Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0051222
Enrichment Score (ES)-0.6839749
Normalized Enrichment Score (NES)-1.6766028
Nominal p-value0.0035587188
FDR q-value0.17720422
FWER p-Value0.98
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0051222   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1999"CDH1 (cadherin 1, type 1, E-cadherin (epithelial))"59755.2880.0201No
294121SYTL4 (synaptotagmin-like 4)188320.129-0.0253No
3657"BMPR1A (bone morphogenetic protein receptor, type IA)"216817.378-0.0237No
44282MIF (macrophage migration inhibitory factor (glycosylation-inhibiting factor))237515.341-0.0201No
58877SPHK1 (sphingosine kinase 1)247414.588-0.0119No
623705CADM1 (cell adhesion molecule 1)256113.762-0.0038No
711030RBPMS (RNA binding protein with multiple splicing)32329.780-0.0281No
82010EMD (emerin)35498.598-0.0360No
964127NOD2 (nucleotide-binding oligomerization domain containing 2)35948.389-0.0307No
107040"TGFB1 (transforming growth factor, beta 1)"36658.104-0.0268No
1124145PANX1 (pannexin 1)43625.589-0.0562No
121956"EGFR (epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian))"52923.407-0.0990No
1343ACHE (acetylcholinesterase (Yt blood group))56452.852-0.1139No
142150F2RL1 (coagulation factor II (thrombin) receptor-like 1)59232.465-0.1253No
157293"TNFRSF4 (tumor necrosis factor receptor superfamily, member 4)"62662.038-0.1404No
166289SAA2 (serum amyloid A2)66701.616-0.1589No
177545"ZIC1 (Zic family member 1 (odd-paired homolog, Drosophila))"67351.562-0.1606No
1822900"CARD8 (caspase recruitment domain family, member 8)"67681.538-0.1608No
193479IGF1 (insulin-like growth factor 1 (somatomedin C))70981.270-0.1759No
20340061TMEM173 (transmembrane protein 173)73611.090-0.1879No
218740"TNFSF14 (tumor necrosis factor (ligand) superfamily, member 14)"77330.873-0.2054No
223357HTR2B (5-hydroxytryptamine (serotonin) receptor 2B)78720.797-0.2116No
232932GSK3B (glycogen synthase kinase 3 beta)80180.725-0.2181No
24163882C1orf71 (chromosome 1 open reading frame 71)81140.686-0.2221No
257097TLR2 (toll-like receptor 2)83860.583-0.2350No
2622861"NLRP1 (NLR family, pyrin domain containing 1)"88790.422-0.2589No
27192683SCAMP5 (secretory carrier membrane protein 5)90000.386-0.2645No
2855801IL26 (interleukin 26)93110.302-0.2796No
295950"RBP4 (retinol binding protein 4, plasma)"94480.266-0.2860No
30939CD27 (CD27 molecule)94530.264-0.2860No
3127159"CHIA (chitinase, acidic)"96610.218-0.2960No
323569"IL6 (interleukin 6 (interferon, beta 2))"97700.188-0.3012No
33101ADAM8 (ADAM metallopeptidase domain 8)97840.185-0.3017No
343586IL10 (interleukin 10)98010.182-0.3023No
35727C5 (complement component 5)99250.151-0.3082No
3610626TRIM16 (tripartite motif-containing 16)99530.146-0.3094No
377474"WNT5A (wingless-type MMTV integration site family, member 5A)"101640.093-0.3197No
385319"PLA2G1B (phospholipase A2, group IB (pancreas))"103690.046-0.3298No
3951284TLR7 (toll-like receptor 7)104920.016-0.3358No
404089SMAD4 (SMAD family member 4)10664-0.017-0.3442No
4156253CRTAM (cytotoxic and regulatory T cell molecule)11311-0.166-0.3760No
4290865IL33 (interleukin 33)11364-0.182-0.3784No
433593"IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))"11374-0.185-0.3786No
443630INS (insulin)11442-0.201-0.3818No
457292"TNFSF4 (tumor necrosis factor (ligand) superfamily, member 4)"11460-0.205-0.3824No
467042"TGFB2 (transforming growth factor, beta 2)"11675-0.254-0.3928No
477098TLR3 (toll-like receptor 3)11911-0.304-0.4041No
483553"IL1B (interleukin 1, beta)"11912-0.304-0.4038No
49260434PYDC1 (PYD (pyrin domain) containing 1)12140-0.355-0.4147No
505027"P2RX7 (purinergic receptor P2X, ligand-gated ion channel, 7)"12248-0.386-0.4197No
511950EGF (epidermal growth factor (beta-urogastrone))12439-0.441-0.4287No
5255655"NLRP2 (NLR family, pyrin domain containing 2)"12539-0.465-0.4331No
532149F2R (coagulation factor II (thrombin) receptor)12636-0.496-0.4374No
547124"TNF (tumor necrosis factor (TNF superfamily, member 2))"12777-0.537-0.4439No
556363CCL19 (chemokine (C-C motif) ligand 19)12834-0.556-0.4461No
565460POU5F1 (POU class 5 homeobox 1)13341-0.718-0.4705No
573552"IL1A (interleukin 1, alpha)"13376-0.731-0.4715No
58114548"NLRP3 (NLR family, pyrin domain containing 3)"13741-0.872-0.4887No
597099TLR4 (toll-like receptor 4)14032-1.010-0.5021No
6023086EXPH5 (exophilin 5)15077-1.621-0.5522No
6190070LACRT (lacritin)15089-1.628-0.5513No
6254106TLR9 (toll-like receptor 9)15160-1.682-0.5533No
6391662"NLRP12 (NLR family, pyrin domain containing 12)"15825-2.282-0.5840No
6411146"GLMN (glomulin, FKBP associated protein)"17334-5.100-0.6539No
65283"ANG (angiogenin, ribonuclease, RNase A family, 5)"17573-5.893-0.6604No
667046"TGFBR1 (transforming growth factor, beta receptor 1)"18051-8.147-0.6767Yes
677043"TGFB3 (transforming growth factor, beta 3)"18102-8.466-0.6715Yes
687205TRIP6 (thyroid hormone receptor interactor 6)18141-8.698-0.6656Yes
6929108PYCARD (PYD and CARD domain containing)18363-9.973-0.6676Yes
70652BMP4 (bone morphogenetic protein 4)18378-10.143-0.6592Yes
718754ADAM9 (ADAM metallopeptidase domain 9 (meltrin gamma))18549-11.504-0.6572Yes
724088SMAD3 (SMAD family member 3)18573-11.772-0.6478Yes
7351561"IL23A (interleukin 23, alpha subunit p19)"19029-17.353-0.6547Yes
742316"FLNA (filamin A, alpha (actin binding protein 280))"19138-19.560-0.6425Yes
7523586DDX58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58)19385-25.182-0.6321Yes
7651366UBR5 (ubiquitin protein ligase E3 component n-recognin 5)19390-25.318-0.6096Yes
77387"RHOA (ras homolog gene family, member A)"19574-30.675-0.5911Yes
7857506VISA (virus-induced signaling adapter)19622-32.677-0.5641Yes
796934"TCF7L2 (transcription factor 7-like 2 (T-cell specific, HMG-box))"19726-38.340-0.5348Yes
803728JUP (junction plakoglobin)19987-61.273-0.4926Yes
812625GATA3 (GATA binding protein 3)20312-255.499-0.2794Yes
8225805BAMBI (BMP and activin membrane-bound inhibitor homolog (Xenopus laevis))20317-312.0360.0004Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0051222   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0051222: Random ES distribution   
Gene set null distribution of ES for GO|GO:0051222