Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0007179
Enrichment Score (ES)-0.62338775
Normalized Enrichment Score (NES)-1.5709131
Nominal p-value0.009868421
FDR q-value0.3081151
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0007179   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
123089PEG10 (paternally expressed 10)51961.2280.0168No
27071KLF10 (Kruppel-like factor 10)54559.1030.0566No
33622"ING2 (inhibitor of growth family, member 2)"178621.2880.0101No
47057THBS1 (thrombospondin 1)183720.6620.0220No
580139ZNF703 (zinc finger protein 703)203318.4760.0252No
6657"BMPR1A (bone morphogenetic protein receptor, type IA)"216817.3780.0306No
758533SNX6 (sorting nexin 6)236715.4070.0315No
85300"PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1)"237115.3810.0420No
94087SMAD2 (SMAD family member 2)32089.9120.0076No
107040"TGFB1 (transforming growth factor, beta 1)"36658.104-0.0093No
113725JUN (jun oncogene)37007.938-0.0055No
122353FOS (v-fos FBJ murine osteosarcoma viral oncogene homolog)39386.979-0.0124No
13409"ARRB2 (arrestin, beta 2)"42056.074-0.0213No
144092SMAD7 (SMAD family member 7)43185.717-0.0229No
1590"ACVR1 (activin A receptor, type I)"43525.625-0.0206No
166868ADAM17 (ADAM metallopeptidase domain 17)44935.266-0.0238No
1723592LEMD3 (LEM domain containing 3)44955.262-0.0202No
186794STK11 (serine/threonine kinase 11)47864.524-0.0314No
1957154SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)48364.388-0.0308No
204090SMAD5 (SMAD family member 5)49824.072-0.0351No
215155PDGFB (platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog))53743.286-0.0522No
2251701NLK (nemo-like kinase)56992.752-0.0663No
231149CIDEA (cell death-inducing DFFA-like effector a)59792.399-0.0784No
242339"FNTA (farnesyltransferase, CAAX box, alpha)"64251.852-0.0991No
257321"UBE2D1 (ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast))"64801.793-0.1005No
262331FMOD (fibromodulin)65211.765-0.1013No
2764750SMURF2 (SMAD specific E3 ubiquitin protein ligase 2)68201.493-0.1150No
289719ADAMTSL2 (ADAMTS-like 2)69841.352-0.1221No
294053LTBP2 (latent transforming growth factor beta binding protein 2)70371.320-0.1237No
308425LTBP4 (latent transforming growth factor beta binding protein 4)71611.220-0.1290No
312200FBN1 (fibrillin 1)73641.088-0.1382No
32112744IL17F (interleukin 17F)77460.868-0.1564No
332122EVI1 (ecotropic viral integration site 1)77650.856-0.1567No
347044LEFTY2 (left-right determination factor 2)78170.826-0.1587No
357080NKX2-1 (NK2 homeobox 1)78290.819-0.1586No
3663976PRDM16 (PR domain containing 16)78950.786-0.1613No
372022ENG (endoglin (Osler-Rendu-Weber syndrome 1))84230.570-0.1870No
389392"TGFBRAP1 (transforming growth factor, beta receptor associated protein 1)"85770.521-0.1941No
397041TGFB1I1 (transforming growth factor beta 1 induced transcript 1)86590.493-0.1978No
404086SMAD1 (SMAD family member 1)87060.479-0.1997No
41163126EID2 (EP300 interacting inhibitor of differentiation 2)87810.451-0.2031No
422201FBN2 (fibrillin 2)95290.247-0.2398No
432488"FSHB (follicle stimulating hormone, beta polypeptide)"97250.201-0.2493No
443248HPGD (hydroxyprostaglandin dehydrogenase 15-(NAD))97910.184-0.2524No
454089SMAD4 (SMAD family member 4)10664-0.017-0.2955No
461278"COL1A2 (collagen, type I, alpha 2)"11598-0.234-0.3414No
4754829ASPN (asporin)11654-0.249-0.3440No
487042"TGFB2 (transforming growth factor, beta 2)"11675-0.254-0.3448No
497048"TGFBR2 (transforming growth factor, beta receptor II (70/80kDa))"12260-0.389-0.3734No
506664SOX11 (SRY (sex determining region Y)-box 11)12616-0.488-0.3906No
512662GDF10 (growth differentiation factor 10)12662-0.501-0.3924No
528287"USP9Y (ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila))"12913-0.580-0.4044No
531028"CDKN1C (cyclin-dependent kinase inhibitor 1C (p57, Kip2))"13428-0.754-0.4293No
5410637LEFTY1 (left-right determination factor 1)14022-1.005-0.4579No
558928FOXH1 (forkhead box H1)14288-1.128-0.4702No
561281"COL3A1 (collagen, type III, alpha 1)"14434-1.202-0.4765No
572661GDF9 (growth differentiation factor 9)14854-1.454-0.4962No
586498SKIL (SKI-like oncogene)14890-1.481-0.4969No
597049"TGFBR3 (transforming growth factor, beta receptor III)"14997-1.561-0.5011No
608200GDF5 (growth differentiation factor 5)15809-2.265-0.5396No
614435"CITED1 (Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1)"15894-2.354-0.5421No
62607BCL9 (B-cell CLL/lymphoma 9)16190-2.744-0.5547No
6356940DUSP22 (dual specificity phosphatase 22)16775-3.739-0.5810No
6494ACVRL1 (activin A receptor type II-like 1)16780-3.748-0.5786No
654052LTBP1 (latent transforming growth factor beta binding protein 1)17501-5.649-0.6103No
665494"PPM1A (protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform)"17598-6.003-0.6108No
675045FURIN (furin (paired basic amino acid cleaving enzyme))17734-6.604-0.6129No
684221MEN1 (multiple endocrine neoplasia I)17921-7.493-0.6169No
697046"TGFBR1 (transforming growth factor, beta receptor 1)"18051-8.147-0.6176Yes
707043"TGFB3 (transforming growth factor, beta 3)"18102-8.466-0.6142Yes
7151592TRIM33 (tripartite motif-containing 33)18150-8.757-0.6105Yes
729372"ZFYVE9 (zinc finger, FYVE domain containing 9)"18308-9.670-0.6115Yes
738754ADAM9 (ADAM metallopeptidase domain 9 (meltrin gamma))18549-11.504-0.6154Yes
744091SMAD6 (SMAD family member 6)18569-11.753-0.6082Yes
754088SMAD3 (SMAD family member 3)18573-11.772-0.6002Yes
768239"USP9X (ubiquitin specific peptidase 9, X-linked)"18719-13.272-0.5981Yes
775796"PTPRK (protein tyrosine phosphatase, receptor type, K)"18768-13.761-0.5910Yes
786497SKI (v-ski sarcoma viral oncogene homolog (avian))18818-14.221-0.5835Yes
791030"CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4))"18830-14.350-0.5741Yes
80283149BCL9L (B-cell CLL/lymphoma 9-like)19472-27.591-0.5866Yes
819518GDF15 (growth differentiation factor 15)19802-42.423-0.5734Yes
827323"UBE2D3 (ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast))"19877-49.242-0.5429Yes
8310755"GIPC1 (GIPC PDZ domain containing family, member 1)"19891-50.423-0.5086Yes
8428996HIPK2 (homeodomain interacting protein kinase 2)20050-69.317-0.4683Yes
8510370"CITED2 (Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2)"20070-71.972-0.4193Yes
863397"ID1 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein)"20316-310.355-0.2161Yes
8725805BAMBI (BMP and activin membrane-bound inhibitor homolog (Xenopus laevis))20317-312.0360.0004Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0007179   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0007179: Random ES distribution   
Gene set null distribution of ES for GO|GO:0007179