Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classcont
GeneSetKEGG|HSA05330
Enrichment Score (ES)-0.7976374
Normalized Enrichment Score (NES)-1.6895369
Nominal p-value0.0
FDR q-value0.15671079
FWER p-Value0.96
Table: GSEA Results Summary



Fig 1: Enrichment plot: KEGG|HSA05330   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
13123"HLA-DRB1 (major histocompatibility complex, class II, DR beta 1)"257913.655-0.0967No
2355"FAS (Fas (TNF receptor superfamily, member 6))"38027.517-0.1403No
33126"HLA-DRB4 (major histocompatibility complex, class II, DR beta 4)"43715.560-0.1559No
43127"HLA-DRB5 (major histocompatibility complex, class II, DR beta 5)"60782.255-0.2349No
53113"HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)"64331.847-0.2483No
63558IL2 (interleukin 2)83650.590-0.3421No
73115"HLA-DPB1 (major histocompatibility complex, class II, DP beta 1)"89030.414-0.3677No
8356"FASLG (Fas ligand (TNF superfamily, member 6))"91550.344-0.3793No
95551PRF1 (perforin 1 (pore forming protein))93140.302-0.3864No
103586IL10 (interleukin 10)98010.182-0.4100No
113458"IFNG (interferon, gamma)"98350.174-0.4112No
123002"GZMB (granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1))"104540.024-0.4416No
13942CD86 (CD86 molecule)10585-0.000-0.4480No
143117"HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1)"10965-0.086-0.4665No
153593"IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))"11374-0.185-0.4862No
163119"HLA-DQB1 (major histocompatibility complex, class II, DQ beta 1)"11665-0.252-0.4999No
173567"IL5 (interleukin 5 (colony-stimulating factor, eosinophil))"11758-0.272-0.5039No
183592"IL12A (interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35))"12016-0.327-0.5158No
19940CD28 (CD28 molecule)12034-0.333-0.5159No
207124"TNF (tumor necrosis factor (TNF superfamily, member 2))"12777-0.537-0.5513No
21941CD80 (CD80 molecule)13279-0.692-0.5744No
223112"HLA-DOB (major histocompatibility complex, class II, DO beta)"13515-0.781-0.5843No
233108"HLA-DMA (major histocompatibility complex, class II, DM alpha)"13572-0.805-0.5852No
243109"HLA-DMB (major histocompatibility complex, class II, DM beta)"14469-1.219-0.6267No
253565IL4 (interleukin 4)14888-1.480-0.6440No
26959CD40LG (CD40 ligand)16596-3.395-0.7206No
273111"HLA-DOA (major histocompatibility complex, class II, DO alpha)"17650-6.220-0.7586Yes
283122"HLA-DRA (major histocompatibility complex, class II, DR alpha)"17997-7.888-0.7581Yes
29958"CD40 (CD40 molecule, TNF receptor superfamily member 5)"18296-9.590-0.7515Yes
303134"HLA-F (major histocompatibility complex, class I, F)"19233-21.099-0.7507Yes
313133"HLA-E (major histocompatibility complex, class I, E)"19478-27.797-0.7010Yes
323135"HLA-G (major histocompatibility complex, class I, G)"19863-47.478-0.6143Yes
333105"HLA-A (major histocompatibility complex, class I, A)"20027-65.132-0.4776Yes
343106"HLA-B (major histocompatibility complex, class I, B)"20100-78.491-0.3066Yes
353107"HLA-C (major histocompatibility complex, class I, C)"20243-142.8670.0040Yes
Table: GSEA details [plain text format]



Fig 2: KEGG|HSA05330   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KEGG|HSA05330: Random ES distribution   
Gene set null distribution of ES for KEGG|HSA05330