Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0051607
Enrichment Score (ES)-0.649058
Normalized Enrichment Score (NES)-1.5661181
Nominal p-value0.012861736
FDR q-value0.3214722
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0051607   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1664BNIP3 (BCL2/adenovirus E1B 19kDa interacting protein 3)22897.4040.0538No
28772FADD (Fas (TNFRSF6)-associated via death domain)80844.4950.0549No
3596BCL2 (B-cell CLL/lymphoma 2)176021.5050.0223No
41175"AP2S1 (adaptor-related protein complex 2, sigma 1 subunit)"177721.3430.0358No
5162"AP1B1 (adaptor-related protein complex 1, beta 1 subunit)"202018.5650.0362No
68905"AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)"224016.7450.0366No
76895TARBP2 (TAR (HIV-1) RNA binding protein 2)225116.6370.0472No
8163"AP2B1 (adaptor-related protein complex 2, beta 1 subunit)"251114.1970.0439No
9161"AP2A2 (adaptor-related protein complex 2, alpha 2 subunit)"254413.9210.0516No
104277MICB (MHC class I polypeptide-related sequence B)268812.9370.0532No
118907"AP1M1 (adaptor-related protein complex 1, mu 1 subunit)"314510.2050.0375No
12130340"AP1S3 (adaptor-related protein complex 1, sigma 3 subunit)"37747.6150.0115No
1351191HERC5 (hect domain and RLD 5)41406.303-0.0023No
142534"FYN (FYN oncogene related to SRC, FGR, YES)"42445.992-0.0034No
157187TRAF3 (TNF receptor-associated factor 3)43285.691-0.0037No
16255520ELMOD2 (ELMO/CED-12 domain containing 2)45145.198-0.0093No
171174"AP1S1 (adaptor-related protein complex 1, sigma 1 subunit)"46824.756-0.0144No
18160"AP2A1 (adaptor-related protein complex 2, alpha 1 subunit)"46984.725-0.0120No
1960489"APOBEC3G (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G)"58202.589-0.0656No
202150F2RL1 (coagulation factor II (thrombin) receptor-like 1)59232.465-0.0690No
21282618"IL29 (interleukin 29 (interferon, lambda 1))"67861.527-0.1105No
22149233IL23R (interleukin 23 receptor)72281.174-0.1315No
23340061TMEM173 (transmembrane protein 173)73611.090-0.1373No
2483737ITCH (itchy E3 ubiquitin protein ligase homolog (mouse))75900.949-0.1480No
253932LCK (lymphocyte-specific protein tyrosine kinase)86020.511-0.1975No
265551PRF1 (perforin 1 (pore forming protein))93140.302-0.2324No
273569"IL6 (interleukin 6 (interferon, beta 2))"97700.188-0.2548No
2854476RNF216 (ring finger protein 216)98320.174-0.2577No
29919CD247 (CD247 molecule)98650.167-0.2592No
3051284TLR7 (toll-like receptor 7)104920.016-0.2901No
311130LYST (lysosomal trafficking regulator)10863-0.062-0.3083No
325788"PTPRC (protein tyrosine phosphatase, receptor type, C)"11206-0.144-0.3251No
333593"IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))"11374-0.185-0.3332No
347098TLR3 (toll-like receptor 3)11911-0.304-0.3595No
35940CD28 (CD28 molecule)12034-0.333-0.3653No
36920CD4 (CD4 molecule)12457-0.446-0.3858No
3710060"ABCC9 (ATP-binding cassette, sub-family C (CFTR/MRP), member 9)"12798-0.543-0.4022No
38200315"APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A)"12811-0.548-0.4025No
3950489"CD207 (CD207 molecule, langerin)"13390-0.738-0.4305No
4051311TLR8 (toll-like receptor 8)13682-0.846-0.4443No
416041"RNASEL (ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent))"13797-0.896-0.4493No
42163702"IL28RA (interleukin 28 receptor, alpha (interferon, lambda receptor))"13920-0.961-0.4547No
431794DOCK2 (dedicator of cytokinesis 2)14135-1.064-0.4646No
44926CD8B (CD8b molecule)14383-1.176-0.4760No
459844ELMO1 (engulfment and cell motility 1)14392-1.178-0.4756No
467128"TNFAIP3 (tumor necrosis factor, alpha-induced protein 3)"14654-1.331-0.4876No
473456"IFNB1 (interferon, beta 1, fibroblast)"14732-1.384-0.4905No
483594"IL12RB1 (interleukin 12 receptor, beta 1)"15945-2.429-0.5487No
493055HCK (hemopoietic cell kinase)16018-2.517-0.5506No
5084166"NLRC5 (NLR family, CARD domain containing 5)"16156-2.702-0.5555No
5181844TRIM56 (tripartite motif-containing 56)16172-2.721-0.5545No
5291543RSAD2 (radical S-adenosyl methionine domain containing 2)16978-4.199-0.5914No
53200316"APOBEC3F (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F)"17527-5.737-0.6146No
5410053"AP1M2 (adaptor-related protein complex 1, mu 2 subunit)"17870-7.186-0.6267No
55665BNIP3L (BCL2/adenovirus E1B 19kDa interacting protein 3-like)18121-8.583-0.6333No
565970RELA (v-rel reticuloendotheliosis viral oncogene homolog A (avian))18184-8.954-0.6304No
5725939SAMHD1 (SAM domain and HD domain 1)18307-9.649-0.6300No
585371PML (promyelocytic leukemia)18450-10.797-0.6298No
5951606"ATP6V1H (ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H)"18782-13.854-0.6369No
6051561"IL23A (interleukin 23, alpha subunit p19)"19029-17.353-0.6375Yes
61684BST2 (bone marrow stromal cell antigen 2)19237-21.251-0.6335Yes
6223586DDX58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58)19385-25.182-0.6239Yes
63375ARF1 (ADP-ribosylation factor 1)19469-27.515-0.6097Yes
6455690PACS1 (phosphofurin acidic cluster sorting protein 1)19567-30.534-0.5941Yes
655879"RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))"19612-32.214-0.5747Yes
6657506VISA (virus-induced signaling adapter)19622-32.677-0.5534Yes
675062PAK2 (p21 protein (Cdc42/Rac)-activated kinase 2)19777-40.918-0.5336Yes
68164"AP1G1 (adaptor-related protein complex 1, gamma 1 subunit)"19805-42.696-0.5065Yes
691173"AP2M1 (adaptor-related protein complex 2, mu 1 subunit)"19821-43.932-0.4779Yes
704938"OAS1 (2',5'-oligoadenylate synthetase 1, 40/46kDa)"19903-51.434-0.4475Yes
715094PCBP2 (poly(rC) binding protein 2)20076-73.183-0.4072Yes
724940"OAS3 (2'-5'-oligoadenylate synthetase 3, 100kDa)"20125-86.843-0.3515Yes
735359PLSCR1 (phospholipid scramblase 1)20126-86.908-0.2935Yes
74567B2M (beta-2-microglobulin)20305-220.982-0.1548Yes
753434IFIT1 (interferon-induced protein with tetratricopeptide repeats 1)20306-233.1720.0009Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0051607   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0051607: Random ES distribution   
Gene set null distribution of ES for GO|GO:0051607