Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0045165
Enrichment Score (ES)-0.7014592
Normalized Enrichment Score (NES)-1.7246374
Nominal p-value0.0
FDR q-value0.11320829
FWER p-Value0.774
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0045165   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
11499"CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa)"48063.9320.0260No
29314KLF4 (Kruppel-like factor 4 (gut))83143.4670.0425No
32296FOXC1 (forkhead box C1)223816.764-0.0139No
4429ASCL1 (achaete-scute complex homolog 1 (Drosophila))246214.694-0.0135No
57855FZD5 (frizzled homolog 5 (Drosophila))277112.344-0.0191No
63475IFRD1 (interferon-related developmental regulator 1)286311.892-0.0143No
74087SMAD2 (SMAD family member 2)32089.912-0.0236No
88324FZD7 (frizzled homolog 7 (Drosophila))33609.324-0.0238No
97479"WNT8B (wingless-type MMTV integration site family, member 8B)"47184.675-0.0872No
103207HOXA11 (homeobox A11)47204.672-0.0836No
116662SOX9 (SRY (sex determining region Y)-box 9)52043.599-0.1047No
128312AXIN1 (axin 1)52533.490-0.1044No
132623GATA1 (GATA binding protein 1 (globin transcription factor 1))56482.850-0.1216No
142263FGFR2 (fibroblast growth factor receptor 2)60012.374-0.1371No
156886TAL1 (T-cell acute lymphocytic leukemia 1)61652.156-0.1435No
167473"WNT3 (wingless-type MMTV integration site family, member 3)"64681.804-0.1570No
174656MYOG (myogenin (myogenic factor 4))68371.474-0.1741No
187478"WNT8A (wingless-type MMTV integration site family, member 8A)"70191.336-0.1820No
19149233IL23R (interleukin 23 receptor)72281.174-0.1913No
20388585HES5 (hairy and enhancer of split 5 (Drosophila))73651.087-0.1972No
2157453DSCAML1 (Down syndrome cell adhesion molecule like 1)74451.037-0.2003No
224618MYF6 (myogenic factor 6 (herculin))77670.856-0.2155No
236657SOX2 (SRY (sex determining region Y)-box 2)80200.724-0.2274No
247482"WNT2B (wingless-type MMTV integration site family, member 2B)"81840.658-0.2349No
2530812SOX8 (SRY (sex determining region Y)-box 8)82530.631-0.2378No
267490WT1 (Wilms tumor 1)85590.526-0.2525No
276299SALL1 (sal-like 1 (Drosophila))86490.497-0.2565No
282299FOXI1 (forkhead box I1)91680.342-0.2818No
292139EYA2 (eyes absent homolog 2 (Drosophila))93000.305-0.2880No
306997TDGF1 (teratocarcinoma-derived growth factor 1)94750.260-0.2964No
315076PAX2 (paired box 2)96030.228-0.3025No
326495SIX1 (SIX homeobox 1)98910.159-0.3166No
334617MYF5 (myogenic factor 5)99080.156-0.3172No
3479923NANOG (Nanog homeobox)99230.151-0.3178No
353670ISL1 (ISL LIM homeobox 1)10817-0.051-0.3619No
3664321SOX17 (SRY (sex determining region Y)-box 17)11243-0.153-0.3828No
372303"FOXC2 (forkhead box C2 (MFH-1, mesenchyme forkhead 1))"11316-0.168-0.3862No
383171FOXA3 (forkhead box A3)11323-0.170-0.3864No
393593"IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))"11374-0.185-0.3887No
402307FOXS1 (forkhead box S1)11488-0.211-0.3941No
414654MYOD1 (myogenic differentiation 1)11595-0.233-0.3992No
4228514DLL1 (delta-like 1 (Drosophila))11811-0.283-0.4096No
431848DUSP6 (dual specificity phosphatase 6)11822-0.286-0.4098No
447471"WNT1 (wingless-type MMTV integration site family, member 1)"12102-0.347-0.4233No
4511281POU6F2 (POU class 6 homeobox 2)12655-0.500-0.4502No
467472WNT2 (wingless-type MMTV integration site family member 2)12752-0.529-0.4546No
475468PPARG (peroxisome proliferator-activated receptor gamma)12768-0.534-0.4549No
4856603"CYP26B1 (cytochrome P450, family 26, subfamily B, polypeptide 1)"12892-0.573-0.4605No
495457POU4F1 (POU class 4 homeobox 1)12937-0.587-0.4622No
502247FGF2 (fibroblast growth factor 2 (basic))13137-0.649-0.4716No
515460POU5F1 (POU class 5 homeobox 1)13341-0.718-0.4810No
523170FOXA2 (forkhead box A2)13351-0.723-0.4809No
534855NOTCH4 (Notch homolog 4 (Drosophila))13834-0.914-0.5040No
546469SHH (sonic hedgehog homolog (Drosophila))14133-1.064-0.5179No
554909NTF4 (neurotrophin 4)14196-1.086-0.5201No
56650BMP2 (bone morphogenetic protein 2)14423-1.193-0.5304No
574208MEF2C (myocyte enhancer factor 2C)14451-1.211-0.5307No
582736GLI2 (GLI-Kruppel family member GLI2)14561-1.273-0.5351No
5989870TRIM15 (tripartite motif-containing 15)14775-1.409-0.5446No
605080PAX6 (paired box 6)14826-1.435-0.5459No
616608SMO (smoothened homolog (Drosophila))14976-1.544-0.5521No
625629PROX1 (prospero homeobox 1)15044-1.592-0.5542No
633714JAG2 (jagged 2)15118-1.652-0.5565No
643594"IL12RB1 (interleukin 12 receptor, beta 1)"15945-2.429-0.5954No
656899TBX1 (T-box 1)16186-2.739-0.6051No
66182JAG1 (jagged 1 (Alagille syndrome))16647-3.487-0.6251No
676666SOX12 (SRY (sex determining region Y)-box 12)17154-4.635-0.6465No
6855897MESP1 (mesoderm posterior 1 homolog (mouse))17684-6.362-0.6677No
697046"TGFBR1 (transforming growth factor, beta receptor 1)"18051-8.147-0.6795No
70652BMP4 (bone morphogenetic protein 4)18378-10.143-0.6877No
71161882"ZFPM1 (zinc finger protein, multitype 1)"18444-10.759-0.6825No
722624GATA2 (GATA binding protein 2)18660-12.664-0.6833No
7351561"IL23A (interleukin 23, alpha subunit p19)"19029-17.353-0.6880Yes
742034EPAS1 (endothelial PAS domain protein 1)19065-18.219-0.6755Yes
754170MCL1 (myeloid cell leukemia sequence 1 (BCL2-related))19101-18.831-0.6626Yes
766929TCF3 (transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47))19423-26.298-0.6580Yes
777026"NR2F2 (nuclear receptor subfamily 2, group F, member 2)"19595-31.444-0.6420Yes
786934"TCF7L2 (transcription factor 7-like 2 (T-cell specific, HMG-box))"19726-38.340-0.6186Yes
793728JUP (junction plakoglobin)19987-61.273-0.5838Yes
804853NOTCH2 (Notch homolog 2 (Drosophila))20121-85.023-0.5242Yes
813398"ID2 (inhibitor of DNA binding 2, dominant negative helix-loop-helix protein)"20185-106.279-0.4446Yes
823169FOXA1 (forkhead box A1)20189-110.661-0.3587Yes
8322943DKK1 (dickkopf homolog 1 (Xenopus laevis))20301-214.170-0.1976Yes
842625GATA3 (GATA binding protein 3)20312-255.4990.0006Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0045165   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0045165: Random ES distribution   
Gene set null distribution of ES for GO|GO:0045165