Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | REACTOME|REACT_1095.1 |
Enrichment Score (ES) | 0.84043074 |
Normalized Enrichment Score (NES) | 1.6420327 |
Nominal p-value | 0.004716981 |
FDR q-value | 0.032982886 |
FWER p-Value | 0.811 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 4175 | MCM6 (minichromosome maintenance complex component 6) | 78 | 163.812 | 0.1625 | Yes | ||
2 | 4176 | MCM7 (minichromosome maintenance complex component 7) | 145 | 121.439 | 0.2825 | Yes | ||
3 | 4171 | MCM2 (minichromosome maintenance complex component 2) | 259 | 91.901 | 0.3702 | Yes | ||
4 | 55388 | MCM10 (minichromosome maintenance complex component 10) | 514 | 61.311 | 0.4199 | Yes | ||
5 | 5557 | "PRIM1 (primase, DNA, polypeptide 1 (49kDa))" | 756 | 47.079 | 0.4559 | Yes | ||
6 | 4172 | MCM3 (minichromosome maintenance complex component 3) | 816 | 43.892 | 0.4975 | Yes | ||
7 | 10926 | DBF4 (DBF4 homolog (S. cerevisiae)) | 850 | 42.705 | 0.5392 | Yes | ||
8 | 4174 | MCM5 (minichromosome maintenance complex component 5) | 954 | 38.341 | 0.5731 | Yes | ||
9 | 990 | CDC6 (cell division cycle 6 homolog (S. cerevisiae)) | 1098 | 33.817 | 0.6004 | Yes | ||
10 | 23594 | "ORC6L (origin recognition complex, subunit 6 like (yeast))" | 1148 | 32.456 | 0.6309 | Yes | ||
11 | 6119 | "RPA3 (replication protein A3, 14kDa)" | 1289 | 29.297 | 0.6537 | Yes | ||
12 | 23649 | "POLA2 (polymerase (DNA directed), alpha 2 (70kD subunit))" | 1598 | 23.976 | 0.6629 | Yes | ||
13 | 4998 | "ORC1L (origin recognition complex, subunit 1-like (yeast))" | 1658 | 23.133 | 0.6835 | Yes | ||
14 | 81620 | CDT1 (chromatin licensing and DNA replication factor 1) | 1790 | 21.205 | 0.6986 | Yes | ||
15 | 4999 | "ORC2L (origin recognition complex, subunit 2-like (yeast))" | 1830 | 20.770 | 0.7177 | Yes | ||
16 | 4173 | MCM4 (minichromosome maintenance complex component 4) | 1938 | 19.630 | 0.7324 | Yes | ||
17 | 5001 | "ORC5L (origin recognition complex, subunit 5-like (yeast))" | 2030 | 18.486 | 0.7467 | Yes | ||
18 | 5558 | "PRIM2 (primase, DNA, polypeptide 2 (58kDa))" | 2031 | 18.485 | 0.7654 | Yes | ||
19 | 6118 | "RPA2 (replication protein A2, 32kDa)" | 2048 | 18.355 | 0.7833 | Yes | ||
20 | 1017 | CDK2 (cyclin-dependent kinase 2) | 2122 | 17.731 | 0.7977 | Yes | ||
21 | 8318 | CDC45L (CDC45 cell division cycle 45-like (S. cerevisiae)) | 2151 | 17.475 | 0.8140 | Yes | ||
22 | 5427 | "POLE2 (polymerase (DNA directed), epsilon 2 (p59 subunit))" | 2176 | 17.332 | 0.8305 | Yes | ||
23 | 5422 | "POLA1 (polymerase (DNA directed), alpha 1, catalytic subunit)" | 2543 | 13.945 | 0.8266 | Yes | ||
24 | 6117 | "RPA1 (replication protein A1, 70kDa)" | 2549 | 13.888 | 0.8404 | Yes | ||
25 | 8317 | CDC7 (cell division cycle 7 homolog (S. cerevisiae)) | 3178 | 10.056 | 0.8197 | No | ||
26 | 23595 | "ORC3L (origin recognition complex, subunit 3-like (yeast))" | 3538 | 8.626 | 0.8108 | No | ||
27 | 5426 | "POLE (polymerase (DNA directed), epsilon)" | 5878 | 2.520 | 0.6981 | No | ||
28 | 29935 | "RPA4 (replication protein A4, 34kDa)" | 8120 | 0.684 | 0.5884 | No | ||
29 | 5000 | "ORC4L (origin recognition complex, subunit 4-like (yeast))" | 18666 | -12.706 | 0.0817 | No |