Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | GO|GO:0031253 |
Enrichment Score (ES) | 0.7407128 |
Normalized Enrichment Score (NES) | 1.6025463 |
Nominal p-value | 0.0 |
FDR q-value | 0.05487035 |
FWER p-Value | 0.991 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 9368 | "SLC9A3R1 (solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1)" | 8 | 370.748 | 0.3206 | Yes | ||
2 | 6188 | RPS3 (ribosomal protein S3) | 70 | 169.892 | 0.4646 | Yes | ||
3 | 382 | ARF6 (ADP-ribosylation factor 6) | 429 | 68.934 | 0.5067 | Yes | ||
4 | 1499 | "CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa)" | 480 | 63.932 | 0.5595 | Yes | ||
5 | 2683 | "B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1)" | 791 | 45.228 | 0.5834 | Yes | ||
6 | 25800 | "SLC39A6 (solute carrier family 39 (zinc transporter), member 6)" | 976 | 37.777 | 0.6070 | Yes | ||
7 | 6584 | "SLC22A5 (solute carrier family 22 (organic cation/carnitine transporter), member 5)" | 1113 | 33.332 | 0.6292 | Yes | ||
8 | 10672 | "GNA13 (guanine nucleotide binding protein (G protein), alpha 13)" | 1221 | 30.642 | 0.6504 | Yes | ||
9 | 5420 | PODXL (podocalyxin-like) | 1403 | 26.966 | 0.6648 | Yes | ||
10 | 57026 | "PDXP (pyridoxal (pyridoxine, vitamin B6) phosphatase)" | 1539 | 24.771 | 0.6796 | Yes | ||
11 | 23224 | "SYNE2 (spectrin repeat containing, nuclear envelope 2)" | 1868 | 20.287 | 0.6810 | Yes | ||
12 | 5756 | "TWF1 (twinfilin, actin-binding protein, homolog 1 (Drosophila))" | 2008 | 18.700 | 0.6903 | Yes | ||
13 | 5174 | PDZK1 (PDZ domain containing 1) | 2135 | 17.615 | 0.6994 | Yes | ||
14 | 23499 | MACF1 (microtubule-actin crosslinking factor 1) | 2216 | 16.993 | 0.7101 | Yes | ||
15 | 23286 | WWC1 (WW and C2 domain containing 1) | 2245 | 16.680 | 0.7232 | Yes | ||
16 | 23122 | CLASP2 (cytoplasmic linker associated protein 2) | 2397 | 15.170 | 0.7289 | Yes | ||
17 | 7168 | TPM1 (tropomyosin 1 (alpha)) | 2515 | 14.150 | 0.7353 | Yes | ||
18 | 59338 | "PLEKHA1 (pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1)" | 2638 | 13.169 | 0.7407 | Yes | ||
19 | 2768 | GNA12 (guanine nucleotide binding protein (G protein) alpha 12) | 2884 | 11.757 | 0.7388 | No | ||
20 | 8324 | FZD7 (frizzled homolog 7 (Drosophila)) | 3360 | 9.324 | 0.7234 | No | ||
21 | 8321 | FZD1 (frizzled homolog 1 (Drosophila)) | 3915 | 7.040 | 0.7022 | No | ||
22 | 5824 | PEX19 (peroxisomal biogenesis factor 19) | 4296 | 5.822 | 0.6885 | No | ||
23 | 5064 | PALM (paralemmin) | 4314 | 5.740 | 0.6926 | No | ||
24 | 11021 | "RAB35 (RAB35, member RAS oncogene family)" | 4327 | 5.693 | 0.6969 | No | ||
25 | 6868 | ADAM17 (ADAM metallopeptidase domain 17) | 4493 | 5.266 | 0.6934 | No | ||
26 | 221178 | SPATA13 (spermatogenesis associated 13) | 5070 | 3.887 | 0.6683 | No | ||
27 | 26047 | CNTNAP2 (contactin associated protein-like 2) | 5303 | 3.378 | 0.6598 | No | ||
28 | 7976 | FZD3 (frizzled homolog 3 (Drosophila)) | 5426 | 3.192 | 0.6565 | No | ||
29 | 3688 | "ITGB1 (integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12))" | 5440 | 3.175 | 0.6586 | No | ||
30 | 762 | CA4 (carbonic anhydrase IV) | 5794 | 2.623 | 0.6435 | No | ||
31 | 1803 | DPP4 (dipeptidyl-peptidase 4) | 7351 | 1.095 | 0.5676 | No | ||
32 | 54212 | "SNTG1 (syntrophin, gamma 1)" | 9173 | 0.341 | 0.4781 | No | ||
33 | 358 | AQP1 (aquaporin 1 (Colton blood group)) | 10226 | 0.078 | 0.4262 | No | ||
34 | 55600 | ITLN1 (intelectin 1 (galactofuranose binding)) | 10269 | 0.069 | 0.4242 | No | ||
35 | 2487 | FRZB (frizzled-related protein) | 10360 | 0.047 | 0.4198 | No | ||
36 | 6092 | "ROBO2 (roundabout, axon guidance receptor, homolog 2 (Drosophila))" | 10465 | 0.021 | 0.4147 | No | ||
37 | 10786 | "SLC17A3 (solute carrier family 17 (sodium phosphate), member 3)" | 10467 | 0.021 | 0.4147 | No | ||
38 | 8326 | FZD9 (frizzled homolog 9 (Drosophila)) | 10757 | -0.037 | 0.4005 | No | ||
39 | 116085 | "SLC22A12 (solute carrier family 22 (organic anion/urate transporter), member 12)" | 11108 | -0.123 | 0.3833 | No | ||
40 | 10568 | "SLC34A2 (solute carrier family 34 (sodium phosphate), member 2)" | 11558 | -0.226 | 0.3613 | No | ||
41 | 2596 | GAP43 (growth associated protein 43) | 11737 | -0.267 | 0.3528 | No | ||
42 | 6792 | CDKL5 (cyclin-dependent kinase-like 5) | 12354 | -0.415 | 0.3227 | No | ||
43 | 6424 | SFRP4 (secreted frizzled-related protein 4) | 12681 | -0.506 | 0.3071 | No | ||
44 | 10297 | APC2 (adenomatosis polyposis coli 2) | 13200 | -0.667 | 0.2821 | No | ||
45 | 84687 | "PPP1R9B (protein phosphatase 1, regulatory (inhibitor) subunit 9B)" | 13293 | -0.699 | 0.2782 | No | ||
46 | 585 | BBS4 (Bardet-Biedl syndrome 4) | 13612 | -0.822 | 0.2632 | No | ||
47 | 8029 | CUBN (cubilin (intrinsic factor-cobalamin receptor)) | 14416 | -1.188 | 0.2246 | No | ||
48 | 91147 | TMEM67 (transmembrane protein 67) | 15254 | -1.757 | 0.1848 | No | ||
49 | 324 | APC (adenomatous polyposis coli) | 15267 | -1.767 | 0.1857 | No | ||
50 | 6569 | "SLC34A1 (solute carrier family 34 (sodium phosphate), member 1)" | 15307 | -1.797 | 0.1854 | No | ||
51 | 27035 | NOX1 (NADPH oxidase 1) | 15828 | -2.286 | 0.1617 | No | ||
52 | 9181 | ARHGEF2 (rho/rac guanine nucleotide exchange factor (GEF) 2) | 16227 | -2.794 | 0.1445 | No | ||
53 | 5341 | PLEK (pleckstrin) | 16728 | -3.650 | 0.1230 | No | ||
54 | 3678 | "ITGA5 (integrin, alpha 5 (fibronectin receptor, alpha polypeptide))" | 16955 | -4.130 | 0.1154 | No | ||
55 | 59341 | "TRPV4 (transient receptor potential cation channel, subfamily V, member 4)" | 17040 | -4.371 | 0.1150 | No | ||
56 | 199 | AIF1 (allograft inflammatory factor 1) | 17050 | -4.396 | 0.1184 | No | ||
57 | 114609 | TIRAP (toll-interleukin 1 receptor (TIR) domain containing adaptor protein) | 17660 | -6.248 | 0.0937 | No | ||
58 | 2535 | FZD2 (frizzled homolog 2 (Drosophila)) | 17958 | -7.681 | 0.0857 | No | ||
59 | 84168 | ANTXR1 (anthrax toxin receptor 1) | 18056 | -8.179 | 0.0880 | No | ||
60 | 50617 | "ATP6V0A4 (ATPase, H+ transporting, lysosomal V0 subunit a4)" | 18596 | -11.995 | 0.0718 | No | ||
61 | 8323 | FZD6 (frizzled homolog 6 (Drosophila)) | 18921 | -15.537 | 0.0693 | No |