Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetKEGG|HSA05412
Enrichment Score (ES)-0.6668577
Normalized Enrichment Score (NES)-1.6168008
Nominal p-value0.009868421
FDR q-value0.2541918
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: KEGG|HSA05412   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
11499"CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa)"48063.9320.0314No
281"ACTN4 (actinin, alpha 4)"113632.7500.0272No
33673"ITGA2 (integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor))"127129.6710.0461No
46443"SGCB (sarcoglycan, beta (43kDa dystrophin-associated glycoprotein))"195319.4000.0292No
51829DSG2 (desmoglein 2)198019.0240.0443No
6488"ATP2A2 (ATPase, Ca++ transporting, cardiac muscle, slow twitch 2)"278512.2950.0152No
787"ACTN1 (actinin, alpha 1)"295011.3240.0169No
82010EMD (emerin)35498.598-0.0053No
93675"ITGA3 (integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor))"43985.483-0.0424No
10786"CACNG1 (calcium channel, voltage-dependent, gamma subunit 1)"52943.402-0.0837No
113688"ITGB1 (integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12))"54403.175-0.0881No
121000"CDH2 (cadherin 2, type 1, N-cadherin (neuronal))"56422.854-0.0956No
133908"LAMA2 (laminin, alpha 2)"57122.730-0.0966No
146546"SLC8A1 (solute carrier family 8 (sodium/calcium exchanger), member 1)"62632.049-0.1220No
1510369"CACNG2 (calcium channel, voltage-dependent, gamma subunit 2)"63941.890-0.1268No
1610368"CACNG3 (calcium channel, voltage-dependent, gamma subunit 3)"65651.711-0.1337No
173679"ITGA7 (integrin, alpha 7)"67241.575-0.1402No
181674DES (desmin)67271.572-0.1389No
193695"ITGB7 (integrin, beta 7)"72001.196-0.1612No
206262RYR2 (ryanodine receptor 2 (cardiac))72331.172-0.1618No
21775"CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit)"72391.168-0.1610No
226444"SGCD (sarcoglycan, delta (35kDa dystrophin-associated glycoprotein))"72891.143-0.1625No
2329119"CTNNA3 (catenin (cadherin-associated protein), alpha 3)"73101.127-0.1625No
249254"CACNA2D2 (calcium channel, voltage-dependent, alpha 2/delta subunit 2)"76710.900-0.1795No
25124989C17orf57 (chromosome 17 open reading frame 57)78810.793-0.1891No
26783"CACNB2 (calcium channel, voltage-dependent, beta 2 subunit)"81410.678-0.2013No
273680"ITGA9 (integrin, alpha 9)"95360.246-0.2699No
283672"ITGA1 (integrin, alpha 1)"103100.061-0.3081No
29778"CACNA1F (calcium channel, voltage-dependent, L type, alpha 1F subunit)"104700.020-0.3159No
303696"ITGB8 (integrin, beta 8)"10596-0.003-0.3221No
313674"ITGA2B (integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41))"10821-0.051-0.3331No
3255799"CACNA2D3 (calcium channel, voltage-dependent, alpha 2/delta subunit 3)"10930-0.078-0.3384No
3393589"CACNA2D4 (calcium channel, voltage-dependent, alpha 2/delta subunit 4)"11422-0.196-0.3624No
343676"ITGA4 (integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor))"11477-0.208-0.3649No
351496"CTNNA2 (catenin (cadherin-associated protein), alpha 2)"11513-0.216-0.3665No
3659283"CACNG8 (calcium channel, voltage-dependent, gamma subunit 8)"11764-0.273-0.3786No
3722801"ITGA11 (integrin, alpha 11)"11965-0.314-0.3882No
3827091"CACNG5 (calcium channel, voltage-dependent, gamma subunit 5)"12129-0.354-0.3959No
3989"ACTN3 (actinin, alpha 3)"12429-0.439-0.4103No
4051176LEF1 (lymphoid enhancer-binding factor 1)12631-0.495-0.4198No
412697"GJA1 (gap junction protein, alpha 1, 43kDa)"13031-0.617-0.4390No
4259284"CACNG7 (calcium channel, voltage-dependent, gamma subunit 7)"13119-0.643-0.4427No
438515"ITGA10 (integrin, alpha 10)"13455-0.762-0.4586No
44781"CACNA2D1 (calcium channel, voltage-dependent, alpha 2/delta subunit 1)"14094-1.044-0.4892No
456442"SGCA (sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein))"14500-1.239-0.5081No
46782"CACNB1 (calcium channel, voltage-dependent, beta 1 subunit)"14788-1.415-0.5211No
4788"ACTN2 (actinin, alpha 2)"14817-1.429-0.5212No
48779"CACNA1S (calcium channel, voltage-dependent, L type, alpha 1S subunit)"14936-1.512-0.5258No
498516"ITGA8 (integrin, alpha 8)"15186-1.713-0.5366No
5083439"TCF7L1 (transcription factor 7-like 1 (T-cell specific, HMG-box))"15271-1.773-0.5392No
51784"CACNB3 (calcium channel, voltage-dependent, beta 3 subunit)"15437-1.904-0.5457No
521756DMD (dystrophin)15542-2.006-0.5491No
533690"ITGB3 (integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61))"15709-2.159-0.5555No
54785"CACNB4 (calcium channel, voltage-dependent, beta 4 subunit)"15727-2.181-0.5544No
55776"CACNA1D (calcium channel, voltage-dependent, L type, alpha 1D subunit)"16107-2.645-0.5709No
563655"ITGA6 (integrin, alpha 6)"16228-2.794-0.5744No
575318PKP2 (plakophilin 2)16721-3.639-0.5955No
583678"ITGA5 (integrin, alpha 5 (fibronectin receptor, alpha polypeptide))"16955-4.130-0.6035No
596932"TCF7 (transcription factor 7 (T-cell specific, HMG-box))"17249-4.855-0.6138No
604000LMNA (lamin A/C)17307-5.012-0.6123No
6127092"CACNG4 (calcium channel, voltage-dependent, gamma subunit 4)"17895-7.344-0.6349No
623691"ITGB4 (integrin, beta 4)"18322-9.752-0.6476No
6359285"CACNG6 (calcium channel, voltage-dependent, gamma subunit 6)"18669-12.766-0.6537Yes
641824DSC2 (desmocollin 2)18677-12.814-0.6430Yes
653694"ITGB6 (integrin, beta 6)"18774-13.800-0.6358Yes
663685"ITGAV (integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51))"19403-25.664-0.6448Yes
673693"ITGB5 (integrin, beta 5)"19543-29.664-0.6261Yes
686934"TCF7L2 (transcription factor 7-like 2 (T-cell specific, HMG-box))"19726-38.340-0.6021Yes
691605DAG1 (dystroglycan 1 (dystrophin-associated glycoprotein 1))19828-44.564-0.5687Yes
703728JUP (junction plakoglobin)19987-61.273-0.5237Yes
716445"SGCG (sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein))"20063-70.736-0.4665Yes
721832DSP (desmoplakin)20110-82.287-0.3979Yes
731495"CTNNA1 (catenin (cadherin-associated protein), alpha 1, 102kDa)"20167-99.680-0.3148Yes
7471"ACTG1 (actin, gamma 1)"20270-173.229-0.1707Yes
7560"ACTB (actin, beta)"20292-201.3250.0016Yes
Table: GSEA details [plain text format]



Fig 2: KEGG|HSA05412   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KEGG|HSA05412: Random ES distribution   
Gene set null distribution of ES for KEGG|HSA05412