Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0005774
Enrichment Score (ES)-0.6616578
Normalized Enrichment Score (NES)-1.5795513
Nominal p-value0.0065789474
FDR q-value0.3008119
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0005774   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
154978C2orf18 (chromosome 2 open reading frame 18)149625.436-0.0531No
26845VAMP7 (vesicle-associated membrane protein 7)170222.357-0.0449No
3162"AP1B1 (adaptor-related protein complex 1, beta 1 subunit)"202018.565-0.0454No
4121260"SLC15A4 (solute carrier family 15, member 4)"215217.461-0.0376No
58905"AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)"224016.745-0.0282No
69296"ATP6V1F (ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F)"228816.117-0.0174No
710058"ABCB6 (ATP-binding cassette, sub-family B (MDR/TAP), member 6)"231615.892-0.0058No
83123"HLA-DRB1 (major histocompatibility complex, class II, DR beta 1)"257913.655-0.0075No
951361HOOK1 (hook homolog 1 (Drosophila))275712.442-0.0061No
108907"AP1M1 (adaptor-related protein complex 1, mu 1 subunit)"314510.205-0.0169No
1153373TPCN1 (two pore segment channel 1)34718.854-0.0257No
12284129"SLC26A11 (solute carrier family 26, member 11)"37117.893-0.0310No
13219931TPCN2 (two pore segment channel 2)37477.716-0.0265No
14130340"AP1S3 (adaptor-related protein complex 1, sigma 3 subunit)"37747.615-0.0215No
151203"CLN5 (ceroid-lipofuscinosis, neuronal 5)"41026.430-0.0324No
1657617VPS18 (vacuolar protein sorting 18 homolog (S. cerevisiae))43495.628-0.0400No
173126"HLA-DRB4 (major histocompatibility complex, class II, DR beta 4)"43715.560-0.0365No
1823457"ABCB9 (ATP-binding cassette, sub-family B (MDR/TAP), member 9)"45535.110-0.0412No
191174"AP1S1 (adaptor-related protein complex 1, sigma 1 subunit)"46824.756-0.0437No
20408"ARRB1 (arrestin, beta 1)"49284.173-0.0523No
2127072VPS41 (vacuolar protein sorting 41 homolog (S. cerevisiae))53233.359-0.0691No
223127"HLA-DRB5 (major histocompatibility complex, class II, DR beta 5)"60782.255-0.1044No
2384376HOOK3 (hook homolog 3 (Drosophila))64161.860-0.1195No
2463894C14orf133 (chromosome 14 open reading frame 133)73241.116-0.1634No
25245972"ATP6V0D2 (ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2)"75890.949-0.1757No
264948OCA2 (oculocutaneous albinism II)80530.708-0.1979No
2751296"SLC15A3 (solute carrier family 15, member 3)"93220.299-0.2603No
28358AQP1 (aquaporin 1 (Colton blood group))102260.078-0.3048No
2955016MARCH1 (membrane-associated ring finger (C3HC4) 1)10672-0.020-0.3268No
30525"ATP6V1B1 (ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1)"11564-0.227-0.3705No
314935GPR143 (G protein-coupled receptor 143)12434-0.440-0.4131No
329525VPS4B (vacuolar protein sorting 4 homolog B (S. cerevisiae))13180-0.662-0.4493No
334647MYO7A (myosin VIIA)13917-0.960-0.4849No
349725TMEM63A (transmembrane protein 63A)14038-1.014-0.4900No
3564601VPS16 (vacuolar protein sorting 16 homolog (S. cerevisiae))15648-2.096-0.5677No
3665082VPS33A (vacuolar protein sorting 33 homolog A (S. cerevisiae))15667-2.113-0.5668No
37138050HGSNAT (heparan-alpha-glucosaminide N-acetyltransferase)16006-2.509-0.5815No
381497"CTNS (cystinosis, nephropathic)"16959-4.140-0.6251No
3923339VPS39 (vacuolar protein sorting 39 homolog (S. cerevisiae))17133-4.592-0.6299No
4011342RNF13 (ring finger protein 13)17465-5.513-0.6417No
4110053"AP1M2 (adaptor-related protein complex 1, mu 2 subunit)"17870-7.186-0.6558Yes
4226276VPS33B (vacuolar protein sorting 33 homolog B (yeast))17902-7.377-0.6513Yes
4355062"WIPI1 (WD repeat domain, phosphoinositide interacting 1)"17994-7.878-0.6494Yes
443122"HLA-DRA (major histocompatibility complex, class II, DR alpha)"17997-7.888-0.6430Yes
455664PSEN2 (presenilin 2 (Alzheimer disease 4))18005-7.937-0.6369Yes
464891"SLC11A2 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2)"18016-7.985-0.6308Yes
4711337GABARAP (GABA(A) receptor-associated protein)18240-9.216-0.6343Yes
48373TRIM23 (tripartite motif-containing 23)18300-9.614-0.6294Yes
4926503"SLC17A5 (solute carrier family 17 (anion/sugar transporter), member 5)"18347-9.886-0.6236Yes
5083547RILP (Rab interacting lysosomal protein)18383-10.168-0.6170Yes
512647"BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1)"18593-11.970-0.6175Yes
5250617"ATP6V0A4 (ATPase, H+ transporting, lysosomal V0 subunit a4)"18596-11.995-0.6079Yes
532629"GBA (glucosidase, beta; acid (includes glucosylceramidase))"18623-12.262-0.5991Yes
5451606"ATP6V1H (ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H)"18782-13.854-0.5956Yes
5555315"SLC29A3 (solute carrier family 29 (nucleoside transporters), member 3)"19100-18.778-0.5959Yes
5629911HOOK2 (hook homolog 2 (Drosophila))19137-19.542-0.5817Yes
5755823VPS11 (vacuolar protein sorting 11 homolog (S. cerevisiae))19149-19.713-0.5662Yes
589114"ATP6V0D1 (ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1)"19347-24.177-0.5562Yes
5951092"SIDT2 (SID1 transmembrane family, member 2)"19507-28.505-0.5407Yes
605663PSEN1 (presenilin 1)19728-38.379-0.5202Yes
61164"AP1G1 (adaptor-related protein complex 1, gamma 1 subunit)"19805-42.696-0.4891Yes
6264400AKTIP (AKT interacting protein)19904-51.459-0.4519Yes
6326100"WIPI2 (WD repeat domain, phosphoinositide interacting 2)"19912-52.575-0.4093Yes
641201"CLN3 (ceroid-lipofuscinosis, neuronal 3)"19985-61.160-0.3629Yes
653920LAMP2 (lysosomal-associated membrane protein 2)20061-70.710-0.3089Yes
66950"SCARB2 (scavenger receptor class B, member 2)"20115-83.041-0.2437Yes
6751382"ATP6V1D (ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D)"20158-96.933-0.1666Yes
6811345GABARAPL2 (GABA(A) receptor-associated protein-like 2)20300-214.0170.0012Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0005774   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0005774: Random ES distribution   
Gene set null distribution of ES for GO|GO:0005774