Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classtreated
GeneSetGO|GO:0006457
Enrichment Score (ES)0.7226094
Normalized Enrichment Score (NES)1.6682547
Nominal p-value0.0
FDR q-value0.023169575
FWER p-Value0.517
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0006457   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
13312HSPA8 (heat shock 70kDa protein 8)2503.3570.0902Yes
23329HSPD1 (heat shock 60kDa protein 1 (chaperonin))9347.5300.1523Yes
33320"HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1)"13318.3620.2093Yes
410576"CCT2 (chaperonin containing TCP1, subunit 2 (beta))"33226.6750.2490Yes
510376"TUBA1B (tubulin, alpha 1b)"39213.0030.2870Yes
622948"CCT5 (chaperonin containing TCP1, subunit 5 (epsilon))"53183.8340.3193Yes
710383"TUBB2C (tubulin, beta 2C)"67172.2020.3496Yes
83309"HSPA5 (heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa))"82160.8330.3777Yes
9821CANX (calnexin)94153.2340.4047Yes
1010575"CCT4 (chaperonin containing TCP1, subunit 4 (delta))"124128.9090.4264Yes
113303HSPA1A (heat shock 70kDa protein 1A)131125.6240.4486Yes
1210598"AHSA1 (AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast))"138123.8010.4705Yes
137846"TUBA1A (tubulin, alpha 1a)"155119.0960.4911Yes
1484790"TUBA1C (tubulin, alpha 1c)"163113.5430.5111Yes
157203"CCT3 (chaperonin containing TCP1, subunit 3 (gamma))"187105.7510.5290Yes
166950TCP1 (t-complex 1)200102.9170.5469Yes
176902TBCA (tubulin folding cofactor A)207101.9240.5648Yes
18908"CCT6A (chaperonin containing TCP1, subunit 6A (zeta 1))"22199.1290.5820Yes
1923184MESDC2 (mesoderm development candidate 2)22797.8520.5993Yes
205202PFDN2 (prefoldin subunit 2)31084.3220.6104Yes
2110856RUVBL2 (RuvB-like 2 (E. coli))36177.8370.6219Yes
2251022GLRX2 (glutaredoxin 2)36277.8040.6358Yes
239093"DNAJA3 (DnaJ (Hsp40) homolog, subfamily A, member 3)"41970.0000.6456Yes
2410381"TUBB3 (tubulin, beta 3)"50861.5660.6523Yes
259761KIAA0152 (KIAA0152)59055.8730.6583Yes
2684617"TUBB6 (tubulin, beta 6)"60754.5810.6673Yes
27811CALR (calreticulin)64452.3600.6749Yes
287466WFS1 (Wolfram syndrome 1 (wolframin))69050.1170.6817Yes
2910049"DNAJB6 (DnaJ (Hsp40) homolog, subfamily B, member 6)"71848.2800.6890Yes
3027000"DNAJC2 (DnaJ (Hsp40) homolog, subfamily C, member 2)"72448.0370.6974Yes
311861"TOR1A (torsin family 1, member A (torsin A))"74947.2680.7047Yes
3210471PFDN6 (prefoldin subunit 6)84343.0260.7078Yes
33573BAG1 (BCL2-associated athanogene)91040.2660.7118Yes
3480267"EDEM3 (ER degradation enhancer, mannosidase alpha-like 3)"94039.0250.7174Yes
357266"DNAJC7 (DnaJ (Hsp40) homolog, subfamily C, member 7)"97237.8590.7226Yes
3626973CHORDC1 (cysteine and histidine-rich domain (CHORD)-containing 1)120930.9400.7165No
379529BAG5 (BCL2-associated athanogene 5)131128.8160.7167No
387411VBP1 (von Hippel-Lindau binding protein 1)156424.4210.7086No
397280"TUBB2A (tubulin, beta 2A)"171622.1630.7051No
4051182HSPA14 (heat shock 70kDa protein 14)172222.0820.7088No
4126278SACS (spastic ataxia of Charlevoix-Saguenay (sacsin))176621.4520.7105No
423304HSPA1B (heat shock 70kDa protein 1B)184920.5000.7101No
436905TBCE (tubulin folding cofactor E)194819.4580.7088No
4410574"CCT7 (chaperonin containing TCP1, subunit 7 (eta))"196019.3180.7117No
4510728PTGES3 (prostaglandin E synthase 3 (cytosolic))200018.7710.7131No
469532BAG2 (BCL2-associated athanogene 2)201418.6560.7158No
478877SPHK1 (sphingosine kinase 1)247414.5880.6958No
4822926ATF6 (activating transcription factor 6)252814.0540.6957No
493337"DNAJB1 (DnaJ (Hsp40) homolog, subfamily B, member 1)"269712.8740.6897No
501155TBCB (tubulin folding cofactor B)274212.5590.6897No
5110130"PDIA6 (protein disulfide isomerase family A, member 6)"287411.8050.6854No
528195MKKS (McKusick-Kaufman syndrome)301610.9380.6804No
5323640HSPBP1 (hsp70-interacting protein)314810.1880.6757No
549695"EDEM1 (ER degradation enhancer, mannosidase alpha-like 1)"31969.9920.6752No
5522824HSPA4L (heat shock 70kDa protein 4-like)32799.6160.6728No
5655741"EDEM2 (ER degradation enhancer, mannosidase alpha-like 2)"33289.4420.6722No
577277"TUBA4A (tubulin, alpha 4a)"36508.1830.6577No
58113457"TUBA3D (tubulin, alpha 3d)"37697.6320.6533No
597265TTC1 (tetratricopeptide repeat domain 1)38667.2320.6498No
609531BAG3 (BCL2-associated athanogene 3)41296.3340.6380No
6184750"FUT10 (fucosyltransferase 10 (alpha (1,3) fucosyltransferase))"42276.0200.6343No
622923"PDIA3 (protein disulfide isomerase family A, member 3)"44555.3600.6240No
639530BAG4 (BCL2-associated athanogene 4)46074.9620.6174No
6430001ERO1L (ERO1-like (S. cerevisiae))46334.8930.6171No
657278"TUBA3C (tubulin, alpha 3c)"50443.9370.5975No
6679087"ALG12 (asparagine-linked glycosylation 12 homolog (S. cerevisiae, alpha-1,6-mannosyltransferase))"51583.7030.5926No
676903TBCC (tubulin folding cofactor C)53073.3730.5858No
6823071TXNDC4 (thioredoxin domain containing 4 (endoplasmic reticulum))54243.1930.5807No
6964714"PDIA2 (protein disulfide isomerase family A, member 2)"62412.0750.5407No
706102RP2 (retinitis pigmentosa 2 (X-linked recessive))64621.8090.5301No
713338"DNAJC4 (DnaJ (Hsp40) homolog, subfamily C, member 4)"65561.7240.5258No
721409"CRYAA (crystallin, alpha A)"67151.5850.5183No
7310694"CCT8 (chaperonin containing TCP1, subunit 8 (theta))"67731.5350.5157No
7481562"LMAN2L (lectin, mannose-binding 2-like)"68791.4300.5108No
7556604"TUBB4Q (tubulin, beta polypeptide 4, member Q)"69461.3800.5078No
768425LTBP4 (latent transforming growth factor beta binding protein 4)71611.2200.4974No
7711328"FKBP9 (FK506 binding protein 9, 63 kDa)"82630.6270.4431No
7855757UGCGL2 (UDP-glucose ceramide glucosyltransferase-like 2)88660.4260.4134No
79347733"TUBB2B (tubulin, beta 2B)"95320.2470.3805No
8010382"TUBB4 (tubulin, beta 4)"100210.1290.3564No
81336APOA2 (apolipoprotein A-II)11062-0.1090.3049No
8281027"TUBB1 (tubulin, beta 1)"11424-0.1970.2871No
8356605ERO1LB (ERO1-like beta (S. cerevisiae))12241-0.3840.2468No
845589PRKCSH (protein kinase C substrate 80K-H)13559-0.7990.1818No
851410"CRYAB (crystallin, alpha B)"14218-1.0960.1494No
862281"FKBP1B (FK506 binding protein 1B, 12.6 kDa)"14286-1.1250.1463No
872280"FKBP1A (FK506 binding protein 1A, 12kDa)"14371-1.1690.1424No
88957ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5)14439-1.2050.1393No
89131118"DNAJC19 (DnaJ (Hsp40) homolog, subfamily C, member 19)"15396-1.8660.0923No
90325"APCS (amyloid P component, serum)"15845-2.3020.0706No
9110954"PDIA5 (protein disulfide isomerase family A, member 5)"16388-3.0390.0443No
9210026"PIGK (phosphatidylinositol glycan anchor biosynthesis, class K)"16399-3.0600.0443No
934043LRPAP1 (low density lipoprotein receptor-related protein associated protein 1)17295-4.9650.0010No
945201PFDN1 (prefoldin subunit 1)17382-5.230-0.0024No
957841GCS1 (glucosidase I)17454-5.473-0.0049No
96134218"DNAJC21 (DnaJ (Hsp40) homolog, subfamily C, member 21)"17678-6.356-0.0148No
9756886UGCGL1 (UDP-glucose ceramide glucosyltransferase-like 1)17723-6.552-0.0158No
989526MPDU1 (mannose-P-dolichol utilization defect 1)17893-7.334-0.0228No
9911253"MAN1B1 (mannosidase, alpha, class 1B, member 1)"18177-8.898-0.0352No
1009403SEP15 (15 kDa selenoprotein)18333-9.815-0.0411No
1014802"NFYC (nuclear transcription factor Y, gamma)"18389-10.242-0.0420No
1026904TBCD (tubulin folding cofactor D)18522-11.302-0.0465No
10364374"SIL1 (SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae))"19176-20.105-0.0752No
1045768QSOX1 (quiescin Q6 sulfhydryl oxidase 1)19195-20.482-0.0724No
1059049AIP (aryl hydrocarbon receptor interacting protein)19291-22.850-0.0730No
10623193"GANAB (glucosidase, alpha; neutral AB)"19330-23.729-0.0707No
10710961ERP29 (endoplasmic reticulum protein 29)19551-29.940-0.0762No
1085203PFDN4 (prefoldin subunit 4)19590-31.197-0.0725No
1095204PFDN5 (prefoldin subunit 5)19784-41.441-0.0746No
1103998"LMAN1 (lectin, mannose-binding, 1)"19954-57.564-0.0726No
1111201"CLN3 (ceroid-lipofuscinosis, neuronal 3)"19985-61.160-0.0631No
1125478PPIA (peptidylprolyl isomerase A (cyclophilin A))20198-115.647-0.0529No
1131191CLU (clusterin)20222-127.685-0.0311No
11460"ACTB (actin, beta)"20292-201.3250.0016No
Table: GSEA details [plain text format]



Fig 2: GO|GO:0006457   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0006457: Random ES distribution   
Gene set null distribution of ES for GO|GO:0006457