Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | GO|GO:0006353 |
Enrichment Score (ES) | 0.74868757 |
Normalized Enrichment Score (NES) | 1.6642777 |
Nominal p-value | 0.0014367816 |
FDR q-value | 0.023403937 |
FWER p-Value | 0.564 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 6432 | "SFRS7 (splicing factor, arginine/serine-rich 7, 35kDa)" | 38 | 213.976 | 0.0809 | Yes | ||
2 | 6635 | SNRPE (small nuclear ribonucleoprotein polypeptide E) | 43 | 207.433 | 0.1610 | Yes | ||
3 | 6636 | SNRPF (small nuclear ribonucleoprotein polypeptide F) | 93 | 154.388 | 0.2183 | Yes | ||
4 | 6426 | "SFRS1 (splicing factor, arginine/serine-rich 1)" | 119 | 133.017 | 0.2685 | Yes | ||
5 | 10189 | THOC4 (THO complex 4) | 158 | 117.078 | 0.3120 | Yes | ||
6 | 6634 | SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide 18kDa) | 196 | 103.434 | 0.3502 | Yes | ||
7 | 9939 | RBM8A (RNA binding motif protein 8A) | 201 | 102.613 | 0.3897 | Yes | ||
8 | 6427 | "SFRS2 (splicing factor, arginine/serine-rich 2)" | 273 | 90.107 | 0.4210 | Yes | ||
9 | 6428 | "SFRS3 (splicing factor, arginine/serine-rich 3)" | 302 | 85.664 | 0.4528 | Yes | ||
10 | 2966 | "GTF2H2 (general transcription factor IIH, polypeptide 2, 44kDa)" | 337 | 80.980 | 0.4825 | Yes | ||
11 | 7307 | U2AF1 (U2 small nuclear RNA auxiliary factor 1) | 509 | 61.555 | 0.4978 | Yes | ||
12 | 5435 | POLR2F (polymerase (RNA) II (DNA directed) polypeptide F) | 531 | 60.346 | 0.5201 | Yes | ||
13 | 902 | CCNH (cyclin H) | 536 | 59.543 | 0.5430 | Yes | ||
14 | 5441 | "POLR2L (polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa)" | 655 | 51.833 | 0.5572 | Yes | ||
15 | 6628 | SNRPB (small nuclear ribonucleoprotein polypeptides B and B1) | 697 | 49.717 | 0.5744 | Yes | ||
16 | 1479 | "CSTF3 (cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa)" | 767 | 46.272 | 0.5889 | Yes | ||
17 | 4686 | "NCBP1 (nuclear cap binding protein subunit 1, 80kDa)" | 860 | 42.266 | 0.6007 | Yes | ||
18 | 84172 | "POLR1B (polymerase (RNA) I polypeptide B, 128kDa)" | 925 | 39.618 | 0.6129 | Yes | ||
19 | 7884 | SLBP (stem-loop binding protein) | 966 | 37.985 | 0.6256 | Yes | ||
20 | 22916 | "NCBP2 (nuclear cap binding protein subunit 2, 20kDa)" | 986 | 37.528 | 0.6392 | Yes | ||
21 | 4116 | "MAGOH (mago-nashi homolog, proliferation-associated (Drosophila))" | 1009 | 36.619 | 0.6523 | Yes | ||
22 | 9295 | "SFRS11 (splicing factor, arginine/serine-rich 11)" | 1042 | 35.388 | 0.6644 | Yes | ||
23 | 84967 | "LSM10 (LSM10, U7 small nuclear RNA associated)" | 1065 | 34.719 | 0.6768 | Yes | ||
24 | 10921 | "RNPS1 (RNA binding protein S1, serine-rich domain)" | 1107 | 33.536 | 0.6877 | Yes | ||
25 | 11338 | U2AF2 (U2 small nuclear RNA auxiliary factor 2) | 1112 | 33.372 | 0.7004 | Yes | ||
26 | 2967 | "GTF2H3 (general transcription factor IIH, polypeptide 3, 34kDa)" | 1273 | 29.625 | 0.7040 | Yes | ||
27 | 10621 | "POLR3F (polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa)" | 1310 | 28.824 | 0.7134 | Yes | ||
28 | 5434 | "POLR2E (polymerase (RNA) II (DNA directed) polypeptide E, 25kDa)" | 1328 | 28.268 | 0.7235 | Yes | ||
29 | 8458 | "TTF2 (transcription termination factor, RNA polymerase II)" | 1461 | 26.080 | 0.7270 | Yes | ||
30 | 7270 | "TTF1 (transcription termination factor, RNA polymerase I)" | 1645 | 23.279 | 0.7270 | Yes | ||
31 | 65109 | UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast)) | 1778 | 21.341 | 0.7287 | Yes | ||
32 | 171568 | POLR3H (polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)) | 1917 | 19.810 | 0.7296 | Yes | ||
33 | 6429 | "SFRS4 (splicing factor, arginine/serine-rich 4)" | 1970 | 19.104 | 0.7344 | Yes | ||
34 | 55718 | POLR3E (polymerase (RNA) III (DNA directed) polypeptide E (80kD)) | 1982 | 18.997 | 0.7412 | Yes | ||
35 | 51362 | CDC40 (cell division cycle 40 homolog (S. cerevisiae)) | 2098 | 17.942 | 0.7425 | Yes | ||
36 | 6431 | "SFRS6 (splicing factor, arginine/serine-rich 6)" | 2113 | 17.800 | 0.7487 | Yes | ||
37 | 661 | "POLR3D (polymerase (RNA) III (DNA directed) polypeptide D, 44kDa)" | 2294 | 16.096 | 0.7460 | No | ||
38 | 29894 | "CPSF1 (cleavage and polyadenylation specific factor 1, 160kDa)" | 2720 | 12.711 | 0.7300 | No | ||
39 | 55703 | POLR3B (polymerase (RNA) III (DNA directed) polypeptide B) | 2743 | 12.558 | 0.7337 | No | ||
40 | 11051 | NUDT21 (nudix (nucleoside diphosphate linked moiety X)-type motif 21) | 3139 | 10.233 | 0.7182 | No | ||
41 | 51692 | "CPSF3 (cleavage and polyadenylation specific factor 3, 73kDa)" | 3299 | 9.533 | 0.7140 | No | ||
42 | 25885 | "POLR1A (polymerase (RNA) I polypeptide A, 194kDa)" | 3367 | 9.298 | 0.7143 | No | ||
43 | 2968 | "GTF2H4 (general transcription factor IIH, polypeptide 4, 52kDa)" | 3416 | 9.103 | 0.7155 | No | ||
44 | 9533 | "POLR1C (polymerase (RNA) I polypeptide C, 30kDa)" | 3463 | 8.873 | 0.7166 | No | ||
45 | 79869 | "FLJ12529 (pre-mRNA cleavage factor I, 59 kDa subunit)" | 3482 | 8.799 | 0.7191 | No | ||
46 | 10250 | SRRM1 (serine/arginine repetitive matrix 1) | 3484 | 8.795 | 0.7225 | No | ||
47 | 4331 | "MNAT1 (menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis))" | 3583 | 8.417 | 0.7209 | No | ||
48 | 10914 | PAPOLA (poly(A) polymerase alpha) | 3875 | 7.187 | 0.7093 | No | ||
49 | 9014 | "TAF1B (TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa)" | 4164 | 6.213 | 0.6975 | No | ||
50 | 25888 | ZNF473 (zinc finger protein 473) | 4409 | 5.467 | 0.6876 | No | ||
51 | 9015 | "TAF1A (TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa)" | 4498 | 5.251 | 0.6853 | No | ||
52 | 5437 | POLR2H (polymerase (RNA) II (DNA directed) polypeptide H) | 4596 | 5.000 | 0.6824 | No | ||
53 | 2068 | "ERCC2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)" | 5159 | 3.702 | 0.6561 | No | ||
54 | 11128 | "POLR3A (polymerase (RNA) III (DNA directed) polypeptide A, 155kDa)" | 5318 | 3.365 | 0.6496 | No | ||
55 | 1478 | "CSTF2 (cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa)" | 5494 | 3.074 | 0.6421 | No | ||
56 | 7978 | MTERF (mitochondrial transcription termination factor) | 5715 | 2.725 | 0.6323 | No | ||
57 | 7343 | "UBTF (upstream binding transcription factor, RNA polymerase I)" | 5733 | 2.704 | 0.6325 | No | ||
58 | 9013 | "TAF1C (TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa)" | 5768 | 2.664 | 0.6319 | No | ||
59 | 10978 | "CLP1 (CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae))" | 5783 | 2.637 | 0.6322 | No | ||
60 | 2071 | "ERCC3 (excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing))" | 5944 | 2.439 | 0.6252 | No | ||
61 | 134353 | "LSM11 (LSM11, U7 small nuclear RNA associated)" | 6024 | 2.346 | 0.6223 | No | ||
62 | 2965 | "GTF2H1 (general transcription factor IIH, polypeptide 1, 62kDa)" | 6155 | 2.163 | 0.6167 | No | ||
63 | 5440 | "POLR2K (polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa)" | 6321 | 1.970 | 0.6093 | No | ||
64 | 284119 | PTRF (polymerase I and transcript release factor) | 6507 | 1.780 | 0.6008 | No | ||
65 | 11178 | "LZTS1 (leucine zipper, putative tumor suppressor 1)" | 7040 | 1.317 | 0.5751 | No | ||
66 | 8106 | "PABPN1 (poly(A) binding protein, nuclear 1)" | 9866 | 0.167 | 0.4356 | No | ||
67 | 9785 | DHX38 (DEAH (Asp-Glu-Ala-His) box polypeptide 38) | 14908 | -1.491 | 0.1873 | No | ||
68 | 53981 | "CPSF2 (cleavage and polyadenylation specific factor 2, 100kDa)" | 15120 | -1.654 | 0.1775 | No | ||
69 | 1477 | "CSTF1 (cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa)" | 18059 | -8.190 | 0.0356 | No | ||
70 | 51082 | "POLR1D (polymerase (RNA) I polypeptide D, 16kDa)" | 18825 | -14.301 | 0.0033 | No | ||
71 | 8683 | "SFRS9 (splicing factor, arginine/serine-rich 9)" | 18964 | -16.250 | 0.0028 | No | ||
72 | 6637 | SNRPG (small nuclear ribonucleoprotein polypeptide G) | 19107 | -18.986 | 0.0031 | No | ||
73 | 51585 | "PCF11 (PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae))" | 19324 | -23.584 | 0.0016 | No | ||
74 | 4150 | MAZ (MYC-associated zinc finger protein (purine-binding transcription factor)) | 19553 | -29.999 | 0.0019 | No | ||
75 | 1022 | CDK7 (cyclin-dependent kinase 7) | 19757 | -39.600 | 0.0072 | No | ||
76 | 6430 | "SFRS5 (splicing factor, arginine/serine-rich 5)" | 19923 | -53.636 | 0.0199 | No |