
'''Details''' * __ID System__: human Entrez-Gene * __Documentation__ * [[attachment:Documentation_v01.pdf|PDF]] * [[attachment:Documentation_v01.pptx|pptx]] * __Notes on use__ * All gene-sets have good quality with respect to enrichment in neuropsychological functions and phenotypes * ''!ExpHsBr'' and ''!PhMmAll'' are the ones I found of higher quality when overlapping with my autism gene-set analysis results * ''!PhHsPsy'' probably includes several genes from candidate gene studies, but is otherwise of good quality * The distinction between ''!PhHsPsy'' and ''!PhHsDev'' is a bit loose, these two gene-sets could be collapsed * ''!PhHsMsc'' is quite heterogeneous, and its neurovascular and neurodegenerative auto-immune components are probably source of bad candidates for researchers working on autism, schizophrenia or ADHD * ''!PhMmAll'' is not completely unbiased, as investigators will make KO mouse models for genes of interest * ''!ExpHsBr'' may be partially biased towards well characterized genes |
Neurobiological Gene-sets
Phenotypes and Expression Specificity
Last update: May 2011
Text files
R Workspace
Details
ID System: human Entrez-Gene
Documentation
Notes on use
- All gene-sets have good quality with respect to enrichment in neuropsychological functions and phenotypes
ExpHsBr and PhMmAll are the ones I found of higher quality when overlapping with my autism gene-set analysis results
PhHsPsy probably includes several genes from candidate gene studies, but is otherwise of good quality
The distinction between PhHsPsy and PhHsDev is a bit loose, these two gene-sets could be collapsed
PhHsMsc is quite heterogeneous, and its neurovascular and neurodegenerative auto-immune components are probably source of bad candidates for researchers working on autism, schizophrenia or ADHD
PhMmAll is not completely unbiased, as investigators will make KO mouse models for genes of interest
ExpHsBr may be partially biased towards well characterized genes