Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | GO|GO:0090316 |
Enrichment Score (ES) | -0.708263 |
Normalized Enrichment Score (NES) | -1.584387 |
Nominal p-value | 0.008264462 |
FDR q-value | 0.29557875 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 999 | "CDH1 (cadherin 1, type 1, E-cadherin (epithelial))" | 597 | 55.288 | 0.0449 | No | ||
2 | 657 | "BMPR1A (bone morphogenetic protein receptor, type IA)" | 2168 | 17.378 | -0.0091 | No | ||
3 | 8877 | SPHK1 (sphingosine kinase 1) | 2474 | 14.588 | -0.0046 | No | ||
4 | 11030 | RBPMS (RNA binding protein with multiple splicing) | 3232 | 9.780 | -0.0287 | No | ||
5 | 2010 | EMD (emerin) | 3549 | 8.598 | -0.0327 | No | ||
6 | 7040 | "TGFB1 (transforming growth factor, beta 1)" | 3665 | 8.104 | -0.0275 | No | ||
7 | 1956 | "EGFR (epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian))" | 5292 | 3.407 | -0.1031 | No | ||
8 | 7545 | "ZIC1 (Zic family member 1 (odd-paired homolog, Drosophila))" | 6735 | 1.562 | -0.1721 | No | ||
9 | 3479 | IGF1 (insulin-like growth factor 1 (somatomedin C)) | 7098 | 1.270 | -0.1882 | No | ||
10 | 340061 | TMEM173 (transmembrane protein 173) | 7361 | 1.090 | -0.1997 | No | ||
11 | 8740 | "TNFSF14 (tumor necrosis factor (ligand) superfamily, member 14)" | 7733 | 0.873 | -0.2168 | No | ||
12 | 2932 | GSK3B (glycogen synthase kinase 3 beta) | 8018 | 0.725 | -0.2298 | No | ||
13 | 163882 | C1orf71 (chromosome 1 open reading frame 71) | 8114 | 0.686 | -0.2336 | No | ||
14 | 7097 | TLR2 (toll-like receptor 2) | 8386 | 0.583 | -0.2462 | No | ||
15 | 939 | CD27 (CD27 molecule) | 9453 | 0.264 | -0.2984 | No | ||
16 | 3569 | "IL6 (interleukin 6 (interferon, beta 2))" | 9770 | 0.188 | -0.3137 | No | ||
17 | 51284 | TLR7 (toll-like receptor 7) | 10492 | 0.016 | -0.3492 | No | ||
18 | 4089 | SMAD4 (SMAD family member 4) | 10664 | -0.017 | -0.3576 | No | ||
19 | 3593 | "IL12B (interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40))" | 11374 | -0.185 | -0.3923 | No | ||
20 | 7098 | TLR3 (toll-like receptor 3) | 11911 | -0.304 | -0.4184 | No | ||
21 | 3553 | "IL1B (interleukin 1, beta)" | 11912 | -0.304 | -0.4179 | No | ||
22 | 1950 | EGF (epidermal growth factor (beta-urogastrone)) | 12439 | -0.441 | -0.4433 | No | ||
23 | 7124 | "TNF (tumor necrosis factor (TNF superfamily, member 2))" | 12777 | -0.537 | -0.4592 | No | ||
24 | 6363 | CCL19 (chemokine (C-C motif) ligand 19) | 12834 | -0.556 | -0.4612 | No | ||
25 | 5460 | POU5F1 (POU class 5 homeobox 1) | 13341 | -0.718 | -0.4852 | No | ||
26 | 7099 | TLR4 (toll-like receptor 4) | 14032 | -1.010 | -0.5178 | No | ||
27 | 90070 | LACRT (lacritin) | 15089 | -1.628 | -0.5677 | No | ||
28 | 54106 | TLR9 (toll-like receptor 9) | 15160 | -1.682 | -0.5689 | No | ||
29 | 91662 | "NLRP12 (NLR family, pyrin domain containing 12)" | 15825 | -2.282 | -0.5986 | No | ||
30 | 7046 | "TGFBR1 (transforming growth factor, beta receptor 1)" | 18051 | -8.147 | -0.6973 | Yes | ||
31 | 7043 | "TGFB3 (transforming growth factor, beta 3)" | 18102 | -8.466 | -0.6884 | Yes | ||
32 | 7205 | TRIP6 (thyroid hormone receptor interactor 6) | 18141 | -8.698 | -0.6786 | Yes | ||
33 | 652 | BMP4 (bone morphogenetic protein 4) | 18378 | -10.143 | -0.6766 | Yes | ||
34 | 4088 | SMAD3 (SMAD family member 3) | 18573 | -11.772 | -0.6703 | Yes | ||
35 | 51561 | "IL23A (interleukin 23, alpha subunit p19)" | 19029 | -17.353 | -0.6694 | Yes | ||
36 | 2316 | "FLNA (filamin A, alpha (actin binding protein 280))" | 19138 | -19.560 | -0.6484 | Yes | ||
37 | 23586 | DDX58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58) | 19385 | -25.182 | -0.6267 | Yes | ||
38 | 51366 | UBR5 (ubiquitin protein ligase E3 component n-recognin 5) | 19390 | -25.318 | -0.5928 | Yes | ||
39 | 387 | "RHOA (ras homolog gene family, member A)" | 19574 | -30.675 | -0.5606 | Yes | ||
40 | 57506 | VISA (virus-induced signaling adapter) | 19622 | -32.677 | -0.5190 | Yes | ||
41 | 6934 | "TCF7L2 (transcription factor 7-like 2 (T-cell specific, HMG-box))" | 19726 | -38.340 | -0.4725 | Yes | ||
42 | 3728 | JUP (junction plakoglobin) | 19987 | -61.273 | -0.4030 | Yes | ||
43 | 25805 | BAMBI (BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)) | 20317 | -312.036 | 0.0004 | Yes |