Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | GO|GO:0030177 |
Enrichment Score (ES) | -0.7628027 |
Normalized Enrichment Score (NES) | -1.6867002 |
Nominal p-value | 0.0 |
FDR q-value | 0.15976378 |
FWER p-Value | 0.965 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 23499 | MACF1 (microtubule-actin crosslinking factor 1) | 2216 | 16.993 | -0.0841 | No | ||
2 | 857 | "CAV1 (caveolin 1, caveolae protein, 22kDa)" | 3406 | 9.137 | -0.1292 | No | ||
3 | 1855 | "DVL1 (dishevelled, dsh homolog 1 (Drosophila))" | 3544 | 8.605 | -0.1232 | No | ||
4 | 65981 | CAPRIN2 (caprin family member 2) | 3728 | 7.818 | -0.1206 | No | ||
5 | 54795 | "TRPM4 (transient receptor potential cation channel, subfamily M, member 4)" | 4867 | 4.316 | -0.1703 | No | ||
6 | 54361 | "WNT4 (wingless-type MMTV integration site family, member 4)" | 5623 | 2.881 | -0.2033 | No | ||
7 | 2263 | FGFR2 (fibroblast growth factor receptor 2) | 6001 | 2.374 | -0.2183 | No | ||
8 | 3087 | HHEX (hematopoietically expressed homeobox) | 6095 | 2.232 | -0.2196 | No | ||
9 | 79971 | GPR177 (G protein-coupled receptor 177) | 6493 | 1.786 | -0.2365 | No | ||
10 | 6422 | SFRP1 (secreted frizzled-related protein 1) | 6696 | 1.594 | -0.2441 | No | ||
11 | 7482 | "WNT2B (wingless-type MMTV integration site family, member 2B)" | 8184 | 0.658 | -0.3165 | No | ||
12 | 7097 | TLR2 (toll-like receptor 2) | 8386 | 0.583 | -0.3255 | No | ||
13 | 6299 | SALL1 (sal-like 1 (Drosophila)) | 8649 | 0.497 | -0.3377 | No | ||
14 | 4040 | LRP6 (low density lipoprotein receptor-related protein 6) | 10453 | 0.025 | -0.4265 | No | ||
15 | 284654 | RSPO1 (R-spondin homolog (Xenopus laevis)) | 12085 | -0.344 | -0.5064 | No | ||
16 | 6424 | SFRP4 (secreted frizzled-related protein 4) | 12681 | -0.506 | -0.5350 | No | ||
17 | 7472 | WNT2 (wingless-type MMTV integration site family member 2) | 12752 | -0.529 | -0.5377 | No | ||
18 | 27123 | DKK2 (dickkopf homolog 2 (Xenopus laevis)) | 12862 | -0.564 | -0.5422 | No | ||
19 | 6423 | SFRP2 (secreted frizzled-related protein 2) | 13706 | -0.856 | -0.5825 | No | ||
20 | 54764 | "ZRANB1 (zinc finger, RAN-binding domain containing 1)" | 13837 | -0.915 | -0.5876 | No | ||
21 | 7476 | "WNT7A (wingless-type MMTV integration site family, member 7A)" | 13938 | -0.966 | -0.5911 | No | ||
22 | 27185 | DISC1 (disrupted in schizophrenia 1) | 14319 | -1.142 | -0.6081 | No | ||
23 | 1277 | "COL1A1 (collagen, type I, alpha 1)" | 15634 | -2.082 | -0.6698 | No | ||
24 | 441478 | NRARP (Notch-regulated ankyrin repeat protein) | 15635 | -2.084 | -0.6667 | No | ||
25 | 85458 | DIXDC1 (DIX domain containing 1) | 16456 | -3.143 | -0.7025 | No | ||
26 | 8658 | "TNKS (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase)" | 16951 | -4.120 | -0.7207 | No | ||
27 | 4790 | NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) | 17493 | -5.614 | -0.7391 | No | ||
28 | 5494 | "PPM1A (protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform)" | 17598 | -6.003 | -0.7353 | No | ||
29 | 81847 | RNF146 (ring finger protein 146) | 17727 | -6.565 | -0.7319 | No | ||
30 | 9736 | USP34 (ubiquitin specific peptidase 34) | 18355 | -9.931 | -0.7481 | Yes | ||
31 | 4088 | SMAD3 (SMAD family member 3) | 18573 | -11.772 | -0.7414 | Yes | ||
32 | 80351 | "TNKS2 (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2)" | 18583 | -11.868 | -0.7242 | Yes | ||
33 | 1453 | "CSNK1D (casein kinase 1, delta)" | 18599 | -12.019 | -0.7072 | Yes | ||
34 | 6497 | SKI (v-ski sarcoma viral oncogene homolog (avian)) | 18818 | -14.221 | -0.6969 | Yes | ||
35 | 51366 | UBR5 (ubiquitin protein ligase E3 component n-recognin 5) | 19390 | -25.318 | -0.6875 | Yes | ||
36 | 6659 | SOX4 (SRY (sex determining region Y)-box 4) | 19584 | -30.987 | -0.6511 | Yes | ||
37 | 3611 | ILK (integrin-linked kinase) | 19688 | -36.185 | -0.6026 | Yes | ||
38 | 1601 | "DAB2 (disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila))" | 19933 | -54.755 | -0.5336 | Yes | ||
39 | 3728 | JUP (junction plakoglobin) | 19987 | -61.273 | -0.4455 | Yes | ||
40 | 25805 | BAMBI (BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)) | 20317 | -312.036 | 0.0004 | Yes |