Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetPATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA|BMP RECEPTOR SIGNALING
Enrichment Score (ES)-0.7195168
Normalized Enrichment Score (NES)-1.6264127
Nominal p-value0.015243903
FDR q-value0.2565163
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA|BMP RECEPTOR SIGNALING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1657"BMPR1A (bone morphogenetic protein receptor, type IA)"216817.378-0.0778No
210468FST (follistatin)307210.587-0.1046No
36885MAP3K7 (mitogen-activated protein kinase kinase kinase 7)34089.133-0.1058No
44092SMAD7 (SMAD family member 7)43185.717-0.1410No
59765"ZFYVE16 (zinc finger, FYVE domain containing 16)"44705.329-0.1395No
656963"RGMA (RGM domain family, member A)"45435.124-0.1345No
757154SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)48364.388-0.1415No
84090SMAD5 (SMAD family member 5)49824.072-0.1419No
910217"CTDSPL (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like)"51083.800-0.1417No
104093SMAD9 (SMAD family member 9)52273.546-0.1415No
1164750SMURF2 (SMAD specific E3 ubiquitin protein ligase 2)68201.493-0.2175No
129350"CER1 (cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis))"70231.334-0.2252No
13197AHSG (alpha-2-HS-glycoprotein)71511.229-0.2294No
149241NOG (noggin)78830.792-0.2642No
152932GSK3B (glycogen synthase kinase 3 beta)80180.725-0.2695No
164086SMAD1 (SMAD family member 1)87060.479-0.3026No
17148738HFE2 (hemochromatosis type 2 (juvenile))100380.124-0.3680No
184089SMAD4 (SMAD family member 4)10664-0.017-0.3988No
198646CHRD (chordin)10767-0.040-0.4038No
2091851CHRDL1 (chordin-like 1)10806-0.049-0.4056No
2125928SOSTDC1 (sclerostin domain containing 1)11292-0.162-0.4292No
2226585"GREM1 (gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis))"11493-0.211-0.4387No
2323645"PPP1R15A (protein phosphatase 1, regulatory (inhibitor) subunit 15A)"14285-1.125-0.5744No
24650BMP2 (bone morphogenetic protein 2)14423-1.193-0.5792No
25654BMP6 (bone morphogenetic protein 6)14674-1.340-0.5893No
2610454MAP3K7IP1 (mitogen-activated protein kinase kinase kinase 7 interacting protein 1)14980-1.550-0.6017No
278021NUP214 (nucleoporin 214kDa)16014-2.513-0.6484No
2823118MAP3K7IP2 (mitogen-activated protein kinase kinase kinase 7 interacting protein 2)16913-4.022-0.6859No
29285704"RGMB (RGM domain family, member B)"17595-5.989-0.7095Yes
305494"PPM1A (protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform)"17598-6.003-0.6995Yes
315594MAPK1 (mitogen-activated protein kinase 1)18001-7.922-0.7061Yes
32658"BMPR1B (bone morphogenetic protein receptor, type IB)"18057-8.183-0.6951Yes
33659"BMPR2 (bone morphogenetic protein receptor, type II (serine/threonine kinase))"18100-8.454-0.6830Yes
34652BMP4 (bone morphogenetic protein 4)18378-10.143-0.6797Yes
354091SMAD6 (SMAD family member 6)18569-11.753-0.6693Yes
365499"PPP1CA (protein phosphatase 1, catalytic subunit, alpha isoform)"18582-11.854-0.6501Yes
376497SKI (v-ski sarcoma viral oncogene homolog (avian))18818-14.221-0.6378Yes
38331XIAP (X-linked inhibitor of apoptosis)19246-21.495-0.6229Yes
39655BMP7 (bone morphogenetic protein 7)19353-24.367-0.5873Yes
4058190"CTDSP1 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1)"19546-29.714-0.5470Yes
4110106"CTDSP2 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2)"19706-37.333-0.4923Yes
4225805BAMBI (BMP and activin membrane-bound inhibitor homolog (Xenopus laevis))20317-312.0360.0004Yes
Table: GSEA details [plain text format]



Fig 2: PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA|BMP RECEPTOR SIGNALING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA|BMP RECEPTOR SIGNALING: Random ES distribution   
Gene set null distribution of ES for PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA|BMP RECEPTOR SIGNALING