Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | GO|GO:0051341 |
Enrichment Score (ES) | 0.7478645 |
Normalized Enrichment Score (NES) | 1.57876 |
Nominal p-value | 0.0061919503 |
FDR q-value | 0.083851926 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 3320 | "HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1)" | 13 | 318.362 | 0.2394 | Yes | ||
2 | 3091 | "HIF1A (hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor))" | 46 | 196.008 | 0.3856 | Yes | ||
3 | 801 | "CALM1 (calmodulin 1 (phosphorylase kinase, delta))" | 100 | 147.662 | 0.4943 | Yes | ||
4 | 2717 | "GLA (galactosidase, alpha)" | 104 | 143.790 | 0.6026 | Yes | ||
5 | 805 | "CALM2 (calmodulin 2 (phosphorylase kinase, delta))" | 192 | 104.092 | 0.6767 | Yes | ||
6 | 2643 | GCH1 (GTP cyclohydrolase 1) | 456 | 65.524 | 0.7132 | Yes | ||
7 | 10434 | LYPLA1 (lysophospholipase I) | 598 | 55.248 | 0.7479 | Yes | ||
8 | 949 | "SCARB1 (scavenger receptor class B, member 1)" | 2018 | 18.608 | 0.6919 | No | ||
9 | 2395 | FXN (frataxin) | 2556 | 13.817 | 0.6758 | No | ||
10 | 340481 | "ZDHHC21 (zinc finger, DHHC-type containing 21)" | 2657 | 13.082 | 0.6808 | No | ||
11 | 857 | "CAV1 (caveolin 1, caveolae protein, 22kDa)" | 3406 | 9.137 | 0.6508 | No | ||
12 | 1594 | "CYP27B1 (cytochrome P450, family 27, subfamily B, polypeptide 1)" | 3417 | 9.100 | 0.6571 | No | ||
13 | 64127 | NOD2 (nucleotide-binding oligomerization domain containing 2) | 3594 | 8.389 | 0.6548 | No | ||
14 | 9722 | NOS1AP (nitric oxide synthase 1 (neuronal) adaptor protein) | 4113 | 6.400 | 0.6341 | No | ||
15 | 27 | "ABL2 (v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene))" | 4586 | 5.027 | 0.6146 | No | ||
16 | 2208 | "FCER2 (Fc fragment of IgE, low affinity II, receptor for (CD23))" | 5116 | 3.777 | 0.5913 | No | ||
17 | 1956 | "EGFR (epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian))" | 5292 | 3.407 | 0.5853 | No | ||
18 | 6622 | "SNCA (synuclein, alpha (non A4 component of amyloid precursor))" | 5512 | 3.048 | 0.5768 | No | ||
19 | 51070 | NOSIP (nitric oxide synthase interacting protein) | 5770 | 2.660 | 0.5661 | No | ||
20 | 3240 | HP (haptoglobin) | 6668 | 1.617 | 0.5231 | No | ||
21 | 3357 | HTR2B (5-hydroxytryptamine (serotonin) receptor 2B) | 7872 | 0.797 | 0.4643 | No | ||
22 | 348 | APOE (apolipoprotein E) | 8109 | 0.687 | 0.4532 | No | ||
23 | 2022 | ENG (endoglin (Osler-Rendu-Weber syndrome 1)) | 8423 | 0.570 | 0.4382 | No | ||
24 | 185 | "AGTR1 (angiotensin II receptor, type 1)" | 8893 | 0.418 | 0.4154 | No | ||
25 | 3458 | "IFNG (interferon, gamma)" | 9835 | 0.174 | 0.3691 | No | ||
26 | 3001 | "GZMA (granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3))" | 9848 | 0.171 | 0.3686 | No | ||
27 | 183 | "AGT (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))" | 10447 | 0.027 | 0.3392 | No | ||
28 | 186 | "AGTR2 (angiotensin II receptor, type 2)" | 11221 | -0.147 | 0.3011 | No | ||
29 | 1816 | DRD5 (dopamine receptor D5) | 11406 | -0.194 | 0.2922 | No | ||
30 | 3630 | INS (insulin) | 11442 | -0.201 | 0.2906 | No | ||
31 | 3553 | "IL1B (interleukin 1, beta)" | 11912 | -0.304 | 0.2677 | No | ||
32 | 7124 | "TNF (tumor necrosis factor (TNF superfamily, member 2))" | 12777 | -0.537 | 0.2255 | No | ||
33 | 4846 | NOS3 (nitric oxide synthase 3 (endothelial cell)) | 12844 | -0.558 | 0.2227 | No | ||
34 | 115677 | NOSTRIN (nitric oxide synthase trafficker) | 13592 | -0.812 | 0.1865 | No | ||
35 | 8074 | FGF23 (fibroblast growth factor 23) | 13596 | -0.815 | 0.1869 | No | ||
36 | 2668 | GDNF (glial cell derived neurotrophic factor) | 14268 | -1.116 | 0.1547 | No | ||
37 | 55217 | "TMLHE (trimethyllysine hydroxylase, epsilon)" | 15334 | -1.817 | 0.1035 | No | ||
38 | 2672 | GFI1 (growth factor independent 1 transcription repressor) | 15994 | -2.491 | 0.0729 | No | ||
39 | 51295 | ECSIT (ECSIT homolog (Drosophila)) | 16597 | -3.397 | 0.0458 | No | ||
40 | 4790 | NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) | 17493 | -5.614 | 0.0059 | No | ||
41 | 10013 | HDAC6 (histone deacetylase 6) | 17495 | -5.624 | 0.0100 | No | ||
42 | 7421 | "VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor)" | 17509 | -5.685 | 0.0137 | No | ||
43 | 1907 | EDN2 (endothelin 2) | 17877 | -7.211 | 0.0010 | No | ||
44 | 5447 | POR (P450 (cytochrome) oxidoreductase) | 18110 | -8.500 | -0.0040 | No | ||
45 | 808 | "CALM3 (calmodulin 3 (phosphorylase kinase, delta))" | 18186 | -8.961 | -0.0010 | No | ||
46 | 8976 | WASL (Wiskott-Aldrich syndrome-like) | 18399 | -10.347 | -0.0036 | No | ||
47 | 538 | "ATP7A (ATPase, Cu++ transporting, alpha polypeptide)" | 18547 | -11.483 | -0.0022 | No | ||
48 | 25 | "ABL1 (c-abl oncogene 1, receptor tyrosine kinase)" | 19023 | -17.240 | -0.0126 | No | ||
49 | 207 | AKT1 (v-akt murine thymoma viral oncogene homolog 1) | 19588 | -31.123 | -0.0170 | No | ||
50 | 1906 | EDN1 (endothelin 1) | 19645 | -33.953 | 0.0059 | No | ||
51 | 5018 | OXA1L (oxidase (cytochrome c) assembly 1-like) | 19696 | -36.657 | 0.0310 | No |