Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | REACTOME|REACT_78.2 |
Enrichment Score (ES) | 0.8055631 |
Normalized Enrichment Score (NES) | 1.6182233 |
Nominal p-value | 0.0015360983 |
FDR q-value | 0.04384947 |
FWER p-Value | 0.955 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 6432 | "SFRS7 (splicing factor, arginine/serine-rich 7, 35kDa)" | 38 | 213.976 | 0.1091 | Yes | ||
2 | 6635 | SNRPE (small nuclear ribonucleoprotein polypeptide E) | 43 | 207.433 | 0.2165 | Yes | ||
3 | 6636 | SNRPF (small nuclear ribonucleoprotein polypeptide F) | 93 | 154.388 | 0.2942 | Yes | ||
4 | 6426 | "SFRS1 (splicing factor, arginine/serine-rich 1)" | 119 | 133.017 | 0.3620 | Yes | ||
5 | 10189 | THOC4 (THO complex 4) | 158 | 117.078 | 0.4209 | Yes | ||
6 | 6634 | SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide 18kDa) | 196 | 103.434 | 0.4727 | Yes | ||
7 | 9939 | RBM8A (RNA binding motif protein 8A) | 201 | 102.613 | 0.5257 | Yes | ||
8 | 6427 | "SFRS2 (splicing factor, arginine/serine-rich 2)" | 273 | 90.107 | 0.5690 | Yes | ||
9 | 6428 | "SFRS3 (splicing factor, arginine/serine-rich 3)" | 302 | 85.664 | 0.6120 | Yes | ||
10 | 7307 | U2AF1 (U2 small nuclear RNA auxiliary factor 1) | 509 | 61.555 | 0.6338 | Yes | ||
11 | 6628 | SNRPB (small nuclear ribonucleoprotein polypeptides B and B1) | 697 | 49.717 | 0.6504 | Yes | ||
12 | 1479 | "CSTF3 (cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa)" | 767 | 46.272 | 0.6710 | Yes | ||
13 | 4686 | "NCBP1 (nuclear cap binding protein subunit 1, 80kDa)" | 860 | 42.266 | 0.6884 | Yes | ||
14 | 7884 | SLBP (stem-loop binding protein) | 966 | 37.985 | 0.7029 | Yes | ||
15 | 22916 | "NCBP2 (nuclear cap binding protein subunit 2, 20kDa)" | 986 | 37.528 | 0.7215 | Yes | ||
16 | 4116 | "MAGOH (mago-nashi homolog, proliferation-associated (Drosophila))" | 1009 | 36.619 | 0.7394 | Yes | ||
17 | 9295 | "SFRS11 (splicing factor, arginine/serine-rich 11)" | 1042 | 35.388 | 0.7561 | Yes | ||
18 | 84967 | "LSM10 (LSM10, U7 small nuclear RNA associated)" | 1065 | 34.719 | 0.7731 | Yes | ||
19 | 10921 | "RNPS1 (RNA binding protein S1, serine-rich domain)" | 1107 | 33.536 | 0.7884 | Yes | ||
20 | 11338 | U2AF2 (U2 small nuclear RNA auxiliary factor 2) | 1112 | 33.372 | 0.8056 | Yes | ||
21 | 65109 | UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast)) | 1778 | 21.341 | 0.7838 | No | ||
22 | 6429 | "SFRS4 (splicing factor, arginine/serine-rich 4)" | 1970 | 19.104 | 0.7843 | No | ||
23 | 51362 | CDC40 (cell division cycle 40 homolog (S. cerevisiae)) | 2098 | 17.942 | 0.7874 | No | ||
24 | 6431 | "SFRS6 (splicing factor, arginine/serine-rich 6)" | 2113 | 17.800 | 0.7959 | No | ||
25 | 29894 | "CPSF1 (cleavage and polyadenylation specific factor 1, 160kDa)" | 2720 | 12.711 | 0.7727 | No | ||
26 | 11051 | NUDT21 (nudix (nucleoside diphosphate linked moiety X)-type motif 21) | 3139 | 10.233 | 0.7574 | No | ||
27 | 51692 | "CPSF3 (cleavage and polyadenylation specific factor 3, 73kDa)" | 3299 | 9.533 | 0.7545 | No | ||
28 | 79869 | "FLJ12529 (pre-mRNA cleavage factor I, 59 kDa subunit)" | 3482 | 8.799 | 0.7501 | No | ||
29 | 10250 | SRRM1 (serine/arginine repetitive matrix 1) | 3484 | 8.795 | 0.7546 | No | ||
30 | 10914 | PAPOLA (poly(A) polymerase alpha) | 3875 | 7.187 | 0.7391 | No | ||
31 | 25888 | ZNF473 (zinc finger protein 473) | 4409 | 5.467 | 0.7156 | No | ||
32 | 1478 | "CSTF2 (cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa)" | 5494 | 3.074 | 0.6638 | No | ||
33 | 10978 | "CLP1 (CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae))" | 5783 | 2.637 | 0.6510 | No | ||
34 | 134353 | "LSM11 (LSM11, U7 small nuclear RNA associated)" | 6024 | 2.346 | 0.6403 | No | ||
35 | 8106 | "PABPN1 (poly(A) binding protein, nuclear 1)" | 9866 | 0.167 | 0.4511 | No | ||
36 | 9785 | DHX38 (DEAH (Asp-Glu-Ala-His) box polypeptide 38) | 14908 | -1.491 | 0.2033 | No | ||
37 | 53981 | "CPSF2 (cleavage and polyadenylation specific factor 2, 100kDa)" | 15120 | -1.654 | 0.1938 | No | ||
38 | 1477 | "CSTF1 (cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa)" | 18059 | -8.190 | 0.0532 | No | ||
39 | 8683 | "SFRS9 (splicing factor, arginine/serine-rich 9)" | 18964 | -16.250 | 0.0170 | No | ||
40 | 6637 | SNRPG (small nuclear ribonucleoprotein polypeptide G) | 19107 | -18.986 | 0.0199 | No | ||
41 | 51585 | "PCF11 (PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae))" | 19324 | -23.584 | 0.0215 | No | ||
42 | 6430 | "SFRS5 (splicing factor, arginine/serine-rich 5)" | 19923 | -53.636 | 0.0198 | No |