Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetREACTOME|REACT_19183.1
Enrichment Score (ES)-0.8218738
Normalized Enrichment Score (NES)-1.6666436
Nominal p-value0.0051020407
FDR q-value0.17908883
FWER p-Value0.994
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME|REACT_19183.1   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
17525YES1 (v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1)198718.910-0.0647No
22534"FYN (FYN oncogene related to SRC, FGR, YES)"42445.992-0.1653No
3208AKT2 (v-akt murine thymoma viral oncogene homolog 2)48794.290-0.1890No
41326MAP3K8 (mitogen-activated protein kinase kinase kinase 8)50723.886-0.1917No
52475FRAP1 (FK506 binding protein 12-rapamycin associated protein 1)51353.745-0.1882No
6117145THEM4 (thioesterase superfamily member 4)51633.689-0.1830No
75058PAK1 (p21 protein (Cdc42/Rac)-activated kinase 1)76460.920-0.3037No
83932LCK (lymphocyte-specific protein tyrosine kinase)86020.511-0.3498No
9942CD86 (CD86 molecule)10585-0.000-0.4475No
10940CD28 (CD28 molecule)12034-0.333-0.5182No
11941CD80 (CD80 molecule)13279-0.692-0.5783No
129020MAP3K14 (mitogen-activated protein kinase kinase kinase 14)14010-1.000-0.6125No
137409VAV1 (vav 1 guanine nucleotide exchange factor)14093-1.044-0.6147No
1457761TRIB3 (tribbles homolog 3 (Drosophila))15347-1.824-0.6732No
15253260RICTOR (rapamycin-insensitive companion of mTOR)16150-2.699-0.7080No
169402GRAP2 (GRB2-related adaptor protein 2)16323-2.949-0.7113No
1764223GBL (G protein beta subunit-like)17731-6.592-0.7691No
185290"PIK3CA (phosphoinositide-3-kinase, catalytic, alpha polypeptide)"17764-6.773-0.7587No
194067LYN (v-yes-1 Yamaguchi sarcoma viral related oncogene homolog)18419-10.518-0.7725No
205295"PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1 (alpha))"19422-26.295-0.7757Yes
21207AKT1 (v-akt murine thymoma viral oncogene homolog 1)19588-31.123-0.7293Yes
225879"RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))"19612-32.214-0.6739Yes
235062PAK2 (p21 protein (Cdc42/Rac)-activated kinase 2)19777-40.918-0.6102Yes
245170PDPK1 (3-phosphoinositide dependent protein kinase-1)19867-47.955-0.5304Yes
255296"PIK3R2 (phosphoinositide-3-kinase, regulatory subunit 2 (beta))"19918-53.218-0.4395Yes
26998"CDC42 (cell division cycle 42 (GTP binding protein, 25kDa))"20112-82.496-0.3043Yes
278503"PIK3R3 (phosphoinositide-3-kinase, regulatory subunit 3 (gamma))"20275-179.3720.0025Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME|REACT_19183.1   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME|REACT_19183.1: Random ES distribution   
Gene set null distribution of ES for REACTOME|REACT_19183.1