Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | REACTOME|REACT_1281.3 |
Enrichment Score (ES) | 0.789891 |
Normalized Enrichment Score (NES) | 1.6398311 |
Nominal p-value | 0.0014534884 |
FDR q-value | 0.03293844 |
FWER p-Value | 0.831 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 6432 | "SFRS7 (splicing factor, arginine/serine-rich 7, 35kDa)" | 38 | 213.976 | 0.1067 | Yes | ||
2 | 6426 | "SFRS1 (splicing factor, arginine/serine-rich 1)" | 119 | 133.017 | 0.1702 | Yes | ||
3 | 10189 | THOC4 (THO complex 4) | 158 | 117.078 | 0.2278 | Yes | ||
4 | 9939 | RBM8A (RNA binding motif protein 8A) | 201 | 102.613 | 0.2778 | Yes | ||
5 | 6427 | "SFRS2 (splicing factor, arginine/serine-rich 2)" | 273 | 90.107 | 0.3200 | Yes | ||
6 | 57122 | NUP107 (nucleoporin 107kDa) | 276 | 89.588 | 0.3653 | Yes | ||
7 | 6428 | "SFRS3 (splicing factor, arginine/serine-rich 3)" | 302 | 85.664 | 0.4076 | Yes | ||
8 | 1977 | EIF4E (eukaryotic translation initiation factor 4E) | 306 | 84.641 | 0.4504 | Yes | ||
9 | 8480 | RAE1 (RAE1 RNA export 1 homolog (S. pombe)) | 322 | 83.312 | 0.4919 | Yes | ||
10 | 129401 | NUP35 (nucleoporin 35kDa) | 502 | 61.873 | 0.5144 | Yes | ||
11 | 7307 | U2AF1 (U2 small nuclear RNA auxiliary factor 1) | 509 | 61.555 | 0.5454 | Yes | ||
12 | 79023 | NUP37 (nucleoporin 37kDa) | 770 | 46.189 | 0.5560 | Yes | ||
13 | 4686 | "NCBP1 (nuclear cap binding protein subunit 1, 80kDa)" | 860 | 42.266 | 0.5730 | Yes | ||
14 | 9972 | NUP153 (nucleoporin 153kDa) | 924 | 39.672 | 0.5901 | Yes | ||
15 | 7884 | SLBP (stem-loop binding protein) | 966 | 37.985 | 0.6073 | Yes | ||
16 | 23636 | NUP62 (nucleoporin 62kDa) | 980 | 37.692 | 0.6258 | Yes | ||
17 | 22916 | "NCBP2 (nuclear cap binding protein subunit 2, 20kDa)" | 986 | 37.528 | 0.6446 | Yes | ||
18 | 4116 | "MAGOH (mago-nashi homolog, proliferation-associated (Drosophila))" | 1009 | 36.619 | 0.6621 | Yes | ||
19 | 9295 | "SFRS11 (splicing factor, arginine/serine-rich 11)" | 1042 | 35.388 | 0.6785 | Yes | ||
20 | 10921 | "RNPS1 (RNA binding protein S1, serine-rich domain)" | 1107 | 33.536 | 0.6923 | Yes | ||
21 | 11338 | U2AF2 (U2 small nuclear RNA auxiliary factor 2) | 1112 | 33.372 | 0.7091 | Yes | ||
22 | 10762 | NUP50 (nucleoporin 50kDa) | 1132 | 32.860 | 0.7248 | Yes | ||
23 | 23165 | NUP205 (nucleoporin 205kDa) | 1143 | 32.605 | 0.7408 | Yes | ||
24 | 4927 | NUP88 (nucleoporin 88kDa) | 1149 | 32.455 | 0.7571 | Yes | ||
25 | 53371 | NUP54 (nucleoporin 54kDa) | 1604 | 23.859 | 0.7468 | Yes | ||
26 | 9631 | NUP155 (nucleoporin 155kDa) | 1641 | 23.360 | 0.7569 | Yes | ||
27 | 65109 | UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast)) | 1778 | 21.341 | 0.7610 | Yes | ||
28 | 23279 | NUP160 (nucleoporin 160kDa) | 1804 | 20.988 | 0.7704 | Yes | ||
29 | 6429 | "SFRS4 (splicing factor, arginine/serine-rich 4)" | 1970 | 19.104 | 0.7719 | Yes | ||
30 | 51362 | CDC40 (cell division cycle 40 homolog (S. cerevisiae)) | 2098 | 17.942 | 0.7748 | Yes | ||
31 | 6431 | "SFRS6 (splicing factor, arginine/serine-rich 6)" | 2113 | 17.800 | 0.7831 | Yes | ||
32 | 5903 | RANBP2 (RAN binding protein 2) | 2164 | 17.399 | 0.7895 | Yes | ||
33 | 23511 | NUP188 (nucleoporin 188kDa) | 2623 | 13.256 | 0.7736 | Yes | ||
34 | 9688 | NUP93 (nucleoporin 93kDa) | 2709 | 12.814 | 0.7759 | Yes | ||
35 | 29894 | "CPSF1 (cleavage and polyadenylation specific factor 1, 160kDa)" | 2720 | 12.711 | 0.7819 | Yes | ||
36 | 55746 | NUP133 (nucleoporin 133kDa) | 2787 | 12.281 | 0.7849 | Yes | ||
37 | 10482 | NXF1 (nuclear RNA export factor 1) | 2811 | 12.145 | 0.7899 | Yes | ||
38 | 79902 | NUP85 (nucleoporin 85kDa) | 3289 | 9.586 | 0.7712 | No | ||
39 | 51692 | "CPSF3 (cleavage and polyadenylation specific factor 3, 73kDa)" | 3299 | 9.533 | 0.7756 | No | ||
40 | 348995 | NUP43 (nucleoporin 43kDa) | 3355 | 9.350 | 0.7777 | No | ||
41 | 23225 | NUP210 (nucleoporin 210kDa) | 3396 | 9.169 | 0.7803 | No | ||
42 | 10250 | SRRM1 (serine/arginine repetitive matrix 1) | 3484 | 8.795 | 0.7805 | No | ||
43 | 9883 | POM121 (POM121 membrane glycoprotein (rat)) | 5027 | 3.978 | 0.7065 | No | ||
44 | 9785 | DHX38 (DEAH (Asp-Glu-Ala-His) box polypeptide 38) | 14908 | -1.491 | 0.2199 | No | ||
45 | 53981 | "CPSF2 (cleavage and polyadenylation specific factor 2, 100kDa)" | 15120 | -1.654 | 0.2104 | No | ||
46 | 8021 | NUP214 (nucleoporin 214kDa) | 16014 | -2.513 | 0.1676 | No | ||
47 | 8086 | "AAAS (achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A))" | 16985 | -4.211 | 0.1219 | No | ||
48 | 7175 | TPR (translocated promoter region (to activated MET oncogene)) | 17416 | -5.336 | 0.1034 | No | ||
49 | 11097 | NUPL2 (nucleoporin like 2) | 18164 | -8.850 | 0.0710 | No | ||
50 | 8683 | "SFRS9 (splicing factor, arginine/serine-rich 9)" | 18964 | -16.250 | 0.0399 | No | ||
51 | 6430 | "SFRS5 (splicing factor, arginine/serine-rich 5)" | 19923 | -53.636 | 0.0198 | No |