Datasetexpression_12hrs.Phenotype.cls
#treated_versus_cont.Phenotype.cls
#treated_versus_cont_repos
PhenotypePhenotype.cls#treated_versus_cont_repos
Upregulated in classtreated
GeneSetREACTOME|REACT_1366.1
Enrichment Score (ES)0.7460373
Normalized Enrichment Score (NES)1.686816
Nominal p-value0.0
FDR q-value0.01608514
FWER p-Value0.327
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME|REACT_1366.1   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
16432"SFRS7 (splicing factor, arginine/serine-rich 7, 35kDa)"38213.9760.0661Yes
26635SNRPE (small nuclear ribonucleoprotein polypeptide E)43207.4330.1317Yes
36636SNRPF (small nuclear ribonucleoprotein polypeptide F)93154.3880.1783Yes
46426"SFRS1 (splicing factor, arginine/serine-rich 1)"119133.0170.2193Yes
510189THOC4 (THO complex 4)158117.0780.2546Yes
66634SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide 18kDa)196103.4340.2856Yes
79939RBM8A (RNA binding motif protein 8A)201102.6130.3180Yes
85431"POLR2B (polymerase (RNA) II (DNA directed) polypeptide B, 140kDa)"24893.7050.3455Yes
96427"SFRS2 (splicing factor, arginine/serine-rich 2)"27390.1070.3729Yes
106428"SFRS3 (splicing factor, arginine/serine-rich 3)"30285.6640.3987Yes
112966"GTF2H2 (general transcription factor IIH, polypeptide 2, 44kDa)"33780.9800.4228Yes
126921"TCEB1 (transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C))"37775.3770.4448Yes
135436POLR2G (polymerase (RNA) II (DNA directed) polypeptide G)43967.7680.4633Yes
1411198SUPT16H (suppressor of Ty 16 homolog (S. cerevisiae))48463.4690.4812Yes
157307U2AF1 (U2 small nuclear RNA auxiliary factor 1)50961.5550.4996Yes
165435POLR2F (polymerase (RNA) II (DNA directed) polypeptide F)53160.3460.5177Yes
17902CCNH (cyclin H)53659.5430.5364Yes
185441"POLR2L (polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa)"65551.8330.5471Yes
196628SNRPB (small nuclear ribonucleoprotein polypeptides B and B1)69749.7170.5608Yes
206923"TCEB2 (transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B))"70748.6990.5758Yes
211479"CSTF3 (cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa)"76746.2720.5876Yes
226882"TAF11 (TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa)"85442.4290.5968Yes
234686"NCBP1 (nuclear cap binding protein subunit 1, 80kDa)"86042.2660.6100Yes
247884SLBP (stem-loop binding protein)96637.9850.6169Yes
2522916"NCBP2 (nuclear cap binding protein subunit 2, 20kDa)"98637.5280.6279Yes
264116"MAGOH (mago-nashi homolog, proliferation-associated (Drosophila))"100936.6190.6384Yes
279295"SFRS11 (splicing factor, arginine/serine-rich 11)"104235.3880.6480Yes
2884967"LSM10 (LSM10, U7 small nuclear RNA associated)"106534.7190.6580Yes
2910921"RNPS1 (RNA binding protein S1, serine-rich domain)"110733.5360.6666Yes
3011338U2AF2 (U2 small nuclear RNA auxiliary factor 2)111233.3720.6770Yes
315438"POLR2I (polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa)"115732.2490.6851Yes
326878"TAF6 (TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa)"122330.5550.6916Yes
332967"GTF2H3 (general transcription factor IIH, polypeptide 3, 34kDa)"127329.6250.6985Yes
345434"POLR2E (polymerase (RNA) II (DNA directed) polypeptide E, 25kDa)"132828.2680.7048Yes
356880"TAF9 (TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa)"150125.3500.7044Yes
366917"TCEA1 (transcription elongation factor A (SII), 1)"163523.4060.7052Yes
372957"GTF2A1 (general transcription factor IIA, 1, 19/37kDa)"167922.7080.7103Yes
385433POLR2D (polymerase (RNA) II (DNA directed) polypeptide D)174721.7110.7139Yes
396874"TAF4 (TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa)"175921.5090.7202Yes
405432"POLR2C (polymerase (RNA) II (DNA directed) polypeptide C, 33kDa)"177221.3890.7264Yes
4165109UPF3B (UPF3 regulator of nonsense transcripts homolog B (yeast))177821.3410.7329Yes
426749SSRP1 (structure specific recognition protein 1)194319.5770.7310Yes
436429"SFRS4 (splicing factor, arginine/serine-rich 4)"197019.1040.7358Yes
442963"GTF2F2 (general transcription factor IIF, polypeptide 2, 30kDa)"205618.2640.7374Yes
4551362CDC40 (cell division cycle 40 homolog (S. cerevisiae))209817.9420.7411Yes
466431"SFRS6 (splicing factor, arginine/serine-rich 6)"211317.8000.7460Yes
47905CCNT2 (cyclin T2)242914.8800.7352No
486881"TAF10 (TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa)"268112.9630.7269No
4929894"CPSF1 (cleavage and polyadenylation specific factor 1, 160kDa)"272012.7110.7291No
502961"GTF2E2 (general transcription factor IIE, polypeptide 2, beta 34kDa)"273012.6400.7326No
516877"TAF5 (TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa)"292111.5050.7269No
526827SUPT4H1 (suppressor of Ty 4 homolog 1 (S. cerevisiae))305810.6690.7235No
537936RDBP (RD RNA binding protein)308610.5150.7255No
5411051NUDT21 (nudix (nucleoside diphosphate linked moiety X)-type motif 21)313910.2330.7262No
556875"TAF4B (TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa)"32169.8710.7256No
5651692"CPSF3 (cleavage and polyadenylation specific factor 3, 73kDa)"32999.5330.7246No
579150"CTDP1 (CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1)"33039.5180.7275No
582968"GTF2H4 (general transcription factor IIH, polypeptide 4, 52kDa)"34169.1030.7248No
5979869"FLJ12529 (pre-mRNA cleavage factor I, 59 kDa subunit)"34828.7990.7244No
6010250SRRM1 (serine/arginine repetitive matrix 1)34848.7950.7271No
616872"TAF1 (TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa)"35108.7050.7287No
624331"MNAT1 (menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis))"35838.4170.7278No
635430"POLR2A (polymerase (RNA) II (DNA directed) polypeptide A, 220kDa)"36268.2310.7283No
6410914PAPOLA (poly(A) polymerase alpha)38757.1870.7183No
65904CCNT1 (cyclin T1)40466.6530.7120No
6625888ZNF473 (zinc finger protein 473)44095.4670.6959No
675437POLR2H (polymerase (RNA) II (DNA directed) polypeptide H)45965.0000.6883No
686908TBP (TATA box binding protein)46904.7390.6852No
692068"ERCC2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)"51593.7020.6632No
701478"CSTF2 (cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa)"54943.0740.6477No
7110978"CLP1 (CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae))"57832.6370.6343No
722071"ERCC3 (excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing))"59442.4390.6271No
73134353"LSM11 (LSM11, U7 small nuclear RNA associated)"60242.3460.6240No
742965"GTF2H1 (general transcription factor IIH, polypeptide 1, 62kDa)"61552.1630.6182No
757469WHSC2 (Wolf-Hirschhorn syndrome candidate 2)62782.0210.6128No
765440"POLR2K (polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa)"63211.9700.6114No
772962"GTF2F1 (general transcription factor IIF, polypeptide 1, 74kDa)"63881.8940.6087No
788106"PABPN1 (poly(A) binding protein, nuclear 1)"98660.1670.4369No
796924"TCEB3 (transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A))"103190.0590.4146No
801025CDK9 (cyclin-dependent kinase 9)104180.0340.4097No
816884"TAF13 (TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa)"13077-0.6300.2785No
828178ELL (elongation factor RNA polymerase II)14520-1.2540.2076No
832958"GTF2A2 (general transcription factor IIA, 2, 12kDa)"14627-1.3110.2028No
849785DHX38 (DEAH (Asp-Glu-Ala-His) box polypeptide 38)14908-1.4910.1894No
8553981"CPSF2 (cleavage and polyadenylation specific factor 2, 100kDa)"15120-1.6540.1795No
862960"GTF2E1 (general transcription factor IIE, polypeptide 1, alpha 56kDa)"16002-2.5030.1368No
878732RNGTT (RNA guanylyltransferase and 5'-phosphatase)16653-3.4990.1057No
888731RNMT (RNA (guanine-7-) methyltransferase)16887-3.9670.0955No
896883"TAF12 (TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa)"17252-4.8580.0790No
901477"CSTF1 (cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa)"18059-8.1900.0418No
915439"POLR2J (polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa)"18134-8.6610.0409No
922959GTF2B (general transcription factor IIB)18273-9.4290.0370No
938683"SFRS9 (splicing factor, arginine/serine-rich 9)"18964-16.2500.0081No
9425920COBRA1 (cofactor of BRCA1)19016-17.1340.0110No
956637SNRPG (small nuclear ribonucleoprotein polypeptide G)19107-18.9860.0126No
9651585"PCF11 (PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae))"19324-23.5840.0094No
9751497TH1L (TH1-like (Drosophila))19618-32.5680.0053No
981022CDK7 (cyclin-dependent kinase 7)19757-39.6000.0110No
996430"SFRS5 (splicing factor, arginine/serine-rich 5)"19923-53.6360.0199No
Table: GSEA details [plain text format]



Fig 2: REACTOME|REACT_1366.1   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME|REACT_1366.1: Random ES distribution   
Gene set null distribution of ES for REACTOME|REACT_1366.1