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* [[attachment:Neuro_ExpHsBr.txt|'''ExpHsBr: Human Specific Brain Expression''']] * [[attachment:Neuro_PhMmAll.txt|'''PhMmAll: Mouse Neurological Phenotype converted to Human''']] * [[attachment:Neuro_PhHsPsy.txt|'''PhHsPsy: Human Neuropsychiatric''']] * [[attachment:Neuro_PhHsDev.txt|'''PhHsDev: Human Neurodevelopmental and Intellectual Disability''']] * [[attachment:Neuro_PhHsMsc.txt|'''PhHsMsc: Human Other Neurological''']] |
* [[attachment:Neuro_ExpHsBr.txt|ExpHsBr: Human Specific Brain Expression]] * [[attachment:Neuro_PhMmAll.txt|PhMmAll: Mouse Neurological Phenotype converted to Human]] * [[attachment:Neuro_PhHsPsy.txt|PhHsPsy: Human Neuropsychiatric]] * [[attachment:Neuro_PhHsDev.txt|PhHsDev: Human Neurodevelopmental and Intellectual Disability]] * [[attachment:Neuro_PhHsMsc.txt|PhHsMsc: Human Other Neurological]] |
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* ID: human EntrezGene | * ID: human Entrez-Gene |
Neurobiological Gene-sets
Phenotypes and Expression Specificity
Details
- ID: human Entrez-Gene
- [[|Documentation]]
- Notes on use
- All gene-sets have good quality with respect to enrichment in neuropsychological functions and phenotypes
ExpHsBr and PhMmAll are the ones I found of higher quality when overlapping with my autism gene-set analysis results
PhHsPsy probably includes several genes from candidate gene studies, but is otherwise of good quality
The distinction between PhHsPsy and PhHsDev is a bit loose, these two gene-sets could be collapsed
PhMmAll is not completely unbiased, as investigators will make KO mouse models for genes of interest
ExpHsBr may be partially biased towards well characterized genes