Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | GO|GO:0030879 |
Enrichment Score (ES) | -0.7080405 |
Normalized Enrichment Score (NES) | -1.5618479 |
Nominal p-value | 0.011331445 |
FDR q-value | 0.3284926 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 3717 | JAK2 (Janus kinase 2 (a protein tyrosine kinase)) | 1526 | 24.947 | -0.0341 | No | ||
2 | 80139 | ZNF703 (zinc finger protein 703) | 2033 | 18.476 | -0.0286 | No | ||
3 | 5618 | PRLR (prolactin receptor) | 2254 | 16.576 | -0.0121 | No | ||
4 | 675 | "BRCA2 (breast cancer 2, early onset)" | 2400 | 15.152 | 0.0057 | No | ||
5 | 10522 | DEAF1 (deformed epidermal autoregulatory factor 1 (Drosophila)) | 2935 | 11.406 | -0.0018 | No | ||
6 | 6091 | "ROBO1 (roundabout, axon guidance receptor, homolog 1 (Drosophila))" | 2962 | 11.226 | 0.0154 | No | ||
7 | 857 | "CAV1 (caveolin 1, caveolae protein, 22kDa)" | 3406 | 9.137 | 0.0087 | No | ||
8 | 1969 | EPHA2 (EPH receptor A2) | 5067 | 3.890 | -0.0668 | No | ||
9 | 23513 | SCRIB (scribbled homolog (Drosophila)) | 5093 | 3.843 | -0.0616 | No | ||
10 | 137964 | "AGPAT6 (1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta))" | 5106 | 3.805 | -0.0560 | No | ||
11 | 3084 | NRG1 (neuregulin 1) | 5559 | 2.980 | -0.0733 | No | ||
12 | 54361 | "WNT4 (wingless-type MMTV integration site family, member 4)" | 5623 | 2.881 | -0.0717 | No | ||
13 | 2263 | FGFR2 (fibroblast growth factor receptor 2) | 6001 | 2.374 | -0.0864 | No | ||
14 | 7473 | "WNT3 (wingless-type MMTV integration site family, member 3)" | 6468 | 1.804 | -0.1064 | No | ||
15 | 8862 | APLN (apelin) | 7696 | 0.891 | -0.1654 | No | ||
16 | 6926 | TBX3 (T-box 3) | 8948 | 0.401 | -0.2264 | No | ||
17 | 5021 | OXTR (oxytocin receptor) | 9324 | 0.298 | -0.2444 | No | ||
18 | 7477 | "WNT7B (wingless-type MMTV integration site family, member 7B)" | 9405 | 0.278 | -0.2478 | No | ||
19 | 6997 | TDGF1 (teratocarcinoma-derived growth factor 1) | 9475 | 0.260 | -0.2508 | No | ||
20 | 2255 | FGF10 (fibroblast growth factor 10) | 9561 | 0.239 | -0.2546 | No | ||
21 | 27023 | FOXB1 (forkhead box B1) | 10048 | 0.122 | -0.2784 | No | ||
22 | 7474 | "WNT5A (wingless-type MMTV integration site family, member 5A)" | 10164 | 0.093 | -0.2839 | No | ||
23 | 2487 | FRZB (frizzled-related protein) | 10360 | 0.047 | -0.2934 | No | ||
24 | 4040 | LRP6 (low density lipoprotein receptor-related protein 6) | 10453 | 0.025 | -0.2979 | No | ||
25 | 4041 | LRP5 (low density lipoprotein receptor-related protein 5) | 10489 | 0.016 | -0.2996 | No | ||
26 | 51176 | LEF1 (lymphoid enhancer-binding factor 1) | 12631 | -0.495 | -0.4043 | No | ||
27 | 6424 | SFRP4 (secreted frizzled-related protein 4) | 12681 | -0.506 | -0.4059 | No | ||
28 | 7472 | WNT2 (wingless-type MMTV integration site family member 2) | 12752 | -0.529 | -0.4085 | No | ||
29 | 2876 | GPX1 (glutathione peroxidase 1) | 13143 | -0.650 | -0.4266 | No | ||
30 | 4855 | NOTCH4 (Notch homolog 4 (Drosophila)) | 13834 | -0.914 | -0.4591 | No | ||
31 | 2736 | GLI2 (GLI-Kruppel family member GLI2) | 14561 | -1.273 | -0.4928 | No | ||
32 | 3664 | IRF6 (interferon regulatory factor 6) | 17986 | -7.831 | -0.6487 | No | ||
33 | 7043 | "TGFB3 (transforming growth factor, beta 3)" | 18102 | -8.466 | -0.6404 | No | ||
34 | 1999 | "ELF3 (E74-like factor 3 (ets domain transcription factor, epithelial-specific ))" | 19067 | -18.273 | -0.6578 | Yes | ||
35 | 2064 | "ERBB2 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian))" | 20088 | -74.815 | -0.5847 | Yes | ||
36 | 3398 | "ID2 (inhibitor of DNA binding 2, dominant negative helix-loop-helix protein)" | 20185 | -106.279 | -0.4143 | Yes | ||
37 | 2625 | GATA3 (GATA binding protein 3) | 20312 | -255.499 | 0.0006 | Yes |