Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetREACTOME|REACT_25162.1
Enrichment Score (ES)-0.8207189
Normalized Enrichment Score (NES)-1.9450018
Nominal p-value0.0
FDR q-value0.0024581559
FWER p-Value0.0020
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME|REACT_25162.1   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
13716JAK1 (Janus kinase 1 (a protein tyrosine kinase))60654.842-0.0036No
25781"PTPN11 (protein tyrosine phosphatase, non-receptor type 11)"66851.1180.0179No
33669ISG20 (interferon stimulated exonuclease gene 20kDa)148625.675-0.0101No
45770"PTPN1 (protein tyrosine phosphatase, non-receptor type 1)"264613.099-0.0610No
53661IRF3 (interferon regulatory factor 3)265513.086-0.0551No
63663IRF5 (interferon regulatory factor 5)53333.348-0.1856No
75777"PTPN6 (protein tyrosine phosphatase, non-receptor type 6)"69581.373-0.2651No
85696"PSMB8 (proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7))"72191.180-0.2773No
93443"IFNA6 (interferon, alpha 6)"77570.861-0.3034No
108651SOCS1 (suppressor of cytokine signaling 1)78250.822-0.3063No
113440"IFNA2 (interferon, alpha 2)"81440.676-0.3217No
123662IRF4 (interferon regulatory factor 4)88960.417-0.3586No
133442"IFNA5 (interferon, alpha 5)"99680.144-0.4114No
143446"IFNA10 (interferon, alpha 10)"10839-0.055-0.4543No
153439"IFNA1 (interferon, alpha 1)"11441-0.201-0.4838No
163445"IFNA8 (interferon, alpha 8)"11458-0.205-0.4845No
179021SOCS3 (suppressor of cytokine signaling 3)12244-0.385-0.5231No
183441"IFNA4 (interferon, alpha 4)"12451-0.445-0.5330No
193449"IFNA16 (interferon, alpha 16)"12618-0.489-0.5410No
203451"IFNA17 (interferon, alpha 17)"12711-0.517-0.5453No
214600MX2 (myxovirus (influenza virus) resistance 2 (mouse))13084-0.634-0.5633No
224599"MX1 (myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse))"13262-0.687-0.5717No
233444"IFNA7 (interferon, alpha 7)"13599-0.815-0.5879No
241958EGR1 (early growth response 1)13634-0.827-0.5892No
256041"RNASEL (ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent))"13797-0.896-0.5968No
2654739XAF1 (XIAP associated factor 1)14206-1.089-0.6164No
273448"IFNA14 (interferon, alpha 14)"14278-1.122-0.6193No
283452"IFNA21 (interferon, alpha 21)"14303-1.135-0.6200No
293456"IFNB1 (interferon, beta 1, fibroblast)"14732-1.384-0.6404No
303394IRF8 (interferon regulatory factor 8)15221-1.737-0.6637No
313454"IFNAR1 (interferon (alpha, beta and omega) receptor 1)"15684-2.132-0.6855No
328638OASL (2'-5'-oligoadenylate synthetase-like)16666-3.527-0.7322No
337297TYK2 (tyrosine kinase 2)16697-3.598-0.7319No
343433IFIT2 (interferon-induced protein with tetratricopeptide repeats 2)17164-4.656-0.7527No
353660IRF2 (interferon regulatory factor 2)17207-4.758-0.7525No
363664IRF6 (interferon regulatory factor 6)17986-7.831-0.7871No
373659IRF1 (interferon regulatory factor 1)18007-7.943-0.7843No
383665IRF7 (interferon regulatory factor 7)18746-13.575-0.8142Yes
3911274USP18 (ubiquitin specific peptidase 18)18861-14.702-0.8128Yes
402634"GBP2 (guanylate binding protein 2, interferon-inducible)"18868-14.825-0.8060Yes
413430IFI35 (interferon-induced protein 35)19007-16.958-0.8046Yes
423437IFIT3 (interferon-induced protein with tetratricopeptide repeats 3)19104-18.975-0.8003Yes
433134"HLA-F (major histocompatibility complex, class I, F)"19233-21.099-0.7965Yes
444939"OAS2 (2'-5'-oligoadenylate synthetase 2, 69/71kDa)"19395-25.501-0.7922Yes
456773"STAT2 (signal transducer and activator of transcription 2, 113kDa)"19399-25.624-0.7800Yes
463429"IFI27 (interferon, alpha-inducible protein 27)"19448-26.932-0.7695Yes
473133"HLA-E (major histocompatibility complex, class I, E)"19478-27.797-0.7576Yes
4851447IHPK2 (inositol hexaphosphate kinase 2)19516-28.829-0.7456Yes
492537"IFI6 (interferon, alpha-inducible protein 6)"19662-35.028-0.7359Yes
503135"HLA-G (major histocompatibility complex, class I, G)"19863-47.478-0.7230Yes
514938"OAS1 (2',5'-oligoadenylate synthetase 1, 40/46kDa)"19903-51.434-0.7002Yes
5210581IFITM2 (interferon induced transmembrane protein 2 (1-8D))19970-58.782-0.6753Yes
533105"HLA-A (major histocompatibility complex, class I, A)"20027-65.132-0.6468Yes
543106"HLA-B (major histocompatibility complex, class I, B)"20100-78.491-0.6127Yes
554940"OAS3 (2'-5'-oligoadenylate synthetase 3, 100kDa)"20125-86.843-0.5722Yes
568519IFITM1 (interferon induced transmembrane protein 1 (9-27))20204-117.578-0.5196Yes
57103"ADAR (adenosine deaminase, RNA-specific)"20231-134.677-0.4563Yes
583107"HLA-C (major histocompatibility complex, class I, C)"20243-142.867-0.3883Yes
5910379IRF9 (interferon regulatory factor 9)20262-164.279-0.3104Yes
6010410IFITM3 (interferon induced transmembrane protein 3 (1-8U))20271-173.958-0.2273Yes
613434IFIT1 (interferon-induced protein with tetratricopeptide repeats 1)20306-233.172-0.1171Yes
629636ISG15 (ISG15 ubiquitin-like modifier)20309-245.8520.0008Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME|REACT_25162.1   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME|REACT_25162.1: Random ES distribution   
Gene set null distribution of ES for REACTOME|REACT_25162.1