Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0044437
Enrichment Score (ES)-0.64099467
Normalized Enrichment Score (NES)-1.5835198
Nominal p-value0.0
FDR q-value0.29513928
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0044437   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
181567TXNDC5 (thioredoxin domain containing 5)65751.6060.0040No
254978C2orf18 (chromosome 2 open reading frame 18)149625.436-0.0194No
36845VAMP7 (vesicle-associated membrane protein 7)170222.357-0.0137No
4162"AP1B1 (adaptor-related protein complex 1, beta 1 subunit)"202018.565-0.0163No
5121260"SLC15A4 (solute carrier family 15, member 4)"215217.461-0.0104No
68905"AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)"224016.745-0.0029No
79296"ATP6V1F (ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F)"228816.1170.0062No
85641LGMN (legumain)229616.0790.0172No
910058"ABCB6 (ATP-binding cassette, sub-family B (MDR/TAP), member 6)"231615.8920.0275No
103123"HLA-DRB1 (major histocompatibility complex, class II, DR beta 1)"257913.6550.0242No
1151361HOOK1 (hook homolog 1 (Drosophila))275712.4420.0243No
128907"AP1M1 (adaptor-related protein complex 1, mu 1 subunit)"314510.2050.0124No
1353373TPCN1 (two pore segment channel 1)34718.8540.0026No
14284129"SLC26A11 (solute carrier family 26, member 11)"37117.893-0.0037No
15219931TPCN2 (two pore segment channel 2)37477.7160.0001No
16130340"AP1S3 (adaptor-related protein complex 1, sigma 3 subunit)"37747.6150.0042No
171203"CLN5 (ceroid-lipofuscinosis, neuronal 5)"41026.430-0.0074No
1857617VPS18 (vacuolar protein sorting 18 homolog (S. cerevisiae))43495.628-0.0156No
193126"HLA-DRB4 (major histocompatibility complex, class II, DR beta 4)"43715.560-0.0127No
2023457"ABCB9 (ATP-binding cassette, sub-family B (MDR/TAP), member 9)"45535.110-0.0180No
211174"AP1S1 (adaptor-related protein complex 1, sigma 1 subunit)"46824.756-0.0210No
22408"ARRB1 (arrestin, beta 1)"49284.173-0.0302No
2327072VPS41 (vacuolar protein sorting 41 homolog (S. cerevisiae))53233.359-0.0472No
243127"HLA-DRB5 (major histocompatibility complex, class II, DR beta 5)"60782.255-0.0829No
2584376HOOK3 (hook homolog 3 (Drosophila))64161.860-0.0982No
2663894C14orf133 (chromosome 14 open reading frame 133)73241.116-0.1422No
271538"CYLC1 (cylicin, basic protein of sperm head cytoskeleton 1)"73251.115-0.1414No
28245972"ATP6V0D2 (ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2)"75890.949-0.1538No
2949ACR (acrosin)76970.890-0.1584No
304948OCA2 (oculocutaneous albinism II)80530.708-0.1754No
3151296"SLC15A3 (solute carrier family 15, member 3)"93220.299-0.2378No
32358AQP1 (aquaporin 1 (Colton blood group))102260.078-0.2824No
3355016MARCH1 (membrane-associated ring finger (C3HC4) 1)10672-0.020-0.3043No
342638GC (group-specific component (vitamin D binding protein))11511-0.216-0.3456No
35525"ATP6V1B1 (ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1)"11564-0.227-0.3480No
364935GPR143 (G protein-coupled receptor 143)12434-0.440-0.3906No
379525VPS4B (vacuolar protein sorting 4 homolog B (S. cerevisiae))13180-0.662-0.4269No
384647MYO7A (myosin VIIA)13917-0.960-0.4626No
399725TMEM63A (transmembrane protein 63A)14038-1.014-0.4678No
408029CUBN (cubilin (intrinsic factor-cobalamin receptor))14416-1.188-0.4856No
4164601VPS16 (vacuolar protein sorting 16 homolog (S. cerevisiae))15648-2.096-0.5449No
4265082VPS33A (vacuolar protein sorting 33 homolog A (S. cerevisiae))15667-2.113-0.5443No
43138050HGSNAT (heparan-alpha-glucosaminide N-acetyltransferase)16006-2.509-0.5592No
441497"CTNS (cystinosis, nephropathic)"16959-4.140-0.6033No
4523339VPS39 (vacuolar protein sorting 39 homolog (S. cerevisiae))17133-4.592-0.6086No
4611342RNF13 (ring finger protein 13)17465-5.513-0.6210No
4710053"AP1M2 (adaptor-related protein complex 1, mu 2 subunit)"17870-7.186-0.6359Yes
4826276VPS33B (vacuolar protein sorting 33 homolog B (yeast))17902-7.377-0.6322Yes
4955062"WIPI1 (WD repeat domain, phosphoinositide interacting 1)"17994-7.878-0.6312Yes
503122"HLA-DRA (major histocompatibility complex, class II, DR alpha)"17997-7.888-0.6257Yes
515664PSEN2 (presenilin 2 (Alzheimer disease 4))18005-7.937-0.6204Yes
524891"SLC11A2 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2)"18016-7.985-0.6153Yes
5311337GABARAP (GABA(A) receptor-associated protein)18240-9.216-0.6198Yes
54373TRIM23 (tripartite motif-containing 23)18300-9.614-0.6159Yes
5526503"SLC17A5 (solute carrier family 17 (anion/sugar transporter), member 5)"18347-9.886-0.6112Yes
5683547RILP (Rab interacting lysosomal protein)18383-10.168-0.6057Yes
572647"BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1)"18593-11.970-0.6076Yes
5850617"ATP6V0A4 (ATPase, H+ transporting, lysosomal V0 subunit a4)"18596-11.995-0.5992Yes
592629"GBA (glucosidase, beta; acid (includes glucosylceramidase))"18623-12.262-0.5918Yes
6051606"ATP6V1H (ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H)"18782-13.854-0.5899Yes
611200TPP1 (tripeptidyl peptidase I)19050-17.858-0.5904Yes
6255315"SLC29A3 (solute carrier family 29 (nucleoside transporters), member 3)"19100-18.778-0.5796Yes
6329911HOOK2 (hook homolog 2 (Drosophila))19137-19.542-0.5675Yes
6455823VPS11 (vacuolar protein sorting 11 homolog (S. cerevisiae))19149-19.713-0.5542Yes
659114"ATP6V0D1 (ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1)"19347-24.177-0.5468Yes
6651092"SIDT2 (SID1 transmembrane family, member 2)"19507-28.505-0.5345Yes
675663PSEN1 (presenilin 1)19728-38.379-0.5183Yes
6810437"IFI30 (interferon, gamma-inducible protein 30)"19766-40.310-0.4916Yes
69164"AP1G1 (adaptor-related protein complex 1, gamma 1 subunit)"19805-42.696-0.4633Yes
7064400AKTIP (AKT interacting protein)19904-51.459-0.4318Yes
7126100"WIPI2 (WD repeat domain, phosphoinositide interacting 2)"19912-52.575-0.3950Yes
721201"CLN3 (ceroid-lipofuscinosis, neuronal 3)"19985-61.160-0.3554Yes
735660PSAP (prosaposin)19990-61.664-0.3120Yes
743920LAMP2 (lysosomal-associated membrane protein 2)20061-70.710-0.2655Yes
75950"SCARB2 (scavenger receptor class B, member 2)"20115-83.041-0.2094Yes
7651382"ATP6V1D (ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D)"20158-96.933-0.1430Yes
7711345GABARAPL2 (GABA(A) receptor-associated protein-like 2)20300-214.0170.0012Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0044437   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0044437: Random ES distribution   
Gene set null distribution of ES for GO|GO:0044437