Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0030133
Enrichment Score (ES)-0.7995264
Normalized Enrichment Score (NES)-1.9036759
Nominal p-value0.0
FDR q-value0.002433711
FWER p-Value0.0060
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0030133   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1203547LOC203547 (hypothetical protein LOC203547)112633.003-0.0375No
290411MCFD2 (multiple coagulation factor deficiency 2)116931.966-0.0220No
3858CAV2 (caveolin 2)297111.142-0.1048No
480023NRSN2 (neurensin 2)318310.037-0.1097No
511161C14orf1 (chromosome 14 open reading frame 1)32989.540-0.1101No
68269TMEM187 (transmembrane protein 187)36038.333-0.1205No
755435C4orf16 (chromosome 4 open reading frame 16)36048.332-0.1159No
86857SYT1 (synaptotagmin I)39267.010-0.1279No
91174"AP1S1 (adaptor-related protein complex 1, sigma 1 subunit)"46824.756-0.1626No
10160"AP2A1 (adaptor-related protein complex 2, alpha 1 subunit)"46984.725-0.1607No
1151324"SPG21 (spastic paraplegia 21 (autosomal recessive, Mast syndrome))"49184.193-0.1692No
1210427"SEC24B (SEC24 related gene family, member B (S. cerevisiae))"52223.561-0.1822No
135864"RAB3A (RAB3A, member RAS oncogene family)"52863.419-0.1835No
14762CA4 (carbonic anhydrase IV)57942.623-0.2071No
151176"AP3S1 (adaptor-related protein complex 3, sigma 1 subunit)"58222.587-0.2070No
16359AQP2 (aquaporin 2 (collecting duct))64961.785-0.2392No
1781562"LMAN2L (lectin, mannose-binding 2-like)"68791.430-0.2573No
1823392KIAA0368 (KIAA0368)69221.396-0.2586No
1978992"YIPF2 (Yip1 domain family, member 2)"73901.071-0.2811No
20163882C1orf71 (chromosome 1 open reading frame 71)81140.686-0.3164No
21117248GALNTL2 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2)86300.503-0.3415No
228906"AP1G2 (adaptor-related protein complex 1, gamma 2 subunit)"88580.428-0.3525No
2357120GOPC (golgi associated PDZ and coiled-coil motif containing)88850.421-0.3535No
246572"SLC18A3 (solute carrier family 18 (vesicular acetylcholine), member 3)"90240.377-0.3601No
25140767NRSN1 (neurensin 1)95510.241-0.3860No
266570"SLC18A1 (solute carrier family 18 (vesicular monoamine), member 1)"95630.238-0.3864No
2783988NCALD (neurocalcin delta)97410.197-0.3950No
28261729STEAP2 (six transmembrane epithelial antigen of the prostate 2)12567-0.474-0.5342No
2957586SYT13 (synaptotagmin XIII)12788-0.541-0.5448No
309182RASSF9 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 9)13400-0.741-0.5746No
315873"RAB27A (RAB27A, member RAS oncogene family)"13611-0.820-0.5845No
328082SSPN (sarcospan (Kras oncogene-associated gene))13751-0.877-0.5908No
336571"SLC18A2 (solute carrier family 18 (vesicular monoamine), member 2)"13806-0.903-0.5930No
3411276AP1GBP1 (AP1 gamma subunit binding protein 1)14922-1.502-0.6472No
35633BGN (biglycan)15128-1.662-0.6564No
36201294UNC13D (unc-13 homolog D (C. elegans))15171-1.699-0.6576No
3764418TMEM168 (transmembrane protein 168)15273-1.775-0.6616No
389871"SEC24D (SEC24 related gene family, member D (S. cerevisiae))"15378-1.853-0.6657No
39363"AQP6 (aquaporin 6, kidney specific)"15778-2.238-0.6842No
4057030"SLC17A7 (solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7)"16056-2.581-0.6964No
4151128SAR1B (SAR1 gene homolog B (S. cerevisiae))16892-3.976-0.7355No
4226119LDLRAP1 (low density lipoprotein receptor adaptor protein 1)16987-4.212-0.7378No
436844VAMP2 (vesicle-associated membrane protein 2 (synaptobrevin 2))17160-4.647-0.7437No
445045FURIN (furin (paired basic amino acid cleaving enzyme))17734-6.604-0.7684No
4583716CRISPLD2 (cysteine-rich secretory protein LCCL domain containing 2)17766-6.775-0.7662No
469632"SEC24C (SEC24 related gene family, member C (S. cerevisiae))"18266-9.369-0.7857No
47538"ATP7A (ATPase, Cu++ transporting, alpha polypeptide)"18547-11.483-0.7932Yes
4810802"SEC24A (SEC24 related gene family, member A (S. cerevisiae))"18548-11.495-0.7869Yes
493482IGF2R (insulin-like growth factor 2 receptor)18791-13.902-0.7912Yes
506396SEC13 (SEC13 homolog (S. cerevisiae))18834-14.381-0.7854Yes
5154432"YIPF1 (Yip1 domain family, member 1)"18928-15.605-0.7814Yes
5283464APH1B (anterior pharynx defective 1 homolog B (C. elegans))18937-15.812-0.7731Yes
5325844"YIPF3 (Yip1 domain family, member 3)"19174-20.092-0.7737Yes
5410484SEC23A (Sec23 homolog A (S. cerevisiae))19218-20.816-0.7644Yes
553134"HLA-F (major histocompatibility complex, class I, F)"19233-21.099-0.7535Yes
569114"ATP6V0D1 (ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1)"19347-24.177-0.7458Yes
573133"HLA-E (major histocompatibility complex, class I, E)"19478-27.797-0.7370Yes
5851552"RAB14 (RAB14, member RAS oncogene family)"19535-29.482-0.7236Yes
5922872SEC31A (SEC31 homolog A (S. cerevisiae))19760-39.650-0.7128Yes
6010618TGOLN2 (trans-golgi network protein 2)19850-46.283-0.6918Yes
613135"HLA-G (major histocompatibility complex, class I, G)"19863-47.478-0.6663Yes
623998"LMAN1 (lectin, mannose-binding, 1)"19954-57.564-0.6391Yes
6354812AFTPH (aftiphilin)19968-58.680-0.6076Yes
643105"HLA-A (major histocompatibility complex, class I, A)"20027-65.132-0.5746Yes
653106"HLA-B (major histocompatibility complex, class I, B)"20100-78.491-0.5351Yes
6654843SYTL2 (synaptotagmin-like 2)20210-119.018-0.4751Yes
673107"HLA-C (major histocompatibility complex, class I, C)"20243-142.867-0.3982Yes
685874"RAB27B (RAB27B, member RAS oncogene family)"20248-150.223-0.3159Yes
69567B2M (beta-2-microglobulin)20305-220.982-0.1973Yes
7079666"PLEKHF2 (pleckstrin homology domain containing, family F (with FYVE domain) member 2)"20321-360.8950.0002Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0030133   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0030133: Random ES distribution   
Gene set null distribution of ES for GO|GO:0030133