Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0043900
Enrichment Score (ES)-0.7084739
Normalized Enrichment Score (NES)-1.6686215
Nominal p-value0.0028985508
FDR q-value0.17754406
FWER p-Value0.991
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0043900   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
11175"AP2S1 (adaptor-related protein complex 2, sigma 1 subunit)"177721.343-0.0682No
2162"AP1B1 (adaptor-related protein complex 1, beta 1 subunit)"202018.565-0.0632No
38905"AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)"224016.745-0.0587No
46895TARBP2 (TAR (HIV-1) RNA binding protein 2)225116.637-0.0440No
5163"AP2B1 (adaptor-related protein complex 2, beta 1 subunit)"251114.197-0.0438No
6161"AP2A2 (adaptor-related protein complex 2, alpha 2 subunit)"254413.921-0.0326No
74277MICB (MHC class I polypeptide-related sequence B)268812.937-0.0279No
88907"AP1M1 (adaptor-related protein complex 1, mu 1 subunit)"314510.205-0.0410No
9130340"AP1S3 (adaptor-related protein complex 1, sigma 3 subunit)"37747.615-0.0651No
1051191HERC5 (hect domain and RLD 5)41406.303-0.0773No
112534"FYN (FYN oncogene related to SRC, FGR, YES)"42445.992-0.0769No
127187TRAF3 (TNF receptor-associated factor 3)43285.691-0.0758No
13255520ELMOD2 (ELMO/CED-12 domain containing 2)45145.198-0.0802No
141174"AP1S1 (adaptor-related protein complex 1, sigma 1 subunit)"46824.756-0.0841No
15160"AP2A1 (adaptor-related protein complex 2, alpha 1 subunit)"46984.725-0.0805No
162208"FCER2 (Fc fragment of IgE, low affinity II, receptor for (CD23))"51163.777-0.0976No
174843"NOS2A (nitric oxide synthase 2A (inducible, hepatocytes))"55023.060-0.1138No
1860489"APOBEC3G (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G)"58202.589-0.1271No
192150F2RL1 (coagulation factor II (thrombin) receptor-like 1)59232.465-0.1299No
20222537HS3ST5 (heparan sulfate (glucosamine) 3-O-sulfotransferase 5)59842.392-0.1307No
21820CAMP (cathelicidin antimicrobial peptide)69491.377-0.1770No
22149233IL23R (interleukin 23 receptor)72281.174-0.1896No
23340061TMEM173 (transmembrane protein 173)73611.090-0.1951No
2483737ITCH (itchy E3 ubiquitin protein ligase homolog (mouse))75900.949-0.2055No
253932LCK (lymphocyte-specific protein tyrosine kinase)86020.511-0.2550No
2654476RNF216 (ring finger protein 216)98320.174-0.3154No
273458"IFNG (interferon, gamma)"98350.174-0.3154No
28919CD247 (CD247 molecule)98650.167-0.3167No
293593"IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))"11374-0.185-0.3909No
30940CD28 (CD28 molecule)12034-0.333-0.4231No
314153"MBL2 (mannose-binding lectin (protein C) 2, soluble (opsonic defect))"12147-0.357-0.4283No
325027"P2RX7 (purinergic receptor P2X, ligand-gated ion channel, 7)"12248-0.386-0.4329No
33920CD4 (CD4 molecule)12457-0.446-0.4428No
3455894"DEFB103A (defensin, beta 103A)"12657-0.500-0.4521No
35163702"IL28RA (interleukin 28 receptor, alpha (interferon, lambda receptor))"13920-0.961-0.5135No
361794DOCK2 (dedicator of cytokinesis 2)14135-1.064-0.5231No
37926CD8B (CD8b molecule)14383-1.176-0.5342No
389844ELMO1 (engulfment and cell motility 1)14392-1.178-0.5335No
397128"TNFAIP3 (tumor necrosis factor, alpha-induced protein 3)"14654-1.331-0.5452No
403456"IFNB1 (interferon, beta 1, fibroblast)"14732-1.384-0.5477No
413594"IL12RB1 (interleukin 12 receptor, beta 1)"15945-2.429-0.6053No
423055HCK (hemopoietic cell kinase)16018-2.517-0.6066No
43200316"APOBEC3F (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F)"17527-5.737-0.6757No
44114609TIRAP (toll-interleukin 1 receptor (TIR) domain containing adaptor protein)17660-6.248-0.6766No
4510053"AP1M2 (adaptor-related protein complex 1, mu 2 subunit)"17870-7.186-0.6803No
4659307SIGIRR (single immunoglobulin and toll-interleukin 1 receptor (TIR) domain)18442-10.737-0.6987Yes
475371PML (promyelocytic leukemia)18450-10.797-0.6891Yes
4851606"ATP6V1H (ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H)"18782-13.854-0.6928Yes
4951561"IL23A (interleukin 23, alpha subunit p19)"19029-17.353-0.6891Yes
5010221TRIB1 (tribbles homolog 1 (Drosophila))19194-20.406-0.6785Yes
5123586DDX58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58)19385-25.182-0.6649Yes
52375ARF1 (ADP-ribosylation factor 1)19469-27.515-0.6439Yes
5355690PACS1 (phosphofurin acidic cluster sorting protein 1)19567-30.534-0.6207Yes
545879"RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))"19612-32.214-0.5935Yes
5557506VISA (virus-induced signaling adapter)19622-32.677-0.5641Yes
565062PAK2 (p21 protein (Cdc42/Rac)-activated kinase 2)19777-40.918-0.5343Yes
57164"AP1G1 (adaptor-related protein complex 1, gamma 1 subunit)"19805-42.696-0.4966Yes
581173"AP2M1 (adaptor-related protein complex 2, mu 1 subunit)"19821-43.932-0.4572Yes
595094PCBP2 (poly(rC) binding protein 2)20076-73.183-0.4028Yes
60567B2M (beta-2-microglobulin)20305-220.982-0.2121Yes
613434IFIT1 (interferon-induced protein with tetratricopeptide repeats 1)20306-233.1720.0009Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0043900   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0043900: Random ES distribution   
Gene set null distribution of ES for GO|GO:0043900