Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetKEGG|HSA04742
Enrichment Score (ES)-0.76147676
Normalized Enrichment Score (NES)-1.7053761
Nominal p-value0.0
FDR q-value0.12155658
FWER p-Value0.89
Table: GSEA Results Summary



Fig 1: Enrichment plot: KEGG|HSA04742   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
16337"SCNN1A (sodium channel, nonvoltage-gated 1 alpha)"42995.802-0.1973No
25613"PRKX (protein kinase, X-linked)"46224.924-0.2007No
35136"PDE1A (phosphodiesterase 1A, calmodulin-dependent)"64511.820-0.2862No
450838"TAS2R13 (taste receptor, type 2, member 13)"73451.100-0.3275No
5259296"TAS2R50 (taste receptor, type 2, member 50)"76660.902-0.3410No
6114ADCY8 (adenylate cyclase 8 (brain))77540.864-0.3431No
780834"TAS1R2 (taste receptor, type 1, member 2)"79460.762-0.3506No
850834"TAS2R1 (taste receptor, type 2, member 1)"79920.740-0.3509No
93710"ITPR3 (inositol 1,4,5-triphosphate receptor, type 3)"80250.723-0.3507No
10259286"TAS2R40 (taste receptor, type 2, member 40)"84770.551-0.3715No
115568"PRKACG (protein kinase, cAMP-dependent, catalytic, gamma)"85650.525-0.3745No
1250832"TAS2R4 (taste receptor, type 2, member 4)"89450.402-0.3922No
13259287"TAS2R41 (taste receptor, type 2, member 41)"91490.346-0.4013No
142785"GNG3 (guanine nucleotide binding protein (G protein), gamma 3)"93050.303-0.4082No
15196883ADCY4 (adenylate cyclase 4)98490.170-0.4345No
16259294"TAS2R48 (taste receptor, type 2, member 48)"99340.150-0.4383No
1750836"TAS2R8 (taste receptor, type 2, member 8)"102440.075-0.4533No
1850837"TAS2R7 (taste receptor, type 2, member 7)"10667-0.018-0.4741No
1950831"TAS2R3 (taste receptor, type 2, member 3)"11187-0.141-0.4993No
2050840"TAS2R14 (taste receptor, type 2, member 14)"11245-0.153-0.5017No
21346562"GNAT3 (guanine nucleotide binding protein, alpha transducing 3)"11473-0.208-0.5124No
2250835"TAS2R9 (taste receptor, type 2, member 9)"11490-0.211-0.5127No
233745"KCNB1 (potassium voltage-gated channel, Shab-related subfamily, member 1)"11571-0.228-0.5160No
2450839"TAS2R10 (taste receptor, type 2, member 10)"12926-0.584-0.5813No
25774"CACNA1B (calcium channel, voltage-dependent, N type, alpha 1B subunit)"13537-0.789-0.6094No
2654429"TAS2R5 (taste receptor, type 2, member 5)"13540-0.791-0.6075No
27259285"TAS2R39 (taste receptor, type 2, member 39)"13590-0.811-0.6078No
2850833"TAS2R16 (taste receptor, type 2, member 16)"14006-0.999-0.6258No
296340"SCNN1G (sodium channel, nonvoltage-gated 1, gamma)"14089-1.041-0.6272No
305726"TAS2R38 (taste receptor, type 2, member 38)"14164-1.072-0.6281No
316338"SCNN1B (sodium channel, nonvoltage-gated 1, beta)"14445-1.207-0.6389No
3240"ACCN1 (amiloride-sensitive cation channel 1, neuronal)"14585-1.287-0.6425No
3380835"TAS1R1 (taste receptor, type 1, member 1)"14683-1.348-0.6439No
3429850"TRPM5 (transient receptor potential cation channel, subfamily M, member 5)"15561-2.024-0.6820No
3551764"GNG13 (guanine nucleotide binding protein (G protein), gamma 13)"16012-2.512-0.6978No
365330"PLCB2 (phospholipase C, beta 2)"16712-3.624-0.7231No
37773"CACNA1A (calcium channel, voltage-dependent, P/Q type, alpha 1A subunit)"17205-4.752-0.7354No
382782"GNB1 (guanine nucleotide binding protein (G protein), beta polypeptide 1)"17381-5.227-0.7308No
392784"GNB3 (guanine nucleotide binding protein (G protein), beta polypeptide 3)"17419-5.344-0.7191No
405566"PRKACA (protein kinase, cAMP-dependent, catalytic, alpha)"18280-9.482-0.7375Yes
412914"GRM4 (glutamate receptor, metabotropic 4)"18451-10.801-0.7186Yes
42112ADCY6 (adenylate cyclase 6)18936-15.810-0.7025Yes
435567"PRKACB (protein kinase, cAMP-dependent, catalytic, beta)"19040-17.599-0.6630Yes
442778GNAS (GNAS complex locus)20315-287.2330.0005Yes
Table: GSEA details [plain text format]



Fig 2: KEGG|HSA04742   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KEGG|HSA04742: Random ES distribution   
Gene set null distribution of ES for KEGG|HSA04742