Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0050688
Enrichment Score (ES)-0.7258303
Normalized Enrichment Score (NES)-1.6519476
Nominal p-value0.003012048
FDR q-value0.2213241
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0050688   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
11175"AP2S1 (adaptor-related protein complex 2, sigma 1 subunit)"177721.343-0.0671No
2162"AP1B1 (adaptor-related protein complex 1, beta 1 subunit)"202018.565-0.0612No
38905"AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)"224016.745-0.0559No
46895TARBP2 (TAR (HIV-1) RNA binding protein 2)225116.637-0.0405No
5163"AP2B1 (adaptor-related protein complex 2, beta 1 subunit)"251114.197-0.0396No
6161"AP2A2 (adaptor-related protein complex 2, alpha 2 subunit)"254413.921-0.0278No
74277MICB (MHC class I polypeptide-related sequence B)268812.937-0.0224No
88907"AP1M1 (adaptor-related protein complex 1, mu 1 subunit)"314510.205-0.0351No
9130340"AP1S3 (adaptor-related protein complex 1, sigma 3 subunit)"37747.615-0.0588No
1051191HERC5 (hect domain and RLD 5)41406.303-0.0707No
112534"FYN (FYN oncogene related to SRC, FGR, YES)"42445.992-0.0700No
127187TRAF3 (TNF receptor-associated factor 3)43285.691-0.0687No
13255520ELMOD2 (ELMO/CED-12 domain containing 2)45145.198-0.0728No
141174"AP1S1 (adaptor-related protein complex 1, sigma 1 subunit)"46824.756-0.0765No
15160"AP2A1 (adaptor-related protein complex 2, alpha 1 subunit)"46984.725-0.0727No
1660489"APOBEC3G (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G)"58202.589-0.1255No
17149233IL23R (interleukin 23 receptor)72281.174-0.1937No
18340061TMEM173 (transmembrane protein 173)73611.090-0.1992No
1983737ITCH (itchy E3 ubiquitin protein ligase homolog (mouse))75900.949-0.2095No
203932LCK (lymphocyte-specific protein tyrosine kinase)86020.511-0.2589No
2154476RNF216 (ring finger protein 216)98320.174-0.3193No
22919CD247 (CD247 molecule)98650.167-0.3207No
233593"IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))"11374-0.185-0.3949No
24940CD28 (CD28 molecule)12034-0.333-0.4271No
25920CD4 (CD4 molecule)12457-0.446-0.4475No
26163702"IL28RA (interleukin 28 receptor, alpha (interferon, lambda receptor))"13920-0.961-0.5187No
271794DOCK2 (dedicator of cytokinesis 2)14135-1.064-0.5282No
28926CD8B (CD8b molecule)14383-1.176-0.5392No
299844ELMO1 (engulfment and cell motility 1)14392-1.178-0.5385No
307128"TNFAIP3 (tumor necrosis factor, alpha-induced protein 3)"14654-1.331-0.5501No
313594"IL12RB1 (interleukin 12 receptor, beta 1)"15945-2.429-0.6114No
323055HCK (hemopoietic cell kinase)16018-2.517-0.6125No
33200316"APOBEC3F (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F)"17527-5.737-0.6814No
3410053"AP1M2 (adaptor-related protein complex 1, mu 2 subunit)"17870-7.186-0.6913No
355371PML (promyelocytic leukemia)18450-10.797-0.7095No
3651606"ATP6V1H (ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H)"18782-13.854-0.7125Yes
3751561"IL23A (interleukin 23, alpha subunit p19)"19029-17.353-0.7080Yes
3823586DDX58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58)19385-25.182-0.7013Yes
39375ARF1 (ADP-ribosylation factor 1)19469-27.515-0.6790Yes
4055690PACS1 (phosphofurin acidic cluster sorting protein 1)19567-30.534-0.6544Yes
415879"RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))"19612-32.214-0.6256Yes
4257506VISA (virus-induced signaling adapter)19622-32.677-0.5947Yes
435062PAK2 (p21 protein (Cdc42/Rac)-activated kinase 2)19777-40.918-0.5630Yes
44164"AP1G1 (adaptor-related protein complex 1, gamma 1 subunit)"19805-42.696-0.5233Yes
451173"AP2M1 (adaptor-related protein complex 2, mu 1 subunit)"19821-43.932-0.4818Yes
465094PCBP2 (poly(rC) binding protein 2)20076-73.183-0.4241Yes
47567B2M (beta-2-microglobulin)20305-220.982-0.2230Yes
483434IFIT1 (interferon-induced protein with tetratricopeptide repeats 1)20306-233.1720.0009Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0050688   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0050688: Random ES distribution   
Gene set null distribution of ES for GO|GO:0050688