Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetGO|GO:0031295
Enrichment Score (ES)-0.68730354
Normalized Enrichment Score (NES)-1.6133931
Nominal p-value0.0062111802
FDR q-value0.24435794
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: GO|GO:0031295   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
15781"PTPN11 (protein tyrosine phosphatase, non-receptor type 11)"66851.1180.0216No
21445CSK (c-src tyrosine kinase)127629.5810.0231No
379109MAPKAP1 (mitogen-activated protein kinase associated protein 1)195419.3980.0104No
47525YES1 (v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1)198718.9100.0290No
53123"HLA-DRB1 (major histocompatibility complex, class II, DR beta 1)"257913.6550.0144No
6857"CAV1 (caveolin 1, caveolae protein, 22kDa)"34069.137-0.0166No
72534"FYN (FYN oncogene related to SRC, FGR, YES)"42445.992-0.0515No
828755TRAC (T cell receptor alpha constant)42495.969-0.0454No
93126"HLA-DRB4 (major histocompatibility complex, class II, DR beta 4)"43715.560-0.0454No
101326MAP3K8 (mitogen-activated protein kinase kinase kinase 8)50723.886-0.0758No
112475FRAP1 (FK506 binding protein 12-rapamycin associated protein 1)51353.745-0.0749No
123127"HLA-DRB5 (major histocompatibility complex, class II, DR beta 5)"60782.255-0.1189No
138764"TNFRSF14 (tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator))"60832.252-0.1167No
143113"HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)"64331.847-0.1320No
155777"PTPN6 (protein tyrosine phosphatase, non-receptor type 6)"69581.373-0.1564No
1623308ICOSLG (inducible T-cell co-stimulator ligand)70811.283-0.1610No
1729126CD274 (CD274 molecule)72171.181-0.1664No
181803DPP4 (dipeptidyl-peptidase 4)73511.095-0.1718No
195058PAK1 (p21 protein (Cdc42/Rac)-activated kinase 1)76460.920-0.1854No
2022914"KLRK1 (killer cell lectin-like receptor subfamily K, member 1)"76720.900-0.1856No
21915"CD3D (CD3d molecule, delta (CD3-TCR complex))"80760.700-0.2048No
223932LCK (lymphocyte-specific protein tyrosine kinase)86020.511-0.2301No
233115"HLA-DPB1 (major histocompatibility complex, class II, DP beta 1)"89030.414-0.2445No
24919CD247 (CD247 molecule)98650.167-0.2918No
25942CD86 (CD86 molecule)10585-0.000-0.3272No
266714SRC (v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian))11110-0.124-0.3530No
27940CD28 (CD28 molecule)12034-0.333-0.3982No
28920CD4 (CD4 molecule)12457-0.446-0.4185No
296363CCL19 (chemokine (C-C motif) ligand 19)12834-0.556-0.4365No
30941CD80 (CD80 molecule)13279-0.692-0.4576No
313112"HLA-DOB (major histocompatibility complex, class II, DO beta)"13515-0.781-0.4684No
323108"HLA-DMA (major histocompatibility complex, class II, DM alpha)"13572-0.805-0.4703No
33151888BTLA (B and T lymphocyte associated)13780-0.890-0.4796No
3429851ICOS (inducible T-cell co-stimulator)13924-0.962-0.4856No
359020MAP3K14 (mitogen-activated protein kinase kinase kinase 14)14010-1.000-0.4887No
367409VAV1 (vav 1 guanine nucleotide exchange factor)14093-1.044-0.4917No
376366CCL21 (chemokine (C-C motif) ligand 21)14126-1.061-0.4921No
385133PDCD1 (programmed cell death 1)14292-1.129-0.4991No
393109"HLA-DMB (major histocompatibility complex, class II, DM beta)"14469-1.219-0.5064No
40917"CD3G (CD3g molecule, gamma (CD3-TCR complex))"14522-1.255-0.5077No
411236CCR7 (chemokine (C-C motif) receptor 7)14816-1.429-0.5206No
4284433"CARD11 (caspase recruitment domain family, member 11)"14839-1.444-0.5201No
431493CTLA4 (cytotoxic T-lymphocyte-associated protein 4)15552-2.011-0.5531No
4480380PDCD1LG2 (programmed cell death 1 ligand 2)15782-2.243-0.5620No
45253260RICTOR (rapamycin-insensitive companion of mTOR)16150-2.699-0.5773No
469402GRAP2 (GRB2-related adaptor protein 2)16323-2.949-0.5826No
472885GRB2 (growth factor receptor-bound protein 2)16385-3.037-0.5824No
48916"CD3E (CD3e molecule, epsilon (CD3-TCR complex))"16842-3.845-0.6008No
493111"HLA-DOA (major histocompatibility complex, class II, DO alpha)"17650-6.220-0.6340No
5064223GBL (G protein beta subunit-like)17731-6.592-0.6309No
515290"PIK3CA (phosphoinositide-3-kinase, catalytic, alpha polypeptide)"17764-6.773-0.6253No
523122"HLA-DRA (major histocompatibility complex, class II, DR alpha)"17997-7.888-0.6283No
534067LYN (v-yes-1 Yamaguchi sarcoma viral related oncogene homolog)18419-10.518-0.6379No
545295"PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1 (alpha))"19422-26.295-0.6593Yes
55207AKT1 (v-akt murine thymoma viral oncogene homolog 1)19588-31.123-0.6342Yes
565879"RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))"19612-32.214-0.6010Yes
575062PAK2 (p21 protein (Cdc42/Rac)-activated kinase 2)19777-40.918-0.5654Yes
585170PDPK1 (3-phosphoinositide dependent protein kinase-1)19867-47.955-0.5187Yes
595296"PIK3R2 (phosphoinositide-3-kinase, regulatory subunit 2 (beta))"19918-53.218-0.4644Yes
60998"CDC42 (cell division cycle 42 (GTP binding protein, 25kDa))"20112-82.496-0.3860Yes
618503"PIK3R3 (phosphoinositide-3-kinase, regulatory subunit 3 (gamma))"20275-179.372-0.2027Yes
62100133941CD24 (CD24 molecule)20284-192.2870.0020Yes
Table: GSEA details [plain text format]



Fig 2: GO|GO:0031295   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GO|GO:0031295: Random ES distribution   
Gene set null distribution of ES for GO|GO:0031295