Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | KEGG|HSA04742 |
Enrichment Score (ES) | -0.76147676 |
Normalized Enrichment Score (NES) | -1.7053761 |
Nominal p-value | 0.0 |
FDR q-value | 0.12155658 |
FWER p-Value | 0.89 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 6337 | "SCNN1A (sodium channel, nonvoltage-gated 1 alpha)" | 4299 | 5.802 | -0.1973 | No | ||
2 | 5613 | "PRKX (protein kinase, X-linked)" | 4622 | 4.924 | -0.2007 | No | ||
3 | 5136 | "PDE1A (phosphodiesterase 1A, calmodulin-dependent)" | 6451 | 1.820 | -0.2862 | No | ||
4 | 50838 | "TAS2R13 (taste receptor, type 2, member 13)" | 7345 | 1.100 | -0.3275 | No | ||
5 | 259296 | "TAS2R50 (taste receptor, type 2, member 50)" | 7666 | 0.902 | -0.3410 | No | ||
6 | 114 | ADCY8 (adenylate cyclase 8 (brain)) | 7754 | 0.864 | -0.3431 | No | ||
7 | 80834 | "TAS1R2 (taste receptor, type 1, member 2)" | 7946 | 0.762 | -0.3506 | No | ||
8 | 50834 | "TAS2R1 (taste receptor, type 2, member 1)" | 7992 | 0.740 | -0.3509 | No | ||
9 | 3710 | "ITPR3 (inositol 1,4,5-triphosphate receptor, type 3)" | 8025 | 0.723 | -0.3507 | No | ||
10 | 259286 | "TAS2R40 (taste receptor, type 2, member 40)" | 8477 | 0.551 | -0.3715 | No | ||
11 | 5568 | "PRKACG (protein kinase, cAMP-dependent, catalytic, gamma)" | 8565 | 0.525 | -0.3745 | No | ||
12 | 50832 | "TAS2R4 (taste receptor, type 2, member 4)" | 8945 | 0.402 | -0.3922 | No | ||
13 | 259287 | "TAS2R41 (taste receptor, type 2, member 41)" | 9149 | 0.346 | -0.4013 | No | ||
14 | 2785 | "GNG3 (guanine nucleotide binding protein (G protein), gamma 3)" | 9305 | 0.303 | -0.4082 | No | ||
15 | 196883 | ADCY4 (adenylate cyclase 4) | 9849 | 0.170 | -0.4345 | No | ||
16 | 259294 | "TAS2R48 (taste receptor, type 2, member 48)" | 9934 | 0.150 | -0.4383 | No | ||
17 | 50836 | "TAS2R8 (taste receptor, type 2, member 8)" | 10244 | 0.075 | -0.4533 | No | ||
18 | 50837 | "TAS2R7 (taste receptor, type 2, member 7)" | 10667 | -0.018 | -0.4741 | No | ||
19 | 50831 | "TAS2R3 (taste receptor, type 2, member 3)" | 11187 | -0.141 | -0.4993 | No | ||
20 | 50840 | "TAS2R14 (taste receptor, type 2, member 14)" | 11245 | -0.153 | -0.5017 | No | ||
21 | 346562 | "GNAT3 (guanine nucleotide binding protein, alpha transducing 3)" | 11473 | -0.208 | -0.5124 | No | ||
22 | 50835 | "TAS2R9 (taste receptor, type 2, member 9)" | 11490 | -0.211 | -0.5127 | No | ||
23 | 3745 | "KCNB1 (potassium voltage-gated channel, Shab-related subfamily, member 1)" | 11571 | -0.228 | -0.5160 | No | ||
24 | 50839 | "TAS2R10 (taste receptor, type 2, member 10)" | 12926 | -0.584 | -0.5813 | No | ||
25 | 774 | "CACNA1B (calcium channel, voltage-dependent, N type, alpha 1B subunit)" | 13537 | -0.789 | -0.6094 | No | ||
26 | 54429 | "TAS2R5 (taste receptor, type 2, member 5)" | 13540 | -0.791 | -0.6075 | No | ||
27 | 259285 | "TAS2R39 (taste receptor, type 2, member 39)" | 13590 | -0.811 | -0.6078 | No | ||
28 | 50833 | "TAS2R16 (taste receptor, type 2, member 16)" | 14006 | -0.999 | -0.6258 | No | ||
29 | 6340 | "SCNN1G (sodium channel, nonvoltage-gated 1, gamma)" | 14089 | -1.041 | -0.6272 | No | ||
30 | 5726 | "TAS2R38 (taste receptor, type 2, member 38)" | 14164 | -1.072 | -0.6281 | No | ||
31 | 6338 | "SCNN1B (sodium channel, nonvoltage-gated 1, beta)" | 14445 | -1.207 | -0.6389 | No | ||
32 | 40 | "ACCN1 (amiloride-sensitive cation channel 1, neuronal)" | 14585 | -1.287 | -0.6425 | No | ||
33 | 80835 | "TAS1R1 (taste receptor, type 1, member 1)" | 14683 | -1.348 | -0.6439 | No | ||
34 | 29850 | "TRPM5 (transient receptor potential cation channel, subfamily M, member 5)" | 15561 | -2.024 | -0.6820 | No | ||
35 | 51764 | "GNG13 (guanine nucleotide binding protein (G protein), gamma 13)" | 16012 | -2.512 | -0.6978 | No | ||
36 | 5330 | "PLCB2 (phospholipase C, beta 2)" | 16712 | -3.624 | -0.7231 | No | ||
37 | 773 | "CACNA1A (calcium channel, voltage-dependent, P/Q type, alpha 1A subunit)" | 17205 | -4.752 | -0.7354 | No | ||
38 | 2782 | "GNB1 (guanine nucleotide binding protein (G protein), beta polypeptide 1)" | 17381 | -5.227 | -0.7308 | No | ||
39 | 2784 | "GNB3 (guanine nucleotide binding protein (G protein), beta polypeptide 3)" | 17419 | -5.344 | -0.7191 | No | ||
40 | 5566 | "PRKACA (protein kinase, cAMP-dependent, catalytic, alpha)" | 18280 | -9.482 | -0.7375 | Yes | ||
41 | 2914 | "GRM4 (glutamate receptor, metabotropic 4)" | 18451 | -10.801 | -0.7186 | Yes | ||
42 | 112 | ADCY6 (adenylate cyclase 6) | 18936 | -15.810 | -0.7025 | Yes | ||
43 | 5567 | "PRKACB (protein kinase, cAMP-dependent, catalytic, beta)" | 19040 | -17.599 | -0.6630 | Yes | ||
44 | 2778 | GNAS (GNAS complex locus) | 20315 | -287.233 | 0.0005 | Yes |