Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classtreated
GeneSetREACTOME|REACT_6256.3
Enrichment Score (ES)0.7160201
Normalized Enrichment Score (NES)1.6139944
Nominal p-value0.0
FDR q-value0.04644718
FWER p-Value0.967
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME|REACT_6256.3   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
15901"RAN (RAN, member RAS oncogene family)"27250.1270.0871Yes
25902RANBP1 (RAN binding protein 1)172109.9520.1189Yes
35431"POLR2B (polymerase (RNA) II (DNA directed) polypeptide B, 140kDa)"24893.7050.1484Yes
457122NUP107 (nucleoporin 107kDa)27689.5880.1787Yes
57520XRCC5 (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))30085.7970.2079Yes
62547XRCC6 (X-ray repair complementing defective repair in Chinese hamster cells 6)30784.4120.2375Yes
78480RAE1 (RAE1 RNA export 1 homolog (S. pombe))32283.3120.2663Yes
82966"GTF2H2 (general transcription factor IIH, polypeptide 2, 44kDa)"33780.9800.2942Yes
92237FEN1 (flap structure-specific endonuclease 1)34879.3160.3218Yes
106921"TCEB1 (transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C))"37775.3770.3471Yes
118815BANF1 (barrier to autointegration factor 1)40571.7380.3711Yes
125436POLR2G (polymerase (RNA) II (DNA directed) polypeptide G)43967.7680.3934Yes
1311198SUPT16H (suppressor of Ty 16 homolog (S. cerevisiae))48463.4690.4137Yes
14129401NUP35 (nucleoporin 35kDa)50261.8730.4348Yes
155435POLR2F (polymerase (RNA) II (DNA directed) polypeptide F)53160.3460.4547Yes
16902CCNH (cyclin H)53659.5430.4756Yes
177514"XPO1 (exportin 1 (CRM1 homolog, yeast))"53959.4620.4965Yes
185441"POLR2L (polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa)"65551.8330.5092Yes
196923"TCEB2 (transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B))"70748.6990.5239Yes
2079023NUP37 (nucleoporin 37kDa)77046.1890.5371Yes
216882"TAF11 (TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa)"85442.4290.5480Yes
224686"NCBP1 (nuclear cap binding protein subunit 1, 80kDa)"86042.2660.5627Yes
239972NUP153 (nucleoporin 153kDa)92439.6720.5737Yes
2423636NUP62 (nucleoporin 62kDa)98037.6920.5843Yes
2522916"NCBP2 (nuclear cap binding protein subunit 2, 20kDa)"98637.5280.5973Yes
2610762NUP50 (nucleoporin 50kDa)113232.8600.6018Yes
2723165NUP205 (nucleoporin 205kDa)114332.6050.6128Yes
284927NUP88 (nucleoporin 88kDa)114932.4550.6240Yes
295438"POLR2I (polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa)"115732.2490.6351Yes
306878"TAF6 (TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa)"122330.5550.6427Yes
312967"GTF2H3 (general transcription factor IIH, polypeptide 3, 34kDa)"127329.6250.6507Yes
325434"POLR2E (polymerase (RNA) II (DNA directed) polypeptide E, 25kDa)"132828.2680.6581Yes
336880"TAF9 (TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa)"150125.3500.6585Yes
3453371NUP54 (nucleoporin 54kDa)160423.8590.6619Yes
356917"TCEA1 (transcription elongation factor A (SII), 1)"163523.4060.6687Yes
369631NUP155 (nucleoporin 155kDa)164123.3600.6768Yes
372957"GTF2A1 (general transcription factor IIA, 1, 19/37kDa)"167922.7080.6830Yes
385433POLR2D (polymerase (RNA) II (DNA directed) polypeptide D)174721.7110.6873Yes
396874"TAF4 (TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa)"175921.5090.6944Yes
405432"POLR2C (polymerase (RNA) II (DNA directed) polypeptide C, 33kDa)"177221.3890.7014Yes
4123279NUP160 (nucleoporin 160kDa)180420.9880.7073Yes
426749SSRP1 (structure specific recognition protein 1)194319.5770.7074Yes
432963"GTF2F2 (general transcription factor IIF, polypeptide 2, 30kDa)"205618.2640.7083Yes
445903RANBP2 (RAN binding protein 2)216417.3990.7091Yes
45905CCNT2 (cyclin T2)242914.8800.7014Yes
4623511NUP188 (nucleoporin 188kDa)262313.2560.6965Yes
476881"TAF10 (TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa)"268112.9630.6983Yes
481104RCC1 (regulator of chromosome condensation 1)270012.8700.7019Yes
499688NUP93 (nucleoporin 93kDa)270912.8140.7061Yes
502961"GTF2E2 (general transcription factor IIE, polypeptide 2, beta 34kDa)"273012.6400.7096Yes
5155746NUP133 (nucleoporin 133kDa)278712.2810.7111Yes
526877"TAF5 (TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa)"292111.5050.7086Yes
535905RANGAP1 (Ran GTPase activating protein 1)299711.0600.7088Yes
546827SUPT4H1 (suppressor of Ty 4 homolog 1 (S. cerevisiae))305810.6690.7096Yes
557936RDBP (RD RNA binding protein)308610.5150.7120Yes
566875"TAF4B (TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa)"32169.8710.7091Yes
5779902NUP85 (nucleoporin 85kDa)32899.5860.7090Yes
589150"CTDP1 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1)"33039.5180.7117Yes
59348995NUP43 (nucleoporin 43kDa)33559.3500.7125Yes
6023225NUP210 (nucleoporin 210kDa)33969.1690.7137Yes
612968"GTF2H4 (general transcription factor IIH, polypeptide 4, 52kDa)"34169.1030.7160Yes
626872"TAF1 (TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa)"35108.7050.7145No
634331"MNAT1 (menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis))"35838.4170.7139No
645430"POLR2A (polymerase (RNA) II (DNA directed) polypeptide A, 220kDa)"36268.2310.7148No
657518XRCC4 (X-ray repair complementing defective repair in Chinese hamster cells 4)39426.9750.7016No
66904CCNT1 (cyclin T1)40466.6530.6989No
675437POLR2H (polymerase (RNA) II (DNA directed) polypeptide H)45965.0000.6735No
686908TBP (TATA box binding protein)46904.7390.6706No
699883POM121 (POM121 membrane glycoprotein (rat))50273.9780.6554No
703981"LIG4 (ligase IV, DNA, ATP-dependent)"50533.9150.6556No
712068"ERCC2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)"51593.7020.6517No
722071"ERCC3 (excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing))"59442.4390.6138No
732965"GTF2H1 (general transcription factor IIH, polypeptide 1, 62kDa)"61552.1630.6042No
747469WHSC2 (Wolf-Hirschhorn syndrome candidate 2)62782.0210.5989No
755440"POLR2K (polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa)"63211.9700.5975No
762962"GTF2F1 (general transcription factor IIF, polypeptide 1, 74kDa)"63881.8940.5949No
771234CCR5 (chemokine (C-C motif) receptor 5)87600.4570.4778No
786924"TCEB3 (transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A))"103190.0590.4008No
791025CDK9 (cyclin-dependent kinase 9)104180.0340.3960No
803978"LIG1 (ligase I, DNA, ATP-dependent)"10691-0.0240.3826No
81920CD4 (CD4 molecule)12457-0.4460.2955No
826884"TAF13 (TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa)"13077-0.6300.2651No
838178ELL (elongation factor RNA polymerase II)14520-1.2540.1942No
842958"GTF2A2 (general transcription factor IIA, 2, 12kDa)"14627-1.3110.1895No
852960"GTF2E1 (general transcription factor IIE, polypeptide 1, alpha 56kDa)"16002-2.5030.1224No
868021NUP214 (nucleoporin 214kDa)16014-2.5130.1228No
878732RNGTT (RNA guanylyltransferase and 5'-phosphatase)16653-3.4990.0925No
888731RNMT (RNA (guanine-7-) methyltransferase)16887-3.9670.0823No
898086"AAAS (achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A))"16985-4.2110.0790No
906883"TAF12 (TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa)"17252-4.8580.0676No
917175TPR (translocated promoter region (to activated MET oncogene))17416-5.3360.0614No
925439"POLR2J (polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa)"18134-8.6610.0291No
9311097NUPL2 (nucleoporin like 2)18164-8.8500.0308No
942959GTF2B (general transcription factor IIB)18273-9.4290.0288No
9525920COBRA1 (cofactor of BRCA1)19016-17.134-0.0019No
9651497TH1L (TH1-like (Drosophila))19618-32.568-0.0201No
971022CDK7 (cyclin-dependent kinase 7)19757-39.600-0.0129No
985478PPIA (peptidylprolyl isomerase A (cyclophilin A))20198-115.6470.0063No
Table: GSEA details [plain text format]



Fig 2: REACTOME|REACT_6256.3   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME|REACT_6256.3: Random ES distribution   
Gene set null distribution of ES for REACTOME|REACT_6256.3