Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
| Phenotype | Phenotype.cls#treated_versus_cont_repos |
| Upregulated in class | cont |
| GeneSet | GO|GO:0000139 |
| Enrichment Score (ES) | -0.59347 |
| Normalized Enrichment Score (NES) | -1.5864801 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.29423037 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 11079 | RER1 (RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)) | 594 | 55.501 | -0.0079 | No | ||
| 2 | 4247 | "MGAT2 (mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase)" | 723 | 48.109 | 0.0044 | No | ||
| 3 | 51360 | "MBTPS2 (membrane-bound transcription factor peptidase, site 2)" | 762 | 46.699 | 0.0206 | No | ||
| 4 | 2683 | "B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1)" | 791 | 45.228 | 0.0368 | No | ||
| 5 | 347734 | "SLC35B2 (solute carrier family 35, member B2)" | 1750 | 21.631 | -0.0023 | No | ||
| 6 | 51463 | GPR89B (G protein-coupled receptor 89B) | 1781 | 21.333 | 0.0045 | No | ||
| 7 | 162 | "AP1B1 (adaptor-related protein complex 1, beta 1 subunit)" | 2020 | 18.565 | -0.0001 | No | ||
| 8 | 79694 | "MANEA (mannosidase, endo-alpha)" | 2097 | 17.944 | 0.0031 | No | ||
| 9 | 8704 | "B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2)" | 2170 | 17.370 | 0.0062 | No | ||
| 10 | 64924 | "SLC30A5 (solute carrier family 30 (zinc transporter), member 5)" | 2175 | 17.345 | 0.0127 | No | ||
| 11 | 55331 | "PHCA (phytoceramidase, alkaline)" | 2187 | 17.237 | 0.0189 | No | ||
| 12 | 1315 | "COPB1 (coatomer protein complex, subunit beta 1)" | 2207 | 17.085 | 0.0246 | No | ||
| 13 | 8905 | "AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)" | 2240 | 16.745 | 0.0295 | No | ||
| 14 | 7355 | "SLC35A2 (solute carrier family 35 (UDP-galactose transporter), member A2)" | 2312 | 15.924 | 0.0321 | No | ||
| 15 | 5154 | PDGFA (platelet-derived growth factor alpha polypeptide) | 2345 | 15.551 | 0.0366 | No | ||
| 16 | 22926 | ATF6 (activating transcription factor 6) | 2528 | 14.054 | 0.0330 | No | ||
| 17 | 11316 | "COPE (coatomer protein complex, subunit epsilon)" | 2539 | 13.982 | 0.0379 | No | ||
| 18 | 148867 | "SLC30A7 (solute carrier family 30 (zinc transporter), member 7)" | 2636 | 13.182 | 0.0383 | No | ||
| 19 | 340481 | "ZDHHC21 (zinc finger, DHHC-type containing 21)" | 2657 | 13.082 | 0.0424 | No | ||
| 20 | 11041 | "B3GNT1 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)" | 2705 | 12.846 | 0.0450 | No | ||
| 21 | 205428 | C3orf58 (chromosome 3 open reading frame 58) | 2857 | 11.918 | 0.0422 | No | ||
| 22 | 26958 | "COPG2 (coatomer protein complex, subunit gamma 2)" | 2929 | 11.459 | 0.0431 | No | ||
| 23 | 10675 | CSPG5 (chondroitin sulfate proteoglycan 5 (neuroglycan C)) | 2932 | 11.420 | 0.0474 | No | ||
| 24 | 9197 | "SLC33A1 (solute carrier family 33 (acetyl-CoA transporter), member 1)" | 2969 | 11.171 | 0.0500 | No | ||
| 25 | 8703 | "B4GALT3 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3)" | 3056 | 10.696 | 0.0498 | No | ||
| 26 | 8907 | "AP1M1 (adaptor-related protein complex 1, mu 1 subunit)" | 3145 | 10.205 | 0.0494 | No | ||
| 27 | 57410 | SCYL1 (SCY1-like 1 (S. cerevisiae)) | 3146 | 10.195 | 0.0534 | No | ||
| 28 | 653519 | GPR89A (G protein-coupled receptor 89A) | 3170 | 10.081 | 0.0562 | No | ||
| 29 | 4121 | "MAN1A1 (mannosidase, alpha, class 1A, member 1)" | 3210 | 9.907 | 0.0581 | No | ||
| 30 | 857 | "CAV1 (caveolin 1, caveolae protein, 22kDa)" | 3406 | 9.137 | 0.0519 | No | ||
| 31 | 55676 | "SLC30A6 (solute carrier family 30 (zinc transporter), member 6)" | 3624 | 8.241 | 0.0444 | No | ||
| 32 | 130340 | "AP1S3 (adaptor-related protein complex 1, sigma 3 subunit)" | 3774 | 7.615 | 0.0400 | No | ||
| 33 | 84912 | "SLC35B4 (solute carrier family 35, member B4)" | 3784 | 7.576 | 0.0424 | No | ||
| 34 | 53947 | "A4GALT (alpha 1,4-galactosyltransferase)" | 3893 | 7.115 | 0.0399 | No | ||
| 35 | 2590 | GALNT2 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)) | 4049 | 6.637 | 0.0347 | No | ||
| 36 | 27032 | "ATP2C1 (ATPase, Ca++ transporting, type 2C, member 1)" | 4080 | 6.513 | 0.0358 | No | ||
| 37 | 1785 | DNM2 (dynamin 2) | 4319 | 5.715 | 0.0262 | No | ||
| 38 | 9215 | LARGE (like-glycosyltransferase) | 4321 | 5.712 | 0.0284 | No | ||
| 39 | 1174 | "AP1S1 (adaptor-related protein complex 1, sigma 1 subunit)" | 4682 | 4.756 | 0.0124 | No | ||
| 40 | 160 | "AP2A1 (adaptor-related protein complex 2, alpha 1 subunit)" | 4698 | 4.725 | 0.0135 | No | ||
| 41 | 23563 | CHST5 (carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5) | 4805 | 4.463 | 0.0099 | No | ||
| 42 | 408 | "ARRB1 (arrestin, beta 1)" | 4928 | 4.173 | 0.0055 | No | ||
| 43 | 26229 | "B3GAT3 (beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I))" | 4962 | 4.107 | 0.0055 | No | ||
| 44 | 22818 | "COPZ1 (coatomer protein complex, subunit zeta 1)" | 4971 | 4.094 | 0.0067 | No | ||
| 45 | 4124 | "MAN2A1 (mannosidase, alpha, class 2A, member 1)" | 5051 | 3.919 | 0.0043 | No | ||
| 46 | 5155 | PDGFB (platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)) | 5374 | 3.286 | -0.0104 | No | ||
| 47 | 55738 | ARFGAP1 (ADP-ribosylation factor GTPase activating protein 1) | 5492 | 3.077 | -0.0150 | No | ||
| 48 | 10066 | SCAMP2 (secretory carrier membrane protein 2) | 5543 | 3.000 | -0.0164 | No | ||
| 49 | 8720 | "MBTPS1 (membrane-bound transcription factor peptidase, site 1)" | 5640 | 2.856 | -0.0200 | No | ||
| 50 | 51070 | NOSIP (nitric oxide synthase interacting protein) | 5770 | 2.660 | -0.0254 | No | ||
| 51 | 9570 | GOSR2 (golgi SNAP receptor complex member 2) | 5799 | 2.617 | -0.0257 | No | ||
| 52 | 8702 | "B4GALT4 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4)" | 6409 | 1.867 | -0.0552 | No | ||
| 53 | 63971 | KIF13A (kinesin family member 13A) | 6447 | 1.822 | -0.0563 | No | ||
| 54 | 10564 | ARFGEF2 (ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)) | 6631 | 1.647 | -0.0648 | No | ||
| 55 | 9331 | "B4GALT6 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6)" | 6791 | 1.520 | -0.0721 | No | ||
| 56 | 9334 | "B4GALT5 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5)" | 7075 | 1.290 | -0.0856 | No | ||
| 57 | 23162 | MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3) | 7448 | 1.035 | -0.1036 | No | ||
| 58 | 10905 | "MAN1A2 (mannosidase, alpha, class 1A, member 2)" | 7553 | 0.966 | -0.1084 | No | ||
| 59 | 55790 | CSGALNACT1 (chondroitin sulfate N-acetylgalactosaminyltransferase 1) | 7725 | 0.877 | -0.1165 | No | ||
| 60 | 28 | "ABO (ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase))" | 7942 | 0.764 | -0.1269 | No | ||
| 61 | 22820 | "COPG (coatomer protein complex, subunit gamma)" | 8040 | 0.715 | -0.1315 | No | ||
| 62 | 9435 | CHST2 (carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2) | 8049 | 0.709 | -0.1316 | No | ||
| 63 | 166929 | SGMS2 (sphingomyelin synthase 2) | 8212 | 0.650 | -0.1394 | No | ||
| 64 | 84679 | "SLC9A7 (solute carrier family 9 (sodium/hydrogen exchanger), member 7)" | 8246 | 0.634 | -0.1408 | No | ||
| 65 | 4684 | NCAM1 (neural cell adhesion molecule 1) | 8322 | 0.605 | -0.1442 | No | ||
| 66 | 56034 | PDGFC (platelet derived growth factor C) | 8825 | 0.436 | -0.1690 | No | ||
| 67 | 8906 | "AP1G2 (adaptor-related protein complex 1, gamma 2 subunit)" | 8858 | 0.428 | -0.1704 | No | ||
| 68 | 8128 | "ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2)" | 8928 | 0.407 | -0.1736 | No | ||
| 69 | 192683 | SCAMP5 (secretory carrier membrane protein 5) | 9000 | 0.386 | -0.1770 | No | ||
| 70 | 55454 | CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2) | 9325 | 0.298 | -0.1930 | No | ||
| 71 | 6456 | SH3GL2 (SH3-domain GRB2-like 2) | 9550 | 0.241 | -0.2040 | No | ||
| 72 | 83988 | NCALD (neurocalcin delta) | 9741 | 0.197 | -0.2133 | No | ||
| 73 | 340273 | "ABCB5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5)" | 9780 | 0.186 | -0.2151 | No | ||
| 74 | 25834 | "MGAT4C (mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative))" | 10026 | 0.128 | -0.2272 | No | ||
| 75 | 51046 | "ST8SIA3 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3)" | 10156 | 0.096 | -0.2336 | No | ||
| 76 | 23057 | NMNAT2 (nicotinamide nucleotide adenylyltransferase 2) | 10599 | -0.003 | -0.2555 | No | ||
| 77 | 55016 | MARCH1 (membrane-associated ring finger (C3HC4) 1) | 10672 | -0.020 | -0.2590 | No | ||
| 78 | 27315 | FRAG1 (FGF receptor activating protein 1) | 10746 | -0.035 | -0.2626 | No | ||
| 79 | 25999 | CLIP3 (CAP-GLY domain containing linker protein 3) | 11138 | -0.129 | -0.2820 | No | ||
| 80 | 10164 | CHST4 (carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4) | 11287 | -0.162 | -0.2892 | No | ||
| 81 | 5243 | "ABCB1 (ATP-binding cassette, sub-family B (MDR/TAP), member 1)" | 11576 | -0.229 | -0.3034 | No | ||
| 82 | 8647 | "ABCB11 (ATP-binding cassette, sub-family B (MDR/TAP), member 11)" | 11670 | -0.253 | -0.3079 | No | ||
| 83 | 4249 | "MGAT5 (mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase)" | 11859 | -0.294 | -0.3171 | No | ||
| 84 | 261729 | STEAP2 (six transmembrane epithelial antigen of the prostate 2) | 12567 | -0.474 | -0.3520 | No | ||
| 85 | 54503 | "ZDHHC13 (zinc finger, DHHC-type containing 13)" | 12650 | -0.499 | -0.3559 | No | ||
| 86 | 4846 | NOS3 (nitric oxide synthase 3 (endothelial cell)) | 12844 | -0.558 | -0.3652 | No | ||
| 87 | 2697 | "GJA1 (gap junction protein, alpha 1, 43kDa)" | 13031 | -0.617 | -0.3742 | No | ||
| 88 | 9182 | RASSF9 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 9) | 13400 | -0.741 | -0.3922 | No | ||
| 89 | 4248 | "MGAT3 (mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase)" | 13452 | -0.761 | -0.3944 | No | ||
| 90 | 5244 | "ABCB4 (ATP-binding cassette, sub-family B (MDR/TAP), member 4)" | 14018 | -1.004 | -0.4220 | No | ||
| 91 | 7851 | "MALL (mal, T-cell differentiation protein-like)" | 14373 | -1.171 | -0.4391 | No | ||
| 92 | 80310 | PDGFD (platelet derived growth factor D) | 14589 | -1.289 | -0.4493 | No | ||
| 93 | 11276 | AP1GBP1 (AP1 gamma subunit binding protein 1) | 14922 | -1.502 | -0.4651 | No | ||
| 94 | 2524 | FUT2 (fucosyltransferase 2 (secretor status included)) | 15133 | -1.664 | -0.4749 | No | ||
| 95 | 5627 | PROS1 (protein S (alpha)) | 15212 | -1.731 | -0.4781 | No | ||
| 96 | 9159 | PCSK7 (proprotein convertase subtilisin/kexin type 7) | 15325 | -1.811 | -0.4829 | No | ||
| 97 | 682 | BSG (basigin (Ok blood group)) | 15661 | -2.107 | -0.4987 | No | ||
| 98 | 4122 | "MAN2A2 (mannosidase, alpha, class 2A, member 2)" | 15683 | -2.131 | -0.4989 | No | ||
| 99 | 57134 | "MAN1C1 (mannosidase, alpha, class 1C, member 1)" | 15697 | -2.146 | -0.4988 | No | ||
| 100 | 23390 | "ZDHHC17 (zinc finger, DHHC-type containing 17)" | 16024 | -2.532 | -0.5139 | No | ||
| 101 | 540 | "ATP7B (ATPase, Cu++ transporting, beta polypeptide)" | 16396 | -3.056 | -0.5311 | No | ||
| 102 | 23315 | "SLC9A8 (solute carrier family 9 (sodium/hydrogen exchanger), member 8)" | 16766 | -3.718 | -0.5480 | No | ||
| 103 | 11046 | "SLC35D2 (solute carrier family 35, member D2)" | 16855 | -3.878 | -0.5508 | No | ||
| 104 | 8869 | "ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)" | 16915 | -4.025 | -0.5522 | No | ||
| 105 | 8729 | GBF1 (golgi-specific brefeldin A resistance factor 1) | 16921 | -4.035 | -0.5509 | No | ||
| 106 | 26119 | LDLRAP1 (low density lipoprotein receptor adaptor protein 1) | 16987 | -4.212 | -0.5525 | No | ||
| 107 | 9583 | ENTPD4 (ectonucleoside triphosphate diphosphohydrolase 4) | 17067 | -4.432 | -0.5547 | No | ||
| 108 | 2131 | EXT1 (exostoses (multiple) 1) | 17217 | -4.784 | -0.5602 | No | ||
| 109 | 6484 | "ST3GAL4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4)" | 17316 | -5.032 | -0.5631 | No | ||
| 110 | 51226 | "COPZ2 (coatomer protein complex, subunit zeta 2)" | 17410 | -5.319 | -0.5657 | No | ||
| 111 | 8674 | VAMP4 (vesicle-associated membrane protein 4) | 17627 | -6.114 | -0.5740 | No | ||
| 112 | 259230 | SGMS1 (sphingomyelin synthase 1) | 17680 | -6.357 | -0.5741 | No | ||
| 113 | 5045 | FURIN (furin (paired basic amino acid cleaving enzyme)) | 17734 | -6.604 | -0.5742 | No | ||
| 114 | 10053 | "AP1M2 (adaptor-related protein complex 1, mu 2 subunit)" | 17870 | -7.186 | -0.5781 | No | ||
| 115 | 23443 | "SLC35A3 (solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3)" | 17942 | -7.622 | -0.5786 | No | ||
| 116 | 55062 | "WIPI1 (WD repeat domain, phosphoinositide interacting 1)" | 17994 | -7.878 | -0.5781 | No | ||
| 117 | 55343 | "SLC35C1 (solute carrier family 35, member C1)" | 18000 | -7.911 | -0.5753 | No | ||
| 118 | 55501 | CHST12 (carbohydrate (chondroitin 4) sulfotransferase 12) | 18065 | -8.250 | -0.5753 | No | ||
| 119 | 4245 | "MGAT1 (mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase)" | 18149 | -8.754 | -0.5760 | No | ||
| 120 | 10228 | STX6 (syntaxin 6) | 18157 | -8.788 | -0.5729 | No | ||
| 121 | 373 | TRIM23 (tripartite motif-containing 23) | 18300 | -9.614 | -0.5762 | No | ||
| 122 | 9980 | DOPEY2 (dopey family member 2) | 18370 | -10.069 | -0.5757 | No | ||
| 123 | 11320 | "MGAT4A (mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A)" | 18544 | -11.464 | -0.5799 | No | ||
| 124 | 7903 | "ST8SIA4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4)" | 18749 | -13.590 | -0.5847 | No | ||
| 125 | 2802 | "GOLGA3 (golgi autoantigen, golgin subfamily a, 3)" | 18903 | -15.393 | -0.5863 | No | ||
| 126 | 9914 | "ATP2C2 (ATPase, Ca++ transporting, type 2C, member 2)" | 19048 | -17.814 | -0.5866 | Yes | ||
| 127 | 3382 | "ICA1 (islet cell autoantigen 1, 69kDa)" | 19049 | -17.825 | -0.5796 | Yes | ||
| 128 | 27236 | ARFIP1 (ADP-ribosylation factor interacting protein 1) | 19054 | -17.923 | -0.5729 | Yes | ||
| 129 | 5768 | QSOX1 (quiescin Q6 sulfhydryl oxidase 1) | 19195 | -20.482 | -0.5719 | Yes | ||
| 130 | 3134 | "HLA-F (major histocompatibility complex, class I, F)" | 19233 | -21.099 | -0.5655 | Yes | ||
| 131 | 375 | ARF1 (ADP-ribosylation factor 1) | 19469 | -27.515 | -0.5665 | Yes | ||
| 132 | 3133 | "HLA-E (major histocompatibility complex, class I, E)" | 19478 | -27.797 | -0.5561 | Yes | ||
| 133 | 9276 | "COPB2 (coatomer protein complex, subunit beta 2 (beta prime))" | 19491 | -28.306 | -0.5458 | Yes | ||
| 134 | 372 | ARCN1 (archain 1) | 19503 | -28.429 | -0.5353 | Yes | ||
| 135 | 11282 | "MGAT4B (mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B)" | 19520 | -28.872 | -0.5249 | Yes | ||
| 136 | 6480 | "ST6GAL1 (ST6 beta-galactosamide alpha-2,6-sialyltranferase 1)" | 19564 | -30.376 | -0.5152 | Yes | ||
| 137 | 2530 | "FUT8 (fucosyltransferase 8 (alpha (1,6) fucosyltransferase))" | 19607 | -31.965 | -0.5049 | Yes | ||
| 138 | 10559 | "SLC35A1 (solute carrier family 35 (CMP-sialic acid transporter), member A1)" | 19693 | -36.496 | -0.4950 | Yes | ||
| 139 | 6892 | TAPBP (TAP binding protein (tapasin)) | 19699 | -36.965 | -0.4809 | Yes | ||
| 140 | 164 | "AP1G1 (adaptor-related protein complex 1, gamma 1 subunit)" | 19805 | -42.696 | -0.4695 | Yes | ||
| 141 | 64285 | RHBDF1 (rhomboid 5 homolog 1 (Drosophila)) | 19826 | -44.436 | -0.4533 | Yes | ||
| 142 | 3135 | "HLA-G (major histocompatibility complex, class I, G)" | 19863 | -47.478 | -0.4367 | Yes | ||
| 143 | 1314 | "COPA (coatomer protein complex, subunit alpha)" | 19938 | -55.406 | -0.4189 | Yes | ||
| 144 | 54812 | AFTPH (aftiphilin) | 19968 | -58.680 | -0.3975 | Yes | ||
| 145 | 1201 | "CLN3 (ceroid-lipofuscinosis, neuronal 3)" | 19985 | -61.160 | -0.3746 | Yes | ||
| 146 | 3105 | "HLA-A (major histocompatibility complex, class I, A)" | 20027 | -65.132 | -0.3514 | Yes | ||
| 147 | 3106 | "HLA-B (major histocompatibility complex, class I, B)" | 20100 | -78.491 | -0.3245 | Yes | ||
| 148 | 3107 | "HLA-C (major histocompatibility complex, class I, C)" | 20243 | -142.867 | -0.2762 | Yes | ||
| 149 | 11345 | GABARAPL2 (GABA(A) receptor-associated protein-like 2) | 20300 | -214.017 | -0.1959 | Yes | ||
| 150 | 567 | B2M (beta-2-microglobulin) | 20305 | -220.982 | -0.1104 | Yes | ||
| 151 | 2778 | GNAS (GNAS complex locus) | 20315 | -287.233 | 0.0005 | Yes |
