Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | GO|GO:0046930 |
Enrichment Score (ES) | 0.81917906 |
Normalized Enrichment Score (NES) | 1.6355402 |
Nominal p-value | 0.0 |
FDR q-value | 0.0356225 |
FWER p-Value | 0.866 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 5901 | "RAN (RAN, member RAS oncogene family)" | 27 | 250.127 | 0.1611 | Yes | ||
2 | 1984 | EIF5A (eukaryotic translation initiation factor 5A) | 68 | 172.120 | 0.2709 | Yes | ||
3 | 10204 | NUTF2 (nuclear transport factor 2) | 111 | 139.450 | 0.3594 | Yes | ||
4 | 3837 | KPNB1 (karyopherin (importin) beta 1) | 180 | 107.701 | 0.4260 | Yes | ||
5 | 57122 | NUP107 (nucleoporin 107kDa) | 276 | 89.588 | 0.4795 | Yes | ||
6 | 8480 | RAE1 (RAE1 RNA export 1 homolog (S. pombe)) | 322 | 83.312 | 0.5314 | Yes | ||
7 | 4085 | MAD2L1 (MAD2 mitotic arrest deficient-like 1 (yeast)) | 360 | 77.868 | 0.5801 | Yes | ||
8 | 11260 | "XPOT (exportin, tRNA (nuclear export receptor for tRNAs))" | 367 | 76.844 | 0.6297 | Yes | ||
9 | 81929 | SEH1L (SEH1-like (S. cerevisiae)) | 491 | 62.765 | 0.6644 | Yes | ||
10 | 7416 | VDAC1 (voltage-dependent anion channel 1) | 766 | 46.382 | 0.6811 | Yes | ||
11 | 79023 | NUP37 (nucleoporin 37kDa) | 770 | 46.189 | 0.7109 | Yes | ||
12 | 55706 | TMEM48 (transmembrane protein 48) | 806 | 44.541 | 0.7381 | Yes | ||
13 | 10527 | IPO7 (importin 7) | 886 | 41.082 | 0.7609 | Yes | ||
14 | 23636 | NUP62 (nucleoporin 62kDa) | 980 | 37.692 | 0.7808 | Yes | ||
15 | 79711 | IPO4 (importin 4) | 1030 | 35.811 | 0.8016 | Yes | ||
16 | 23165 | NUP205 (nucleoporin 205kDa) | 1143 | 32.605 | 0.8173 | Yes | ||
17 | 596 | BCL2 (B-cell CLL/lymphoma 2) | 1760 | 21.505 | 0.8009 | Yes | ||
18 | 23279 | NUP160 (nucleoporin 160kDa) | 1804 | 20.988 | 0.8124 | Yes | ||
19 | 5903 | RANBP2 (RAN binding protein 2) | 2164 | 17.399 | 0.8060 | Yes | ||
20 | 581 | BAX (BCL2-associated X protein) | 2225 | 16.869 | 0.8140 | Yes | ||
21 | 3843 | IPO5 (importin 5) | 2329 | 15.804 | 0.8192 | Yes | ||
22 | 55746 | NUP133 (nucleoporin 133kDa) | 2787 | 12.281 | 0.8046 | No | ||
23 | 5905 | RANGAP1 (Ran GTPase activating protein 1) | 2997 | 11.060 | 0.8015 | No | ||
24 | 79902 | NUP85 (nucleoporin 85kDa) | 3289 | 9.586 | 0.7934 | No | ||
25 | 348995 | NUP43 (nucleoporin 43kDa) | 3355 | 9.350 | 0.7963 | No | ||
26 | 7341 | SUMO1 (SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)) | 3657 | 8.157 | 0.7867 | No | ||
27 | 25909 | AHCTF1 (AT hook containing transcription factor 1) | 4464 | 5.335 | 0.7505 | No | ||
28 | 8379 | MAD1L1 (MAD1 mitotic arrest deficient-like 1 (yeast)) | 4753 | 4.581 | 0.7392 | No | ||
29 | 23039 | XPO7 (exportin 7) | 4783 | 4.527 | 0.7407 | No | ||
30 | 4928 | NUP98 (nucleoporin 98kDa) | 5721 | 2.716 | 0.6963 | No | ||
31 | 578 | BAK1 (BCL2-antagonist/killer 1) | 6428 | 1.851 | 0.6627 | No | ||
32 | 59343 | SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2) | 11845 | -0.290 | 0.3959 | No | ||
33 | 731 | "C8A (complement component 8, alpha polypeptide)" | 13075 | -0.630 | 0.3358 | No | ||
34 | 3267 | HRB (HIV-1 Rev binding protein) | 15546 | -2.007 | 0.2153 | No | ||
35 | 64901 | RANBP17 (RAN binding protein 17) | 16198 | -2.754 | 0.1850 | No | ||
36 | 8658 | "TNKS (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase)" | 16951 | -4.120 | 0.1506 | No | ||
37 | 8086 | "AAAS (achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A))" | 16985 | -4.211 | 0.1517 | No | ||
38 | 7175 | TPR (translocated promoter region (to activated MET oncogene)) | 17416 | -5.336 | 0.1340 | No | ||
39 | 6396 | SEC13 (SEC13 homolog (S. cerevisiae)) | 18834 | -14.381 | 0.0735 | No |