Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos
Phenotype | Phenotype.cls#treated_versus_cont_repos
Upregulated in class | cont
GeneSet | MSIGDB_C2|BIOCARTA_CTL_PATHWAY
Enrichment Score (ES) | -0.90687823
Normalized Enrichment Score (NES) | -1.6621952
Nominal p-value | 0.0
FDR q-value | 0.18820529
FWER p-Value | 0.997
Table: GSEA Results Summary

Fig 1: Enrichment plot: MSIGDB_C2|BIOCARTA_CTL_PATHWAY
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
1 | 355 | "FAS (Fas (TNF receptor superfamily, member 6))" |  |  | 3802 | 7.517 | -0.1630 | No
2 | 6955 | TRA@ (T cell receptor alpha locus) |  |  | 6571 | 1.704 | -0.2938 | No
3 | 915 | "CD3D (CD3d molecule, delta (CD3-TCR complex))" |  |  | 8076 | 0.700 | -0.3655 | No
4 | 3683 | "ITGAL (integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide))" |  |  | 9123 | 0.352 | -0.4159 | No
5 | 356 | "FASLG (Fas ligand (TNF superfamily, member 6))" |  |  | 9155 | 0.344 | -0.4163 | No
6 | 5551 | PRF1 (perforin 1 (pore forming protein)) |  |  | 9314 | 0.302 | -0.4231 | No
7 | 919 | CD247 (CD247 molecule) |  |  | 9865 | 0.167 | -0.4497 | No
8 | 3002 | "GZMB (granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1))" |  |  | 10454 | 0.024 | -0.4785 | No
9 | 917 | "CD3G (CD3g molecule, gamma (CD3-TCR complex))" |  |  | 14522 | -1.255 | -0.6747 | No
10 | 3689 | "ITGB2 (integrin, beta 2 (complement component 3 receptor 3 and 4 subunit))" |  |  | 15270 | -1.772 | -0.7058 | No
11 | 916 | "CD3E (CD3e molecule, epsilon (CD3-TCR complex))" |  |  | 16842 | -3.845 | -0.7708 | No
12 | 3383 | ICAM1 (intercellular adhesion molecule 1) |  |  | 17688 | -6.391 | -0.7918 | Yes
13 | 3105 | "HLA-A (major histocompatibility complex, class I, A)" |  |  | 20027 | -65.132 | -0.6971 | Yes
14 | 567 | B2M (beta-2-microglobulin) |  |  | 20305 | -220.982 | 0.0010 | Yes
Table: GSEA details [plain text format]

Fig 2: MSIGDB_C2|BIOCARTA_CTL_PATHWAY
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: MSIGDB_C2|BIOCARTA_CTL_PATHWAY: Random ES distribution
Gene set null distribution of ES for MSIGDB_C2|BIOCARTA_CTL_PATHWAY