Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classtreated
GeneSetKEGG|HSA03008
Enrichment Score (ES)0.83452326
Normalized Enrichment Score (NES)1.8097132
Nominal p-value0.0
FDR q-value0.0018137803
FWER p-Value0.0020
Table: GSEA Results Summary



Fig 1: Enrichment plot: KEGG|HSA03008   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
155651"NOLA2 (nucleolar protein family A, member 2 (H/ACA small nucleolar RNPs))"16288.7670.0991Yes
25901"RAN (RAN, member RAS oncogene family)"27250.1270.1850Yes
351602NOP5/NOP58 (nucleolar protein NOP5/NOP58)106143.5740.2308Yes
44809NHP2L1 (NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae))162113.7000.2674Yes
51736"DKC1 (dyskeratosis congenita 1, dyskerin)"177108.9490.3044Yes
651096"UTP18 (UTP18, small subunit (SSU) processome component, homolog (yeast))"178108.8540.3420Yes
792856"IMP4 (IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast))"25592.3090.3702Yes
884916"CIRH1A (cirrhosis, autosomal recessive 1A (cirhin))"29885.9730.3979Yes
93692EIF6 (eukaryotic translation initiation factor 6)33880.9580.4239Yes
102091FBL (fibrillarin)34979.1650.4508Yes
1110528NOL5A (nucleolar protein 5A (56kDa with KKE/D repeat))35378.8900.4779Yes
127514"XPO1 (exportin 1 (CRM1 homolog, yeast))"53959.4620.4893Yes
1329107NXT1 (NTF2-like export factor 1)57257.2450.5076Yes
1410799RPP40 (ribonuclease P/MRP 40kDa subunit)65451.9120.5215Yes
1555272"IMP3 (IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast))"68350.4300.5376Yes
1610885WDR3 (WD repeat domain 3)69849.5080.5540Yes
1710248"POP7 (processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae))"69949.4750.5711Yes
1823560GTPBP4 (GTP binding protein 4)72248.1680.5867Yes
191460"CSNK2B (casein kinase 2, beta polypeptide)"74447.3390.6020Yes
2055127HEATR1 (HEAT repeat containing 1)79844.9500.6149Yes
2155505"NOLA3 (nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs))"82643.5880.6287Yes
2255341LSG1 (large subunit GTPase 1 homolog (S. cerevisiae))85642.3700.6419Yes
2310813"UTP14A (UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast))"88041.2740.6550Yes
2455781RIOK2 (RIO kinase 2 (yeast))92239.9560.6668Yes
2584128WDR75 (WD repeat domain 75)94738.5920.6790Yes
2655131RBM28 (RNA binding motif protein 28)96038.1810.6916Yes
279790"BMS1 (BMS1 homolog, ribosome assembly protein (yeast))"101436.4930.7016Yes
2855226NAT10 (N-acetyltransferase 10)110133.7290.7090Yes
2910171RCL1 (RNA terminal phosphate cyclase-like 1)110933.4790.7202Yes
3051119SBDS (Shwachman-Bodian-Diamond syndrome)112033.2040.7312Yes
3129889GNL2 (guanine nucleotide binding protein-like 2 (nucleolar))113732.7450.7417Yes
3228987NOB1 (NIN1/RPN12 binding protein 1 homolog (S. cerevisiae))116632.0010.7514Yes
3351367"POP5 (processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae))"120031.1640.7606Yes
3410199MPHOSPH10 (M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein))128529.3800.7666Yes
3526354GNL3 (guanine nucleotide binding protein-like 3 (nucleolar))134327.9140.7734Yes
3654913RPP25 (ribonuclease P/MRP 25kDa subunit)143426.4820.7781Yes
3723160WDR43 (WD repeat domain 43)145826.0960.7860Yes
386880"TAF9 (TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa)"150125.3500.7927Yes
3951077FCF1 (FCF1 small subunit (SSU) processome component homolog (S. cerevisiae))176521.4730.7871Yes
4027341RRP7A (ribosomal RNA processing 7 homolog A (S. cerevisiae))181720.8260.7918Yes
415822PWP2 (PWP2 periodic tryptophan protein homolog (yeast))188620.0990.7954Yes
426949TCOF1 (Treacher Collins-Franceschetti syndrome 1)190519.8720.8014Yes
4355813"UTP6 (UTP6, small subunit (SSU) processome component, homolog (yeast))"191019.8600.8081Yes
4410557RPP38 (ribonuclease P/MRP 38kDa subunit)202918.4910.8086Yes
4583732RIOK1 (RIO kinase 1 (yeast))205218.3020.8139Yes
4684135"UTP15 (UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae))"208918.0200.8183Yes
471457"CSNK2A1 (casein kinase 2, alpha 1 polypeptide)"213617.6080.8221Yes
4854552GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like)214617.5160.8277Yes
49134430WDR36 (WD repeat domain 36)218417.2550.8319Yes
5010607TBL3 (transducin (beta)-like 3)224816.6400.8345Yes
5154433"NOLA1 (nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs))"260413.4360.8216No
5229102"RNASEN (ribonuclease type III, nuclear)"267412.9960.8227No
5310482NXF1 (nuclear RNA export factor 1)281112.1450.8202No
5455916NXT2 (nuclear transport factor 2-like export factor 2)301010.9770.8142No
5565083NOL6 (nucleolar protein family 6 (RNA-associated))31929.9990.8087No
5654464XRN1 (5'-3' exoribonuclease 1)32639.6670.8086No
5710775"POP4 (processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae))"34009.1540.8051No
581459"CSNK2A2 (casein kinase 2, alpha prime polypeptide)"35328.6380.8016No
5910940"POP1 (processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae))"35708.4680.8027No
6010556RPP30 (ribonuclease P/MRP 30kDa subunit)36608.1380.8011No
6123195"MDN1 (MDN1, midasin homolog (yeast))"38227.4210.7957No
62166378SPATA5 (spermatogenesis associated 5)38927.1170.7948No
63138716C9orf23 (chromosome 9 open reading frame 23)39277.0060.7955No
649724"UTP14C (UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast))"43355.6710.7774No
6525996"REXO2 (REX2, RNA exonuclease 2 homolog (S. cerevisiae))"56272.8780.7146No
6656001NXF2 (nuclear RNA export factor 2)65821.6920.6681No
6755998NXF5 (nuclear RNA export factor 5)80430.7130.5963No
6856000NXF3 (nuclear RNA export factor 3)86880.4820.5646No
6957455"REXO1 (REX1, RNA exonuclease 1 homolog (S. cerevisiae))"14805-1.4240.2631No
70254958"REXO1L1 (REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1)"15101-1.6370.2491No
7122803XRN2 (5'-3' exoribonuclease 2)15213-1.7320.2443No
7279631EFTUD1 (elongation factor Tu GTP binding domain containing 1)16673-3.5480.1734No
7351068NMD3 (NMD3 homolog (S. cerevisiae))18108-8.4760.1056No
744931NVL (nuclear VCP-like)18502-11.1400.0900No
Table: GSEA details [plain text format]



Fig 2: KEGG|HSA03008   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KEGG|HSA03008: Random ES distribution   
Gene set null distribution of ES for KEGG|HSA03008