Attachment '24hr_DAVID_output.txt'
Download 1 Category Term Count % PValue Genes List Total Pop Hits Pop Total Fold Enrichment Bonferroni Benjamini FDR
2 GOTERM_BP_FAT GO:0009725~response to hormone stimulus 22 0.4569055036344756 3.8270976415914835E-4 ERBB4, SOCS2, ERBB3, ARNT2, ADIPOR2, ESR1, FHL2, AURKA, NPY1R, GAL, ABCG1, CTNNB1, GSTM3, GOT1, BTG2, ADM, GATA3, JAK2, THBS1, EIF2B3, ABCC5, MB 317 367 12596 2.3819355504173148 0.5349293886055572 0.5349293886055572 0.6559659023439135
3 GOTERM_CC_FAT GO:0031974~membrane-enclosed lumen 70 1.453790238836968 5.000257377687546E-4 LYAR, SNRPD3, ARNT2, PDLIM3, MKI67IP, CTNNB1, WDR75, CDCA8, DNAJB11, LRRC59, CAT, TOP2B, IMP4, MYC, MYO6, MRPL3, RBL2, EMG1, TLE1, DARS2, PRPF4, TIMM8A, COQ3, C1QBP, NAV2, PPM1K, ALDH1B1, TXNDC5, NLE1, SNRPC, ANAPC7, RUVBL1, MRPS17, POLR2F, FKBP4, YPEL2, MRPS12, YPEL3, NOC3L, CLU, PNPT1, BOP1, MYBL1, CHCHD4, TCF7L2, CORO2A, MRPL16, NPM3, WDR12, NAT10, GEMIN6, THBS1, RBM28, BUB3, ETFA, GEMIN5, POLR3H, PHB, MRPS25, PNO1, NXF1, APPL2, PPIF, CCNB1, DDX56, PLK1, WDR4, SUMF2, JAK2, RPP40 303 1832 11759 1.4828606223067722 0.1538430061259508 0.1538430061259508 0.6769837929745504
4 GOTERM_BP_FAT GO:0009719~response to endogenous stimulus 23 0.47767393561786087 5.639954975190645E-4 ERBB4, SOCS2, ERBB3, ARNT2, ADIPOR2, ESR1, FHL2, AURKA, NPY1R, GAL, ABCG1, CTNNB1, GSTM3, GOT1, BTG2, ADM, GATA3, VKORC1, JAK2, THBS1, EIF2B3, ABCC5, MB 317 405 12596 2.256556451298828 0.6764200987586237 0.431159160009255 0.9652737946542866
5 GOTERM_CC_FAT GO:0000267~cell fraction 46 0.9553478712357217 5.841661947821258E-4 RAP1GAP, HAX1, SLC20A2, CNP, SLC26A2, GCLM, FDFT1, CTNNB1, IARS, GSTM3, PPP1R3C, SLC16A1, GOT1, ANK3, SLC2A1, LRRC59, PXMP4, GPX3, CLEC2D, VKORC1, ATP8B1, GLO1, SCARB2, SNAP23, SLC1A1, DNAJC1, SLC12A2, PSD3, NPR3, PKIA, PPIF, LAMP2, UGT2B17, BLMH, EPS8, DGAT2, ADM, NME1, VAMP8, SPCS3, FARSB, SYTL2, JAK2, UGT2B15, ABCC5, GRB14 303 1066 11759 1.674666716202577 0.1773039943859961 0.09297408768326587 0.7904831827348913
6 GOTERM_CC_FAT GO:0005739~mitochondrion 45 0.9345794392523363 9.069640538483584E-4 MRPS17, ECH1, HAX1, TIMM17A, MRPS12, PNPT1, CLU, CTSA, ATP5G1, CHCHD4, NDUFAF2, ACSF2, AUH, AGXT2L2, MTHFD1, TSC22D3, MRPL15, MRPL14, MRPL16, LRRC59, CAT, PTS, WWOX, ETFA, MRPL3, MRPS25, PHB, MRPS6, C20ORF7, DARS2, TIMM8A, PPIF, COQ3, PRELID1, DHRS2, NNT, C1QBP, ALDH1B1, PTCD3, PPM1K, GRN, C3ORF31, CTSD, BIK, PDZK1 303 1057 11759 1.6522101595211556 0.2614477652187672 0.09608608467267632 1.2248004182918604
7 UP_SEQ_FEATURE transit peptide:Mitochondrion 23 0.47767393561786087 9.3420455269137E-4 MRPS17, ECH1, MRPS12, PNPT1, C20ORF7, DARS2, ATP5G1, NDUFAF2, ACSF2, AUH, PPIF, PRELID1, COQ3, NNT, MRPL15, C1QBP, PTCD3, MRPL14, ALDH1B1, PPM1K, C3ORF31, MRPL16, ETFA 406 458 17662 2.184621507088003 0.6608727458758088 0.6608727458758088 1.4928868392886763
8 GOTERM_BP_FAT GO:0051340~regulation of ligase activity 9 0.1869158878504673 9.41875622997757E-4 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7, GCLM, BUB3 317 81 12596 4.415001752541185 0.8481161102280331 0.4664555946627983 1.6070956592111219
9 SP_PIR_KEYWORDS mitochondrion 34 0.7061266874350987 9.905113115605674E-4 MRPS17, ECH1, HAX1, TIMM17A, MRPS12, PNPT1, CHCHD4, ATP5G1, ACSF2, NDUFAF2, AUH, AGXT2L2, TSC22D3, MRPL15, MRPL14, MRPL16, WWOX, ETFA, MRPL3, MRPS25, PHB, MRPS6, C20ORF7, DARS2, TIMM8A, PPIF, COQ3, PRELID1, NNT, C1QBP, PTCD3, ALDH1B1, PPM1K, C3ORF31 406 809 17699 1.8321165216438222 0.3305882168372871 0.3305882168372871 1.3752107205394437
10 GOTERM_BP_FAT GO:0010033~response to organic substance 33 0.6853582554517134 0.0011054320276629094 IL1R1, ERBB4, ERBB3, ARNT2, FHL2, AURKA, CTNNB1, GSTM3, GOT1, GATA3, VKORC1, CREB3L4, THBS1, EIF2B3, MYC, MB, HSP90AA1, SOCS2, ADIPOR2, ESR1, COLEC12, NPY1R, GAL, ABCG1, BTG2, ID2, ADM, EPS8, ID1, NME1, JAK2, ID3, ABCC5 317 717 12596 1.8288082573287754 0.8905280510574836 0.4247909471843292 1.8836764048979604
11 GOTERM_BP_FAT GO:0009968~negative regulation of signal transduction 15 0.3115264797507788 0.001112506916218545 DEPDC6, TWSG1, SOCS2, ERBB3, TLE1, PAWR, DDIT4, PEG10, DKK1, DDIT4L, THBS1, IGFBP3, WWOX, GRB14, IGFBP5 317 216 12596 2.7593760953382405 0.8920678427429971 0.3593362204511594 1.895623800353985
12 SP_PIR_KEYWORDS transit peptide 23 0.47767393561786087 0.0011788599867074683 MRPS17, ECH1, MRPS12, PNPT1, C20ORF7, DARS2, ATP5G1, NDUFAF2, ACSF2, AUH, PPIF, PRELID1, COQ3, NNT, MRPL15, C1QBP, PTCD3, MRPL14, ALDH1B1, PPM1K, C3ORF31, MRPL16, ETFA 406 467 17699 2.147007942954188 0.37980413058915086 0.21247484522026272 1.6347159503951159
13 GOTERM_BP_FAT GO:0010648~negative regulation of cell communication 16 0.3322949117341641 0.0012249793688022738 DEPDC6, TWSG1, SOCS2, ERBB3, TLE1, PAWR, ADORA1, DDIT4, PEG10, DKK1, DDIT4L, THBS1, IGFBP3, WWOX, GRB14, IGFBP5 317 243 12596 2.6162973348392207 0.9138323566227938 0.33540454144707676 2.08537258926651
14 SP_PIR_KEYWORDS acetylation 83 1.723779854620976 0.0013499181589024804 SAT1, S100A7, PITPNA, DTYMK, MKI67IP, ACSF2, MTHFD1, SFRS7, WDR75, NUDCD1, PRMT5, LRRC59, RANBP1, ARHGAP8, NQO1, TOP2B, RAB27B, MYC, EIF2B3, DEPDC6, HSP90AA1, EMG1, SLC3A2, DARS2, PRPF4, DCTN4, TIMM8A, SCCPDH, BLMH, NNT, C1QBP, VAMP8, NME1, EIF4A1, FARSB, NLE1, SERPINB1, SNRPC, RUVBL1, UBE2S, ECH1, PPME1, SRM, RAP1GAP, HAX1, ASS1, FKBP4, PNPT1, BOP1, MYBL1, GCLM, IARS, PSMF1, RPS26, PRR5, FAM107B, METTL1, WDR12, NPM3, GLO1, NAT10, SNAP23, RBM28, ARL6IP5, BUB3, GEMIN5, RAB2A, BOLA2, PHB, RRP15, PNO1, NXF1, PPIF, CCNB1, DDX56, PLEKHF2, CCT4, PSMD12, PTCD3, WDR4, GPATCH4, AHSA1, HIST1H3H, FABP5 406 2600 17699 1.3916417203486169 0.42136662067186137 0.166700423734367 1.8698489993387635
15 GOTERM_BP_FAT GO:0030858~positive regulation of epithelial cell differentiation 4 0.08307372793354102 0.0016463361351334203 BTG1, NME1, CTNNB1, IL20 317 10 12596 15.894006309148265 0.9629462482833842 0.37547841204860166 2.793161899081986
16 GOTERM_BP_FAT GO:0044092~negative regulation of molecular function 19 0.3946002076843198 0.001762974313374502 DEPDC6, NPY1R, NPR3, ADORA1, PKIA, PSMB5, PSMF1, PSMD12, ID2, GLA, ID1, PSMD3, JAK2, ID3, CAT, ANAPC7, NQO1, GADD45B, BUB3 317 331 12596 2.2808619325816997 0.9706675352084799 0.3566925665024364 2.9882358545410215
17 GOTERM_BP_FAT GO:0051439~regulation of ubiquitin-protein ligase activity during mitotic cell cycle 8 0.16614745586708204 0.001968572785221309 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7, BUB3 317 71 12596 4.477184875816413 0.9805717277753092 0.3546043706584716 3.3311958480087833
18 GOTERM_BP_FAT GO:0022402~cell cycle process 27 0.5607476635514018 0.0019739215379464712 AURKA, CEP55, TCF7L2, CCNG2, CTNNB1, PSMB5, PSMF1, CDCA8, CENPA, PSMD3, HBP1, RANBP1, THBS1, ZWILCH, DNAJC2, MYC, CDCA5, BUB3, TPD52L1, CCNB1, PSMD12, SPAG5, PLK1, ID4, RUVBL1, ANAPC7, TP53INP1 317 562 12596 1.9089776260987683 0.9807788602530355 0.3264374791799891 3.3401028742157224
19 GOTERM_CC_FAT GO:0043233~organelle lumen 66 1.3707165109034267 0.002149810811186392 LYAR, SNRPD3, ARNT2, PDLIM3, MKI67IP, CTNNB1, WDR75, CDCA8, DNAJB11, LRRC59, TOP2B, IMP4, MYC, MYO6, MRPL3, RBL2, EMG1, TLE1, DARS2, PRPF4, COQ3, C1QBP, NAV2, PPM1K, ALDH1B1, TXNDC5, NLE1, SNRPC, ANAPC7, RUVBL1, MRPS17, POLR2F, FKBP4, YPEL2, MRPS12, YPEL3, NOC3L, CLU, MYBL1, BOP1, TCF7L2, CORO2A, MRPL16, NPM3, WDR12, NAT10, GEMIN6, THBS1, RBM28, BUB3, ETFA, GEMIN5, POLR3H, PHB, MRPS25, PNO1, NXF1, APPL2, PPIF, CCNB1, DDX56, PLK1, WDR4, SUMF2, JAK2, RPP40 303 1797 11759 1.4253568929513987 0.5126680376368159 0.16448120454058235 2.880629487269115
20 GOTERM_CC_FAT GO:0005624~membrane fraction 35 0.726895119418484 0.0023057534852858348 RAP1GAP, SLC20A2, CNP, SLC26A2, CTNNB1, FDFT1, SLC16A1, PPP1R3C, ANK3, SLC2A1, PXMP4, LRRC59, CLEC2D, VKORC1, ATP8B1, SCARB2, SNAP23, SLC1A1, DNAJC1, SLC12A2, PSD3, NPR3, PPIF, LAMP2, UGT2B17, DGAT2, EPS8, NME1, VAMP8, SPCS3, JAK2, SYTL2, UGT2B15, GRB14, ABCC5 303 795 11759 1.7085538742553499 0.5374547488952536 0.1429012824268111 3.0865644580277296
21 GOTERM_BP_FAT GO:0051351~positive regulation of ligase activity 8 0.16614745586708204 0.0023115021584507386 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7, GCLM 317 73 12596 4.354522276478977 0.990229187044916 0.3434520838635913 3.900698744603648
22 GOTERM_BP_FAT GO:0000278~mitotic cell cycle 20 0.4153686396677051 0.002465810489574557 TPD52L1, AURKA, CEP55, CCNG2, PSMB5, CCNB1, PSMF1, CDCA8, PSMD12, PLK1, SPAG5, CENPA, PSMD3, ID4, ANAPC7, RUVBL1, ZWILCH, DNAJC2, CDCA5, BUB3 317 369 12596 2.1536593914835045 0.9928290075300813 0.3373285316858209 4.155926438468327
23 GOTERM_BP_FAT GO:0006979~response to oxidative stress 12 0.24922118380062305 0.002581598659241534 PSMB5, DHRS2, ERBB4, S100A7, CLU, GPX3, JAK2, SEPP1, CAT, NQO1, GCLM, MB 317 162 12596 2.9433345016941233 0.99431471182516 0.32812473554062904 4.347021948375707
24 GOTERM_BP_FAT GO:0008283~cell proliferation 22 0.4569055036344756 0.002836827505527982 ERBB4, DTYMK, BOP1, CXCL12, TCF7L2, APPL2, CTNNB1, ASCL1, ZFP36L2, DAB2, EPS8, PLK1, TACSTD2, PRMT5, TGFBI, WDR12, ID4, FOXC1, AREG, MYC, PDZK1, BUB3 317 430 12596 2.032954295356173 0.9965923005162634 0.33358120819490233 4.766982260073305
25 GOTERM_CC_FAT GO:0070013~intracellular organelle lumen 64 1.3291796469366564 0.0030978482733911928 LYAR, SNRPD3, ARNT2, PDLIM3, MKI67IP, CTNNB1, WDR75, CDCA8, DNAJB11, LRRC59, TOP2B, IMP4, MYC, MYO6, MRPL3, RBL2, EMG1, TLE1, DARS2, PRPF4, COQ3, C1QBP, NAV2, PPM1K, ALDH1B1, TXNDC5, NLE1, SNRPC, ANAPC7, RUVBL1, MRPS17, POLR2F, FKBP4, YPEL2, MRPS12, YPEL3, NOC3L, MYBL1, BOP1, TCF7L2, CORO2A, MRPL16, NPM3, WDR12, NAT10, GEMIN6, RBM28, BUB3, ETFA, GEMIN5, POLR3H, PHB, MRPS25, PNO1, NXF1, APPL2, PPIF, CCNB1, DDX56, PLK1, WDR4, SUMF2, JAK2, RPP40 303 1756 11759 1.4144357488140613 0.6452306020181184 0.15862224586932472 4.1263586354736255
26 SP_PIR_KEYWORDS nucleotide binding 9 0.1869158878504673 0.0031874840882492026 RAB2A, DDX17, MYO6, SRPR, MYO1B, DTYMK, EIF4A1, CNP, ABCC5 406 107 17699 3.6667510703927078 0.72555182928809 0.2762058225650045 4.363029377410188
27 GOTERM_BP_FAT GO:0007049~cell cycle 33 0.6853582554517134 0.003319001134522578 DTYMK, AURKA, CEP55, TCF7L2, CCNG2, CTNNB1, PSMB5, PSMF1, CDCA8, PRR5, CENPA, PSMD3, RANBP1, HBP1, THBS1, ARHGAP8, ZWILCH, DNAJC2, MYC, CDCA5, BUB3, RBL2, TPD52L1, APPL2, CCNB1, PSMD12, SPAG5, PLK1, PTP4A1, ID4, RUVBL1, ANAPC7, SIAH2, TP53INP1 317 769 12596 1.7051437197720831 0.998704738239561 0.35806581631766154 5.555628497193887
28 GOTERM_BP_FAT GO:0048545~response to steroid hormone stimulus 13 0.2699896157840083 0.003330705639931286 SOCS2, ERBB4, ARNT2, ESR1, AURKA, NPY1R, GAL, CTNNB1, GSTM3, GOT1, ADM, GATA3, THBS1 317 192 12596 2.6903916929547846 0.9987348057036339 0.34100089224246577 5.574695770894755
29 GOTERM_BP_FAT GO:0051438~regulation of ubiquitin-protein ligase activity 8 0.16614745586708204 0.003370724919750834 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7, BUB3 317 78 12596 4.07538623311494 0.9988324377167935 0.3278177157792257 5.639861959867865
30 GOTERM_CC_FAT GO:0005626~insoluble fraction 35 0.726895119418484 0.004087962926762653 RAP1GAP, SLC20A2, CNP, SLC26A2, CTNNB1, FDFT1, SLC16A1, PPP1R3C, ANK3, SLC2A1, PXMP4, LRRC59, CLEC2D, VKORC1, ATP8B1, SCARB2, SNAP23, SLC1A1, DNAJC1, SLC12A2, PSD3, NPR3, PPIF, LAMP2, UGT2B17, DGAT2, EPS8, NME1, VAMP8, SPCS3, JAK2, SYTL2, UGT2B15, GRB14, ABCC5 303 825 11759 1.6464246424642466 0.7454296501413407 0.17753883083411393 5.4115629369228095
31 GOTERM_BP_FAT GO:0007162~negative regulation of cell adhesion 6 0.12461059190031153 0.004242756827532716 ERBB3, PODXL, TGFBI, JAK2, CD164, THBS1 317 43 12596 5.544420805516837 0.9997972558500708 0.3765086066474883 7.049378775205994
32 SP_PIR_KEYWORDS ribosome biogenesis 6 0.12461059190031153 0.004671268564776842 DDX56, EMG1, WDR12, BOP1, ZNHIT6, IMP4 406 48 17699 5.449199507389163 0.8498763933108406 0.31563183683698737 6.333149002616533
33 GOTERM_BP_FAT GO:0043627~response to estrogen stimulus 9 0.1869158878504673 0.004872971615510889 GSTM3, SOCS2, GATA3, ARNT2, ESR1, AURKA, NPY1R, GAL, CTNNB1 317 105 12596 3.4058584948174855 0.9999428463045964 0.40202015958520865 8.055662147597797
34 KEGG_PATHWAY hsa04350:TGF-beta signaling pathway 8 0.16614745586708204 0.004943919454078046 ID2, RBL2, ID1, ID4, DCN, ID3, THBS1, MYC 120 84 4719 3.745238095238095 0.4878227089546199 0.4878227089546199 5.6448956906667735
35 GOTERM_BP_FAT GO:0000387~spliceosomal snRNP biogenesis 5 0.10384215991692627 0.0049458686096250214 PRMT5, SNRPD3, SNRPC, GEMIN6, GEMIN5 317 28 12596 7.09553853086976 0.9999506355383218 0.39092507518959596 8.171394677998478
36 GOTERM_BP_FAT GO:0022613~ribonucleoprotein complex biogenesis 12 0.24922118380062305 0.005067677584419404 DDX56, EMG1, PRMT5, SNRPD3, WDR12, NPM3, BOP1, SNRPC, ZNHIT6, GEMIN6, IMP4, GEMIN5 317 177 12596 2.6938993744319095 0.9999613561771807 0.38360237557193677 8.364474593794835
37 SP_PIR_KEYWORDS P-loop 9 0.1869158878504673 0.005207290761133379 RAB2A, DDX17, MYO6, SRPR, MYO1B, DTYMK, EIF4A1, CNP, ABCC5 406 116 17699 3.3822617632070666 0.8793018960951379 0.29700849888227343 7.035547807543252
38 INTERPRO IPR004910:Yippee-like protein 3 0.06230529595015576 0.0056149477486152986 YPEL5, YPEL2, YPEL3 376 5 15425 24.61436170212766 0.9867589310375501 0.9867589310375501 8.237724745647125
39 GOTERM_BP_FAT GO:0031145~anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 7 0.14537902388369678 0.005670480285710916 CCNB1, PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, BUB3 317 65 12596 4.279155544770687 0.999988500844857 0.4036725307633122 9.314364611781933
40 GOTERM_BP_FAT GO:0042981~regulation of apoptosis 33 0.6853582554517134 0.005678039704743254 ERBB3, GPR109B, CLU, ARNT2, STK17A, PAWR, ADORA1, GCLM, TCF7L2, GLO1, CAT, THBS1, NQO1, MYC, WWOX, DEPDC6, SOCS2, SGK3, PHB, ESR1, GAL, PPIF, DHRS2, BTG2, NME1, BTG1, TXNDC5, BIK, JAK2, FOXC1, ID3, IGFBP3, TP53INP1 317 797 12596 1.6452390470573799 0.9999886743682781 0.3905203123241906 9.326217570710138
41 GOTERM_BP_FAT GO:0010560~positive regulation of glycoprotein biosynthetic process 3 0.06230529595015576 0.00596724672472087 PAWR, TCF7L2, CTNNB1 317 5 12596 23.841009463722397 0.9999936702117522 0.3927168712846214 9.778591960675875
42 SP_PIR_KEYWORDS endoplasmic reticulum 28 0.5815160955347871 0.005972390323436884 HAX1, RTN2, CANT1, FDFT1, DNAJB11, SRPR, LRRC59, VKORC1, CREB3L4, ARL6IP5, DNAJC1, MEST, RAB2A, RHBDF1, ARMC10, TMPRSS3, ABCG1, TMEM106C, UGT2B17, DGAT2, LASS2, PTP4A1, TXNDC5, SPCS3, SUMF2, UGT2B15, AHSA1, SEL1L 406 701 17699 1.7412563333169364 0.9116165047938325 0.2928987645921084 8.029659059412598
43 UP_SEQ_FEATURE topological domain:Lumenal 20 0.4153686396677051 0.006228636877458284 TM9SF2, MBTPS2, FUT8, RHBDF1, CANT1, LAMP2, MANEAL, B3GNT5, LASS2, ST8SIA4, B3GALNT2, LRRC59, SPCS3, VKORC1, CREB3L4, CHSY1, SCARB2, GALNT12, DNAJC1, SEL1L 406 438 17662 1.9864138380907392 0.9992748049738001 0.973070554662231 9.56624243034777
44 GOTERM_BP_FAT GO:0043067~regulation of programmed cell death 33 0.6853582554517134 0.006473323707969136 ERBB3, GPR109B, CLU, ARNT2, STK17A, PAWR, ADORA1, GCLM, TCF7L2, GLO1, CAT, THBS1, NQO1, MYC, WWOX, DEPDC6, SOCS2, SGK3, PHB, ESR1, GAL, PPIF, DHRS2, BTG2, NME1, BTG1, TXNDC5, BIK, JAK2, FOXC1, ID3, IGFBP3, TP53INP1 317 805 12596 1.6288888453474932 0.9999977140595818 0.4052114544726556 10.565081837710045
45 PIR_SUPERFAMILY PIRSF028804:protein yippee-like 3 0.06230529595015576 0.006513187332397129 YPEL5, YPEL2, YPEL3 179 5 6776 22.712849162011175 0.7593758172361181 0.7593758172361181 7.970209151497976
46 GOTERM_BP_FAT GO:0010941~regulation of cell death 33 0.6853582554517134 0.006906618763678103 ERBB3, GPR109B, CLU, ARNT2, STK17A, PAWR, ADORA1, GCLM, TCF7L2, GLO1, CAT, THBS1, NQO1, MYC, WWOX, DEPDC6, SOCS2, SGK3, PHB, ESR1, GAL, PPIF, DHRS2, BTG2, NME1, BTG1, TXNDC5, BIK, JAK2, FOXC1, ID3, IGFBP3, TP53INP1 317 808 12596 1.622840990723678 0.9999990446228864 0.41322951169658295 11.233326337670057
47 GOTERM_BP_FAT GO:0051437~positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle 7 0.14537902388369678 0.0070603705871561655 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7 317 68 12596 4.090369270736686 0.999999299047625 0.40835317609392174 11.469315873147856
48 GOTERM_BP_FAT GO:0043066~negative regulation of apoptosis 18 0.3738317757009346 0.007304013071047973 SOCS2, SGK3, ERBB3, CLU, ARNT2, ESR1, ADORA1, TCF7L2, GCLM, DHRS2, BTG2, NME1, TXNDC5, FOXC1, GLO1, CAT, THBS1, MYC 317 350 12596 2.043515096890491 0.9999995709257916 0.4076335637683516 11.842066446689648
49 GOTERM_CC_FAT GO:0042470~melanosome 8 0.16614745586708204 0.007403633255909434 RAB2A, HSP90AA1, CCT4, SLC2A1, SLC3A2, CTSD, SYTL2, CNP 303 88 11759 3.5280528052805282 0.9164251668786925 0.26673755979816227 9.600133877807249
50 GOTERM_CC_FAT GO:0048770~pigment granule 8 0.16614745586708204 0.007403633255909434 RAB2A, HSP90AA1, CCT4, SLC2A1, SLC3A2, CTSD, SYTL2, CNP 303 88 11759 3.5280528052805282 0.9164251668786925 0.26673755979816227 9.600133877807249
51 SP_PIR_KEYWORDS Chaperone 10 0.20768431983385255 0.008038074117354787 HSP90AA1, CCT4, DNAJB11, HSPB8, NPM3, DNAJC2, AHSA1, NDUFAF2, DNAJC1, TIMM8A 406 151 17699 2.8869931164975697 0.9619393450236251 0.3354012314794689 10.66457162725647
52 GOTERM_BP_FAT GO:0051443~positive regulation of ubiquitin-protein ligase activity 7 0.14537902388369678 0.008114216936483308 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7 317 70 12596 3.9735015772870668 0.9999999161832304 0.4298660167129129 13.071001306805584
53 GOTERM_BP_FAT GO:0043069~negative regulation of programmed cell death 18 0.3738317757009346 0.008307297362829657 SOCS2, SGK3, ERBB3, CLU, ARNT2, ESR1, ADORA1, TCF7L2, GCLM, DHRS2, BTG2, NME1, TXNDC5, FOXC1, GLO1, CAT, THBS1, MYC 317 355 12596 2.014733194117386 0.9999999432148228 0.42657780409748025 13.361479702038782
54 GOTERM_BP_FAT GO:0060548~negative regulation of cell death 18 0.3738317757009346 0.008515239235949976 SOCS2, SGK3, ERBB3, CLU, ARNT2, ESR1, ADORA1, TCF7L2, GCLM, DHRS2, BTG2, NME1, TXNDC5, FOXC1, GLO1, CAT, THBS1, MYC 317 356 12596 2.009073831212562 0.9999999626675173 0.4240432146144707 13.673293715777557
55 SMART SM00353:HLH 8 0.16614745586708204 0.008935402761169612 ASCL1, ID2, ID1, ARNT2, ID4, ID3, MYC, MXD4 197 103 8614 3.396185500961017 0.7806025002740999 0.7806025002740999 10.362040176356402
56 SP_PIR_KEYWORDS mitosis 11 0.2284527518172378 0.009621683092711145 CCNB1, CDCA8, PLK1, SPAG5, RUVBL1, CEP55, ANAPC7, ZWILCH, CDCA5, CCNG2, BUB3 406 183 17699 2.620380090984953 0.9800724000624614 0.3527820476798511 12.636916356504646
57 UP_SEQ_FEATURE domain:EGF-like 2; calcium-binding 6 0.12461059190031153 0.009750995975383004 HMCN1, NPNT, EFEMP1, LRP8, CELSR2, THBS1 406 57 17662 4.579206637282862 0.9999880796965516 0.9771565109766879 14.58901232651172
58 UP_SEQ_FEATURE domain:Helix-loop-helix motif 8 0.16614745586708204 0.010031282192178338 ASCL1, ID2, ID1, ARNT2, ID4, ID3, MYC, MXD4 406 104 17662 3.3463433118605534 0.9999914090243385 0.9458609510710853 14.977241102503669
59 GOTERM_BP_FAT GO:0034660~ncRNA metabolic process 13 0.2699896157840083 0.01137895385550558 EMG1, MKI67IP, BOP1, DARS2, IARS, DDX56, METTL1, FARSB, WDR4, WDR12, NPM3, IMP4, RPP40 317 225 12596 2.295800911321416 0.999999999885263 0.5109359632906534 17.86141744374319
60 BBID 71.Id_proteins_G0-to-S_cell_cycle 3 0.06230529595015576 0.011720115295995537 ID2, ID1, ID3 14 5 354 15.17142857142857 0.2006827934251889 0.2006827934251889 8.456362108493476
61 GOTERM_BP_FAT GO:0031396~regulation of protein ubiquitination 8 0.16614745586708204 0.012194270828671475 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7, BUB3 317 99 12596 3.210910365484498 0.9999999999779666 0.524595736219902 19.018337334668757
62 INTERPRO IPR001092:Basic helix-loop-helix dimerisation region bHLH 8 0.16614745586708204 0.012811306300896504 ASCL1, ID2, ID1, ARNT2, ID4, ID3, MYC, MXD4 376 103 15425 3.1863251394340013 0.9999499582306484 0.9929259792655345 17.869679203774613
63 GOTERM_CC_FAT GO:0005759~mitochondrial matrix 13 0.2699896157840083 0.013481850366651336 MRPS17, MRPL3, MRPS12, MRPS25, DARS2, PPIF, COQ3, C1QBP, PPM1K, ALDH1B1, LRRC59, MRPL16, ETFA 303 225 11759 2.242273560689402 0.9892577165189637 0.39572732430723434 16.83560333032357
64 GOTERM_CC_FAT GO:0031980~mitochondrial lumen 13 0.2699896157840083 0.013481850366651336 MRPS17, MRPL3, MRPS12, MRPS25, DARS2, PPIF, COQ3, C1QBP, PPM1K, ALDH1B1, LRRC59, MRPL16, ETFA 303 225 11759 2.242273560689402 0.9892577165189637 0.39572732430723434 16.83560333032357
65 GOTERM_BP_FAT GO:0032269~negative regulation of cellular protein metabolic process 11 0.2284527518172378 0.014368196132849946 PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, THBS1, EIF2B3, IGFBP3, BUB3, DNAJC1, IGFBP5 317 178 12596 2.455534682593131 0.9999999999997312 0.5731483359225439 22.028538211405824
66 INTERPRO IPR014729:Rossmann-like alpha/beta/alpha sandwich fold 5 0.10384215991692627 0.014462380264418085 IARS, ASS1, ASNSD1, FLAD1, ETFA 376 39 15425 5.259478996181124 0.9999861636108359 0.9759928324856477 19.942058214380122
67 INTERPRO IPR011510:Sterile alpha motif homology 2 5 0.10384215991692627 0.0171474800452878 EPHA4, SASH1, SAMD12, PPFIBP2, DGKH 376 41 15425 5.002919045147899 0.9999982976179869 0.9638786265266556 23.208267139860617
68 GOTERM_BP_FAT GO:0031398~positive regulation of protein ubiquitination 7 0.14537902388369678 0.01785993132285533 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, ANAPC7 317 83 12596 3.351145908555357 0.9999999999999998 0.6429184614931377 26.643915486783342
69 GOTERM_BP_FAT GO:0051248~negative regulation of protein metabolic process 11 0.2284527518172378 0.018331493899884484 PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, THBS1, EIF2B3, IGFBP3, BUB3, DNAJC1, IGFBP5 317 185 12596 2.3626225594679853 0.9999999999999999 0.6422305674919395 27.24712958165454
70 GOTERM_BP_FAT GO:0007507~heart development 12 0.24922118380062305 0.018675145355360467 PTPRJ, ID2, ERBB4, ADM, ID1, ERBB3, PDLIM3, ADIPOR2, FOXC1, ID3, MB, CTNNB1 317 213 12596 2.2385924379082063 1.0 0.6390487292695612 27.683775972788293
71 GOTERM_CC_FAT GO:0000323~lytic vacuole 12 0.24922118380062305 0.019207734586999425 LAMP2, TSPAN1, GOT1, LITAF, GLA, CTSD, CTSA, CAT, SCARB2, SNAP23, CD164, ACPP 303 209 11759 2.228243877019281 0.9984628056011813 0.47679380290229734 23.157326454328665
72 GOTERM_CC_FAT GO:0005764~lysosome 12 0.24922118380062305 0.019207734586999425 LAMP2, TSPAN1, GOT1, LITAF, GLA, CTSD, CTSA, CAT, SCARB2, SNAP23, CD164, ACPP 303 209 11759 2.228243877019281 0.9984628056011813 0.47679380290229734 23.157326454328665
73 SP_PIR_KEYWORDS lysosome 9 0.1869158878504673 0.019962908415590123 LAMP2, TSPAN1, LITAF, GLA, CTSD, CTSA, SCARB2, CD164, ACPP 406 147 17699 2.6689956770885694 0.9997160658147356 0.5581022722542024 24.555211162397338
74 GOTERM_BP_FAT GO:0043086~negative regulation of catalytic activity 14 0.29075804776739356 0.02100283338634322 DEPDC6, NPR3, NPY1R, ADORA1, PKIA, PSMB5, PSMF1, PSMD12, GLA, PSMD3, ANAPC7, NQO1, GADD45B, BUB3 317 274 12596 2.0302562803656543 1.0 0.672800702769395 30.577013986613053
75 GOTERM_CC_FAT GO:0016023~cytoplasmic membrane-bounded vesicle 23 0.47767393561786087 0.021976544915650847 RAB2A, HSP90AA1, MYO6, SGK3, CLU, SLC3A2, DENND1A, CNP, NPY1R, GAL, SYNGR3, LAMP2, DAB2, PLEKHF2, CCT4, STX12, CRISPLD2, SLC2A1, CTSD, SYTL2, SNAP23, THBS1, RAB27B 303 541 11759 1.649902698218066 0.9994020618643026 0.49070577660382 26.051823305121967
76 GOTERM_BP_FAT GO:0000280~nuclear division 12 0.24922118380062305 0.022412689264801413 CCNB1, CDCA8, PLK1, SPAG5, AURKA, RUVBL1, CEP55, ANAPC7, ZWILCH, CDCA5, CCNG2, BUB3 317 219 12596 2.1772611382394884 1.0 0.687279246985911 32.27602844790749
77 GOTERM_BP_FAT GO:0007067~mitosis 12 0.24922118380062305 0.022412689264801413 CCNB1, CDCA8, PLK1, SPAG5, AURKA, RUVBL1, CEP55, ANAPC7, ZWILCH, CDCA5, CCNG2, BUB3 317 219 12596 2.1772611382394884 1.0 0.687279246985911 32.27602844790749
78 GOTERM_BP_FAT GO:0030182~neuron differentiation 19 0.3946002076843198 0.023194234091410904 RET, MYO6, PLA2G10, ERBB3, EFNA1, CLU, NTN4, CELSR2, CNP, CXCL12, ASCL1, EPHA4, ADM, BTG2, ANK3, JAK2, ID4, ID3, TOP2B 317 429 12596 1.7598258733905423 1.0 0.6906780599917217 33.20091572764709
79 GOTERM_BP_FAT GO:0051436~negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle 6 0.12461059190031153 0.02335199178290231 PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, BUB3 317 65 12596 3.6678476098034456 1.0 0.684195739049846 33.38615879272467
80 GOTERM_BP_FAT GO:0030335~positive regulation of cell migration 7 0.14537902388369678 0.024309173943788225 PRR5, ARHGAP5, ERBB4, PTP4A1, JAK2, ARHGAP8, THBS1, CXCL12 317 89 12596 3.125225959663985 1.0 0.690216580702974 34.49977396642056
81 GOTERM_BP_FAT GO:0001503~ossification 8 0.16614745586708204 0.024621941275407067 TWSG1, TUFT1, FHL2, FOXC1, IGFBP3, SLC26A2, WWOX, IGFBP5 317 114 12596 2.788422159499696 1.0 0.6863698828451602 34.8598399269069
82 GOTERM_CC_FAT GO:0044429~mitochondrial part 24 0.4984423676012461 0.024666070978496997 MRPS17, MRPL3, TIMM17A, PHB, MRPS25, MRPS12, PNPT1, C20ORF7, DARS2, CHCHD4, ATP5G1, TIMM8A, PPIF, COQ3, NNT, C1QBP, ALDH1B1, PPM1K, C3ORF31, LRRC59, MRPL16, BIK, CAT, ETFA 303 578 11759 1.6114289629655008 0.9997616511868718 0.5009993827820078 28.766432027947687
83 GOTERM_BP_FAT GO:0007167~enzyme linked receptor protein signaling pathway 16 0.3322949117341641 0.025019175380326455 PTPRJ, TWSG1, RET, ERBB4, FUT8, SOCS2, ERBB3, EFNA1, TIPARP, EPHA4, EPS8, ID1, FOXC1, JAK2, AREG, BAMBI 317 340 12596 1.8698830951939136 1.0 0.6839021368244911 35.31445918338198
84 GOTERM_BP_FAT GO:0000087~M phase of mitotic cell cycle 12 0.24922118380062305 0.02508322065456582 CCNB1, CDCA8, PLK1, SPAG5, AURKA, RUVBL1, CEP55, ANAPC7, ZWILCH, CDCA5, CCNG2, BUB3 317 223 12596 2.1382071267912464 1.0 0.6766531220395888 35.38747621733243
85 GOTERM_BP_FAT GO:0007169~transmembrane receptor protein tyrosine kinase signaling pathway 12 0.24922118380062305 0.025938360884523403 PTPRJ, EPHA4, RET, SOCS2, ERBB4, EPS8, ERBB3, EFNA1, TIPARP, JAK2, FOXC1, AREG 317 224 12596 2.1286615592609284 1.0 0.6810238100568693 36.35500049686833
86 GOTERM_BP_FAT GO:0051444~negative regulation of ubiquitin-protein ligase activity 6 0.12461059190031153 0.02623250136631179 PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, BUB3 317 67 12596 3.558359621451104 1.0 0.6773474454259021 36.6846315108575
87 GOTERM_BP_FAT GO:0051352~negative regulation of ligase activity 6 0.12461059190031153 0.02623250136631179 PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, BUB3 317 67 12596 3.558359621451104 1.0 0.6773474454259021 36.6846315108575
88 GOTERM_BP_FAT GO:0030334~regulation of cell migration 10 0.20768431983385255 0.026718016071559735 PRR5, ARHGAP5, ERBB4, PTP4A1, JAK2, ARHGAP8, THBS1, ADORA1, IGFBP3, CXCL12, IGFBP5 317 169 12596 2.351184365258619 1.0 0.6764471850756544 37.22521260677847
89 GOTERM_MF_FAT GO:0005070~SH3/SH2 adaptor activity 5 0.10384215991692627 0.027662329616240256 SH3BGRL, SOCS2, EPS8, GRB14, BLNK 284 49 12042 4.326674331704513 0.9999999619266638 0.9999999619266638 33.97607381508314
90 GOTERM_BP_FAT GO:0022618~ribonucleoprotein complex assembly 6 0.12461059190031153 0.027754099046780764 PRMT5, SNRPD3, SNRPC, ZNHIT6, GEMIN6, GEMIN5 317 68 12596 3.506030803488588 1.0 0.682994968355489 38.36430481814516
91 GOTERM_CC_FAT GO:0005773~vacuole 13 0.2699896157840083 0.028190137555950984 TSPAN1, LITAF, CTSA, CD164, ACPP, LAMP2, GOT1, GLA, MAP1LC3B, CTSD, SNAP23, SCARB2, CAT 303 250 11759 2.018046204620462 0.9999288532714689 0.5203383522606182 32.18371664505166
92 GOTERM_BP_FAT GO:0048285~organelle fission 12 0.24922118380062305 0.029010507744203957 CCNB1, CDCA8, PLK1, SPAG5, AURKA, RUVBL1, CEP55, ANAPC7, ZWILCH, CDCA5, CCNG2, BUB3 317 228 12596 2.091316619624772 1.0 0.6919783766415676 39.719512872168806
93 GOTERM_BP_FAT GO:0051046~regulation of secretion 11 0.2284527518172378 0.029495769359686983 MYO6, PLA2G10, ERBB3, GPR109B, JAK2, RAB26, NPY1R, RAB27B, ADORA1, TCF7L2, DNAJC1 317 200 12596 2.1854258675078864 1.0 0.690902559867366 40.23538096837371
94 GOTERM_BP_FAT GO:0010559~regulation of glycoprotein biosynthetic process 3 0.06230529595015576 0.029714096251763272 PAWR, TCF7L2, CTNNB1 317 11 12596 10.836822483510181 1.0 0.6865681292886424 40.46611944643706
95 GOTERM_BP_FAT GO:0032270~positive regulation of cellular protein metabolic process 12 0.24922118380062305 0.029759011135422057 CCNB1, PSMB5, PSMF1, PSMD12, PLA2G10, PLK1, PSMD3, JAK2, ANAPC7, THBS1, ADORA1, IL20 317 229 12596 2.0821842326395106 1.0 0.6801905872482024 40.513483505104716
96 GOTERM_MF_FAT GO:0005548~phospholipid transporter activity 4 0.08307372793354102 0.029903433422523877 PITPNA, PLSCR3, ATP8B1, ABCG1 284 29 12042 5.848470131131617 0.9999999906606809 0.999903359847605 36.19271281216274
97 GOTERM_MF_FAT GO:0003735~structural constituent of ribosome 9 0.1869158878504673 0.02996045153748161 RPS26, MRPS17, MRPL3, MRPL15, MRPL14, MRPS25, MRPS12, MRPL16, MRPS6 284 155 12042 2.4620172648796004 0.9999999909890737 0.9979190747472312 36.248192533581246
98 GOTERM_BP_FAT GO:0016072~rRNA metabolic process 7 0.14537902388369678 0.030747401743986637 DDX56, EMG1, WDR12, NPM3, MKI67IP, BOP1, IMP4 317 94 12596 2.958990536277603 1.0 0.6854673749995595 41.54683025912372
99 GOTERM_CC_FAT GO:0031988~membrane-bounded vesicle 23 0.47767393561786087 0.030902151910764467 RAB2A, HSP90AA1, MYO6, SGK3, CLU, SLC3A2, DENND1A, CNP, NPY1R, GAL, SYNGR3, LAMP2, DAB2, PLEKHF2, CCT4, STX12, CRISPLD2, SLC2A1, CTSD, SYTL2, SNAP23, THBS1, RAB27B 303 559 11759 1.5967752410303644 0.9999720238366384 0.5270986187321379 34.7094478717507
100 UP_SEQ_FEATURE mutagenesis site 60 1.2461059190031152 0.03102622846719213 SAT1, TSPAN1, SLC20A2, GPR109B, MKI67IP, C14ORF4, CTNNB1, CANT1, AUH, MTHFD1, PGR, AKR1C3, CDCA8, DAB2, PBXIP1, DNAJB11, MAP1LC3B, KCNK6, PRMT5, CREB3L4, WWOX, SGK3, ESR1, SLC3A2, TLE1, RFTN1, PPM1K, NME1, TFPI, FOXC1, RUVBL1, UBE2S, LITAF, ERBB4, FUT8, CTSA, CHCHD4, STK17A, CEP55, TCF7L2, PSMB5, PPP1R3C, PEG10, CENPA, METTL1, SCARB2, PTS, THBS1, BLNK, MBTPS2, RHBDF1, DGKH, NXF1, CORO1B, PLK1, PTP4A1, PLSCR3, SUMF2, SYTL2, HIST1H3H 406 2023 17662 1.2902361756061451 0.9999999999999999 0.999319854548544 39.78346277591982
101 GOTERM_CC_FAT GO:0030529~ribonucleoprotein complex 21 0.43613707165109034 0.032100264253347596 MRPS17, MRPL3, EMG1, MRPS25, SNRPD3, MRPS12, MRPS6, BOP1, PRPF4, RPS26, MRPL15, MRPL14, MRPL16, WDR12, SNRPC, GEMIN6, ZNHIT6, RBM28, IMP4, RPP40, GEMIN5 303 498 11759 1.6365064217265102 0.9999814926597075 0.51639631586907 35.797267957632386
102 GOTERM_BP_FAT GO:0060348~bone development 8 0.16614745586708204 0.033933758657429015 TWSG1, TUFT1, FHL2, FOXC1, IGFBP3, SLC26A2, WWOX, IGFBP5 317 122 12596 2.605574804778404 1.0 0.7150316756021201 44.76420427026545
103 GOTERM_BP_FAT GO:0030900~forebrain development 9 0.1869158878504673 0.034155416791400786 ASCL1, TWSG1, DKK1, ERBB4, SOX3, LRP8, ID4, TOP2B, CTNNB1 317 149 12596 2.4001016238646713 1.0 0.7109498759998971 44.98169847947029
104 GOTERM_CC_FAT GO:0000313~organellar ribosome 5 0.10384215991692627 0.03426991308569578 MRPS17, MRPL3, MRPS25, MRPS12, MRPL16 303 48 11759 4.042560506050605 0.999991253698036 0.5170924124334431 37.724569849009804
105 GOTERM_CC_FAT GO:0005761~mitochondrial ribosome 5 0.10384215991692627 0.03426991308569578 MRPS17, MRPL3, MRPS25, MRPS12, MRPL16 303 48 11759 4.042560506050605 0.999991253698036 0.5170924124334431 37.724569849009804
106 UP_SEQ_FEATURE domain:Thyroglobulin type-1 3 0.06230529595015576 0.03462131525423547 TACSTD2, IGFBP3, IGFBP5 406 13 17662 10.03902993558166 1.0 0.9988800270210252 43.2800073639079
107 SP_PIR_KEYWORDS cell cycle 18 0.3738317757009346 0.03493954832462988 RBL2, AURKA, CEP55, APPL2, CCNG2, CCNB1, CDCA8, PRR5, PLK1, SPAG5, PTP4A1, SIAH2, ANAPC7, RUVBL1, ZWILCH, ARHGAP8, CDCA5, UBE2S, BUB3 406 458 17699 1.7132854346376407 0.9999994446330829 0.7300238156472298 39.161838310016186
108 GOTERM_BP_FAT GO:0014068~positive regulation of phosphoinositide 3-kinase cascade 3 0.06230529595015576 0.03507535263791957 ERBB3, JAK2, CAT 317 12 12596 9.933753943217665 1.0 0.7143009692671705 45.8757621957146
109 GOTERM_BP_FAT GO:0030856~regulation of epithelial cell differentiation 4 0.08307372793354102 0.035315954281395494 BTG1, NME1, CTNNB1, IL20 317 29 12596 5.480691830740781 1.0 0.7105623410124362 46.10732955706751
110 KEGG_PATHWAY hsa05216:Thyroid cancer 4 0.08307372793354102 0.035470378862347454 RET, MYC, TCF7L2, CTNNB1 120 29 4719 5.424137931034482 0.992368640884073 0.9126423494138775 34.51824226850436
111 GOTERM_BP_FAT GO:0042127~regulation of cell proliferation 29 0.6022845275181723 0.03574167111734511 ERBB4, ERBB3, CLU, ARNT2, PAWR, ADORA1, CTNNB1, PGR, CDCA7, ARHGAP5, THBS1, MYC, PHB, GAL, CD164, MXD4, DHRS2, C19ORF10, ID2, ADM, BTG2, BTG1, NME1, GRN, ID4, JAK2, PMP22, IGFBP3, IGFBP5 317 781 12596 1.475435924984954 1.0 0.7088056053283087 46.514776722315965
112 GOTERM_BP_FAT GO:0051272~positive regulation of cell motion 7 0.14537902388369678 0.03663365305290105 PRR5, ARHGAP5, ERBB4, PTP4A1, JAK2, ARHGAP8, THBS1, CXCL12 317 98 12596 2.8382154123479046 1.0 0.7117855808124752 47.35909018715523
113 GOTERM_BP_FAT GO:0040017~positive regulation of locomotion 7 0.14537902388369678 0.03663365305290105 PRR5, ARHGAP5, ERBB4, PTP4A1, JAK2, ARHGAP8, THBS1, CXCL12 317 98 12596 2.8382154123479046 1.0 0.7117855808124752 47.35909018715523
114 SMART SM00320:WD40 12 0.24922118380062305 0.03668040913537969 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, BCAS3, PRPF4, BUB3, GEMIN5 197 262 8614 2.0027124423606 0.9981920086821404 0.9574795188425669 36.58401798229558
115 GOTERM_CC_FAT GO:0016323~basolateral plasma membrane 11 0.2284527518172378 0.037060378686791906 LIMA1, PGM5, ERBB4, SLC12A2, S100A7, ERBB3, ANK3, SLC2A1, FHL2, ADORA1, CTNNB1 303 203 11759 2.1029280267928274 0.9999966727539423 0.5238215893551419 40.12457004922019
116 GOTERM_BP_FAT GO:0008285~negative regulation of cell proliferation 16 0.3322949117341641 0.03707414211838215 PHB, PAWR, GAL, CD164, ADORA1, MXD4, DHRS2, ADM, BTG2, BTG1, NME1, JAK2, THBS1, PMP22, IGFBP3, IGFBP5 317 358 12596 1.7758666267204766 1.0 0.7102251908644321 47.77139359510735
117 GOTERM_MF_FAT GO:0019838~growth factor binding 7 0.14537902388369678 0.0372554502897087 IL1R1, HAX1, ERBB3, THBS1, IGFBP3, CRIM1, IGFBP5 284 105 12042 2.8267605633802813 0.9999999999091675 0.996912832414735 42.98688455451632
118 GOTERM_CC_FAT GO:0005792~microsome 12 0.24922118380062305 0.037394185932915366 PPP1R3C, UGT2B17, DGAT2, NME1, LRRC59, VKORC1, SPCS3, SNAP23, UGT2B15, GRB14, DNAJC1, FDFT1 303 232 11759 2.007340389211335 0.9999970365850185 0.5069654437554939 40.405857286206945
119 GOTERM_BP_FAT GO:0031397~negative regulation of protein ubiquitination 6 0.12461059190031153 0.038054226996041274 PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, BUB3 317 74 12596 3.2217580356381617 1.0 0.7139310879420364 48.677879254430614
120 GOTERM_BP_FAT GO:0048812~neuron projection morphogenesis 11 0.2284527518172378 0.03809863762008108 EPHA4, PLA2G10, ADM, ERBB3, ANK3, CLU, JAK2, CNP, CELSR2, TOP2B, CXCL12 317 209 12596 2.0913166196247714 1.0 0.7086187632204074 48.71860185202578
121 GOTERM_BP_FAT GO:0043392~negative regulation of DNA binding 5 0.10384215991692627 0.0386179945366188 ID2, ID1, JAK2, ID3, CAT 317 51 12596 3.895589781653986 1.0 0.7079214547233035 49.19257599745443
122 GOTERM_BP_FAT GO:0051247~positive regulation of protein metabolic process 12 0.24922118380062305 0.03866636593120793 CCNB1, PSMB5, PSMF1, PSMD12, PLA2G10, PLK1, PSMD3, JAK2, ANAPC7, THBS1, ADORA1, IL20 317 239 12596 1.995063553449573 1.0 0.702798925636877 49.236509902685185
123 UP_SEQ_FEATURE repeat:WD 3 12 0.24922118380062305 0.03891193717053003 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, BCAS3, PRPF4, BUB3, GEMIN5 406 261 17662 2.0001132438706755 1.0 0.9985842048724054 47.20371183707213
124 GOTERM_CC_FAT GO:0033279~ribosomal subunit 8 0.16614745586708204 0.03916081699910838 RPS26, MRPS17, MRPL3, MRPL15, MRPS25, MRPS12, MRPL16, MRPS6 303 123 11759 2.524135340363305 0.999998395515367 0.5045296606498375 41.87425951858451
125 UP_SEQ_FEATURE domain:EGF-like 4; calcium-binding 4 0.08307372793354102 0.03930041490491055 HMCN1, NPNT, EFEMP1, CELSR2 406 33 17662 5.273025824749963 1.0 0.9969679797042439 47.54610583769764
126 UP_SEQ_FEATURE short sequence motif:DEAD box 4 0.08307372793354102 0.03930041490491055 DDX17, DDX56, EIF4A1, DDX10 406 33 17662 5.273025824749963 1.0 0.9969679797042439 47.54610583769764
127 SP_PIR_KEYWORDS cell division 12 0.24922118380062305 0.03961030413950267 CCNB1, CDCA8, PLK1, SPAG5, RUVBL1, CEP55, ANAPC7, ZWILCH, CDCA5, CCNG2, UBE2S, BUB3 406 263 17699 1.989061417145854 0.9999999221543797 0.7443752806039394 43.1495345401382
128 GOTERM_BP_FAT GO:0043434~response to peptide hormone stimulus 9 0.1869158878504673 0.040290163965768525 GOT1, SOCS2, BTG2, ADM, ERBB3, JAK2, GAL, EIF2B3, ABCC5 317 154 12596 2.3221762464664675 1.0 0.7124017498732349 50.69075313679758
129 GOTERM_BP_FAT GO:0014066~regulation of phosphoinositide 3-kinase cascade 3 0.06230529595015576 0.0407780587468878 ERBB3, JAK2, CAT 317 13 12596 9.169619024508615 1.0 0.7114163188161065 51.11997796192558
130 GOTERM_BP_FAT GO:0007219~Notch signaling pathway 5 0.10384215991692627 0.041040792651066894 ASCL1, NLE1, WDR12, FOXC1, SEL1L 317 52 12596 3.820674593545256 1.0 0.7084521760919982 51.34965758829342
131 OMIM_DISEASE Myocardial infarction, susceptibility to 3 0.06230529595015576 0.04183368103061792 ESR1, LRP8, GCLM 78 13 3016 8.923076923076923 0.9993575565366913 0.9993575565366913 40.68902533502485
132 GOTERM_CC_FAT GO:0005783~endoplasmic reticulum 34 0.7061266874350987 0.04226426516689148 HAX1, S100A7, CTSA, ADORA1, RTN2, CANT1, FDFT1, DNAJB11, SRPR, ANK3, LRRC59, VKORC1, CREB3L4, CAT, ARL6IP5, DNAJC1, RAB2A, RHBDF1, ARMC10, TPBG, TMPRSS3, ABCG1, TMEM49, TMEM106C, UGT2B17, DGAT2, LASS2, PTP4A1, TXNDC5, SPCS3, SUMF2, UGT2B15, AHSA1, SEL1L 303 943 11759 1.3992489386796578 0.9999994554206908 0.5138133194607584 44.37293520499102
133 GOTERM_BP_FAT GO:0048666~neuron development 15 0.3115264797507788 0.04238598049317027 RET, MYO6, PLA2G10, ERBB3, CLU, NTN4, CELSR2, CNP, CXCL12, ASCL1, EPHA4, ADM, ANK3, JAK2, TOP2B 317 334 12596 1.784506696386407 1.0 0.7150314241546482 52.50977016602889
134 GOTERM_BP_FAT GO:0031401~positive regulation of protein modification process 10 0.20768431983385255 0.042486598187355645 CCNB1, PSMB5, PSMF1, PSMD12, PLK1, PSMD3, JAK2, ANAPC7, ADORA1, IL20 317 184 12596 2.159511726786449 1.0 0.7107444166139167 52.595488878260824
135 GOTERM_BP_FAT GO:0043161~proteasomal ubiquitin-dependent protein catabolic process 7 0.14537902388369678 0.04319769531396844 CCNB1, PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, BUB3 317 102 12596 2.7269128471577906 1.0 0.7117424834043682 53.19714902427013
136 GOTERM_BP_FAT GO:0010498~proteasomal protein catabolic process 7 0.14537902388369678 0.04319769531396844 CCNB1, PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, BUB3 317 102 12596 2.7269128471577906 1.0 0.7117424834043682 53.19714902427013
137 GOTERM_BP_FAT GO:0042476~odontogenesis 5 0.10384215991692627 0.04354797497553736 ERBB4, TUFT1, ERBB3, FOXC1, CTNNB1 317 53 12596 3.748586393667044 1.0 0.7096870448286035 53.49087010750002
138 GOTERM_CC_FAT GO:0031981~nuclear lumen 48 0.9968847352024922 0.04361842117971825 POLR2F, FKBP4, LYAR, SNRPD3, YPEL2, ARNT2, YPEL3, NOC3L, PDLIM3, MKI67IP, MYBL1, BOP1, TCF7L2, CTNNB1, CORO2A, WDR75, CDCA8, NPM3, WDR12, NAT10, GEMIN6, TOP2B, IMP4, MYC, RBM28, BUB3, GEMIN5, MYO6, POLR3H, RBL2, EMG1, PHB, PNO1, TLE1, NXF1, PRPF4, APPL2, CCNB1, DDX56, NAV2, PLK1, NLE1, WDR4, JAK2, SNRPC, RUVBL1, ANAPC7, RPP40 303 1429 11759 1.3035772436585855 0.9999996605141999 0.5080240348870226 45.43170535910763
139 KEGG_PATHWAY hsa00330:Arginine and proline metabolism 5 0.10384215991692627 0.04363497934777164 SAT1, GOT1, SRM, ASS1, ALDH1B1 120 53 4719 3.709905660377358 0.9975778711498603 0.8657031743227197 40.72961686911849
140 GOTERM_CC_FAT GO:0042598~vesicular fraction 12 0.24922118380062305 0.04363961435972748 PPP1R3C, UGT2B17, DGAT2, NME1, LRRC59, VKORC1, SPCS3, SNAP23, UGT2B15, GRB14, DNAJC1, FDFT1 303 238 11759 1.956735169315251 0.9999996630176077 0.4920741363921447 45.44812623394905
141 UP_SEQ_FEATURE short sequence motif:KKRRAP 2 2 0.04153686396677051 0.04533662772882098 COBLL1, COBL 406 2 17662 43.502463054187196 1.0 0.9974317398668975 52.605825946215504
142 UP_SEQ_FEATURE short sequence motif:KKRRAP 1 2 0.04153686396677051 0.04533662772882098 COBLL1, COBL 406 2 17662 43.502463054187196 1.0 0.9974317398668975 52.605825946215504
143 UP_SEQ_FEATURE region of interest:Interaction with AKAP13 2 0.04153686396677051 0.04533662772882098 NME1, ESR1 406 2 17662 43.502463054187196 1.0 0.9974317398668975 52.605825946215504
144 GOTERM_CC_FAT GO:0019898~extrinsic to membrane 20 0.4153686396677051 0.04537472504846336 MYO6, RAP1GAP, EPB41L4A, DENND1A, VPS37C, C20ORF7, APPL2, CTNNB1, CRBN, ARHGAP5, SRPR, DOK7, C3ORF31, SYTL5, JAK2, SYTL2, SNAP23, APPBP2, PDZK1, GRB14 303 486 11759 1.5970609406619671 0.9999998162623386 0.4905060263350549 46.777100303390974
145 INTERPRO IPR019782:WD40 repeat 2 11 0.2284527518172378 0.045743066621956874 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, PRPF4, BUB3, GEMIN5 376 222 15425 2.0327175579835157 0.9999999999999998 0.999247348759172 51.074386979750706
146 GOTERM_MF_FAT GO:0008176~tRNA (guanine-N7-)-methyltransferase activity 2 0.04153686396677051 0.04645176425673228 METTL1, WDR4 284 2 12042 42.401408450704224 0.9999999999997372 0.9969525482721424 50.53645963288491
147 GOTERM_CC_FAT GO:0005730~nucleolus 26 0.5399792315680166 0.04659967777882893 POLR2F, YPEL2, SNRPD3, LYAR, FKBP4, NOC3L, YPEL3, PDLIM3, MKI67IP, BOP1, MYBL1, WDR75, CDCA8, NPM3, WDR12, NAT10, TOP2B, RBM28, IMP4, BUB3, EMG1, PNO1, DDX56, NAV2, NLE1, RPP40 303 683 11759 1.4773398276870144 0.999999880340187 0.4852679863090641 47.697198038047404
148 SP_PIR_KEYWORDS transmembrane protein 22 0.4569055036344756 0.04695536208401456 PTPRJ, RET, IL1R1, SLC3A2, TRGC2, ITGB5, COLEC12, NPR3, ATP5G1, ADORA1, TPBG, SLC7A5, FDFT1, LAMP2, SRPR, TACSTD2, CXCR7, SCARB2, AREG, UGT2B15, PMP22, SLC1A1 406 619 17699 1.5493685190638007 0.9999999965257337 0.7764898952452817 48.932611672146486
149 SP_PIR_KEYWORDS ribonucleoprotein 12 0.24922118380062305 0.046992460071287684 RPS26, MRPS17, MRPL3, MRPL15, MRPL14, MRPS25, MRPS12, SNRPD3, MRPL16, MRPS6, SNRPC, IMP4 406 270 17699 1.9374931581828132 0.9999999965800768 0.7515226067977534 48.96038124621891
150 KEGG_PATHWAY hsa00053:Ascorbate and aldarate metabolism 3 0.06230529595015576 0.04708848113699719 UGT2B17, ALDH1B1, UGT2B15 120 14 4719 8.426785714285714 0.9985137294825388 0.8036529115234698 43.19081724146932
151 BIOCARTA h_p53hypoxiaPathway:Hypoxia and p53 in the Cardiovascular system 4 0.08307372793354102 0.047122471602742036 HSP90AA1, FHL2, NQO1, IGFBP3 50 24 1418 4.726666666666667 0.9817997200770427 0.9817997200770427 40.363074335881066
152 UP_SEQ_FEATURE repeat:WD 1 12 0.24922118380062305 0.04763116153667807 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, BCAS3, PRPF4, BUB3, GEMIN5 406 270 17662 1.9334428024083197 1.0 0.9964701279778626 54.406161326017475
153 UP_SEQ_FEATURE repeat:WD 2 12 0.24922118380062305 0.04763116153667807 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, BCAS3, PRPF4, BUB3, GEMIN5 406 270 17662 1.9334428024083197 1.0 0.9964701279778626 54.406161326017475
154 INTERPRO IPR019025:Cordon-bleu domain 2 0.04153686396677051 0.048032870535733865 COBLL1, COBL 376 2 15425 41.023936170212764 1.0 0.9981651102858262 52.83645975242981
155 INTERPRO IPR012972:NLE 2 0.04153686396677051 0.048032870535733865 NLE1, WDR12 376 2 15425 41.023936170212764 1.0 0.9981651102858262 52.83645975242981
156 INTERPRO IPR012918:RTP801, C-terminal 2 0.04153686396677051 0.048032870535733865 DDIT4L, DDIT4 376 2 15425 41.023936170212764 1.0 0.9981651102858262 52.83645975242981
157 SP_PIR_KEYWORDS rrna processing 5 0.10384215991692627 0.048362277172289886 DDX56, EMG1, WDR12, BOP1, IMP4 406 60 17699 3.632799671592775 0.9999999980900681 0.7377385091649713 49.97599118105892
158 SP_PIR_KEYWORDS Apoptosis 15 0.3115264797507788 0.048889438660058404 RNF144B, LITAF, GPR109B, CLU, PAWR, STK17A, DDIT4, CTNNB1, PEG10, TSC22D3, BIK, SIAH2, GADD45B, WWOX, TP53INP1 406 373 17699 1.7530936752994626 0.9999999984739923 0.7188278551113422 50.361814738950564
159 SP_PIR_KEYWORDS wd repeat 12 0.24922118380062305 0.04901634711984486 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, BCAS3, PRPF4, BUB3, GEMIN5 406 272 17699 1.9232468849608808 0.9999999985542743 0.6980013141693762 50.45428407302928
160 GOTERM_BP_FAT GO:0015914~phospholipid transport 4 0.08307372793354102 0.049039720288727336 PLA2G10, PITPNA, ATP8B1, ABCG1 317 33 12596 4.816365548226747 1.0 0.7478209693865007 57.87487464787486
161 GOTERM_BP_FAT GO:0010909~positive regulation of heparan sulfate proteoglycan biosynthetic process 2 0.04153686396677051 0.049547226408451835 TCF7L2, CTNNB1 317 2 12596 39.73501577287066 1.0 0.7467624097666565 58.25973349969453
162 GOTERM_BP_FAT GO:0010908~regulation of heparan sulfate proteoglycan biosynthetic process 2 0.04153686396677051 0.049547226408451835 TCF7L2, CTNNB1 317 2 12596 39.73501577287066 1.0 0.7467624097666565 58.25973349969453
163 GOTERM_CC_FAT GO:0070369~beta-catenin-TCF7L2 complex 2 0.04153686396677051 0.05070745159372354 TCF7L2, CTNNB1 303 2 11759 38.80858085808581 0.9999999717105833 0.5010408861522672 50.67621471639776
164 GOTERM_CC_FAT GO:0031314~extrinsic to mitochondrial inner membrane 2 0.04153686396677051 0.05070745159372354 C3ORF31, C20ORF7 303 2 11759 38.80858085808581 0.9999999717105833 0.5010408861522672 50.67621471639776
165 SP_PIR_KEYWORDS ribosomal protein 9 0.1869158878504673 0.05117637200368516 RPS26, MRPS17, MRPL3, MRPL15, MRPL14, MRPS25, MRPS12, MRPL16, MRPS6 406 177 17699 2.21662352842949 0.9999999994243959 0.6933284060130538 52.003821824470855
166 PIR_SUPERFAMILY PIRSF008142:human SH3 binding glutamate-rich protein 2 0.04153686396677051 0.05185207613654086 SH3BGRL, SH3BGRL2 179 2 6776 37.85474860335196 0.9999909010881914 0.9969835597455594 49.17476577321915
167 UP_SEQ_FEATURE domain:EGF-like 5; calcium-binding 4 0.08307372793354102 0.05237857584915205 HMCN1, NPNT, EFEMP1, CELSR2 406 37 17662 4.7029689788310485 1.0 0.9965133108285761 57.92938552866288
168 UP_SEQ_FEATURE short sequence motif:Q motif 4 0.08307372793354102 0.05237857584915205 DDX17, DDX56, EIF4A1, DDX10 406 37 17662 4.7029689788310485 1.0 0.9965133108285761 57.92938552866288
169 GOTERM_BP_FAT GO:0009309~amine biosynthetic process 6 0.12461059190031153 0.05268047790461724 MTHFD1, GOT1, SRM, ASS1, ASNSD1, ETNK2 317 81 12596 2.9433345016941233 1.0 0.7638218811696865 60.56342332771594
170 GOTERM_BP_FAT GO:0040012~regulation of locomotion 10 0.20768431983385255 0.0530383421677684 PRR5, ARHGAP5, ERBB4, PTP4A1, JAK2, ARHGAP8, THBS1, ADORA1, IGFBP3, CXCL12, IGFBP5 317 192 12596 2.06953207150368 1.0 0.7616757212855878 60.81878172769765
171 GOTERM_BP_FAT GO:0009067~aspartate family amino acid biosynthetic process 3 0.06230529595015576 0.05312706187638507 MTHFD1, GOT1, ASNSD1 317 15 12596 7.947003154574132 1.0 0.7577855122526802 60.881847419625025
172 GOTERM_BP_FAT GO:0031175~neuron projection development 12 0.24922118380062305 0.05318847015870387 EPHA4, MYO6, PLA2G10, ADM, ERBB3, ANK3, CLU, JAK2, CNP, CELSR2, TOP2B, CXCL12 317 252 12596 1.8921436082319363 1.0 0.7537519684990772 60.92544300121051
173 GOTERM_BP_FAT GO:0016044~membrane organization 16 0.3322949117341641 0.05369707489166225 MYO6, HSP90AA1, DENND1A, COLEC12, ADORA1, TIMM8A, PPIF, DAB2, VAMP8, NME1, TXNDC5, PLSCR3, RIN2, LRP8, SNAP23, THBS1 317 378 12596 1.6819054295394988 1.0 0.7527312814484516 61.284761850694046
174 GOTERM_BP_FAT GO:0006412~translation 14 0.29075804776739356 0.054397695950354805 MRPS17, MRPL3, MRPS12, MRPS25, MRPS6, DARS2, IARS, RPS26, MRPL15, MRPL14, MRPL16, EIF4A1, FARSB, EIF2B3 317 315 12596 1.766000701016474 1.0 0.7529908487174795 61.774642662478385
175 GOTERM_BP_FAT GO:0051270~regulation of cell motion 10 0.20768431983385255 0.0551442126424675 PRR5, ARHGAP5, ERBB4, PTP4A1, JAK2, ARHGAP8, THBS1, ADORA1, IGFBP3, CXCL12, IGFBP5 317 193 12596 2.0588091074026247 1.0 0.7535428510121776 62.290186639188775
176 GOTERM_BP_FAT GO:0007005~mitochondrion organization 8 0.16614745586708204 0.05533521634809181 PPIF, HSP90AA1, TIMM17A, CLU, C3ORF31, C20ORF7, MYC, TIMM8A 317 136 12596 2.3373538689923916 1.0 0.750530362895744 62.42103759319142
177 SMART SM00211:TY 3 0.06230529595015576 0.055998967854419476 TACSTD2, IGFBP3, IGFBP5 197 17 8614 7.7163332338011354 0.9999410685285042 0.9610851140659282 50.4581250969362
178 SP_PIR_KEYWORDS kinetochore 5 0.10384215991692627 0.05606542707341393 PLK1, SPAG5, CENPA, ZWILCH, BUB3 406 63 17699 3.4598092110407386 0.9999999999289659 0.707674522930694 55.3464234409164
179 INTERPRO IPR001680:WD40 repeat 12 0.24922118380062305 0.056658420679608475 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, BCAS3, PRPF4, BUB3, GEMIN5 376 262 15425 1.8789589085593632 1.0 0.9983372578122935 58.95563410327892
180 GOTERM_BP_FAT GO:0030518~steroid hormone receptor signaling pathway 5 0.10384215991692627 0.057344714973009206 PGR, ESR1, FHL2, JAK2, CTNNB1 317 58 12596 3.425432394212988 1.0 0.7590107039019305 63.772014671910746
181 GOTERM_CC_FAT GO:0031410~cytoplasmic vesicle 24 0.4984423676012461 0.059107192159605186 RAB2A, HSP90AA1, MYO6, SGK3, CLU, SLC3A2, DENND1A, CNP, NPY1R, GAL, SYNGR3, LAMP2, DAB2, PLEKHF2, CCT4, STX12, CRISPLD2, MAP1LC3B, SLC2A1, CTSD, SYTL2, SNAP23, THBS1, RAB27B 303 633 11759 1.4714153879842962 0.9999999985465179 0.5428142548086261 56.28480734481506
182 UP_SEQ_FEATURE repeat:WD 4 11 0.2284527518172378 0.059206955341574885 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, PRPF4, BUB3, GEMIN5 406 247 17662 1.9373566542350573 1.0 0.9972177940181899 62.55157346405422
183 GOTERM_BP_FAT GO:0044271~nitrogen compound biosynthetic process 14 0.29075804776739356 0.06000379973032661 ASS1, SRM, DTYMK, ASNSD1, ATP5G1, MTHFD1, GOT1, ADM, NME1, ATP8B1, ETNK2, NQO1, FLAD1, PTS 317 320 12596 1.7384069400630917 1.0 0.770836634356973 65.48948774646801
184 GOTERM_CC_FAT GO:0005758~mitochondrial intermembrane space 4 0.08307372793354102 0.060026269179713744 PNPT1, CAT, CHCHD4, TIMM8A 303 35 11759 4.435266383781235 0.9999999989513046 0.5350230140575709 56.861213792662824
185 INTERPRO IPR014014:RNA helicase, DEAD-box type, Q motif 4 0.08307372793354102 0.060311190014499666 DDX17, DDX56, EIF4A1, DDX10 376 37 15425 4.435020126509488 1.0 0.9974504161433002 61.316240971733336
186 GOTERM_BP_FAT GO:0051100~negative regulation of binding 5 0.10384215991692627 0.06035413828351617 ID2, ID1, JAK2, ID3, CAT 317 59 12596 3.3673742180398865 1.0 0.7688660947949926 65.70996313935869
187 SP_PIR_KEYWORDS nadp 8 0.16614745586708204 0.06058708633686276 AKR1C3, MTHFD1, NNT, DHRS12, CAT, NQO1, WWOX, FDFT1 406 152 17699 2.2943997925849104 0.99999999998984 0.7179379551616164 58.24419626559586
188 GOTERM_BP_FAT GO:0007422~peripheral nervous system development 4 0.08307372793354102 0.06079159309719386 GSTM3, EGR3, ERBB3, PMP22 317 36 12596 4.415001752541184 1.0 0.7674279760089023 65.98340035176464
189 INTERPRO IPR017986:WD40 repeat, region 11 0.2284527518172378 0.06113469470257151 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, PRPF4, BUB3, GEMIN5 376 234 15425 1.928475631933079 1.0 0.9954064604954709 61.83060573315362
190 SP_PIR_KEYWORDS rna-binding 19 0.3946002076843198 0.06205063246491031 MRPS17, RBM24, SNRPD3, PNPT1, PNO1, MKI67IP, MBNL2, NXF1, AUH, SFRS7, ZFP36L2, DDX17, DDX56, METTL1, EIF4A1, SNRPC, DDX10, RBM28, GEMIN5 406 529 17699 1.5657435257526517 0.9999999999945968 0.7092901422772142 59.14406901253815
191 INTERPRO IPR000716:Thyroglobulin type-1 3 0.06230529595015576 0.06304459604703608 TACSTD2, IGFBP3, IGFBP5 376 17 15425 7.239518147684604 1.0 0.9932700306835047 62.99904184800552
192 GOTERM_BP_FAT GO:0031399~regulation of protein modification process 13 0.2699896157840083 0.06334756789299707 PTPLAD1, ADORA1, IL20, PSMB5, CCNB1, PSMF1, PSMD12, PLK1, PSMD3, JAK2, ANAPC7, IGFBP3, BUB3 317 291 12596 1.7751037974134662 1.0 0.777857639372783 67.54043984413478
193 GOTERM_BP_FAT GO:0008202~steroid metabolic process 10 0.20768431983385255 0.06358410659293362 DHRS2, UGT2B17, MBTPS2, ADM, ATP8B1, CAT, UGT2B15, ABCG1, WWOX, FDFT1 317 199 12596 1.9967344609482747 1.0 0.7753206828680957 67.68108848124157
194 GOTERM_CC_FAT GO:0005813~centrosome 11 0.2284527518172378 0.06377795337444189 CCNB1, LITAF, PLK1, NME1, FAM110C, RANBP1, AURKA, RUVBL1, CEP55, DCTN4, CTNNB1 303 224 11759 1.9057785242809995 0.9999999997242341 0.5443926374361975 59.141854599111056
195 GOTERM_MF_FAT GO:0015020~glucuronosyltransferase activity 3 0.06230529595015576 0.06576587438074508 UGT2B17, CHSY1, UGT2B15 284 18 12042 7.066901408450704 1.0 0.9989971030702931 63.46034911141201
196 INTERPRO IPR019781:WD40 repeat, subgroup 11 0.2284527518172378 0.06692872285796972 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, PRPF4, BUB3, GEMIN5 376 238 15425 1.8960642767745397 1.0 0.9920657207637819 65.27289994056298
197 UP_SEQ_FEATURE binding site:Aspartate 2 0.04153686396677051 0.06723009690855708 GOT1, ASS1 406 3 17662 29.001642036124796 1.0 0.9979585784667891 67.37327320770538
198 UP_SEQ_FEATURE region of interest:Sufficient for nucleolar localization 2 0.04153686396677051 0.06723009690855708 WDR12, BOP1 406 3 17662 29.001642036124796 1.0 0.9979585784667891 67.37327320770538
199 GOTERM_BP_FAT GO:0006916~anti-apoptosis 10 0.20768431983385255 0.07026218119336548 SOCS2, SGK3, TXNDC5, CLU, ESR1, GLO1, FOXC1, THBS1, MYC, TCF7L2 317 203 12596 1.957389939550279 1.0 0.8054640215309694 71.42307896207865
200 GOTERM_MF_FAT GO:0030674~protein binding, bridging 6 0.12461059190031153 0.07039433987386781 SH3BGRL, SOCS2, EPS8, FKBP4, GRB14, BLNK 284 94 12042 2.7064728798321847 1.0 0.9982542097474582 66.04977129369665
201 SP_PIR_KEYWORDS ubl conjugation 20 0.4153686396677051 0.07109587143317246 RNF144B, YPEL3, SLC3A2, ESR1, AURKA, CCDC138, SLC7A5, TCF7L2, CTNNB1, PGR, CCNB1, CDCA8, NME1, CENPA, ANK3, CDCA5, UBE2S, HIST1H3H, WWOX, BUB3 406 576 17699 1.513666529830323 0.9999999999998933 0.742739410847671 64.3180508074028
202 GOTERM_CC_FAT GO:0043228~non-membrane-bounded organelle 75 1.557632398753894 0.07143849371434532 LIMA1, LYAR, FAM110C, SNRPD3, PDLIM3, MKI67IP, AURKA, ADORA1, CTNNB1, WDR75, CDCA8, PBXIP1, ANK3, MAP1LC3B, LRRC59, TUBB6, RANBP1, TOP2B, MYC, CDCA5, IMP4, MYO6, MRPL3, RBL2, EMG1, PSD3, MRPS6, DCTN4, PGM5, NAV2, SPAG5, NME1, NLE1, FOXC1, RUVBL1, MRPS17, POLR2F, LITAF, ERBB4, HAX1, MRPS12, FKBP4, YPEL2, YPEL3, NOC3L, EPB41L4A, FHL2, BOP1, MYBL1, CEP55, RPS26, MRPL15, CENPA, MRPL14, MRPL16, WDR12, NPM3, NAT10, APPBP2, ZWILCH, RBM28, BUB3, MYO1B, MRPS25, PNO1, CCNB1, CORO1B, DDX56, ID2, EPS8, PLK1, PTP4A1, JAK2, HIST1H3H, RPP40 303 2460 11759 1.183188440795299 0.9999999999822676 0.5741390830311865 63.45593269280254
203 GOTERM_CC_FAT GO:0043232~intracellular non-membrane-bounded organelle 75 1.557632398753894 0.07143849371434532 LIMA1, LYAR, FAM110C, SNRPD3, PDLIM3, MKI67IP, AURKA, ADORA1, CTNNB1, WDR75, CDCA8, PBXIP1, ANK3, MAP1LC3B, LRRC59, TUBB6, RANBP1, TOP2B, MYC, CDCA5, IMP4, MYO6, MRPL3, RBL2, EMG1, PSD3, MRPS6, DCTN4, PGM5, NAV2, SPAG5, NME1, NLE1, FOXC1, RUVBL1, MRPS17, POLR2F, LITAF, ERBB4, HAX1, MRPS12, FKBP4, YPEL2, YPEL3, NOC3L, EPB41L4A, FHL2, BOP1, MYBL1, CEP55, RPS26, MRPL15, CENPA, MRPL14, MRPL16, WDR12, NPM3, NAT10, APPBP2, ZWILCH, RBM28, BUB3, MYO1B, MRPS25, PNO1, CCNB1, CORO1B, DDX56, ID2, EPS8, PLK1, PTP4A1, JAK2, HIST1H3H, RPP40 303 2460 11759 1.183188440795299 0.9999999999822676 0.5741390830311865 63.45593269280254
204 INTERPRO IPR019775:WD40 repeat, conserved site 12 0.24922118380062305 0.07147483583289199 WDR75, CORO1B, CORO2A, WDR4, NLE1, WDR12, TLE1, BOP1, BCAS3, PRPF4, BUB3, GEMIN5 376 273 15425 1.8032499415478138 1.0 0.9913144884652278 67.76827484168592
205 GOTERM_MF_FAT GO:0004714~transmembrane receptor protein tyrosine kinase activity 5 0.10384215991692627 0.07251487952597366 EPHA4, RET, ERBB4, ERBB3, CRIM1 284 67 12042 3.1642842127391213 1.0 0.996754798666449 67.17803335708818
206 GOTERM_MF_FAT GO:0060090~molecular adaptor activity 5 0.10384215991692627 0.07251487952597366 SH3BGRL, SOCS2, EPS8, GRB14, BLNK 284 67 12042 3.1642842127391213 1.0 0.996754798666449 67.17803335708818
207 GOTERM_BP_FAT GO:0000470~maturation of LSU-rRNA 2 0.04153686396677051 0.07339533474859315 WDR12, BOP1 317 3 12596 26.490010515247107 1.0 0.8162100192708674 73.03440916702593
208 GOTERM_BP_FAT GO:0000463~maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2 0.04153686396677051 0.07339533474859315 WDR12, BOP1 317 3 12596 26.490010515247107 1.0 0.8162100192708674 73.03440916702593
209 GOTERM_BP_FAT GO:0051176~positive regulation of sulfur metabolic process 2 0.04153686396677051 0.07339533474859315 TCF7L2, CTNNB1 317 3 12596 26.490010515247107 1.0 0.8162100192708674 73.03440916702593
210 GOTERM_CC_FAT GO:0015935~small ribosomal subunit 5 0.10384215991692627 0.0747240552695666 RPS26, MRPS17, MRPS25, MRPS12, MRPS6 303 62 11759 3.1297242627488555 0.9999999999945725 0.578801492823861 65.1735442404278
211 SMART SM00121:IB 3 0.06230529595015576 0.07486401532498171 IGFBP3, CRIM1, IGFBP5 197 20 8614 6.558883248730965 0.9999980557953149 0.9626590385133938 61.26314876777088
212 GOTERM_CC_FAT GO:0070545~PeBoW complex 2 0.04153686396677051 0.0750917630330909 WDR12, BOP1 303 3 11759 25.872387238723874 0.9999999999952472 0.5687389231311895 65.3610466746408
213 GOTERM_BP_FAT GO:0006364~rRNA processing 6 0.12461059190031153 0.0756785363916411 DDX56, EMG1, WDR12, NPM3, BOP1, IMP4 317 90 12596 2.649001051524711 1.0 0.8226390626593285 74.15429573628015
214 UP_SEQ_FEATURE domain:IGFBP N-terminal 3 0.06230529595015576 0.07597418937108522 IGFBP3, CRIM1, IGFBP5 406 20 17662 6.525369458128078 1.0 0.9985410642007156 71.96211367311416
215 SP_PIR_KEYWORDS LIM domain 5 0.10384215991692627 0.07642954038403478 PRICKLE4, LIMA1, FHL1, PDLIM3, FHL2 406 70 17699 3.1138282899366647 0.9999999999999897 0.7534117774287536 67.07669850878793
216 GOTERM_BP_FAT GO:0031400~negative regulation of protein modification process 7 0.14537902388369678 0.07647963778743302 PSMB5, PSMF1, PSMD12, PSMD3, ANAPC7, IGFBP3, BUB3 317 118 12596 2.3571619526279206 1.0 0.8226478645813364 74.53673711667301
217 GOTERM_BP_FAT GO:0034622~cellular macromolecular complex assembly 13 0.2699896157840083 0.07716891832960607 HSP90AA1, SNRPD3, FKBP4, C20ORF7, TSPYL4, CENPA, PRMT5, TUBB6, SNRPC, GEMIN6, ZNHIT6, HIST1H3H, GEMIN5 317 301 12596 1.71613024932664 1.0 0.8221965945664167 74.86152369488484
218 GOTERM_BP_FAT GO:0032268~regulation of cellular protein metabolic process 18 0.3738317757009346 0.0806017241046966 PLA2G10, PTPLAD1, ADORA1, IL20, PSMB5, CCNB1, PSMF1, PSMD12, PLK1, PSMD3, JAK2, ANAPC7, THBS1, EIF2B3, IGFBP3, DNAJC1, BUB3, IGFBP5 317 466 12596 1.5348289354327722 1.0 0.8327051161875013 76.42176708432227
219 GOTERM_BP_FAT GO:0000904~cell morphogenesis involved in differentiation 11 0.2284527518172378 0.08066981572020238 EPHA4, DAB2, PLA2G10, ERBB3, ANK3, JAK2, CNP, CELSR2, TOP2B, CXCL12, CTNNB1 317 240 12596 1.8211882229232386 1.0 0.8297922393632984 76.45177236749447
220 SMART SM00132:LIM 5 0.10384215991692627 0.08111073873551117 PRICKLE4, LIMA1, FHL1, PDLIM3, FHL2 197 72 8614 3.0365200225606315 0.9999993813047775 0.9426814292703194 64.33326866434123
221 SP_PIR_KEYWORDS Signal-anchor 15 0.3115264797507788 0.08186107952587367 FUT8, SLC3A2, COLEC12, TMPRSS3, CANT1, MANEAL, B3GNT5, ST8SIA4, LRRC59, B3GALNT2, CLEC2D, SPCS3, CREB3L4, CHSY1, GALNT12 406 404 17699 1.6185741111056922 0.999999999999999 0.7633648733379841 69.6814138449932
222 GOTERM_BP_FAT GO:0048858~cell projection morphogenesis 11 0.2284527518172378 0.08247942203817202 EPHA4, PLA2G10, ADM, ERBB3, ANK3, CLU, JAK2, CNP, CELSR2, TOP2B, CXCL12 317 241 12596 1.8136314253177481 1.0 0.8335963772248779 77.23614081789346
223 UP_SEQ_FEATURE repeat:WD 5 10 0.20768431983385255 0.08352237273109168 WDR75, CORO1B, CORO2A, NLE1, WDR12, TLE1, BOP1, PRPF4, BUB3, GEMIN5 406 230 17662 1.8914114371385737 1.0 0.9988023404379672 75.42931344624063
224 GOTERM_BP_FAT GO:0046883~regulation of hormone secretion 5 0.10384215991692627 0.08368744456600033 GPR109B, JAK2, NPY1R, ADORA1, TCF7L2 317 66 12596 3.010228467641717 1.0 0.8350339465005248 77.74598633724658
225 INTERPRO IPR000867:Insulin-like growth factor-binding protein, IGFBP 3 0.06230529595015576 0.08402055003041867 IGFBP3, CRIM1, IGFBP5 376 20 15425 6.153590425531915 1.0 0.9943982177298983 73.81317904369817
226 GOTERM_MF_FAT GO:0008047~enzyme activator activity 13 0.2699896157840083 0.08474229865636124 RAP1GAP, ERBB3, PTPLAD1, CTSA, FGF13, PRR5, ARHGAP5, SGSM2, RIN2, RANBP1, ARHGAP8, AHSA1, IGFBP3, DNAJC1 284 327 12042 1.685682904768058 1.0 0.9975009812288564 73.03081919940348
227 GOTERM_BP_FAT GO:0006396~RNA processing 20 0.4153686396677051 0.08525671415344027 POLR2F, EMG1, SNRPD3, PNPT1, BOP1, PRPF4, SFRS7, DDX17, DDX56, METTL1, PRMT5, WDR4, NPM3, WDR12, SNRPC, GEMIN6, RBM28, IMP4, RPP40, GEMIN5 317 539 12596 1.4743976168041062 1.0 0.8377486282906571 78.39224695444797
228 SP_PIR_KEYWORDS phosphoprotein 179 3.717549325025961 0.08526029860947158 PITPNA, FAM110C, CNP, AURKA, SLC7A5, CTNNB1, C14ORF4, PGR, WDR75, SFRS7, DAB2, SLC16A1, DDX17, CDCA8, FAM171B, GOT1, ANK3, GATA3, LRRC59, SLC2A1, DDX10, DNAJC2, CDCA5, WWOX, DNAJC1, DEPDC6, PTPRJ, F11R, RET, MYO6, RBL2, EMG1, PSD3, COLEC12, CCDC138, TIMM8A, PGM5, SPAG5, NME1, VAMP8, TACSTD2, NAV2, HSPB8, IGSF3, TFPI, NLE1, SNRPC, FLAD1, ZNHIT6, GRB14, MRPS17, COBL, IL1R1, PPME1, ERBB4, ASS1, ERBB3, PTPLAD1, PNPT1, CLU, NOC3L, UBA5, BOP1, STK17A, CCNG2, RPS26, PRR5, FAM102B, STX12, METTL1, C2ORF55, PTPLA, RHOBTB1, NPM3, NAT10, BLNK, SASH1, ZC3H15, PTPN18, PHB, RHBDF1, DENND1A, PPFIBP2, EHBP1, TPD52L1, ACPP, CORO1B, EPHA4, DDX56, EPS8, PLK1, LASS2, WDR4, GPATCH4, SYTL2, FAM84A, FAM84B, PDZK1, HIST1H3H, FABP5, LIMA1, SLC20A2, LYAR, MKI67IP, DPH2, PAWR, SLC26A2, RTN2, MTHFD1, ARHGAP5, PBXIP1, SRPR, ATP8B1, TUBB6, CEACAM6, RANBP1, SEPP1, CAT, TOP2B, ARHGAP8, MYC, HSP90AA1, SSBP2, SGK3, ESR1, SLC3A2, TLE1, RFTN1, GAL, C1QBP, EIF4A1, FARSB, RIN2, SERPINB1, FOXC1, LTV1, UBE2T, POLR2F, ECH1, RAP1GAP, FKBP4, EPB41L4A, FHL2, CEP55, TCF7L2, IARS, C12ORF45, PSMF1, TSC22D3, MORC4, CENPA, SNAP23, DDIT4L, BCAS3, PTS, GEMIN6, RBM28, BUB3, CRIM1, ETFA, GEMIN5, COBLL1, BCAS1, RBM24, SLC12A2, RRP15, ARMC10, PNO1, DGKH, NPY1R, NPR3, CCNB1, PLEKHF2, ID1, TMEM164, PLSCR3, JAK2, LRP8, IGFBP3, ABCC5 406 7171 17699 1.0881681347903056 0.9999999999999998 0.763941325297534 71.2127730069467
229 GOTERM_CC_FAT GO:0031982~vesicle 24 0.4984423676012461 0.08630372161083126 RAB2A, HSP90AA1, MYO6, SGK3, CLU, SLC3A2, DENND1A, CNP, NPY1R, GAL, SYNGR3, LAMP2, DAB2, PLEKHF2, CCT4, STX12, CRISPLD2, MAP1LC3B, SLC2A1, CTSD, SYTL2, SNAP23, THBS1, RAB27B 303 661 11759 1.4090861431075028 0.9999999999999192 0.6101752834927674 70.64880663206989
230 KEGG_PATHWAY hsa04110:Cell cycle 7 0.14537902388369678 0.08653384731365792 CCNB1, RBL2, PLK1, ANAPC7, GADD45B, MYC, BUB3 120 122 4719 2.2563524590163935 0.9999950627846789 0.9131646790913583 65.39252575720927
231 GOTERM_BP_FAT GO:0006839~mitochondrial transport 5 0.10384215991692627 0.08733537746676182 PPIF, HSP90AA1, TIMM17A, C3ORF31, TIMM8A 317 67 12596 2.9652996845425865 1.0 0.8421638818173915 79.22110371744463
232 GOTERM_CC_FAT GO:0031970~organelle envelope lumen 4 0.08307372793354102 0.0875640113745962 PNPT1, CAT, CHCHD4, TIMM8A 303 41 11759 3.7862030105449573 0.999999999999949 0.6044511604964797 71.19391286155042
233 KEGG_PATHWAY hsa00240:Pyrimidine metabolism 6 0.12461059190031153 0.08759345106997281 POLR2F, POLR3H, NME1, PNPT1, DTYMK, CANT1 120 94 4719 2.5101063829787233 0.9999957788268533 0.872872688931561 65.8602463576045
234 GOTERM_BP_FAT GO:0001649~osteoblast differentiation 4 0.08307372793354102 0.08776878882945893 FHL2, IGFBP3, WWOX, IGFBP5 317 42 12596 3.7842872164638726 1.0 0.840742995368493 79.39010867246087
235 GOTERM_BP_FAT GO:0034470~ncRNA processing 9 0.1869158878504673 0.08795885798094556 DDX56, EMG1, METTL1, WDR4, WDR12, NPM3, BOP1, IMP4, RPP40 317 182 12596 1.964918362394703 1.0 0.8384873551045449 79.46381535174984
236 SMART SM00428:H3 2 0.04153686396677051 0.08796990216586997 CENPA, HIST1H3H 197 4 8614 21.862944162436545 0.9999998255986488 0.9252533658831251 67.44598716415169
237 GOTERM_BP_FAT GO:0002685~regulation of leukocyte migration 3 0.06230529595015576 0.08864257549883234 THBS1, ADORA1, CXCL12 317 20 12596 5.960252365930599 1.0 0.8379746164437184 79.7269057196236
238 SP_PIR_KEYWORDS serine proteinase inhibitor 3 0.06230529595015576 0.08935996268944174 SERPINA3, TFPI, SERPINB1 406 22 17699 5.944581280788177 1.0 0.7673262946595989 72.9640932419318
239 GOTERM_BP_FAT GO:0065003~macromolecular complex assembly 23 0.47767393561786087 0.08979311920146946 POLR2F, HSP90AA1, SNRPD3, FKBP4, DGKH, MKI67IP, COLEC12, C20ORF7, TSPYL4, CTNNB1, VAMP8, CENPA, PRMT5, GPX3, TUBB6, SNRPC, CAT, ZNHIT6, GEMIN6, SLC1A1, MYC, HIST1H3H, GEMIN5 317 646 12596 1.4147141838638162 1.0 0.8390821724980984 80.16247564301034
240 GOTERM_BP_FAT GO:0000398~nuclear mRNA splicing, via spliceosome 8 0.16614745586708204 0.09062184711061548 SFRS7, POLR2F, PRMT5, SNRPD3, SNRPC, GEMIN6, PRPF4, GEMIN5 317 153 12596 2.0776478835487926 1.0 0.839074333890355 80.47073599698196
241 GOTERM_BP_FAT GO:0000377~RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 8 0.16614745586708204 0.09062184711061548 SFRS7, POLR2F, PRMT5, SNRPD3, SNRPC, GEMIN6, PRPF4, GEMIN5 317 153 12596 2.0776478835487926 1.0 0.839074333890355 80.47073599698196
242 GOTERM_BP_FAT GO:0000375~RNA splicing, via transesterification reactions 8 0.16614745586708204 0.09062184711061548 SFRS7, POLR2F, PRMT5, SNRPD3, SNRPC, GEMIN6, PRPF4, GEMIN5 317 153 12596 2.0776478835487926 1.0 0.839074333890355 80.47073599698196
243 KEGG_PATHWAY hsa04115:p53 signaling pathway 5 0.10384215991692627 0.09147952665668836 CCNB1, GADD45B, THBS1, IGFBP3, CCNG2 120 68 4719 2.891544117647059 0.999997627605013 0.8427990068771256 67.52654961556445
244 BIOCARTA h_mta3Pathway:Downregulated of MTA-3 in ER-negative Breast Tumors 3 0.06230529595015576 0.09227110276436244 ESR1, CTSD, PDZK1 50 15 1418 5.672000000000001 0.999676136961411 0.982003804885782 64.53771011912981
245 GOTERM_MF_FAT GO:0047485~protein N-terminus binding 5 0.10384215991692627 0.09260811945502158 PGR, HAX1, ESR1, DCN, DCTN4 284 73 12042 2.9042060582674125 1.0 0.9973102697360594 76.26482706910731
246 KEGG_PATHWAY hsa03050:Proteasome 4 0.08307372793354102 0.09324640408194752 PSMB5, PSMF1, PSMD12, PSMD3 120 43 4719 3.6581395348837207 0.999998175878833 0.8082957635697237 68.25927524042407
247 INTERPRO IPR000164:Histone H3 2 0.04153686396677051 0.09376444118211757 CENPA, HIST1H3H 376 4 15425 20.511968085106382 1.0 0.9954880024061731 77.75819943805821
248 INTERPRO IPR016245:Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK 2 0.04153686396677051 0.09376444118211757 ERBB4, ERBB3 376 4 15425 20.511968085106382 1.0 0.9954880024061731 77.75819943805821
249 INTERPRO IPR007482:Protein-tyrosine phosphatase-like, PTPLA 2 0.04153686396677051 0.09376444118211757 PTPLAD1, PTPLA 376 4 15425 20.511968085106382 1.0 0.9954880024061731 77.75819943805821
250 INTERPRO IPR006993:SH3-binding, glutamic acid-rich protein 2 0.04153686396677051 0.09376444118211757 SH3BGRL, SH3BGRL2 376 4 15425 20.511968085106382 1.0 0.9954880024061731 77.75819943805821
251 GOTERM_BP_FAT GO:0044093~positive regulation of molecular function 21 0.43613707165109034 0.09482343956269823 EFNA1, PTPLAD1, DGKH, NPR3, ADORA1, GCLM, SYNGR3, PSMB5, CCNB1, PSMF1, PSMD12, PLK1, NME1, PSMD3, JAK2, LRP8, CAT, ANAPC7, GADD45B, THBS1, MYC 317 581 12596 1.4362053893808675 1.0 0.850075582946088 81.96539632088789
252 SMART SM00356:ZnF_C3H1 4 0.08307372793354102 0.09538238996301751 ZFP36L2, ZC3H15, TIPARP, MBNL2 197 48 8614 3.6438240270727578 0.9999999560871734 0.9110918389369811 70.52798905317319
253 GOTERM_BP_FAT GO:0022403~cell cycle phase 16 0.3322949117341641 0.09609786820755639 AURKA, TPD52L1, CEP55, CCNG2, CCNB1, CDCA8, SPAG5, PLK1, ID4, RANBP1, ANAPC7, RUVBL1, ZWILCH, DNAJC2, CDCA5, BUB3 317 411 12596 1.5468619278976414 1.0 0.851371502424794 82.39701687194064
254 SP_PIR_KEYWORDS amyloid 3 0.06230529595015576 0.09644232013931607 TACSTD2, TGFBI, SERPINA3 406 23 17699 5.686121225101735 1.0 0.7815569540800467 75.7584969918613
255 GOTERM_BP_FAT GO:0042762~regulation of sulfur metabolic process 2 0.04153686396677051 0.09664690897467512 TCF7L2, CTNNB1 317 4 12596 19.86750788643533 1.0 0.8504084042438278 82.57994978523911
256 GOTERM_BP_FAT GO:0014912~negative regulation of smooth muscle cell migration 2 0.04153686396677051 0.09664690897467512 IGFBP3, IGFBP5 317 4 12596 19.86750788643533 1.0 0.8504084042438278 82.57994978523911
257 INTERPRO IPR001781:Zinc finger, LIM-type 5 0.10384215991692627 0.09800762659507971 PRICKLE4, LIMA1, FHL1, PDLIM3, FHL2 376 72 15425 2.8488844562647753 1.0 0.9949138787128781 79.29616466171514
258 KEGG_PATHWAY hsa00561:Glycerolipid metabolism 4 0.08307372793354102 0.09831233043035789 DGAT2, GLA, ALDH1B1, DGKH 120 44 4719 3.5749999999999997 0.9999991437951977 0.7882409586793104 70.27709635818513
259 GOTERM_CC_FAT GO:0030686~90S preribosome 2 0.04153686396677051 0.09885173985918513 WDR12, BOP1 303 4 11759 19.404290429042906 0.9999999999999992 0.6403006789822472 75.67460535321248
260 GOTERM_CC_FAT GO:0031312~extrinsic to organelle membrane 2 0.04153686396677051 0.09885173985918513 C3ORF31, C20ORF7 303 4 11759 19.404290429042906 0.9999999999999992 0.6403006789822472 75.67460535321248
261 GOTERM_CC_FAT GO:0016942~insulin-like growth factor binding protein complex 2 0.04153686396677051 0.09885173985918513 IGFBP3, IGFBP5 303 4 11759 19.404290429042906 0.9999999999999992 0.6403006789822472 75.67460535321248
262 GOTERM_MF_FAT GO:0003723~RNA binding 23 0.47767393561786087 0.09895331713561223 MRPS17, RBM24, MRPL3, PNPT1, PNO1, MRPS6, MBNL2, MKI67IP, NXF1, AUH, SFRS7, ZFP36L2, RPS26, DDX17, DDX56, METTL1, EIF4A1, MRPL16, FARSB, SNRPC, DDX10, RBM28, GEMIN5 284 698 12042 1.3971810807538643 1.0 0.9968764710177949 78.60609834358826
263 SP_PIR_KEYWORDS atp-binding 38 0.7892004153686396 0.09920775512966237 ERBB4, ASS1, ERBB3, DTYMK, UBA5, AURKA, STK17A, ACSF2, MTHFD1, IARS, DDX17, ATP8B1, ETNK2, NAT10, DDX10, TOP2B, RET, HSP90AA1, MYO6, SGK3, MYO1B, DGKH, DARS2, ABCG1, EPHA4, DDX56, CCT4, NME1, PLK1, NAV2, EIF4A1, FARSB, JAK2, RUVBL1, FLAD1, UBE2S, ABCC5, UBE2T 406 1301 17699 1.2732948887365914 1.0 0.7793632721653414 76.77489305480671
264 GOTERM_BP_FAT GO:0010605~negative regulation of macromolecule metabolic process 25 0.5192107995846313 0.0998830153066572 PAWR, CTNNB1, PSMB5, RPS26, PSMF1, PBXIP1, ATP8B1, PSMD3, THBS1, MYC, EIF2B3, BUB3, DNAJC1, PHB, TLE1, PKIA, MXD4, ID2, PSMD12, ID1, ID4, ANAPC7, ID3, IGFBP3, IGFBP5 317 725 12596 1.3701729576851953 1.0 0.8575428069856033 83.62231771858487
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