Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classtreated
GeneSetGO|GO:0006399
Enrichment Score (ES)0.78943497
Normalized Enrichment Score (NES)1.7156017
Nominal p-value0.0
FDR q-value0.0093294205
FWER p-Value0.112
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0006399   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
13735KARS (lysyl-tRNA synthetase)40210.7150.0960Yes
23376IARS (isoleucyl-tRNA synthetase)127127.8060.1512Yes
34677NARS (asparaginyl-tRNA synthetase)181107.3440.1986Yes
42617GARS (glycyl-tRNA synthetase)210101.5320.2444Yes
56301SARS (seryl-tRNA synthetase)29486.3830.2805Yes
65464PPA1 (pyrophosphatase (inorganic) 1)30584.8010.3194Yes
79255"SCYE1 (small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating))"38474.8060.3504Yes
86741SSB (Sjogren syndrome antigen B (autoantigen La))39073.8580.3845Yes
92193"FARSA (phenylalanyl-tRNA synthetase, alpha subunit)"41770.5670.4160Yes
1055699"IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)"45366.1120.4451Yes
1179731"NARS2 (asparaginyl-tRNA synthetase 2, mitochondrial (putative))"46764.8590.4746Yes
127965JTV1 (JTV1 gene)48563.4500.5033Yes
1310056"FARSB (phenylalanyl-tRNA synthetase, beta subunit)"49362.3880.5319Yes
146897TARS (threonyl-tRNA synthetase)56857.5050.5550Yes
159521EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1)66251.3930.5743Yes
1651095"TRNT1 (tRNA nucleotidyl transferase, CCA-adding, 1)"66451.2050.5981Yes
173035HARS (histidyl-tRNA synthetase)72048.2410.6178Yes
18283989TSEN54 (tRNA splicing endonuclease 54 homolog (S. cerevisiae))89040.9180.6285Yes
194234METTL1 (methyltransferase like 1)91340.2020.6461Yes
208565YARS (tyrosyl-tRNA synthetase)105735.0650.6554Yes
2180324PUS1 (pseudouridylate synthase 1)106634.6890.6711Yes
227453WARS (tryptophanyl-tRNA synthetase)106934.5810.6871Yes
2354888"NSUN2 (NOL1/NOP2/Sun domain family, member 2)"116132.0540.6975Yes
2451520LARS (leucyl-tRNA synthetase)119431.2420.7105Yes
2551493C22orf28 (chromosome 22 open reading frame 28)139027.1850.7135Yes
265917RARS (arginyl-tRNA synthetase)144026.3950.7234Yes
27283459"GATC (glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial))"155124.6610.7294Yes
28124454"EARS2 (glutamyl-tRNA synthetase 2, mitochondrial (putative))"155624.5570.7406Yes
2981605URM1 (ubiquitin related modifier 1 homolog (S. cerevisiae))165723.1360.7465Yes
3010785WDR4 (WD repeat domain 4)173221.9740.7530Yes
311615DARS (aspartyl-tRNA synthetase)178421.3110.7604Yes
3223536"ADAT1 (adenosine deaminase, tRNA-specific 1)"187420.1960.7654Yes
3380746TSEN2 (tRNA splicing endonuclease 2 homolog (S. cerevisiae))191319.8420.7728Yes
3416AARS (alanyl-tRNA synthetase)202718.5290.7758Yes
3510667"FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial)"215817.4460.7775Yes
3654974THG1L (tRNA-histidine guanylyltransferase 1-like (S. cerevisiae))226616.4100.7799Yes
3751067"YARS2 (tyrosyl-tRNA synthetase 2, mitochondrial)"238115.2820.7813Yes
382058EPRS (glutamyl-prolyl-tRNA synthetase)242214.9580.7863Yes
394141MARS (methionyl-tRNA synthetase)249514.3130.7894Yes
40348180C16orf84 (chromosome 16 open reading frame 84)264313.1270.7883No
4157038"RARS2 (arginyl-tRNA synthetase 2, mitochondrial)"294811.3400.7786No
4279691QTRTD1 (queuine tRNA-ribosyltransferase domain containing 1)298311.1000.7820No
4327304MOCS3 (molybdenum cofactor synthesis 3)313510.2570.7794No
4479587"CARS2 (cysteinyl-tRNA synthetase 2, mitochondrial (putative))"32159.8800.7801No
4510352"WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial)"32269.8230.7841No
467407VARS (valyl-tRNA synthetase)32669.6600.7867No
4757176"VARS2 (valyl-tRNA synthetase 2, mitochondrial (putative))"33429.3810.7874No
4810940"POP1 (processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae))"35708.4680.7801No
4927068PPA2 (pyrophosphatase (inorganic) 2)39486.9640.7647No
5055157"DARS2 (aspartyl-tRNA synthetase 2, mitochondrial)"39736.8770.7667No
5123395"LARS2 (leucyl-tRNA synthetase 2, mitochondrial)"46094.9480.7377No
5281890QTRT1 (queuine tRNA-ribosyltransferase 1)54383.1760.6983No
5380222"TARS2 (threonyl-tRNA synthetase 2, mitochondrial (putative))"55093.0500.6963No
5410978"CLP1 (CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae))"57832.6370.6840No
5557505"AARS2 (alanyl-tRNA synthetase 2, mitochondrial (putative))"58492.5520.6820No
5655278QRSL1 (glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1)61542.1650.6680No
5792935"MARS2 (methionyl-tRNA synthetase 2, mitochondrial)"63321.9570.6602No
5855687TRMU (tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase)66831.6070.6436No
5954802TRIT1 (tRNA isopentenyltransferase 1)70321.3240.6271No
60129450C2orf60 (chromosome 2 open reading frame 60)12356-0.4160.3645No
6191801"ALKBH8 (alkB, alkylation repair homolog 8 (E. coli))"15416-1.8850.2144No
6225973"PARS2 (prolyl-tRNA synthetase 2, mitochondrial (putative))"15762-2.2230.1984No
6354938"SARS2 (seryl-tRNA synthetase 2, mitochondrial)"16128-2.6720.1816No
645188PET112L (PET112-like (yeast))16674-3.5490.1564No
6523438"HARS2 (histidyl-tRNA synthetase 2, mitochondrial (putative))"17469-5.5230.1198No
66833CARS (cysteinyl-tRNA synthetase)19280-22.4110.0408No
675859QARS (glutaminyl-tRNA synthetase)19303-22.9780.0504No
Table: GSEA details [plain text format]



Fig 2: GO|GO:0006399   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0006399: Random ES distribution   
Gene set null distribution of ES for GO|GO:0006399