Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | GO|GO:0009072 |
Enrichment Score (ES) | -0.85663086 |
Normalized Enrichment Score (NES) | -1.7346128 |
Nominal p-value | 0.0 |
FDR q-value | 0.10061542 |
FWER p-Value | 0.69 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 7054 | TH (tyrosine hydroxylase) | 4374 | 5.542 | -0.2025 | No | ||
2 | 3081 | "HGD (homogentisate 1,2-dioxygenase (homogentisate oxidase))" | 5666 | 2.813 | -0.2595 | No | ||
3 | 5092 | PCBD1 (pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha) | 5852 | 2.549 | -0.2626 | No | ||
4 | 51166 | AADAT (aminoadipate aminotransferase) | 6430 | 1.850 | -0.2867 | No | ||
5 | 6898 | TAT (tyrosine aminotransferase) | 7093 | 1.273 | -0.3163 | No | ||
6 | 56267 | CCBL2 (cysteine conjugate-beta lyase 2) | 7121 | 1.253 | -0.3147 | No | ||
7 | 883 | "CCBL1 (cysteine conjugate-beta lyase, cytoplasmic)" | 7903 | 0.782 | -0.3513 | No | ||
8 | 169355 | "INDOL1 (indoleamine-pyrrole 2,3 dioxygenase-like 1)" | 8133 | 0.681 | -0.3610 | No | ||
9 | 6999 | "TDO2 (tryptophan 2,3-dioxygenase)" | 9210 | 0.331 | -0.4132 | No | ||
10 | 1638 | "DCT (dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2))" | 9306 | 0.303 | -0.4172 | No | ||
11 | 130013 | ACMSD (aminocarboxymuconate semialdehyde decarboxylase) | 9401 | 0.279 | -0.4212 | No | ||
12 | 2184 | FAH (fumarylacetoacetate hydrolase (fumarylacetoacetase)) | 10036 | 0.125 | -0.4521 | No | ||
13 | 5053 | PAH (phenylalanine hydroxylase) | 10493 | 0.016 | -0.4745 | No | ||
14 | 3242 | HPD (4-hydroxyphenylpyruvate dioxygenase) | 12417 | -0.433 | -0.5682 | No | ||
15 | 3620 | "INDO (indoleamine-pyrrole 2,3 dioxygenase)" | 13182 | -0.662 | -0.6043 | No | ||
16 | 125061 | AFMID (arylformamidase) | 14774 | -1.408 | -0.6794 | No | ||
17 | 23498 | "HAAO (3-hydroxyanthranilate 3,4-dioxygenase)" | 14801 | -1.422 | -0.6773 | No | ||
18 | 7299 | TYR (tyrosinase (oculocutaneous albinism IA)) | 15726 | -2.180 | -0.7177 | No | ||
19 | 538 | "ATP7A (ATPase, Cu++ transporting, alpha polypeptide)" | 18547 | -11.483 | -0.8297 | Yes | ||
20 | 5860 | QDPR (quinoid dihydropteridine reductase) | 18687 | -12.896 | -0.8064 | Yes | ||
21 | 8564 | KMO (kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)) | 19162 | -19.956 | -0.7830 | Yes | ||
22 | 2954 | GSTZ1 (glutathione transferase zeta 1) | 19335 | -23.767 | -0.7358 | Yes | ||
23 | 8942 | KYNU (kynureninase (L-kynurenine hydrolase)) | 20320 | -334.884 | 0.0002 | Yes |