Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetKEGG|HSA04961
Enrichment Score (ES)-0.7122107
Normalized Enrichment Score (NES)-1.6238494
Nominal p-value0.014705882
FDR q-value0.2571335
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: KEGG|HSA04961   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1483"ATP1B3 (ATPase, Na+/K+ transporting, beta 3 polypeptide)"29586.2720.0487No
21175"AP2S1 (adaptor-related protein complex 2, sigma 1 subunit)"177721.343-0.0087No
3115ADCY9 (adenylate cyclase 9)183120.7590.0040No
4476"ATP1A1 (ATPase, Na+/K+ transporting, alpha 1 polypeptide)"199518.7910.0097No
51212"CLTB (clathrin, light chain (Lcb))"216117.4230.0143No
6163"AP2B1 (adaptor-related protein complex 2, beta 1 subunit)"251114.1970.0075No
7161"AP2A2 (adaptor-related protein complex 2, alpha 2 subunit)"254413.9210.0162No
810059DNM1L (dynamin 1-like)259113.5330.0238No
9624BDKRB2 (bradykinin receptor B2)34868.794-0.0138No
101785DNM2 (dynamin 2)43195.715-0.0507No
115613"PRKX (protein kinase, X-linked)"46224.924-0.0619No
12160"AP2A1 (adaptor-related protein complex 2, alpha 1 subunit)"46984.725-0.0622No
135331"PLCB3 (phospholipase C, beta 3 (phosphatidylinositol-specific))"54173.204-0.0952No
1456302"TRPV5 (transient receptor potential cation channel, subfamily V, member 5)"56182.890-0.1030No
155582"PRKCG (protein kinase C, gamma)"62392.077-0.1320No
166546"SLC8A1 (solute carrier family 8 (sodium/calcium exchanger), member 1)"62632.049-0.1317No
175578"PRKCA (protein kinase C, alpha)"68271.483-0.1583No
185579"PRKCB (protein kinase C, beta)"70211.335-0.1669No
191759DNM1 (dynamin 1)72821.149-0.1789No
20482"ATP1B2 (ATPase, Na+/K+ transporting, beta 2 polypeptide)"73191.119-0.1798No
21480"ATP1A4 (ATPase, Na+/K+ transporting, alpha 4 polypeptide)"84060.576-0.2329No
225568"PRKACG (protein kinase, cAMP-dependent, catalytic, gamma)"85650.525-0.2404No
238218"CLTCL1 (clathrin, heavy chain-like 1)"101990.084-0.3208No
2423439"ATP1B4 (ATPase, (Na+)/K+ transporting, beta 4 polypeptide)"10727-0.031-0.3468No
25477"ATP1A2 (ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide)"11365-0.182-0.3781No
265745PTHR1 (parathyroid hormone receptor 1)11734-0.266-0.3960No
27793"CALB1 (calbindin 1, 28kDa)"12833-0.556-0.4498No
2826052DNM3 (dynamin 3)14081-1.038-0.5105No
299365KL (klotho)14228-1.098-0.5169No
30478"ATP1A3 (ATPase, Na+/K+ transporting, alpha 3 polypeptide)"14604-1.298-0.5344No
31486FXYD2 (FXYD domain containing ion transport regulator 2)15822-2.279-0.5928No
323817KLK2 (kallikrein-related peptidase 2)16268-2.852-0.6126No
335330"PLCB2 (phospholipase C, beta 2)"16712-3.624-0.6318No
343816KLK1 (kallikrein 1)16848-3.864-0.6357No
357421"VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor)"17509-5.685-0.6640No
365332"PLCB4 (phospholipase C, beta 4)"18080-8.342-0.6860No
375566"PRKACA (protein kinase, cAMP-dependent, catalytic, alpha)"18280-9.482-0.6889No
38490"ATP2B1 (ATPase, Ca++ transporting, plasma membrane 1)"18616-12.183-0.6965No
39112ADCY6 (adenylate cyclase 6)18936-15.810-0.7006Yes
405567"PRKACB (protein kinase, cAMP-dependent, catalytic, beta)"19040-17.599-0.6928Yes
4123236"PLCB1 (phospholipase C, beta 1 (phosphoinositide-specific))"19199-20.539-0.6855Yes
422776"GNAQ (guanine nucleotide binding protein (G protein), q polypeptide)"19223-20.899-0.6713Yes
431173"AP2M1 (adaptor-related protein complex 2, mu 1 subunit)"19821-43.932-0.6685Yes
441211"CLTA (clathrin, light chain (Lca))"19830-44.680-0.6362Yes
458766"RAB11A (RAB11A, member RAS oncogene family)"20090-75.961-0.5932Yes
461213"CLTC (clathrin, heavy chain (Hc))"20153-94.190-0.5272Yes
47481"ATP1B1 (ATPase, Na+/K+ transporting, beta 1 polypeptide)"20220-126.497-0.4377Yes
482778GNAS (GNAS complex locus)20315-287.233-0.2317Yes
492099ESR1 (estrogen receptor 1)20319-316.4700.0003Yes
Table: GSEA details [plain text format]



Fig 2: KEGG|HSA04961   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KEGG|HSA04961: Random ES distribution   
Gene set null distribution of ES for KEGG|HSA04961