Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos
Phenotype | Phenotype.cls#treated_versus_cont_repos
Upregulated in class | cont
GeneSet | REACTOME|REACT_19238.1
Enrichment Score (ES) | -0.90751505
Normalized Enrichment Score (NES) | -1.5742238
Nominal p-value | 0.0125
FDR q-value | 0.3037612
FWER p-Value | 1.0
Table: GSEA Results Summary

Fig 1: Enrichment plot: REACTOME|REACT_19238.1
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT
1 | 2534 | "FYN (FYN oncogene related to SRC, FGR, YES)" |  |  | 4244 | 5.992 | -0.1726 | No
2 | 5058 | PAK1 (p21 protein (Cdc42/Rac)-activated kinase 1) |  |  | 7646 | 0.920 | -0.3344 | No
3 | 3932 | LCK (lymphocyte-specific protein tyrosine kinase) |  |  | 8602 | 0.511 | -0.3784 | No
4 | 942 | CD86 (CD86 molecule) |  |  | 10585 | -0.000 | -0.4759 | No
5 | 940 | CD28 (CD28 molecule) |  |  | 12034 | -0.333 | -0.5452 | No
6 | 941 | CD80 (CD80 molecule) |  |  | 13279 | -0.692 | -0.6022 | No
7 | 7409 | VAV1 (vav 1 guanine nucleotide exchange factor) |  |  | 14093 | -1.044 | -0.6359 | No
8 | 5879 | "RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))" |  |  | 19612 | -32.214 | -0.7124 | Yes
9 | 5062 | PAK2 (p21 protein (Cdc42/Rac)-activated kinase 2) |  |  | 19777 | -40.918 | -0.4727 | Yes
10 | 998 | "CDC42 (cell division cycle 42 (GTP binding protein, 25kDa))" |  |  | 20112 | -82.496 | 0.0105 | Yes
Table: GSEA details [plain text format]

Fig 2: REACTOME|REACT_19238.1
Blue-Pink O' Gram in the Space of the Analyzed GeneSet
Fig 3: REACTOME|REACT_19238.1: Random ES distribution
Gene set null distribution of ES for REACTOME|REACT_19238.1