Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | GO|GO:0045165 |
Enrichment Score (ES) | -0.7014592 |
Normalized Enrichment Score (NES) | -1.7246374 |
Nominal p-value | 0.0 |
FDR q-value | 0.11320829 |
FWER p-Value | 0.774 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 1499 | "CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa)" | 480 | 63.932 | 0.0260 | No | ||
2 | 9314 | KLF4 (Kruppel-like factor 4 (gut)) | 831 | 43.467 | 0.0425 | No | ||
3 | 2296 | FOXC1 (forkhead box C1) | 2238 | 16.764 | -0.0139 | No | ||
4 | 429 | ASCL1 (achaete-scute complex homolog 1 (Drosophila)) | 2462 | 14.694 | -0.0135 | No | ||
5 | 7855 | FZD5 (frizzled homolog 5 (Drosophila)) | 2771 | 12.344 | -0.0191 | No | ||
6 | 3475 | IFRD1 (interferon-related developmental regulator 1) | 2863 | 11.892 | -0.0143 | No | ||
7 | 4087 | SMAD2 (SMAD family member 2) | 3208 | 9.912 | -0.0236 | No | ||
8 | 8324 | FZD7 (frizzled homolog 7 (Drosophila)) | 3360 | 9.324 | -0.0238 | No | ||
9 | 7479 | "WNT8B (wingless-type MMTV integration site family, member 8B)" | 4718 | 4.675 | -0.0872 | No | ||
10 | 3207 | HOXA11 (homeobox A11) | 4720 | 4.672 | -0.0836 | No | ||
11 | 6662 | SOX9 (SRY (sex determining region Y)-box 9) | 5204 | 3.599 | -0.1047 | No | ||
12 | 8312 | AXIN1 (axin 1) | 5253 | 3.490 | -0.1044 | No | ||
13 | 2623 | GATA1 (GATA binding protein 1 (globin transcription factor 1)) | 5648 | 2.850 | -0.1216 | No | ||
14 | 2263 | FGFR2 (fibroblast growth factor receptor 2) | 6001 | 2.374 | -0.1371 | No | ||
15 | 6886 | TAL1 (T-cell acute lymphocytic leukemia 1) | 6165 | 2.156 | -0.1435 | No | ||
16 | 7473 | "WNT3 (wingless-type MMTV integration site family, member 3)" | 6468 | 1.804 | -0.1570 | No | ||
17 | 4656 | MYOG (myogenin (myogenic factor 4)) | 6837 | 1.474 | -0.1741 | No | ||
18 | 7478 | "WNT8A (wingless-type MMTV integration site family, member 8A)" | 7019 | 1.336 | -0.1820 | No | ||
19 | 149233 | IL23R (interleukin 23 receptor) | 7228 | 1.174 | -0.1913 | No | ||
20 | 388585 | HES5 (hairy and enhancer of split 5 (Drosophila)) | 7365 | 1.087 | -0.1972 | No | ||
21 | 57453 | DSCAML1 (Down syndrome cell adhesion molecule like 1) | 7445 | 1.037 | -0.2003 | No | ||
22 | 4618 | MYF6 (myogenic factor 6 (herculin)) | 7767 | 0.856 | -0.2155 | No | ||
23 | 6657 | SOX2 (SRY (sex determining region Y)-box 2) | 8020 | 0.724 | -0.2274 | No | ||
24 | 7482 | "WNT2B (wingless-type MMTV integration site family, member 2B)" | 8184 | 0.658 | -0.2349 | No | ||
25 | 30812 | SOX8 (SRY (sex determining region Y)-box 8) | 8253 | 0.631 | -0.2378 | No | ||
26 | 7490 | WT1 (Wilms tumor 1) | 8559 | 0.526 | -0.2525 | No | ||
27 | 6299 | SALL1 (sal-like 1 (Drosophila)) | 8649 | 0.497 | -0.2565 | No | ||
28 | 2299 | FOXI1 (forkhead box I1) | 9168 | 0.342 | -0.2818 | No | ||
29 | 2139 | EYA2 (eyes absent homolog 2 (Drosophila)) | 9300 | 0.305 | -0.2880 | No | ||
30 | 6997 | TDGF1 (teratocarcinoma-derived growth factor 1) | 9475 | 0.260 | -0.2964 | No | ||
31 | 5076 | PAX2 (paired box 2) | 9603 | 0.228 | -0.3025 | No | ||
32 | 6495 | SIX1 (SIX homeobox 1) | 9891 | 0.159 | -0.3166 | No | ||
33 | 4617 | MYF5 (myogenic factor 5) | 9908 | 0.156 | -0.3172 | No | ||
34 | 79923 | NANOG (Nanog homeobox) | 9923 | 0.151 | -0.3178 | No | ||
35 | 3670 | ISL1 (ISL LIM homeobox 1) | 10817 | -0.051 | -0.3619 | No | ||
36 | 64321 | SOX17 (SRY (sex determining region Y)-box 17) | 11243 | -0.153 | -0.3828 | No | ||
37 | 2303 | "FOXC2 (forkhead box C2 (MFH-1, mesenchyme forkhead 1))" | 11316 | -0.168 | -0.3862 | No | ||
38 | 3171 | FOXA3 (forkhead box A3) | 11323 | -0.170 | -0.3864 | No | ||
39 | 3593 | "IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))" | 11374 | -0.185 | -0.3887 | No | ||
40 | 2307 | FOXS1 (forkhead box S1) | 11488 | -0.211 | -0.3941 | No | ||
41 | 4654 | MYOD1 (myogenic differentiation 1) | 11595 | -0.233 | -0.3992 | No | ||
42 | 28514 | DLL1 (delta-like 1 (Drosophila)) | 11811 | -0.283 | -0.4096 | No | ||
43 | 1848 | DUSP6 (dual specificity phosphatase 6) | 11822 | -0.286 | -0.4098 | No | ||
44 | 7471 | "WNT1 (wingless-type MMTV integration site family, member 1)" | 12102 | -0.347 | -0.4233 | No | ||
45 | 11281 | POU6F2 (POU class 6 homeobox 2) | 12655 | -0.500 | -0.4502 | No | ||
46 | 7472 | WNT2 (wingless-type MMTV integration site family member 2) | 12752 | -0.529 | -0.4546 | No | ||
47 | 5468 | PPARG (peroxisome proliferator-activated receptor gamma) | 12768 | -0.534 | -0.4549 | No | ||
48 | 56603 | "CYP26B1 (cytochrome P450, family 26, subfamily B, polypeptide 1)" | 12892 | -0.573 | -0.4605 | No | ||
49 | 5457 | POU4F1 (POU class 4 homeobox 1) | 12937 | -0.587 | -0.4622 | No | ||
50 | 2247 | FGF2 (fibroblast growth factor 2 (basic)) | 13137 | -0.649 | -0.4716 | No | ||
51 | 5460 | POU5F1 (POU class 5 homeobox 1) | 13341 | -0.718 | -0.4810 | No | ||
52 | 3170 | FOXA2 (forkhead box A2) | 13351 | -0.723 | -0.4809 | No | ||
53 | 4855 | NOTCH4 (Notch homolog 4 (Drosophila)) | 13834 | -0.914 | -0.5040 | No | ||
54 | 6469 | SHH (sonic hedgehog homolog (Drosophila)) | 14133 | -1.064 | -0.5179 | No | ||
55 | 4909 | NTF4 (neurotrophin 4) | 14196 | -1.086 | -0.5201 | No | ||
56 | 650 | BMP2 (bone morphogenetic protein 2) | 14423 | -1.193 | -0.5304 | No | ||
57 | 4208 | MEF2C (myocyte enhancer factor 2C) | 14451 | -1.211 | -0.5307 | No | ||
58 | 2736 | GLI2 (GLI-Kruppel family member GLI2) | 14561 | -1.273 | -0.5351 | No | ||
59 | 89870 | TRIM15 (tripartite motif-containing 15) | 14775 | -1.409 | -0.5446 | No | ||
60 | 5080 | PAX6 (paired box 6) | 14826 | -1.435 | -0.5459 | No | ||
61 | 6608 | SMO (smoothened homolog (Drosophila)) | 14976 | -1.544 | -0.5521 | No | ||
62 | 5629 | PROX1 (prospero homeobox 1) | 15044 | -1.592 | -0.5542 | No | ||
63 | 3714 | JAG2 (jagged 2) | 15118 | -1.652 | -0.5565 | No | ||
64 | 3594 | "IL12RB1 (interleukin 12 receptor, beta 1)" | 15945 | -2.429 | -0.5954 | No | ||
65 | 6899 | TBX1 (T-box 1) | 16186 | -2.739 | -0.6051 | No | ||
66 | 182 | JAG1 (jagged 1 (Alagille syndrome)) | 16647 | -3.487 | -0.6251 | No | ||
67 | 6666 | SOX12 (SRY (sex determining region Y)-box 12) | 17154 | -4.635 | -0.6465 | No | ||
68 | 55897 | MESP1 (mesoderm posterior 1 homolog (mouse)) | 17684 | -6.362 | -0.6677 | No | ||
69 | 7046 | "TGFBR1 (transforming growth factor, beta receptor 1)" | 18051 | -8.147 | -0.6795 | No | ||
70 | 652 | BMP4 (bone morphogenetic protein 4) | 18378 | -10.143 | -0.6877 | No | ||
71 | 161882 | "ZFPM1 (zinc finger protein, multitype 1)" | 18444 | -10.759 | -0.6825 | No | ||
72 | 2624 | GATA2 (GATA binding protein 2) | 18660 | -12.664 | -0.6833 | No | ||
73 | 51561 | "IL23A (interleukin 23, alpha subunit p19)" | 19029 | -17.353 | -0.6880 | Yes | ||
74 | 2034 | EPAS1 (endothelial PAS domain protein 1) | 19065 | -18.219 | -0.6755 | Yes | ||
75 | 4170 | MCL1 (myeloid cell leukemia sequence 1 (BCL2-related)) | 19101 | -18.831 | -0.6626 | Yes | ||
76 | 6929 | TCF3 (transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)) | 19423 | -26.298 | -0.6580 | Yes | ||
77 | 7026 | "NR2F2 (nuclear receptor subfamily 2, group F, member 2)" | 19595 | -31.444 | -0.6420 | Yes | ||
78 | 6934 | "TCF7L2 (transcription factor 7-like 2 (T-cell specific, HMG-box))" | 19726 | -38.340 | -0.6186 | Yes | ||
79 | 3728 | JUP (junction plakoglobin) | 19987 | -61.273 | -0.5838 | Yes | ||
80 | 4853 | NOTCH2 (Notch homolog 2 (Drosophila)) | 20121 | -85.023 | -0.5242 | Yes | ||
81 | 3398 | "ID2 (inhibitor of DNA binding 2, dominant negative helix-loop-helix protein)" | 20185 | -106.279 | -0.4446 | Yes | ||
82 | 3169 | FOXA1 (forkhead box A1) | 20189 | -110.661 | -0.3587 | Yes | ||
83 | 22943 | DKK1 (dickkopf homolog 1 (Xenopus laevis)) | 20301 | -214.170 | -0.1976 | Yes | ||
84 | 2625 | GATA3 (GATA binding protein 3) | 20312 | -255.499 | 0.0006 | Yes |