Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | GO|GO:0009074 |
Enrichment Score (ES) | -0.8805106 |
Normalized Enrichment Score (NES) | -1.7030746 |
Nominal p-value | 0.0 |
FDR q-value | 0.12256486 |
FWER p-Value | 0.899 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 3081 | "HGD (homogentisate 1,2-dioxygenase (homogentisate oxidase))" | 5666 | 2.813 | -0.2721 | No | ||
2 | 5092 | PCBD1 (pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha) | 5852 | 2.549 | -0.2750 | No | ||
3 | 51166 | AADAT (aminoadipate aminotransferase) | 6430 | 1.850 | -0.2988 | No | ||
4 | 6898 | TAT (tyrosine aminotransferase) | 7093 | 1.273 | -0.3283 | No | ||
5 | 56267 | CCBL2 (cysteine conjugate-beta lyase 2) | 7121 | 1.253 | -0.3266 | No | ||
6 | 883 | "CCBL1 (cysteine conjugate-beta lyase, cytoplasmic)" | 7903 | 0.782 | -0.3631 | No | ||
7 | 169355 | "INDOL1 (indoleamine-pyrrole 2,3 dioxygenase-like 1)" | 8133 | 0.681 | -0.3727 | No | ||
8 | 6999 | "TDO2 (tryptophan 2,3-dioxygenase)" | 9210 | 0.331 | -0.4249 | No | ||
9 | 130013 | ACMSD (aminocarboxymuconate semialdehyde decarboxylase) | 9401 | 0.279 | -0.4336 | No | ||
10 | 2184 | FAH (fumarylacetoacetate hydrolase (fumarylacetoacetase)) | 10036 | 0.125 | -0.4645 | No | ||
11 | 5053 | PAH (phenylalanine hydroxylase) | 10493 | 0.016 | -0.4869 | No | ||
12 | 3242 | HPD (4-hydroxyphenylpyruvate dioxygenase) | 12417 | -0.433 | -0.5805 | No | ||
13 | 3620 | "INDO (indoleamine-pyrrole 2,3 dioxygenase)" | 13182 | -0.662 | -0.6165 | No | ||
14 | 125061 | AFMID (arylformamidase) | 14774 | -1.408 | -0.6914 | No | ||
15 | 23498 | "HAAO (3-hydroxyanthranilate 3,4-dioxygenase)" | 14801 | -1.422 | -0.6892 | No | ||
16 | 5860 | QDPR (quinoid dihydropteridine reductase) | 18687 | -12.896 | -0.8489 | Yes | ||
17 | 8564 | KMO (kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)) | 19162 | -19.956 | -0.8232 | Yes | ||
18 | 2954 | GSTZ1 (glutathione transferase zeta 1) | 19335 | -23.767 | -0.7733 | Yes | ||
19 | 8942 | KYNU (kynureninase (L-kynurenine hydrolase)) | 20320 | -334.884 | 0.0002 | Yes |