Attachment '12hr_DAVID_output.txt'
Download 1 Category Term Count % PValue Genes List Total Pop Hits Pop Total Fold Enrichment Bonferroni Benjamini FDR
2 GOTERM_CC_FAT GO:0031974~membrane-enclosed lumen 95 1.838591058641378 5.210169741980237E-8 FOSL2, UTP18, LYAR, SNRPD3, ARNT2, PDLIM3, UTP15, CCT2, MCM10, WDR74, WDR75, MAK16, PTGES, NARS2, MRPL36, DHX33, DDX21, CAT, CIRH1A, TSEN2, MYB, MYC, HMGCL, CDC7, EXOSC9, MRPL3, RBL2, SSBP1, RAN, EXOSC2, TLE1, MCM2, NCL, PRPF4, C10ORF2, ORC1L, MRTO4, MCM6, NRIP1, NOC2L, CD3EAP, TNS3, RCL1, PA2G4, PPM1E, NAV2, PPM1K, CFL2, IGF2R, FDX1L, ABAT, PMPCB, DSCC1, CLN6, MRPS17, MRPS12, YPEL2, FKBP4, YPEL3, NOC3L, UTP6, PNPT1, BOP1, NR3C1, MYBL1, POLR2D, PPAN, RPA2, KIAA0020, NUMA1, CACYBP, MRPL16, WDR12, NAT10, GEMIN4, OLFM1, GEMIN5, HSPA9, POLR3H, POLR3K, TBX2, PNO1, ILF3, APPL2, FOXP1, PWP2, PPIF, NOLC1, SDF2L1, POLDIP2, ZNF259, RRS1, WDR3, NLN, UTP20 355 1832 11759 1.7176717510301986 1.6724505445320226E-5 1.6724505445320226E-5 7.034155971030742E-5
3 GOTERM_CC_FAT GO:0005730~nucleolus 47 0.909618734275208 2.0945325866842517E-7 FOSL2, UTP18, FKBP4, LYAR, YPEL2, SNRPD3, YPEL3, UTP6, NOC3L, PDLIM3, UTP15, CCT2, MYBL1, NR3C1, BOP1, WDR74, PPAN, KIAA0020, WDR75, MAK16, WDR12, DHX33, DDX21, NAT10, CIRH1A, TSEN2, GEMIN4, EXOSC9, PNO1, EXOSC2, ILF3, NCL, FOXP1, PWP2, MRTO4, NOC2L, CD3EAP, RCL1, TNS3, PA2G4, PPM1E, NOLC1, NAV2, ZNF259, RRS1, WDR3, UTP20 355 683 11759 2.2793929020683397 6.723224287163987E-5 3.361668647661187E-5 2.8277877962556985E-4
4 GOTERM_CC_FAT GO:0070013~intracellular organelle lumen 89 1.7224695180956067 4.733174281845556E-7 FOSL2, UTP18, LYAR, SNRPD3, ARNT2, PDLIM3, UTP15, CCT2, MCM10, WDR74, WDR75, MAK16, NARS2, MRPL36, DHX33, DDX21, CIRH1A, TSEN2, MYB, MYC, HMGCL, CDC7, EXOSC9, MRPL3, RBL2, SSBP1, RAN, EXOSC2, TLE1, MCM2, NCL, PRPF4, C10ORF2, ORC1L, MRTO4, MCM6, NRIP1, NOC2L, CD3EAP, TNS3, RCL1, PA2G4, PPM1E, NAV2, PPM1K, CFL2, FDX1L, ABAT, PMPCB, DSCC1, CLN6, MRPS17, MRPS12, YPEL2, FKBP4, YPEL3, NOC3L, UTP6, BOP1, NR3C1, MYBL1, POLR2D, PPAN, RPA2, KIAA0020, NUMA1, MRPL16, WDR12, NAT10, GEMIN4, OLFM1, GEMIN5, HSPA9, POLR3H, POLR3K, TBX2, PNO1, ILF3, APPL2, FOXP1, PWP2, PPIF, NOLC1, SDF2L1, POLDIP2, ZNF259, RRS1, WDR3, UTP20 355 1756 11759 1.6788331354871826 1.5192338886271806E-4 5.064369436136307E-5 6.390156201963038E-4
5 GOTERM_CC_FAT GO:0043233~organelle lumen 89 1.7224695180956067 1.2919866715260724E-6 FOSL2, UTP18, LYAR, SNRPD3, ARNT2, PDLIM3, UTP15, CCT2, MCM10, WDR74, WDR75, MAK16, NARS2, MRPL36, DHX33, DDX21, CIRH1A, TSEN2, MYB, MYC, HMGCL, CDC7, EXOSC9, MRPL3, RBL2, SSBP1, RAN, EXOSC2, TLE1, MCM2, NCL, PRPF4, C10ORF2, ORC1L, MRTO4, MCM6, NRIP1, NOC2L, CD3EAP, TNS3, RCL1, PA2G4, PPM1E, NAV2, PPM1K, CFL2, FDX1L, ABAT, PMPCB, DSCC1, CLN6, MRPS17, MRPS12, YPEL2, FKBP4, YPEL3, NOC3L, UTP6, BOP1, NR3C1, MYBL1, POLR2D, PPAN, RPA2, KIAA0020, NUMA1, MRPL16, WDR12, NAT10, GEMIN4, OLFM1, GEMIN5, HSPA9, POLR3H, POLR3K, TBX2, PNO1, ILF3, APPL2, FOXP1, PWP2, PPIF, NOLC1, SDF2L1, POLDIP2, ZNF259, RRS1, WDR3, UTP20 355 1797 11759 1.6405292075211424 4.146420017098196E-4 1.0367662257615429E-4 0.0017442743294959762
6 SP_PIR_KEYWORDS acetylation 112 2.1676020901877298 1.4139895960249725E-6 NRBP1, S100A7, CCT2, CCT3, SFRS7, WDR75, MAK16, NUDCD1, RPN1, DDX21, CAB39, HMGCL, DEPDC6, ACAA2, CARS, RAN, NEIL2, ORC1L, PA2G4, KRT19, EIF2S1, HARS, ABAT, DYNLRB1, SRM, OTUD6B, PNPT1, MYBL1, BOP1, PUS7, CSE1L, METTL1, CACYBP, IDH1, NAT10, EIF3J, BRI3BP, MRPS23, TET2, GART, PPIF, TRNT1, CCT4, NOLC1, RRS1, GPATCH4, FABP5, KYNU, UTP15, MBP, BAG5, AKR1C2, NARS2, PRMT5, BAG2, MAGOHB, HIST3H2A, CAP1, MYB, MYC, ABCE1, EXOSC9, SSBP1, SLC3A2, EXOSC2, MCM2, SLC9A3R1, UGT1A1, NCL, FLNB, PRPF4, NRIP1, MCM6, CD3EAP, UMPS, CFL2, IGF2R, COMMD3, TXNRD1, NUP107, SMS, PYCRL, FKBP4, UGDH, NOB1, POLR2D, CCDC58, IARS, UGT1A6, RPA2, NUMA1, MTMR1, UGT1A3, FAM107B, WDR12, UCK2, FEN1, GEMIN4, C21ORF59, DUS3L, GEMIN5, HSPA9, ENO1, C1ORF163, RRP15, PNO1, MAP1B, ILF3, TMED8, PWP2, PHB2, EEF1E1, NLN, PAICS 492 2600 17699 1.5496310193871168 5.767417835532695E-4 5.767417835532695E-4 0.001977905752825748
7 GOTERM_BP_FAT GO:0034660~ncRNA metabolic process 21 0.4064253919101994 1.058034832372384E-5 CARS, EXOSC9, PUS1, UTP18, UTP6, EXOSC2, UTP15, BOP1, PUS7, TRNT1, IARS, PA2G4, NOLC1, METTL1, NARS2, HARS, WDR3, WDR12, TSEN2, GEMIN4, DUS3L 371 225 12596 3.168805031446541 0.019912424511369098 0.019912424511369098 0.018081630316446606
8 GOTERM_BP_FAT GO:0022613~ribonucleoprotein complex biogenesis 18 0.34836462163731374 1.7993204689435034E-5 EXOSC9, UTP18, SNRPD3, UTP6, EXOSC2, UTP15, BOP1, MRTO4, RCL1, PA2G4, NOLC1, PRMT5, WDR77, WDR3, RRS1, WDR12, GEMIN4, GEMIN5 371 177 12596 3.452693133537393 0.03362699895072174 0.01695727404691194 0.03074823838887797
9 GOTERM_CC_FAT GO:0031981~nuclear lumen 70 1.354751306367331 3.9026519927298455E-5 FOSL2, UTP18, LYAR, SNRPD3, ARNT2, PDLIM3, UTP15, CCT2, MCM10, WDR74, WDR75, MAK16, DHX33, DDX21, CIRH1A, TSEN2, MYB, MYC, CDC7, EXOSC9, RBL2, RAN, EXOSC2, TLE1, MCM2, NCL, PRPF4, ORC1L, MRTO4, MCM6, NRIP1, NOC2L, CD3EAP, TNS3, RCL1, PA2G4, PPM1E, NAV2, CFL2, DSCC1, YPEL2, FKBP4, YPEL3, UTP6, NOC3L, NR3C1, MYBL1, BOP1, POLR2D, PPAN, KIAA0020, RPA2, NUMA1, WDR12, NAT10, GEMIN4, GEMIN5, POLR3H, POLR3K, TBX2, PNO1, ILF3, APPL2, FOXP1, PWP2, NOLC1, ZNF259, RRS1, WDR3, UTP20 355 1429 11759 1.6225864634975704 0.012449611673891137 0.0025024151969507136 0.05267616554346377
10 GOTERM_BP_FAT GO:0042254~ribosome biogenesis 14 0.2709502612734662 4.599583439759657E-5 EXOSC9, UTP18, UTP6, EXOSC2, UTP15, BOP1, MRTO4, RCL1, PA2G4, NOLC1, RRS1, WDR12, WDR3, GEMIN4 371 119 12596 3.9942920564452193 0.08372623799782875 0.028726029333315695 0.07858368330486698
11 GOTERM_BP_FAT GO:0034470~ncRNA processing 17 0.3290110315463518 9.2362653303944E-5 EXOSC9, PUS1, UTP18, UTP6, EXOSC2, UTP15, BOP1, PUS7, TRNT1, PA2G4, NOLC1, METTL1, WDR12, WDR3, TSEN2, GEMIN4, DUS3L 371 182 12596 3.171292319540298 0.16103770423001995 0.04294783320097828 0.1577423433651859
12 INTERPRO IPR012340:Nucleic acid-binding, OB-fold 9 0.17418231081865687 1.1272418988482108E-4 RPA2, MRPS17, SSBP1, EIF2S1, NARS2, MRPS12, PNPT1, MCM2, MCM6 438 53 15425 5.980227448953218 0.09525733414280135 0.09525733414280135 0.17525970675313918
13 SP_PIR_KEYWORDS phosphoprotein 240 4.64486162183085 1.253819695018583E-4 OSMR, RUSC1, RAB3GAP1, CCT3, SIDT2, WDR74, PGR, WDR75, SFRS7, MAK16, HOMER3, KIFAP3, WDR77, DHX33, VPS13B, RAPGEF2, AUP1, DEPDC6, ACAA2, TYRO3, RAN, KIAA1804, OPTN, GEM, BCL2L11, NME7, ORC1L, MARK2, KIAA1522, KRT19, NAV2, EIF2S1, SIPA1L1, TGIF2, GRB14, IL1R1, PUS1, ENPP1, ERBB3, ERBB2, NOC3L, DUSP10, BOP1, PDSS1, PUS7, PPAN, STX12, GOLSYN, CDC123, CACYBP, NAT10, GCNT1, BLNK, CCDC86, MOCS2, KLF10, RHBDF1, PPFIBP2, TPD52L1, GART, NOLC1, SYTL2, CHAF1A, UTP20, PDZK1, UTP18, MITF, VPS37A, SLC26A2, SEH1L, BAG2, IL1RAP, NSMCE2, CAP1, TSEN2, MYC, JPH1, CDC7, EXOSC9, CLMN, ZDHHC8, EXOSC2, SLC3A2, TLE1, ARRDC4, RFTN1, MYADM, FLNB, NOC2L, THOC5, NUP107, CLN6, CAB39L, RABGAP1, NOB1, UGDH, STARD10, SLC19A2, GCH1, NUMA1, MTMR1, QSOX2, ARMCX6, C21ORF59, BCAS1, RBM24, RRP15, ILF3, NPY1R, GPR77, RAB31, SLC16A6, SVIL, POLDIP2, UBXN8, NLN, SLC15A4, TJP2, PAICS, SSR3, NRBP1, WFS1, CEP78, MCM10, SLC7A5, RELL1, SLC16A1, DAB2, ELOVL5, ANK3, PGLYRP2, SLC2A1, DDX21, DNAJC1, RET, CARS, RBL2, MGP, TACC1, MRTO4, TNS3, PA2G4, HSPB8, IGSF3, DNTTIP2, MRPS17, OTUD6B, PNPT1, TIPIN, NEDD9, PTRH2, RIOK1, CCNG2, ABCA3, TOMM6, PTK6, METTL1, C2ORF55, OTUD7B, EIF3J, RFX5, TET2, FOXP1, C9ORF142, RRS1, WDR3, GPATCH4, FAM84A, FAM84B, FABP5, FOSL2, LYAR, WWC1, DPH2, MBP, SLC1A4, PRMT1, FAM83A, ATP8B2, MAGOHB, HIST3H2A, CAT, SSBP1, SGK3, C9ORF89, ARID5B, MCM2, LMBRD1, SLC9A3R1, GAL, NCL, MCM6, NRIP1, TMEM38B, STOM, CD3EAP, UMPS, IGF2R, CFL2, PLLP, TXNRD1, MCC, MFSD11, SMS, TMEM194A, FKBP4, CTNND1, NR3C1, COMT, IARS, RNF126, RPA2, TSC22D3, RASGRP1, MLXIP, UCK2, PIK3R3, GEMIN4, HSPA9, DUS3L, ENO1, GEMIN5, SLC12A2, ARMC10, PNO1, MAP1B, GRSF1, RAF1, KIAA0831, BCS1L, MLF1IP, TMED8, FAM60A, PWP2, SH3BP5, TMEM48, ID1, PHB2, TMEM164, IGFBP3 492 7171 17699 1.203968558999493 0.049872460064613655 0.025255141108512236 0.17524468925498304
14 GOTERM_CC_FAT GO:0044429~mitochondrial part 35 0.6773756531836655 1.409969646774704E-4 MRPS17, TIMM17A, MRPS12, PNPT1, BCL2L1, NR3C1, TOMM6, SLC25A25, NARS2, MRPL16, MRPL36, MLXIP, CAT, HMGCL, HSPA9, ACAA2, MRPL3, SSBP1, RAF1, BCS1L, C10ORF2, BCL2L11, PPIF, SLC25A32, SLC25A33, PPM1K, PHB2, POLDIP2, FDX1L, ABAT, SLC25A19, BIK, NLN, SLC25A15, PMPCB 355 578 11759 2.0057751352405084 0.04425411957845071 0.007515485889737827 0.19018984554939333
15 GOTERM_CC_FAT GO:0005739~mitochondrion 54 1.045093864911941 1.4304035042412907E-4 KYNU, TIMM17A, PMAIP1, AGPAT5, SLC25A25, NARS2, MRPL36, CAT, HMGCL, ACAA2, ABCE1, MRPL3, SSBP1, PISD, MRPS2, C10ORF2, BCL2L11, DHRS2, SLC25A32, SLC25A33, PPM1K, FDX1L, ABAT, CTSD, PMPCB, MRPS17, MRPS12, PNPT1, BCL2L1, NR3C1, PTRH2, TSC22D3, TOMM6, MRPL15, MRPL16, MLXIP, FEN1, HSPA9, MRPS23, RAF1, ILF3, BCS1L, SH3BP5, TRNT1, PPIF, CHCHD10, PHB2, HEBP1, POLDIP2, SLC25A19, BIK, NLN, SLC25A15, PDZK1 355 1057 11759 1.692235532399696 0.04488090236953113 0.006538421845438291 0.19294369087173857
16 COG_ONTOLOGY Translation, ribosomal structure and biogenesis 9 0.17418231081865687 1.437077761111865E-4 TRNT1, KIAA0020, CARS, EXOSC9, PUS1, EIF2S1, HARS, EXOSC2, EIF2B2 46 68 1879 5.406329923273658 0.0024402255492194103 0.0024402255492194103 0.10400517217425964
17 GOTERM_CC_FAT GO:0043232~intracellular non-membrane-bounded organelle 103 1.9934197793690729 2.1891137787469198E-4 CCDC85B, SNRPD3, CEP78, PDLIM3, CCT2, CCT3, WDR74, WDR75, MAK16, ANK3, IFT20, HOMER3, KIFAP3, MRPL36, DHX33, DDX21, RBL2, RAN, NEIL2, ORC1L, TACC1, C10ORF2, MRTO4, TNS3, RCL1, PA2G4, KRT19, NAV2, PRDM6, CSTA, DYNLRB1, DSCC1, MRPS17, LITAF, MRPS12, NOC3L, TIPIN, NEDD9, MYBL1, BOP1, PPAN, GOLSYN, NAT10, MRPS23, MYO1B, FOXP1, NOLC1, RRS1, WDR3, UTP20, FOSL2, UTP18, LYAR, UTP15, RHOQ, SLC1A4, SEH1L, MAP1LC3B, HIST3H2A, CIRH1A, CAP1, TSEN2, MYC, EXOSC9, MRPL3, SSBP1, DYNLT3, EXOSC2, MCM2, SLC9A3R1, FLNB, NCL, MRPS2, NOC2L, CD3EAP, STOM, PPM1E, SGCG, CFL2, NUP107, RABGAP1, FKBP4, YPEL2, UTP6, YPEL3, NR3C1, RPA2, KIAA0020, NUMA1, MRPL15, MRPL16, WDR12, GEMIN4, HSPA9, PNO1, MAP1B, ILF3, MLF1IP, PWP2, PTP4A1, SVIL, POLDIP2, ZNF259 355 2460 11759 1.3868968281232108 0.06786557785949832 0.008746307173958412 0.29514433417807684
18 GOTERM_CC_FAT GO:0043228~non-membrane-bounded organelle 103 1.9934197793690729 2.1891137787469198E-4 CCDC85B, SNRPD3, CEP78, PDLIM3, CCT2, CCT3, WDR74, WDR75, MAK16, ANK3, IFT20, HOMER3, KIFAP3, MRPL36, DHX33, DDX21, RBL2, RAN, NEIL2, ORC1L, TACC1, C10ORF2, MRTO4, TNS3, RCL1, PA2G4, KRT19, NAV2, PRDM6, CSTA, DYNLRB1, DSCC1, MRPS17, LITAF, MRPS12, NOC3L, TIPIN, NEDD9, MYBL1, BOP1, PPAN, GOLSYN, NAT10, MRPS23, MYO1B, FOXP1, NOLC1, RRS1, WDR3, UTP20, FOSL2, UTP18, LYAR, UTP15, RHOQ, SLC1A4, SEH1L, MAP1LC3B, HIST3H2A, CIRH1A, CAP1, TSEN2, MYC, EXOSC9, MRPL3, SSBP1, DYNLT3, EXOSC2, MCM2, SLC9A3R1, FLNB, NCL, MRPS2, NOC2L, CD3EAP, STOM, PPM1E, SGCG, CFL2, NUP107, RABGAP1, FKBP4, YPEL2, UTP6, YPEL3, NR3C1, RPA2, KIAA0020, NUMA1, MRPL15, MRPL16, WDR12, GEMIN4, HSPA9, PNO1, MAP1B, ILF3, MLF1IP, PWP2, PTP4A1, SVIL, POLDIP2, ZNF259 355 2460 11759 1.3868968281232108 0.06786557785949832 0.008746307173958412 0.29514433417807684
19 GOTERM_BP_FAT GO:0006364~rRNA processing 11 0.2128894910005806 2.995388308366497E-4 PA2G4, EXOSC9, NOLC1, UTP18, UTP6, EXOSC2, UTP15, WDR12, WDR3, BOP1, GEMIN4 371 90 12596 4.149625636418089 0.4341966032305815 0.10765435166825932 0.5107182696174162
20 GOTERM_CC_FAT GO:0042470~melanosome 11 0.2128894910005806 3.0145703392284065E-4 SLC1A4, STOM, LAMP1, CCT4, RAB5B, RAN, SLC2A1, RPN1, SLC3A2, CTSD, SYTL2 355 88 11759 4.140492957746479 0.09224639421611802 0.010695975365263344 0.4062258430625132
21 GOTERM_CC_FAT GO:0048770~pigment granule 11 0.2128894910005806 3.0145703392284065E-4 SLC1A4, STOM, LAMP1, CCT4, RAB5B, RAN, SLC2A1, RPN1, SLC3A2, CTSD, SYTL2 355 88 11759 4.140492957746479 0.09224639421611802 0.010695975365263344 0.4062258430625132
22 SP_PIR_KEYWORDS mitochondrion 41 0.7934971937294368 3.0191988806390556E-4 MRPS17, TIMM17A, MRPS12, PNPT1, BCL2L1, PMAIP1, PTRH2, TSC22D3, MRPL15, SLC25A25, TOMM6, NARS2, MRPL16, MRPL36, MLXIP, HMGCL, HSPA9, ACAA2, ABCE1, MRPL3, SSBP1, MRPS23, BCS1L, PISD, MRPS2, C10ORF2, BCL2L11, TRNT1, SH3BP5, PPIF, SLC25A32, CHCHD10, SLC25A33, PPM1K, PHB2, FDX1L, ABAT, SLC25A19, NLN, SLC25A15, PMPCB 492 809 17699 1.823135558302431 0.11591486446913846 0.04023546880037754 0.42150599752606155
23 GOTERM_BP_FAT GO:0016072~rRNA metabolic process 11 0.2128894910005806 4.2676575946136284E-4 PA2G4, EXOSC9, NOLC1, UTP18, UTP6, EXOSC2, UTP15, WDR12, WDR3, BOP1, GEMIN4 371 94 12596 3.973045822102426 0.5557886745812259 0.12649592004427224 0.7268982164718274
24 UP_SEQ_FEATURE short sequence motif:BH3 5 0.09676795045480936 8.229633880676938E-4 BOK, BIK, BCL2L1, PMAIP1, BCL2L11 492 16 17662 11.2182418699187 0.6765618351885978 0.6765618351885978 1.3439518086308389
25 UP_SEQ_FEATURE domain:Leucine-zipper 11 0.2128894910005806 9.179741851709047E-4 MAFF, TSC22D3, FOSL2, MITF, MLXIP, CREB3L4, BIK, MYB, MYC, GEMIN4, FOXP1 492 109 17662 3.622771686432461 0.7160964231034743 0.46717397126592464 1.4980135519399695
26 GOTERM_CC_FAT GO:0031980~mitochondrial lumen 17 0.3290110315463518 0.001287432967691556 MRPS17, MRPL3, SSBP1, MRPS12, NR3C1, C10ORF2, PPIF, PPM1K, NARS2, POLDIP2, MRPL16, MRPL36, FDX1L, ABAT, PMPCB, HMGCL, HSPA9 355 225 11759 2.5026979655712047 0.33868978482038936 0.04050984460739304 1.7242225463910743
27 GOTERM_CC_FAT GO:0005759~mitochondrial matrix 17 0.3290110315463518 0.001287432967691556 MRPS17, MRPL3, SSBP1, MRPS12, NR3C1, C10ORF2, PPIF, PPM1K, NARS2, POLDIP2, MRPL16, MRPL36, FDX1L, ABAT, PMPCB, HMGCL, HSPA9 355 225 11759 2.5026979655712047 0.33868978482038936 0.04050984460739304 1.7242225463910743
28 SP_PIR_KEYWORDS rrna processing 8 0.154828720727695 0.001313288357241543 PA2G4, EXOSC9, UTP18, UTP6, EXOSC2, UTP15, WDR12, BOP1 492 60 17699 4.796476964769648 0.41501776648655053 0.12544793600658422 1.8214747773056428
29 SP_PIR_KEYWORDS nucleus 144 2.78691697309851 0.0015254527393899707 C15ORF48, CCDC85B, RUSC1, SNRPD3, ARNT2, MCM10, PGR, WDR74, SFRS7, WDR75, MAK16, WDR77, DHX33, DDX21, CREB3L4, DNAJC1, RBL2, RAN, NEIL2, ORC1L, TACC1, MRTO4, RCL1, PA2G4, NAV2, PRDM6, TGIF2, DNTTIP2, DSCC1, PUS1, SOX3, NOC3L, TIPIN, DUSP10, NEDD9, BCL2L1, BOP1, MYBL1, CCNG1, PPAN, CSE1L, LHX1, METTL1, PTK6, CACYBP, OTUD7B, NAT10, MAFF, CCDC86, KLF9, RFX5, KLF10, FOXP1, NOLC1, WDR3, RRS1, CHAF1A, UTP20, FOSL2, UTP18, LYAR, MITF, VPS37A, UTP15, PRMT1, SEH1L, PRMT5, MAGOHB, NSMCE2, HIST3H2A, CIRH1A, MYB, TSEN2, MYC, CDC7, EGR3, EXOSC9, C9ORF89, ARID5B, DYNLT3, EXOSC2, TLE1, MCM2, NCL, PRPF4, KLHDC2, MCM6, NOC2L, NRIP1, MXD4, CD3EAP, DHRS2, PPM1E, HOXC13, CFL2, TXNRD1, MCC, SIAH2, NUP107, THOC5, NXT1, FKBP4, YPEL2, YPEL3, UTP6, NOB1, WBSCR22, CTNND1, NR3C1, POLR2D, GCH1, KIAA0020, RPA2, ZFP36L2, NUMA1, WDR12, HBP1, MLXIP, QSOX2, FEN1, GEMIN4, ENO1, GEMIN5, RBM24, POLR3H, POLR3K, TBX2, PNO1, ILF3, MLF1IP, APPL2, PWP2, HARBI1, TMEM48, ID1, PHB2, EEF1E1, POLDIP2, ZNF259, ID3, NR5A2, ZNF766, TJP2, TP53INP1 492 4128 17699 1.2548922291548497 0.4635918373514052 0.11712529204784272 2.112830803667576
30 SMART SM00337:BCL 5 0.09676795045480936 0.0016453332542309945 BOK, BIK, BCL2L1, PMAIP1, BCL2L11 217 21 8614 9.451393460610051 0.25283096131154403 0.25283096131154403 2.0022939445594856
31 GOTERM_BP_FAT GO:0010033~response to organic substance 36 0.6967292432746275 0.00217299025305287 KYNU, IL1R1, ENPP1, OSMR, ERBB3, ERBB2, ARNT2, RHOQ, BCL2L1, NR3C1, COMT, PMAIP1, TIMP3, GCH1, UGT1A6, CDKN2B, UGT1A3, IDH1, CREB3L4, EIF2B2, PIK3R3, MYC, SOCS2, KLF10, MAP1B, MGP, NPY1R, GAL, UGT1A1, ABCG1, GART, KRT19, BTG2, ADM, ID1, ABAT, ID3, TJP2 371 717 12596 1.7046769445916836 0.9840029210131064 0.4460961495212252 3.6496920488000018
32 GOTERM_BP_FAT GO:0008202~steroid metabolic process 15 0.2903038513644281 0.002228312193840812 ACAA2, CYB5R1, NR3C1, COMT, UGT1A1, ABCG1, SC4MOL, DHRS2, UGT1A6, AKR1C2, ADM, UGT1A3, CYP2R1, CAT, UGT2B15, NR5A2, CLN6 371 199 12596 2.5591569708380177 0.9856031823382349 0.41145006912114024 3.74095113873949
33 GOTERM_CC_FAT GO:0031967~organelle envelope 32 0.61931488291078 0.0024569790022903664 NXT1, TIMM17A, PNPT1, BCL2L1, CSE1L, TOMM6, SLC25A25, PTGES, SEH1L, CACYBP, MLXIP, CAT, HMGCL, ACAA2, RAN, RAF1, BCS1L, BCL2L11, TMEM38B, PPIF, DHRS2, SLC25A32, TMEM48, SLC25A33, PHB2, IGF2R, SLC25A19, BIK, NLN, NUP107, SLC25A15, PMPCB 355 602 11759 1.760741191334051 0.5460012105754424 0.06927119707268581 3.266659247129522
34 INTERPRO IPR000712:Apoptosis regulator Bcl-2, BH 5 0.09676795045480936 0.0025930149853382227 BOK, BIK, BCL2L1, PMAIP1, BCL2L11 438 21 15425 8.384974994564036 0.9002998215729939 0.6842466493811885 3.9595573974661624
35 GOTERM_CC_FAT GO:0031975~envelope 32 0.61931488291078 0.0025956234888141983 NXT1, TIMM17A, PNPT1, BCL2L1, CSE1L, TOMM6, SLC25A25, PTGES, SEH1L, CACYBP, MLXIP, CAT, HMGCL, ACAA2, RAN, RAF1, BCS1L, BCL2L11, TMEM38B, PPIF, DHRS2, SLC25A32, TMEM48, SLC25A33, PHB2, IGF2R, SLC25A19, BIK, NLN, NUP107, SLC25A15, PMPCB 355 604 11759 1.754910922488574 0.5658122979375861 0.06716150445553137 3.448014515305442
36 SP_PIR_KEYWORDS dna replication 9 0.17418231081865687 0.002847691214723561 RPA2, SSBP1, MCM2, MCM10, CHAF1A, ORC1L, C10ORF2, MCM6, DSCC1 492 87 17699 3.721404541631623 0.6876139353475446 0.1762755784689627 3.910586817288564
37 GOTERM_BP_FAT GO:0006396~RNA processing 28 0.5419005225469324 0.004847408490656922 PUS1, UTP18, SNRPD3, PNPT1, UTP6, UTP15, BOP1, POLR2D, PUS7, SFRS7, PPAN, PRMT5, METTL1, WDR77, MAGOHB, WDR12, TSEN2, GEMIN4, GEMIN5, DUS3L, EXOSC9, EXOSC2, GRSF1, PRPF4, TRNT1, PA2G4, NOLC1, WDR3 371 539 12596 1.7637133755732137 0.9999026628885598 0.6416947583077536 7.969474692537604
38 GOTERM_CC_FAT GO:0043209~myelin sheath 4 0.0774143603638475 0.004861293752264274 ERBB2, PLLP, PMP22, MBP 355 12 11759 11.041314553990611 0.7907615140271278 0.11337155738989069 6.367394637009105
39 UP_SEQ_FEATURE repeat:WD 5 15 0.2903038513644281 0.005171620074198351 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 492 230 17662 2.3411983032873804 0.9991820331316031 0.9064784051558347 8.168431681453592
40 GOTERM_CC_FAT GO:0043218~compact myelin 3 0.05806077027288562 0.005208769786567549 PLLP, PMP22, MBP 355 4 11759 24.842957746478874 0.8129510352808095 0.11285050886964809 6.8078288068923465
41 SP_PIR_KEYWORDS deafness 9 0.17418231081865687 0.005896419155482764 WFS1, NDP, MITF, MGP, BCS1L, PMP22, SLC19A2, ANKH, TMPRSS3 492 98 17699 3.303695868591339 0.9104411782070712 0.29156306420765654 7.939545630477474
42 SMART SM00320:WD40 15 0.2903038513644281 0.006143369818539343 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 217 262 8614 2.272663313047455 0.6640289483834827 0.4203699010433315 7.289751422109914
43 UP_SEQ_FEATURE repeat:WD 6 13 0.25159667118250434 0.006718377682626672 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR12, WDR3, CIRH1A, GEMIN5 492 189 17662 2.4692003269239042 0.9999031140676099 0.9007877769989033 10.487011449881468
44 GOTERM_BP_FAT GO:0006399~tRNA metabolic process 10 0.19353590090961872 0.0067452055199603185 TRNT1, IARS, CARS, PUS1, NARS2, METTL1, HARS, TSEN2, PUS7, DUS3L 371 115 12596 2.9523028243290756 0.9999974157540801 0.7237938248243307 10.923511261920748
45 GOTERM_BP_FAT GO:0006261~DNA-dependent DNA replication 7 0.1354751306367331 0.006895230579153731 RPA2, TIPIN, MCM2, ORC1L, FEN1, C10ORF2, MCM6 371 58 12596 4.0975927130774235 0.9999980607958706 0.6975225187750991 11.153185942851906
46 GOTERM_CC_FAT GO:0031970~organelle envelope lumen 6 0.11612154054577124 0.007396974752908273 PTGES, IGF2R, PNPT1, CACYBP, NLN, CAT 355 41 11759 4.847406389556853 0.9077501146123059 0.14690436003848717 9.537649034953999
47 INTERPRO IPR004910:Yippee-like protein 3 0.05806077027288562 0.007566115038214055 YPEL5, YPEL2, YPEL3 438 5 15425 21.13013698630137 0.9988223759172521 0.894398790393147 11.146352289795958
48 GOTERM_BP_FAT GO:0008283~cell proliferation 23 0.44513257209212304 0.008514021034284596 OSMR, KLF10, NDP, ERBB2, RAF1, BOP1, APPL2, CXCL12, ZFP36L2, DAB2, PA2G4, CSE1L, PRMT5, TGFBI, ZNF259, TGFA, WDR12, TXNRD1, AREG, IFRD2, PDZK1, MYC, IGFBP4 371 430 12596 1.8160095279884658 0.9999999127464816 0.7419333332619509 13.59619892664934
49 GOTERM_BP_FAT GO:0000387~spliceosomal snRNP biogenesis 5 0.09676795045480936 0.008585583673468903 PRMT5, SNRPD3, WDR77, GEMIN4, GEMIN5 371 28 12596 6.0627647285329225 0.999999923933789 0.7166003118646767 13.702724781465726
50 GOTERM_MF_FAT GO:0019838~growth factor binding 9 0.17418231081865687 0.008884459756386125 IL1R1, OSMR, ERBB3, ERBB2, IGF2R, IL1RAP, FGFBP2, IGFBP3, IGFBP4 336 105 12042 3.071938775510204 0.9965719612266232 0.9965719612266232 12.440700022340568
51 PIR_SUPERFAMILY PIRSF028804:protein yippee-like 3 0.05806077027288562 0.009237681336162037 YPEL5, YPEL2, YPEL3 214 5 6776 18.998130841121494 0.9044394468784814 0.9044394468784814 11.378021159471952
52 UP_SEQ_FEATURE repeat:WD 4 15 0.2903038513644281 0.009464687843327196 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 492 247 17662 2.1800631973931077 0.9999978237004521 0.9262870597917977 14.46881875150805
53 SP_PIR_KEYWORDS Chaperone 11 0.2128894910005806 0.009536600669961537 BAG5, ABCE1, CCT4, HSPB8, BAG2, CCT2, BCS1L, CCT3, CHAF1A, DNAJC1, HSPA9 492 151 17699 2.620591719162225 0.9799515817154427 0.38657705829416056 12.544536870526857
54 GOTERM_BP_FAT GO:0009725~response to hormone stimulus 20 0.38707180181923745 0.011920886080302001 ENPP1, SOCS2, ERBB3, ERBB2, ARNT2, MAP1B, RHOQ, MGP, BCL2L1, NPY1R, GAL, TIMP3, UGT1A1, ABCG1, UGT1A6, KRT19, BTG2, UGT1A3, ADM, IDH1, EIF2B2, PIK3R3 371 367 12596 1.8502170288710829 0.9999999998743802 0.8037589415076629 18.532607672282875
55 INTERPRO IPR001993:Mitochondrial substrate carrier 6 0.11612154054577124 0.012222404752525227 MRPS17, SLC25A32, SLC25A25, SLC25A33, SLC25A19, SLC25A15 438 49 15425 4.312272854347218 0.9999819139346822 0.934786723079817 17.41627667939246
56 GOTERM_CC_FAT GO:0005641~nuclear envelope lumen 3 0.05806077027288562 0.012510457046805472 PTGES, IGF2R, CACYBP 355 6 11759 16.561971830985915 0.9824234263899769 0.22320148156834196 15.63072460976117
57 UP_SEQ_FEATURE repeat:WD 3 15 0.2903038513644281 0.014821541497263122 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 492 261 17662 2.0631249415942436 0.9999999987148976 0.9670271650636336 21.761580773175083
58 GOTERM_MF_FAT GO:0016796~exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4 0.0774143603638475 0.014854521373244865 EXOSC9, PNPT1, EXOSC2, FEN1 336 19 12042 7.545112781954886 0.9999265089681971 0.9914273089520926 19.97235242164145
59 GOTERM_BP_FAT GO:0043434~response to peptide hormone stimulus 11 0.2128894910005806 0.01548983171958068 SOCS2, BTG2, ENPP1, ADM, ERBB3, MAP1B, RHOQ, BCL2L1, PIK3R3, GAL, EIF2B2 371 154 12596 2.425105891413169 0.9999999999998707 0.8617153076865014 23.418363544886144
60 INTERPRO IPR017986:WD40 repeat, region 14 0.2709502612734662 0.016180546597075032 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 438 234 15425 2.1069937165827577 0.9999994884591533 0.9448207156481641 22.418042245093282
61 GOTERM_CC_FAT GO:0005832~chaperonin-containing T-complex 3 0.05806077027288562 0.017168546505289047 CCT4, CCT2, CCT3 355 7 11759 14.195975855130783 0.9961472218668459 0.2789145941472092 20.848174319394698
62 GOTERM_BP_FAT GO:0042219~cellular amino acid derivative catabolic process 4 0.0774143603638475 0.017176849944190616 KYNU, PCYOX1L, ABAT, COMT 371 19 12596 7.147680522059868 0.999999999999995 0.8723617623445623 25.630549715229844
63 INTERPRO IPR001680:WD40 repeat 15 0.2903038513644281 0.017480659744684234 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 438 262 15425 2.0162344452577643 0.9999998419102009 0.9264667138687919 23.998105337870545
64 INTERPRO IPR019781:WD40 repeat, subgroup 14 0.2709502612734662 0.018342114200604002 UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 438 238 15425 2.0715820574805264 0.9999999274526088 0.9044812064357161 25.028413013956563
65 UP_SEQ_FEATURE repeat:WD 1 15 0.2903038513644281 0.019229692425193068 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 492 270 17662 1.9943541102077686 0.9999999999972535 0.9776952536082781 27.32047722283569
66 UP_SEQ_FEATURE repeat:WD 2 15 0.2903038513644281 0.019229692425193068 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 492 270 17662 1.9943541102077686 0.9999999999972535 0.9776952536082781 27.32047722283569
67 KEGG_PATHWAY hsa00240:Pyrimidine metabolism 8 0.154828720727695 0.019392403121619523 UMPS, POLR3H, POLR3K, PNPT1, TXNRD1, UCK2, POLR2D, NME7 139 94 4719 2.8893310883208327 0.942679891476622 0.942679891476622 20.7655126061125
68 KEGG_PATHWAY hsa03030:DNA replication 5 0.09676795045480936 0.01997211305906789 RPA2, SSBP1, MCM2, FEN1, MCM6 139 36 4719 4.715227817745803 0.9474211190329963 0.770699147478681 21.320472168156957
69 SP_PIR_KEYWORDS wd repeat 15 0.2903038513644281 0.020024435590552107 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 492 272 17699 1.9838369799139166 0.9997394922370488 0.6002781836735952 24.644200787971116
70 GOTERM_BP_FAT GO:0006260~DNA replication 12 0.23224308109154249 0.020031082364289136 CDC7, RPA2, SSBP1, TIPIN, MCM2, MCM10, CHAF1A, ORC1L, FEN1, C10ORF2, MCM6, DSCC1 371 184 12596 2.2142271182468067 1.0 0.8959292960651413 29.23687931057737
71 GOTERM_CC_FAT GO:0005740~mitochondrial envelope 21 0.4064253919101994 0.02031161380932705 ACAA2, TIMM17A, PNPT1, RAF1, BCS1L, BCL2L1, BCL2L11, PPIF, SLC25A32, TOMM6, SLC25A25, SLC25A33, PHB2, SLC25A19, MLXIP, BIK, NLN, CAT, SLC25A15, PMPCB, HMGCL 355 404 11759 1.7217891507460605 0.9986220449149937 0.30646463041185146 24.198095748635474
72 GOTERM_BP_FAT GO:0042552~myelination 5 0.09676795045480936 0.02056969192659258 ERBB2, PLLP, PMP22, EIF2B2, MBP 371 36 12596 4.715483677747829 1.0 0.888646103160791 29.898674983081076
73 GOTERM_BP_FAT GO:0042127~regulation of cell proliferation 34 0.6580220630927036 0.02220489883416118 FOSL2, OSMR, ERBB3, ERBB2, ARNT2, MITF, TIPIN, BCL2L1, COMT, PGR, S1PR3, CDKN2B, PTGES, LHX1, KIFAP3, CDC123, TGFA, MYC, CDC7, TBX2, KLF10, GAL, FOXP1, MXD4, DHRS2, TNS3, BTG2, ADM, BTG1, EEF1E1, PMP22, UTP20, NR5A2, IGFBP3 371 781 12596 1.4780414907972708 1.0 0.8942519329990928 31.87235217824481
74 GOTERM_BP_FAT GO:0006412~translation 17 0.3290110315463518 0.023634289592306703 MRPS17, CARS, MRPL3, PTRH1, MRPS12, PTRH2, MRPS2, IARS, MRPL15, EIF2S1, EEF1E1, NARS2, MRPL16, HARS, MRPL36, EIF3J, EIF2B2 371 315 12596 1.8323022290677278 1.0 0.8970396742927125 33.55464141808149
75 GOTERM_BP_FAT GO:0009612~response to mechanical stimulus 6 0.11612154054577124 0.023903146859971212 SLC12A2, BTG2, MAP1B, MGP, TIMP3, MYC 371 56 12596 3.6376588371197536 1.0 0.8880926979655588 33.86666440686895
76 INTERPRO IPR019775:WD40 repeat, conserved site 15 0.2903038513644281 0.023929450768401608 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 438 273 15425 1.9349942295147775 0.9999999995436336 0.9320148265937527 31.40014614575125
77 UP_SEQ_FEATURE compositionally biased region:Poly-Phe 3 0.05806077027288562 0.024393836794263747 WFS1, SIDT2, AUP1 492 9 17662 11.966124661246612 0.999999999999998 0.9854814423362132 33.36057621724981
78 UP_SEQ_FEATURE domain:S1 motif 3 0.05806077027288562 0.024393836794263747 EIF2S1, PNPT1, EXOSC2 492 9 17662 11.966124661246612 0.999999999999998 0.9854814423362132 33.36057621724981
79 INTERPRO IPR019782:WD40 repeat 2 13 0.25159667118250434 0.024575736515115097 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, GEMIN5 438 222 15425 2.062250606771155 0.9999999997465593 0.9141453084929069 32.103535215891554
80 GOTERM_BP_FAT GO:0019725~cellular homeostasis 22 0.4257789820011612 0.02808592469193097 ENPP1, SLC12A2, WFS1, ERBB2, BCL2L1, NPY1R, SLC9A3R1, CXCL12, TMPRSS3, MBP, S1PR3, ADM, PLLP, TXNRD1, STC1, QSOX2, PMP22, EIF2B2, JPH1, MYC, ABCA12, CLN6 371 456 12596 1.6380101196387196 1.0 0.9147026308591465 38.546801760431556
81 GOTERM_BP_FAT GO:0008366~axon ensheathment 5 0.09676795045480936 0.029141360862368702 ERBB2, PLLP, PMP22, EIF2B2, MBP 371 40 12596 4.243935309973046 1.0 0.9132208407575864 39.67746399602665
82 GOTERM_BP_FAT GO:0007272~ensheathment of neurons 5 0.09676795045480936 0.029141360862368702 ERBB2, PLLP, PMP22, EIF2B2, MBP 371 40 12596 4.243935309973046 1.0 0.9132208407575864 39.67746399602665
83 GOTERM_BP_FAT GO:0009719~response to endogenous stimulus 20 0.38707180181923745 0.02984506358937568 ENPP1, SOCS2, ERBB3, ERBB2, ARNT2, MAP1B, RHOQ, MGP, BCL2L1, NPY1R, GAL, TIMP3, UGT1A1, ABCG1, UGT1A6, KRT19, BTG2, UGT1A3, ADM, IDH1, EIF2B2, PIK3R3 371 405 12596 1.6766164187547836 1.0 0.9092795302235193 40.42040888449443
84 INTERPRO IPR002194:Chaperonin TCP-1, conserved site 3 0.05806077027288562 0.030999804781554906 CCT4, CCT2, CCT3 438 10 15425 10.565068493150685 0.9999999999992829 0.9389677794014994 38.73765994615841
85 UP_SEQ_FEATURE repeat:WD 9 5 0.09676795045480936 0.031000938992190114 WDR75, WDR3, CIRH1A, PWP2, GEMIN5 492 43 17662 4.174229532993005 1.0 0.9917473911377216 40.402262289260904
86 SP_PIR_KEYWORDS cell cycle 21 0.4064253919101994 0.0314150988259652 CDC7, PPP6C, RABGAP1, RBL2, RAN, TIPIN, NEDD9, MCM2, TET2, CCNG1, CCNG2, APPL2, TACC1, MCM6, CDKN2B, SEH1L, PTP4A1, CDC123, SIAH2, CHAF1A, DSCC1 492 458 17699 1.6494434977100865 0.9999977910827016 0.728094529296458 36.013166848656574
87 SP_PIR_KEYWORDS trna processing 6 0.11612154054577124 0.03220251001232269 TRNT1, PUS1, METTL1, TSEN2, PUS7, DUS3L 492 64 17699 3.3725228658536586 0.9999984148422126 0.7030154453062603 36.73697997238068
88 GOTERM_BP_FAT GO:0043586~tongue development 3 0.05806077027288562 0.03313228601165426 HOXC13, ERBB3, ERBB2 371 10 12596 10.18544474393531 1.0 0.9228544078636581 43.77825812094167
89 GOTERM_BP_FAT GO:0030858~positive regulation of epithelial cell differentiation 3 0.05806077027288562 0.03313228601165426 CDKN2B, BTG1, IL20 371 10 12596 10.18544474393531 1.0 0.9228544078636581 43.77825812094167
90 GOTERM_MF_FAT GO:0000175~3'-5'-exoribonuclease activity 3 0.05806077027288562 0.035952410053867435 EXOSC9, PNPT1, EXOSC2 336 11 12042 9.77435064935065 0.9999999999229755 0.9995745227620993 42.02054457847848
91 INTERPRO IPR017998:Chaperone, tailless complex polypeptide 1 3 0.05806077027288562 0.03718979178327543 CCT4, CCT2, CCT3 438 11 15425 9.604607721046078 0.9999999999999976 0.9530879415705903 44.55196538162384
92 SP_PIR_KEYWORDS transit peptide 21 0.4064253919101994 0.03727798570859327 ACAA2, MRPS17, SSBP1, MRPS12, PNPT1, PTRH2, C10ORF2, TRNT1, PPIF, CHCHD10, MRPL15, PPM1K, NARS2, MRPL16, MRPL36, FDX1L, ABAT, NLN, PMPCB, HMGCL, HSPA9 492 467 17699 1.6176555073901917 0.9999998144895625 0.7251911619749237 41.22312213051924
93 PIR_SUPERFAMILY PIRSF002584:molecular chaperone t-complex-type 3 0.05806077027288562 0.03748002139688133 CCT4, CCT2, CCT3 214 10 6776 9.499065420560747 0.9999365155382893 0.9920322862933769 39.17636453005012
94 GOTERM_CC_FAT GO:0055029~nuclear DNA-directed RNA polymerase complex 4 0.0774143603638475 0.038119144174238236 CD3EAP, POLR3H, POLR3K, POLR2D 355 25 11759 5.299830985915493 0.9999961811619611 0.48139286642364243 40.827026476156306
95 GOTERM_CC_FAT GO:0000428~DNA-directed RNA polymerase complex 4 0.0774143603638475 0.038119144174238236 CD3EAP, POLR3H, POLR3K, POLR2D 355 25 11759 5.299830985915493 0.9999961811619611 0.48139286642364243 40.827026476156306
96 SP_PIR_KEYWORDS multifunctional enzyme 6 0.11612154054577124 0.04029767114736884 UMPS, ENPP1, BLVRB, NEIL2, PAICS, GART 492 68 17699 3.1741391678622666 0.9999999485113077 0.7249811568330351 43.750121670467166
97 KEGG_PATHWAY hsa04012:ErbB signaling pathway 7 0.1354751306367331 0.040955076048494674 ERBB3, ERBB2, TGFA, RAF1, AREG, PIK3R3, MYC 139 87 4719 2.731580253038948 0.9977690653372121 0.8693340940919103 39.16670529339426
98 GOTERM_MF_FAT GO:0042803~protein homodimerization activity 16 0.30965744145539 0.041051439374184845 CARS, KYNU, NRBP1, ENPP1, ERBB3, KIAA1804, TPD52L1, ABCG1, FOXP1, GCH1, GPD1L, GLA, PRDM6, ABAT, CAT, CLN6 336 328 12042 1.7482578397212543 0.9999999999973587 0.9987251633301619 46.421939570096015
99 GOTERM_CC_FAT GO:0030880~RNA polymerase complex 4 0.0774143603638475 0.042159083881037486 CD3EAP, POLR3H, POLR3K, POLR2D 355 26 11759 5.095991332611051 0.9999990110449687 0.49909100883483104 44.09569034017895
100 GOTERM_BP_FAT GO:0006873~cellular ion homeostasis 18 0.34836462163731374 0.04224139147985075 ENPP1, WFS1, ERBB2, BCL2L1, NPY1R, SLC9A3R1, CXCL12, TMPRSS3, MBP, S1PR3, ADM, PLLP, STC1, PMP22, EIF2B2, JPH1, MYC, CLN6 371 367 12596 1.6651953259839745 1.0 0.9573881956352305 52.17641326847124
101 GOTERM_MF_FAT GO:0016896~exoribonuclease activity, producing 5'-phosphomonoesters 3 0.05806077027288562 0.042364031877615047 EXOSC9, PNPT1, EXOSC2 336 12 12042 8.959821428571429 0.9999999999988947 0.9959383997627934 47.50338736042779
102 GOTERM_MF_FAT GO:0004532~exoribonuclease activity 3 0.05806077027288562 0.042364031877615047 EXOSC9, PNPT1, EXOSC2 336 12 12042 8.959821428571429 0.9999999999988947 0.9959383997627934 47.50338736042779
103 GOTERM_MF_FAT GO:0046983~protein dimerization activity 23 0.44513257209212304 0.042661440666312 KYNU, CARS, FOSL2, NRBP1, ENPP1, ERBB3, KIAA1804, ERBB2, ARNT2, TPD52L1, BCL2L1, PDSS1, ABCG1, FOXP1, GCH1, GPD1L, GLA, BOK, PRDM6, ABAT, CREB3L4, CAT, CLN6 336 534 12042 1.5436396468699842 0.9999999999990928 0.9901610563842035 47.745576824665804
104 SP_PIR_KEYWORDS ribosome biogenesis 5 0.09676795045480936 0.04364074802909146 RCL1, WDR12, RRS1, BOP1, MRTO4 492 48 17699 3.7472476287262872 0.9999999876007912 0.7275778434406863 46.42988176927698
105 INTERPRO IPR015943:WD40/YVTN repeat-like 15 0.2903038513644281 0.04388811542602682 UTP18, UTP15, TLE1, BOP1, PRPF4, PWP2, WDR74, WDR75, SEH1L, WDR77, WSB2, WDR12, WDR3, CIRH1A, GEMIN5 438 297 15425 1.7786310594529773 1.0 0.963888541867316 50.25981070787555
106 BIOCARTA h_btg2Pathway:BTG family proteins and cell cycle regulation 3 0.05806077027288562 0.044106658815728755 PRMT1, BTG2, BTG1 50 10 1418 8.508 0.9879739014958838 0.9879739014958838 39.272551493105354
107 SMART SM00353:HLH 7 0.1354751306367331 0.044534239085473 ID1, MITF, ARNT2, MLXIP, ID3, MYC, MXD4 217 103 8614 2.697776385844034 0.999685168783761 0.9319712336069718 42.854200211426594
108 GOTERM_BP_FAT GO:0006865~amino acid transport 7 0.1354751306367331 0.044735723513050774 SLC1A4, SLC25A32, SLC7A1, SLC3A2, SLC7A5, SLC25A15, PDZK1 371 88 12596 2.7006861063464838 1.0 0.9601388550016774 54.26109062883666
109 GOTERM_BP_FAT GO:0015931~nucleobase, nucleoside, nucleotide and nucleic acid transport 8 0.154828720727695 0.04503759075321534 NXT1, TMEM48, SEH1L, RAN, SLC25A19, MAGOHB, NUP107, THOC5 371 111 12596 2.446953692236711 1.0 0.9562265142592878 54.507495346987554
110 UP_SEQ_FEATURE repeat:WD 11 4 0.0774143603638475 0.04571546894171677 WDR3, CIRH1A, PWP2, GEMIN5 492 29 17662 4.9514998598261855 1.0 0.9983637943310794 53.65380658523322
111 GOTERM_BP_FAT GO:0046039~GTP metabolic process 3 0.05806077027288562 0.04675808659864336 RHOQ, NME7, GCH1 371 12 12596 8.487870619946092 1.0 0.9566759251952713 55.88819113998365
112 GOTERM_BP_FAT GO:0014068~positive regulation of phosphoinositide 3-kinase cascade 3 0.05806077027288562 0.04675808659864336 ERBB3, ERBB2, CAT 371 12 12596 8.487870619946092 1.0 0.9566759251952713 55.88819113998365
113 UP_SEQ_FEATURE repeat:Solcar 3 5 0.09676795045480936 0.0468155769242892 SLC25A32, SLC25A25, SLC25A33, SLC25A19, SLC25A15 492 49 17662 3.6630993860959014 1.0 0.99746084574398 54.52411115288388
114 GOTERM_BP_FAT GO:0007005~mitochondrion organization 9 0.17418231081865687 0.04724248391595082 TRNT1, PPIF, SSBP1, TIMM17A, BCS1L, BCL2L1, PMAIP1, MYC, C10ORF2 371 136 12596 2.246789281750436 1.0 0.9534216927295497 56.26974282171218
115 GOTERM_BP_FAT GO:0055082~cellular chemical homeostasis 18 0.34836462163731374 0.04878467781672101 ENPP1, WFS1, ERBB2, BCL2L1, NPY1R, SLC9A3R1, CXCL12, TMPRSS3, MBP, S1PR3, ADM, PLLP, STC1, PMP22, EIF2B2, JPH1, MYC, CLN6 371 373 12596 1.6384093421879855 1.0 0.9534411496776118 57.46391393973006
116 UP_SEQ_FEATURE repeat:WD 10 4 0.0774143603638475 0.04978193377702378 WDR3, CIRH1A, PWP2, GEMIN5 492 30 17662 4.786449864498645 1.0 0.9970737588415883 56.79495701096749
117 GOTERM_BP_FAT GO:0030856~regulation of epithelial cell differentiation 4 0.0774143603638475 0.0522879302908833 CDKN2B, BTG1, AQP3, IL20 371 29 12596 4.682963100659913 1.0 0.9588440073519989 60.063498147770765
118 GOTERM_BP_FAT GO:0006457~protein folding 10 0.19353590090961872 0.0528856348361937 BAG5, PPIF, CCT4, WFS1, FKBP4, BAG2, CCT2, CCT3, DNAJC1, HSPA9 371 164 12596 2.070212346328315 1.0 0.9562843851008211 60.49180245864469
119 UP_SEQ_FEATURE repeat:WD 7 9 0.17418231081865687 0.053101089388041534 WDR75, UTP15, WDR12, WDR3, BOP1, CIRH1A, PRPF4, PWP2, GEMIN5 492 147 17662 2.197859631657541 1.0 0.9968308486320917 59.20947204349296
120 SP_PIR_KEYWORDS neuropathy 4 0.0774143603638475 0.05374407002394571 LITAF, HSPB8, PMP22, C10ORF2 492 31 17699 4.641751901389982 0.9999999998372524 0.7774465635003579 53.82546712163369
121 GOTERM_BP_FAT GO:0014066~regulation of phosphoinositide 3-kinase cascade 3 0.05806077027288562 0.054209679484001 ERBB3, ERBB2, CAT 371 13 12596 7.834957495334855 1.0 0.9556750567963634 61.42523754858503
122 UP_SEQ_FEATURE transit peptide:Mitochondrion 20 0.38707180181923745 0.05463043281980444 MRPS17, SSBP1, MRPS12, PNPT1, PTRH2, C10ORF2, TRNT1, PPIF, CHCHD10, MRPL15, PPM1K, NARS2, MRPL16, MRPL36, FDX1L, ABAT, NLN, PMPCB, HMGCL, HSPA9 492 458 17662 1.5676145844427876 1.0 0.9959196138148659 60.27881043540509
123 UP_SEQ_FEATURE region of interest:Negative regulatory domain 2 0.03870718018192375 0.05482829399649009 MYBL1, MYB 492 2 17662 35.898373983739845 1.0 0.9942233092949896 60.41521821253259
124 UP_SEQ_FEATURE region of interest:Transcriptional activation domain 2 0.03870718018192375 0.05482829399649009 MYBL1, MYB 492 2 17662 35.898373983739845 1.0 0.9942233092949896 60.41521821253259
125 GOTERM_MF_FAT GO:0004766~spermidine synthase activity 2 0.03870718018192375 0.05486693094586338 SRM, SMS 336 2 12042 35.83928571428571 0.9999999999999998 0.9940658261872577 56.83180140922255
126 GOTERM_CC_FAT GO:0000313~organellar ribosome 5 0.09676795045480936 0.055729668096379255 MRPS17, MRPL3, MRPS12, MRPL16, MRPL36 355 48 11759 3.450410798122066 0.999999989862598 0.5837733903480565 53.89159028328383
127 GOTERM_CC_FAT GO:0005761~mitochondrial ribosome 5 0.09676795045480936 0.055729668096379255 MRPS17, MRPL3, MRPS12, MRPL16, MRPL36 355 48 11759 3.450410798122066 0.999999989862598 0.5837733903480565 53.89159028328383
128 INTERPRO IPR013878:Mo25-like 2 0.03870718018192375 0.055860424220444224 CAB39L, CAB39 438 2 15425 35.21689497716895 1.0 0.9802857345861472 59.116053308789226
129 INTERPRO IPR012642:Transcriptional regulator, Wos2-domain 2 0.03870718018192375 0.055860424220444224 MYBL1, MYB 438 2 15425 35.21689497716895 1.0 0.9802857345861472 59.116053308789226
130 INTERPRO IPR001045:Spermine synthase 2 0.03870718018192375 0.055860424220444224 SRM, SMS 438 2 15425 35.21689497716895 1.0 0.9802857345861472 59.116053308789226
131 GOTERM_MF_FAT GO:0004527~exonuclease activity 5 0.09676795045480936 0.05611189736532276 EXOSC9, ENPP1, PNPT1, EXOSC2, FEN1 336 52 12042 3.4460851648351647 0.9999999999999999 0.9898566665168013 57.67061923808645
132 UP_SEQ_FEATURE repeat:Solcar 1 5 0.09676795045480936 0.05612099897451779 SLC25A32, SLC25A25, SLC25A33, SLC25A19, SLC25A15 492 52 17662 3.4517667292057537 1.0 0.9929100604639097 61.295655155494956
133 UP_SEQ_FEATURE repeat:Solcar 2 5 0.09676795045480936 0.05612099897451779 SLC25A32, SLC25A25, SLC25A33, SLC25A19, SLC25A15 492 52 17662 3.4517667292057537 1.0 0.9929100604639097 61.295655155494956
134 GOTERM_CC_FAT GO:0030684~preribosome 3 0.05806077027288562 0.05663370272548011 WDR12, WDR3, BOP1 355 13 11759 7.643986998916576 0.999999992545913 0.5728667457428733 54.4840134596434
135 GOTERM_BP_FAT GO:0048545~response to steroid hormone stimulus 11 0.2128894910005806 0.0570974150695088 SOCS2, ERBB2, MAP1B, ARNT2, NPY1R, GAL, UGT1A1, TIMP3, UGT1A6, KRT19, ADM, UGT1A3, IDH1 371 192 12596 1.9451370170709792 1.0 0.9589622151130615 63.38952366070401
136 GOTERM_BP_FAT GO:0050657~nucleic acid transport 7 0.1354751306367331 0.060722832697936706 NXT1, TMEM48, SEH1L, RAN, MAGOHB, NUP107, THOC5 371 95 12596 2.501688182720953 1.0 0.9634102315227472 65.7223827843195
137 GOTERM_BP_FAT GO:0051236~establishment of RNA localization 7 0.1354751306367331 0.060722832697936706 NXT1, TMEM48, SEH1L, RAN, MAGOHB, NUP107, THOC5 371 95 12596 2.501688182720953 1.0 0.9634102315227472 65.7223827843195
138 GOTERM_BP_FAT GO:0050658~RNA transport 7 0.1354751306367331 0.060722832697936706 NXT1, TMEM48, SEH1L, RAN, MAGOHB, NUP107, THOC5 371 95 12596 2.501688182720953 1.0 0.9634102315227472 65.7223827843195
139 KEGG_PATHWAY hsa00053:Ascorbate and aldarate metabolism 3 0.05806077027288562 0.061403593371700135 UGT1A6, UGT1A3, UGDH, UGT2B15, UGT1A1 139 14 4719 7.274922918807811 0.999904078153189 0.9010355118192759 52.914253770947376
140 PIR_SUPERFAMILY PIRSF009316:hypothetical protein, Saccharomyces cerevisiae YKL189w type 2 0.03870718018192375 0.06188531696403608 CAB39L, CAB39 214 2 6776 31.663551401869157 0.9999999043354221 0.9954264820640341 56.45867103764558
141 PIR_SUPERFAMILY PIRSF000502:spermidine synthase/putrescine N-methyltransferase 2 0.03870718018192375 0.06188531696403608 SRM, SMS 214 2 6776 31.663551401869157 0.9999999043354221 0.9954264820640341 56.45867103764558
142 GOTERM_BP_FAT GO:0046112~nucleobase biosynthetic process 3 0.05806077027288562 0.06204614993559089 UMPS, PAICS, GART 371 14 12596 7.275317674239507 1.0 0.9627840541817946 66.53847565709756
143 GOTERM_BP_FAT GO:0060322~head development 3 0.05806077027288562 0.06204614993559089 LHX1, ARID5B, TIPARP 371 14 12596 7.275317674239507 1.0 0.9627840541817946 66.53847565709756
144 GOTERM_BP_FAT GO:0006268~DNA unwinding during replication 3 0.05806077027288562 0.06204614993559089 MCM2, C10ORF2, MCM6 371 14 12596 7.275317674239507 1.0 0.9627840541817946 66.53847565709756
145 GOTERM_BP_FAT GO:0045604~regulation of epidermal cell differentiation 3 0.05806077027288562 0.06204614993559089 MAFF, AQP3, IL20 371 14 12596 7.275317674239507 1.0 0.9627840541817946 66.53847565709756
146 INTERPRO IPR018108:Mitochondrial substrate/solute carrier 5 0.09676795045480936 0.06279027244732116 SLC25A32, SLC25A25, SLC25A33, SLC25A19, SLC25A15 438 53 15425 3.3223485827517876 1.0 0.9836451083563185 63.544037165105735
147 GOTERM_BP_FAT GO:0008033~tRNA processing 6 0.11612154054577124 0.06319872683298486 TRNT1, PUS1, METTL1, TSEN2, PUS7, DUS3L 371 73 12596 2.790532806557619 1.0 0.9618383191076789 67.2343332302167
148 GOTERM_BP_FAT GO:0046942~carboxylic acid transport 9 0.17418231081865687 0.06406301053954172 SLC1A4, SLC16A1, SLC25A32, SLC16A6, SLC7A1, SLC3A2, SLC7A5, SLC25A15, PDZK1 371 145 12596 2.1073333952969606 1.0 0.9603305090582193 67.74717307401498
149 SMART SM00253:SOCS 4 0.0774143603638475 0.06477646619034536 ASB9, SOCS2, WSB2, ASB13 217 37 8614 4.291443517249969 0.9999928873646389 0.9483574550566816 56.07042877800301
150 KEGG_PATHWAY hsa04110:Cell cycle 8 0.154828720727695 0.06516659524413596 CDC7, RBL2, CDKN2B, MCM2, GADD45B, MYC, ORC1L, MCM6 139 122 4719 2.226205920509494 0.9999466423701728 0.8602218442789262 55.109678145764605
151 GOTERM_CC_FAT GO:0042645~mitochondrial nucleoid 4 0.0774143603638475 0.06537416493633505 SSBP1, POLDIP2, C10ORF2, HSPA9 355 31 11759 4.274057246706043 0.999999999624398 0.6107706672072257 59.85921421497893
152 GOTERM_CC_FAT GO:0009295~nucleoid 4 0.0774143603638475 0.06537416493633505 SSBP1, POLDIP2, C10ORF2, HSPA9 355 31 11759 4.274057246706043 0.999999999624398 0.6107706672072257 59.85921421497893
153 GOTERM_BP_FAT GO:0019228~regulation of action potential in neuron 5 0.09676795045480936 0.06589836529186781 ERBB2, PLLP, PMP22, EIF2B2, MBP 371 52 12596 3.2645656230561895 1.0 0.9608275144962635 68.81126056800635
154 INTERPRO IPR002423:Chaperonin Cpn60/TCP-1 3 0.05806077027288562 0.06593423657955465 CCT4, CCT2, CCT3 438 15 15425 7.043378995433789 1.0 0.9823662256179122 65.40122447652179
155 GOTERM_BP_FAT GO:0007169~transmembrane receptor protein tyrosine kinase signaling pathway 12 0.23224308109154249 0.06597499135804756 CD3EAP, RET, SOCS2, ERBB3, EFNA1, ERBB2, ARID5B, TIPARP, RAF1, RHOQ, AREG, PIK3R3 371 224 12596 1.8188294185598768 1.0 0.9577675024388841 68.85495923603811
156 GOTERM_BP_FAT GO:0015849~organic acid transport 9 0.17418231081865687 0.06613507279717493 SLC1A4, SLC16A1, SLC25A32, SLC16A6, SLC7A1, SLC3A2, SLC7A5, SLC25A15, PDZK1 371 146 12596 2.0928996049182143 1.0 0.9548143864375629 68.94606528415143
157 PIR_SUPERFAMILY PIRSF002458:ADP,ATP carrier protein 4 0.0774143603638475 0.06675925357208444 SLC25A32, SLC25A33, SLC25A19, SLC25A15 214 30 6776 4.221806853582554 0.9999999743903191 0.9873496936784786 59.31279519623354
158 GOTERM_BP_FAT GO:0006403~RNA localization 7 0.1354751306367331 0.06849033509943744 NXT1, TMEM48, SEH1L, RAN, MAGOHB, NUP107, THOC5 371 98 12596 2.425105891413169 1.0 0.9565694912684699 70.25783131652807
159 SMART SM00462:PTB 4 0.0774143603638475 0.06908008238582963 TNS3, DAB2, RABGAP1, APPL2 217 38 8614 4.178510793111812 0.9999968560106534 0.9206592661398919 58.489972201007134
160 KEGG_PATHWAY hsa00040:Pentose and glucuronate interconversions 3 0.05806077027288562 0.06952691394035429 UGT1A6, UGT1A3, UGDH, UGT2B15, UGT1A1 139 15 4719 6.789928057553957 0.9999730376905446 0.8268352401946198 57.536117566223055
161 UP_SEQ_FEATURE domain:Helix-loop-helix motif 7 0.1354751306367331 0.06998553251247153 ID1, MITF, ARNT2, MLXIP, ID3, MYC, MXD4 492 104 17662 2.4162367104440277 1.0 0.9971240101337505 69.65125257349614
162 SP_PIR_KEYWORDS Growth factor binding 3 0.05806077027288562 0.07133013602789481 FGFBP2, IGFBP3, IGFBP4 492 16 17699 6.745045731707317 0.9999999999999228 0.8484819085494514 64.48297475304766
163 INTERPRO IPR001092:Basic helix-loop-helix dimerisation region bHLH 7 0.1354751306367331 0.07236506299606205 ID1, MITF, ARNT2, MLXIP, ID3, MYC, MXD4 438 103 15425 2.3933812120406084 1.0 0.9845321883108719 68.92766362967458
164 GOTERM_MF_FAT GO:0042802~identical protein binding 25 0.48383975227404685 0.07278111382517277 PYCRL, KYNU, NRBP1, CLDN4, ENPP1, ERBB3, ERBB2, BCL2L1, GCH1, GPD1L, RILPL2, CAT, CARS, MOCS2, KIAA1804, TPD52L1, ABCG1, FOXP1, MCM6, GLA, HSPB8, PRDM6, ABAT, PAICS, CLN6 336 630 12042 1.4221938775510203 1.0 0.9952039870773707 67.53295446202809
165 SMART SM00261:FU 3 0.05806077027288562 0.07361246722646513 CRELD2, ERBB3, ERBB2 217 18 8614 6.615975422427035 0.9999986747182829 0.8951943487137284 60.90529630641354
166 GOTERM_CC_FAT GO:0030529~ribonucleoprotein complex 22 0.4257789820011612 0.07514913475889104 MRPS17, MRPL3, MRPS23, UTP18, MRPS12, SNRPD3, ILF3, BOP1, SRPRB, PRPF4, NCL, MRPS2, PA2G4, MRPL15, EIF2S1, MRPL16, MRPL36, WDR3, WDR12, UTP20, GEMIN4, GEMIN5 355 498 11759 1.4633067481192374 0.9999999999871466 0.648270265852607 65.17107230957828
167 SP_PIR_KEYWORDS nucleotide binding 7 0.1354751306367331 0.07732721692879588 ABCE1, RAB31, RAB5B, MYO1B, DDX21, GEM, ABCA3 492 107 17699 2.353411594863612 0.9999999999999946 0.8550744222477437 67.56016401440917
168 GOTERM_MF_FAT GO:0004540~ribonuclease activity 5 0.09676795045480936 0.07747232025755106 EXOSC9, PNPT1, EXOSC2, TSEN2, FEN1 336 58 12042 3.089593596059113 1.0 0.9940749747878824 69.89429747397247
169 GOTERM_MF_FAT GO:0015171~amino acid transmembrane transporter activity 5 0.09676795045480936 0.07747232025755106 SLC1A4, SLC7A1, SLC3A2, SLC7A5, SLC25A15 336 58 12042 3.089593596059113 1.0 0.9940749747878824 69.89429747397247
170 GOTERM_BP_FAT GO:0048511~rhythmic process 8 0.154828720727695 0.07787079515695292 PGR, EGR3, ERBB3, ERBB2, HEBP1, BCL2L1, EIF2B2, NRIP1 371 126 12596 2.1556496812561505 1.0 0.9698807106029829 74.98235652348382
171 GOTERM_BP_FAT GO:0006270~DNA replication initiation 3 0.05806077027288562 0.07875946073022135 MCM2, ORC1L, MCM6 371 16 12596 6.365902964959569 1.0 0.96874216425548 75.39124367707407
172 UP_SEQ_FEATURE repeat:WD 13 3 0.05806077027288562 0.07968846271273608 WDR3, PWP2, GEMIN5 492 17 17662 6.335007173601149 1.0 0.9982092333474429 74.45629964447778
173 KEGG_PATHWAY hsa03018:RNA degradation 5 0.09676795045480936 0.08001879542354977 EXOSC9, PNPT1, EXOSC2, HSPA9, ENO1 139 56 4719 3.0312178828365877 0.999994850946711 0.8243967765339105 62.890614032419734
174 UP_SEQ_FEATURE region of interest:Phosphate binding 2 0.03870718018192375 0.08110685048905872 PTP4A1, PTP4A2 492 3 17662 23.932249322493227 1.0 0.9977649835029264 75.09565940321671
175 UP_SEQ_FEATURE region of interest:Sufficient for nucleolar localization 2 0.03870718018192375 0.08110685048905872 WDR12, BOP1 492 3 17662 23.932249322493227 1.0 0.9977649835029264 75.09565940321671
176 GOTERM_MF_FAT GO:0004045~aminoacyl-tRNA hydrolase activity 2 0.03870718018192375 0.08116423809997529 PTRH1, PTRH2 336 3 12042 23.892857142857142 1.0 0.9925100030875497 71.63891516034236
177 UP_SEQ_FEATURE repeat:WD 8 5 0.09676795045480936 0.0813686616958427 WDR75, WDR3, CIRH1A, PWP2, GEMIN5 492 59 17662 3.0422350833677827 1.0 0.9970260534332551 75.2120191686928
178 GOTERM_CC_FAT GO:0005643~nuclear pore 6 0.11612154054577124 0.08215754658164755 NXT1, TMEM48, CSE1L, SEH1L, RAN, NUP107 355 77 11759 2.5810865191146877 0.9999999999988817 0.6673841532820154 68.57037166878669
179 SP_PIR_KEYWORDS dna-directed rna polymerase 4 0.0774143603638475 0.08241747335051093 CD3EAP, POLR3H, POLR3K, POLR2D 492 37 17699 3.8890353768402552 0.9999999999999994 0.8576722047915892 69.97584260028755
180 GOTERM_BP_FAT GO:0034097~response to cytokine stimulus 6 0.11612154054577124 0.08255898120304828 IL1R1, KYNU, CDKN2B, OSMR, BCL2L1, GCH1 371 79 12596 2.5785936060595724 1.0 0.9715880187663408 77.06954122714804
181 INTERPRO IPR015395:C-myb, C-terminal 2 0.03870718018192375 0.08261196377777202 MYBL1, MYB 438 3 15425 23.4779299847793 1.0 0.9889350690136276 73.85973075729541
182 UP_SEQ_FEATURE domain:SOCS box 4 0.0774143603638475 0.08281805338090571 ASB9, SOCS2, WSB2, ASB13 492 37 17662 3.8809052955394425 1.0 0.9964610017380934 75.84700617061156
183 GOTERM_MF_FAT GO:0015179~L-amino acid transmembrane transporter activity 4 0.0774143603638475 0.08286121045583936 SLC1A4, SLC7A1, SLC7A5, SLC25A15 336 37 12042 3.874517374517374 1.0 0.9897892349819918 72.40876464020239
184 GOTERM_MF_FAT GO:0001948~glycoprotein binding 4 0.0774143603638475 0.08286121045583936 ERBB2, GPC6, IGF2R, TGFA 336 37 12042 3.874517374517374 1.0 0.9897892349819918 72.40876464020239
185 SP_PIR_KEYWORDS disease mutation 54 1.045093864911941 0.08330897317694867 KYNU, OSMR, WFS1, MITF, SLC26A2, SLC16A1, CDKN2B, SLC2A1, TGFBI, VPS13B, CIRH1A, EIF2B2, HMGCL, RET, OPTN, SLC9A3R1, FLNB, UGT1A1, C10ORF2, UMPS, SGCG, CFL2, HSPB8, DOK7, CTSD, ABAT, MCC, PMP22, CLN6, SLC2A10, LITAF, ENPP1, PUS1, SOX3, NDP, NR3C1, TIMP3, SLC19A2, ABCA3, PDSS1, GCH1, GPD1L, UGT1A6, UGT1A3, ABCA12, MOCS2, RFX5, RAF1, BCS1L, ANKH, TMPRSS3, GLA, SLC25A19, CYP2R1, TJP2, SLC25A15 492 1581 17699 1.2286990327208775 0.9999999999999997 0.845549895453167 70.38132511196707
186 GOTERM_CC_FAT GO:0005635~nuclear envelope 11 0.2128894910005806 0.0845990599564739 NXT1, DHRS2, TMEM48, CSE1L, PTGES, SEH1L, RAN, IGF2R, CACYBP, NUP107, TMEM38B 355 202 11759 1.8037791103053968 0.9999999999995244 0.6642253759702137 69.6805259788722
187 GOTERM_BP_FAT GO:0050801~ion homeostasis 18 0.34836462163731374 0.0849221702964138 ENPP1, WFS1, ERBB2, BCL2L1, NPY1R, SLC9A3R1, CXCL12, TMPRSS3, MBP, S1PR3, ADM, PLLP, STC1, PMP22, EIF2B2, JPH1, MYC, CLN6 371 401 12596 1.5240066948531636 1.0 0.9723878349316564 78.05839166978241
188 GOTERM_BP_FAT GO:0000463~maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2 0.03870718018192375 0.08556658466825445 WDR12, BOP1 371 3 12596 22.634321653189577 1.0 0.9710625133989828 78.32098961075718
189 GOTERM_BP_FAT GO:0006184~GTP catabolic process 2 0.03870718018192375 0.08556658466825445 RHOQ, GCH1 371 3 12596 22.634321653189577 1.0 0.9710625133989828 78.32098961075718
190 GOTERM_BP_FAT GO:0000470~maturation of LSU-rRNA 2 0.03870718018192375 0.08556658466825445 WDR12, BOP1 371 3 12596 22.634321653189577 1.0 0.9710625133989828 78.32098961075718
191 GOTERM_BP_FAT GO:0034754~cellular hormone metabolic process 5 0.09676795045480936 0.08602239802498166 UGT1A6, DHRS2, UGT1A3, ADM, NR3C1, COMT, UGT1A1 371 57 12596 2.978200217524945 1.0 0.9694888270861228 78.50494315144196
192 INTERPRO IPR001496:SOCS protein, C-terminal 4 0.0774143603638475 0.08649211160480948 ASB9, SOCS2, WSB2, ASB13 438 37 15425 3.8072318894236696 1.0 0.9884705949611564 75.52814456720257
193 GOTERM_CC_FAT GO:0016323~basolateral plasma membrane 11 0.2128894910005806 0.086971538368316 TNS3, SLC12A2, ENPP1, S100A7, ERBB3, ANK3, ERBB2, SLC2A1, FAIM3, NEDD9, AQP3 355 203 11759 1.794893498924582 0.9999999999997933 0.660997873483784 70.72440574403322
194 GOTERM_CC_FAT GO:0070545~PeBoW complex 2 0.03870718018192375 0.0876294505858011 WDR12, BOP1 355 3 11759 22.082629107981223 0.9999999999998359 0.6505444648168908 71.00793284839992
195 GOTERM_BP_FAT GO:0007517~muscle organ development 11 0.2128894910005806 0.08799882602610719 EGR3, SGCG, TBX2, ERBB3, SVIL, ERBB2, ARID5B, TIPARP, JPH1, FLNB, FOXP1 371 209 12596 1.7869201305149667 1.0 0.969868204715018 79.28570604552564
196 GOTERM_BP_FAT GO:0007422~peripheral nervous system development 4 0.0774143603638475 0.08813958897469344 EGR3, ERBB3, ERBB2, PMP22 371 36 12596 3.772386942198263 1.0 0.9679115087534728 79.34028163773749
197 GOTERM_MF_FAT GO:0035258~steroid hormone receptor binding 4 0.0774143603638475 0.08819510377079641 RAN, FKBP4, PHB2, NRIP1 336 38 12042 3.772556390977443 1.0 0.9890785941669246 74.70350872405274
198 GOTERM_BP_FAT GO:0043627~response to estrogen stimulus 7 0.1354751306367331 0.08874702195412824 KRT19, SOCS2, ARNT2, MAP1B, NPY1R, GAL, TIMP3 371 105 12596 2.263432165318958 1.0 0.966542495755039 79.57424234250863
199 GOTERM_BP_FAT GO:0030518~steroid hormone receptor signaling pathway 5 0.09676795045480936 0.09036803406905028 PGR, KLF9, RAN, NR3C1, NRIP1 371 58 12596 2.9268519379124456 1.0 0.9665344069647238 80.18644540444318
200 INTERPRO IPR006212:Furin-like repeat 3 0.05806077027288562 0.09093328552022989 CRELD2, ERBB3, ERBB2 438 18 15425 5.869482496194824 1.0 0.9883882840953013 77.3153251535876
201 PIR_SUPERFAMILY PIRSF016102:prenylated protein tyrosine phosphatase 2 0.03870718018192375 0.09138316572286286 PTP4A1, PTP4A2 214 3 6776 21.109034267912772 0.999999999970465 0.9921644874303042 71.27156976103554
202 GOTERM_CC_FAT GO:0005792~microsome 12 0.23224308109154249 0.09200317680660346 COMT, UGT1A1, UGT1A6, PPP1R3C, UGT1A3, DGAT2, PTGES, ELOVL2, CYP2R1, UGT2B15, JPH1, DNAJC1, GRB14, SSR3 355 232 11759 1.7133074307916463 0.9999999999999649 0.6564128732071504 72.82910649291317
203 INTERPRO IPR006020:Phosphotyrosine interaction region 4 0.0774143603638475 0.09202508959029958 TNS3, DAB2, RABGAP1, APPL2 438 38 15425 3.7070415765440994 1.0 0.9862444216872271 77.7355769120728
204 INTERPRO IPR013785:Aldolase-type TIM barrel 4 0.0774143603638475 0.09202508959029958 UMPS, GLA, HMGCL, DUS3L 438 38 15425 3.7070415765440994 1.0 0.9862444216872271 77.7355769120728
205 BIOCARTA h_mta3Pathway:Downregulated of MTA-3 in ER-negative Breast Tumors 3 0.05806077027288562 0.09227110276436244 GREB1, CTSD, PDZK1 50 15 1418 5.672000000000001 0.9999241939608462 0.9912933336371593 65.7140045912704
206 KEGG_PATHWAY hsa00500:Starch and sucrose metabolism 4 0.0774143603638475 0.09251322629649751 UGT1A6, UGT1A3, ENPP1, UGDH, UGT2B15, UGT1A1 139 37 4719 3.6702313824615986 0.9999993006664015 0.8299465100568787 68.45735319208228
207 SP_PIR_KEYWORDS Aminoacyl-tRNA synthetase 4 0.0774143603638475 0.09317051472436788 IARS, CARS, NARS2, HARS 492 39 17699 3.689597665207422 1.0 0.8640050111674227 74.54002603885561
208 OMIM_DISEASE Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder 2 0.03870718018192375 0.09344551670063377 ANK3, RASGRP1 98 3 3016 20.517006802721088 0.9999999919676449 0.9999999919676449 70.45632688134472
209 GOTERM_BP_FAT GO:0001667~ameboidal cell migration 4 0.0774143603638475 0.0939274291387453 RET, ARID5B, CAP1, CXCL12 371 37 12596 3.670430538355067 1.0 0.9689559510216287 81.47063422072405
210 GOTERM_BP_FAT GO:0051789~response to protein stimulus 7 0.1354751306367331 0.09507567635557805 ID1, KLF10, MAP1B, CREB3L4, ID3, BCL2L1, NR3C1 371 107 12596 2.221125022041968 1.0 0.9683508539649704 81.86790363084953
211 GOTERM_BP_FAT GO:0042981~regulation of apoptosis 31 0.5999612928198181 0.09641845525631683 ERBB3, WFS1, ERBB2, MITF, ARNT2, BCL2L1, NR3C1, PMAIP1, TIMP3, GCH1, BOK, CAT, MYC, HSPA9, DEPDC6, SOCS2, SGK3, KLF10, GAL, BCL2L11, PPIF, DHRS2, BTG2, BTG1, EEF1E1, IGF2R, FAIM3, BIK, ID3, IGFBP3, TP53INP1 371 797 12596 1.3205720914345236 1.0 0.967992713147463 82.32230304059792
212 GOTERM_BP_FAT GO:0032392~DNA geometric change 3 0.05806077027288562 0.09668274856575734 MCM2, C10ORF2, MCM6 371 18 12596 5.658580413297395 1.0 0.9663305970280236 82.41046827412919
213 GOTERM_BP_FAT GO:0032508~DNA duplex unwinding 3 0.05806077027288562 0.09668274856575734 MCM2, C10ORF2, MCM6 371 18 12596 5.658580413297395 1.0 0.9663305970280236 82.41046827412919
214 GOTERM_BP_FAT GO:0006611~protein export from nucleus 3 0.05806077027288562 0.09668274856575734 NXT1, RAN, HSPA9 371 18 12596 5.658580413297395 1.0 0.9663305970280236 82.41046827412919
215 GOTERM_BP_FAT GO:0007049~cell cycle 30 0.5806077027288562 0.09920673440710708 PPP6C, RABGAP1, TIPIN, NEDD9, CCNG1, CCNG2, NUMA1, CDKN2B, SEH1L, CDC123, HBP1, MYC, CDC7, RBL2, RAN, TPD52L1, ILF3, MCM2, TET2, APPL2, TACC1, MCM6, PA2G4, NOLC1, PTP4A1, RRS1, SIAH2, CHAF1A, DSCC1, TP53INP1 371 769 12596 1.3245051682620688 1.0 0.9674313661018827 83.23184022499768
216 GOTERM_BP_FAT GO:0051168~nuclear export 5 0.09676795045480936 0.0993673243744065 NXT1, RAN, NUP107, THOC5, HSPA9 371 60 12596 2.829290206648697 1.0 0.9656828298184813 83.28285905033889
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