Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classtreated
GeneSetREACTOME|REACT_1753.2
Enrichment Score (ES)0.8243211
Normalized Enrichment Score (NES)1.6919174
Nominal p-value0.0
FDR q-value0.016429085
FWER p-Value0.282
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME|REACT_1753.2   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
16432"SFRS7 (splicing factor, arginine/serine-rich 7, 35kDa)"38213.9760.0957Yes
26635SNRPE (small nuclear ribonucleoprotein polypeptide E)43207.4330.1901Yes
36636SNRPF (small nuclear ribonucleoprotein polypeptide F)93154.3880.2581Yes
46426"SFRS1 (splicing factor, arginine/serine-rich 1)"119133.0170.3175Yes
54809NHP2L1 (NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae))162113.7000.3673Yes
66634SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide 18kDa)196103.4340.4128Yes
751639"SF3B14 (splicing factor 3B, 14 kDa subunit)"23296.6860.4552Yes
85431"POLR2B (polymerase (RNA) II (DNA directed) polypeptide B, 140kDa)"24893.7050.4972Yes
96427"SFRS2 (splicing factor, arginine/serine-rich 2)"27390.1070.5371Yes
1010907TXNL4A (thioredoxin-like 4A)28388.4840.5770Yes
116632SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide 16kDa)35278.9030.6096Yes
125436POLR2G (polymerase (RNA) II (DNA directed) polypeptide G)43967.7680.6362Yes
136633SNRPD2 (small nuclear ribonucleoprotein D2 polypeptide 16.5kDa)52860.4710.6595Yes
145435POLR2F (polymerase (RNA) II (DNA directed) polypeptide F)53160.3460.6869Yes
1583443"SF3B5 (splicing factor 3b, subunit 5, 10kDa)"60554.8530.7083Yes
165441"POLR2L (polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa)"65551.8330.7295Yes
176628SNRPB (small nuclear ribonucleoprotein polypeptides B and B1)69749.7170.7502Yes
1823450"SF3B3 (splicing factor 3b, subunit 3, 130kDa)"71148.6050.7717Yes
194686"NCBP1 (nuclear cap binding protein subunit 1, 80kDa)"86042.2660.7837Yes
2010262"SF3B4 (splicing factor 3b, subunit 4, 49kDa)"88241.2580.8015Yes
2122916"NCBP2 (nuclear cap binding protein subunit 2, 20kDa)"98637.5280.8135Yes
225438"POLR2I (polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa)"115732.2490.8198Yes
235434"POLR2E (polymerase (RNA) II (DNA directed) polypeptide E, 25kDa)"132828.2680.8243Yes
245433POLR2D (polymerase (RNA) II (DNA directed) polypeptide D)174721.7110.8136No
255432"POLR2C (polymerase (RNA) II (DNA directed) polypeptide C, 33kDa)"177221.3890.8222No
262963"GTF2F2 (general transcription factor IIF, polypeptide 2, 30kDa)"205618.2640.8166No
276431"SFRS6 (splicing factor, arginine/serine-rich 6)"211317.8000.8219No
289410WDR57 (WD repeat domain 57 (U5 snRNP specific))243414.8490.8129No
299416DDX23 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 23)265313.0870.8081No
3057819"LSM2 (LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae))"313610.2510.7890No
319343EFTUD2 (elongation factor Tu GTP binding domain containing 2)36178.2800.7691No
325430"POLR2A (polymerase (RNA) II (DNA directed) polypeptide A, 220kDa)"36268.2310.7725No
335437POLR2H (polymerase (RNA) II (DNA directed) polypeptide H)45965.0000.7270No
345440"POLR2K (polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa)"63211.9700.6429No
352962"GTF2F1 (general transcription factor IIF, polypeptide 1, 74kDa)"63881.8940.6405No
36652147"LOC652147 (similar to U5 snRNP-specific protein, 200 kDa)"65321.7500.6343No
3723451"SF3B1 (splicing factor 3b, subunit 1, 155kDa)"15886-2.3480.1742No
3810594PRPF8 (PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae))17881-7.2460.0792No
395439"POLR2J (polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa)"18134-8.6610.0707No
4024148PRPF6 (PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae))18644-12.5100.0513No
4110992"SF3B2 (splicing factor 3b, subunit 2, 145kDa)"19037-17.5760.0400No
426637SNRPG (small nuclear ribonucleoprotein polypeptide G)19107-18.9860.0453No
4323020ASCC3L1 (activating signal cointegrator 1 complex subunit 3-like 1)19614-32.2610.0351No
Table: GSEA details [plain text format]



Fig 2: REACTOME|REACT_1753.2   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME|REACT_1753.2: Random ES distribution   
Gene set null distribution of ES for REACTOME|REACT_1753.2