Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | cont |
GeneSet | GO|GO:0030855 |
Enrichment Score (ES) | -0.71163964 |
Normalized Enrichment Score (NES) | -1.8266121 |
Nominal p-value | 0.0 |
FDR q-value | 0.0172689 |
FWER p-Value | 0.095 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 6278 | S100A7 (S100 calcium binding protein A7) | 35 | 222.473 | 0.0812 | No | ||
2 | 50604 | IL20 (interleukin 20) | 409 | 71.360 | 0.0894 | No | ||
3 | 1499 | "CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa)" | 480 | 63.932 | 0.1097 | No | ||
4 | 2626 | GATA4 (GATA binding protein 4) | 1841 | 20.572 | 0.0501 | No | ||
5 | 4781 | NFIB (nuclear factor I/B) | 2026 | 18.529 | 0.0480 | No | ||
6 | 80139 | ZNF703 (zinc finger protein 703) | 2033 | 18.476 | 0.0545 | No | ||
7 | 8721 | EDF1 (endothelial differentiation-related factor 1) | 2317 | 15.880 | 0.0465 | No | ||
8 | 429 | ASCL1 (achaete-scute complex homolog 1 (Drosophila)) | 2462 | 14.694 | 0.0448 | No | ||
9 | 8324 | FZD7 (frizzled homolog 7 (Drosophila)) | 3360 | 9.324 | 0.0039 | No | ||
10 | 857 | "CAV1 (caveolin 1, caveolae protein, 22kDa)" | 3406 | 9.137 | 0.0051 | No | ||
11 | 1594 | "CYP27B1 (cytochrome P450, family 27, subfamily B, polypeptide 1)" | 3417 | 9.100 | 0.0080 | No | ||
12 | 3204 | HOXA7 (homeobox A7) | 3782 | 7.590 | -0.0072 | No | ||
13 | 8321 | FZD1 (frizzled homolog 1 (Drosophila)) | 3915 | 7.040 | -0.0111 | No | ||
14 | 3976 | LIF (leukemia inhibitory factor (cholinergic differentiation factor)) | 4579 | 5.039 | -0.0420 | No | ||
15 | 1969 | EPHA2 (EPH receptor A2) | 5067 | 3.890 | -0.0646 | No | ||
16 | 301 | ANXA1 (annexin A1) | 5110 | 3.798 | -0.0653 | No | ||
17 | 6662 | SOX9 (SRY (sex determining region Y)-box 9) | 5204 | 3.599 | -0.0685 | No | ||
18 | 2125 | EVPL (envoplakin) | 5689 | 2.763 | -0.0914 | No | ||
19 | 2150 | F2RL1 (coagulation factor II (thrombin) receptor-like 1) | 5923 | 2.465 | -0.1020 | No | ||
20 | 2263 | FGFR2 (fibroblast growth factor receptor 2) | 6001 | 2.374 | -0.1050 | No | ||
21 | 3850 | KRT3 (keratin 3) | 6219 | 2.098 | -0.1149 | No | ||
22 | 54206 | ERRFI1 (ERBB receptor feedback inhibitor 1) | 6382 | 1.899 | -0.1222 | No | ||
23 | 8456 | FOXN1 (forkhead box N1) | 6577 | 1.695 | -0.1312 | No | ||
24 | 54345 | SOX18 (SRY (sex determining region Y)-box 18) | 6870 | 1.440 | -0.1451 | No | ||
25 | 7053 | "TGM3 (transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase))" | 6997 | 1.347 | -0.1508 | No | ||
26 | 3975 | LHX1 (LIM homeobox 1) | 7692 | 0.892 | -0.1848 | No | ||
27 | 80274 | "SCUBE1 (signal peptide, CUB domain, EGF-like 1)" | 7818 | 0.826 | -0.1907 | No | ||
28 | 3849 | KRT2 (keratin 2) | 7948 | 0.761 | -0.1968 | No | ||
29 | 7380 | UPK3A (uroplakin 3A) | 8321 | 0.605 | -0.2149 | No | ||
30 | 2302 | FOXJ1 (forkhead box J1) | 8394 | 0.581 | -0.2183 | No | ||
31 | 2022 | ENG (endoglin (Osler-Rendu-Weber syndrome 1)) | 8423 | 0.570 | -0.2195 | No | ||
32 | 7480 | "WNT10B (wingless-type MMTV integration site family, member 10B)" | 8508 | 0.540 | -0.2234 | No | ||
33 | 7490 | WT1 (Wilms tumor 1) | 8559 | 0.526 | -0.2257 | No | ||
34 | 247 | "ALOX15B (arachidonate 15-lipoxygenase, type B)" | 8586 | 0.518 | -0.2268 | No | ||
35 | 2312 | FLG (filaggrin) | 8591 | 0.516 | -0.2268 | No | ||
36 | 6299 | SALL1 (sal-like 1 (Drosophila)) | 8649 | 0.497 | -0.2294 | No | ||
37 | 2069 | EREG (epiregulin) | 9156 | 0.344 | -0.2543 | No | ||
38 | 130497 | OSR1 (odd-skipped related 1 (Drosophila)) | 9299 | 0.305 | -0.2612 | No | ||
39 | 7477 | "WNT7B (wingless-type MMTV integration site family, member 7B)" | 9405 | 0.278 | -0.2663 | No | ||
40 | 140628 | GATA5 (GATA binding protein 5) | 9485 | 0.257 | -0.2701 | No | ||
41 | 4014 | LOR (loricrin) | 9541 | 0.244 | -0.2727 | No | ||
42 | 5076 | PAX2 (paired box 2) | 9603 | 0.228 | -0.2757 | No | ||
43 | 7051 | "TGM1 (transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase))" | 9696 | 0.208 | -0.2802 | No | ||
44 | 3458 | "IFNG (interferon, gamma)" | 9835 | 0.174 | -0.2869 | No | ||
45 | 6495 | SIX1 (SIX homeobox 1) | 9891 | 0.159 | -0.2896 | No | ||
46 | 10626 | TRIM16 (tripartite motif-containing 16) | 9953 | 0.146 | -0.2925 | No | ||
47 | 27023 | FOXB1 (forkhead box B1) | 10048 | 0.122 | -0.2971 | No | ||
48 | 7474 | "WNT5A (wingless-type MMTV integration site family, member 5A)" | 10164 | 0.093 | -0.3028 | No | ||
49 | 3851 | KRT4 (keratin 4) | 10511 | 0.011 | -0.3199 | No | ||
50 | 7484 | "WNT9B (wingless-type MMTV integration site family, member 9B)" | 11179 | -0.139 | -0.3528 | No | ||
51 | 64321 | SOX17 (SRY (sex determining region Y)-box 17) | 11243 | -0.153 | -0.3559 | No | ||
52 | 3171 | FOXA3 (forkhead box A3) | 11323 | -0.170 | -0.3597 | No | ||
53 | 11005 | "SPINK5 (serine peptidase inhibitor, Kazal type 5)" | 11423 | -0.197 | -0.3646 | No | ||
54 | 3713 | IVL (involucrin) | 11768 | -0.274 | -0.3815 | No | ||
55 | 8796 | SCEL (sciellin) | 11915 | -0.304 | -0.3886 | No | ||
56 | 5468 | PPARG (peroxisome proliferator-activated receptor gamma) | 12768 | -0.534 | -0.4305 | No | ||
57 | 51458 | "RHCG (Rh family, C glycoprotein)" | 12920 | -0.582 | -0.4378 | No | ||
58 | 7348 | UPK1B (uroplakin 1B) | 13074 | -0.630 | -0.4451 | No | ||
59 | 51384 | "WNT16 (wingless-type MMTV integration site family, member 16)" | 13231 | -0.676 | -0.4526 | No | ||
60 | 6698 | SPRR1A (small proline-rich protein 1A) | 13258 | -0.686 | -0.4536 | No | ||
61 | 3170 | FOXA2 (forkhead box A2) | 13351 | -0.723 | -0.4579 | No | ||
62 | 6707 | SPRR3 (small proline-rich protein 3) | 13692 | -0.852 | -0.4744 | No | ||
63 | 4855 | NOTCH4 (Notch homolog 4 (Drosophila)) | 13834 | -0.914 | -0.4810 | No | ||
64 | 1041 | CDSN (corneodesmosin) | 13873 | -0.934 | -0.4825 | No | ||
65 | 7476 | "WNT7A (wingless-type MMTV integration site family, member 7A)" | 13938 | -0.966 | -0.4853 | No | ||
66 | 6699 | SPRR1B (small proline-rich protein 1B (cornifin)) | 14030 | -1.009 | -0.4895 | No | ||
67 | 1755 | DMBT1 (deleted in malignant brain tumors 1) | 14541 | -1.266 | -0.5142 | No | ||
68 | 10170 | DHRS9 (dehydrogenase/reductase (SDR family) member 9) | 14778 | -1.410 | -0.5254 | No | ||
69 | 6703 | SPRR2D (small proline-rich protein 2D) | 14782 | -1.414 | -0.5250 | No | ||
70 | 9370 | "ADIPOQ (adiponectin, C1Q and collagen domain containing)" | 14810 | -1.425 | -0.5258 | No | ||
71 | 6943 | TCF21 (transcription factor 21) | 14828 | -1.436 | -0.5261 | No | ||
72 | 6608 | SMO (smoothened homolog (Drosophila)) | 14976 | -1.544 | -0.5328 | No | ||
73 | 7849 | PAX8 (paired box 8) | 15035 | -1.587 | -0.5351 | No | ||
74 | 5629 | PROX1 (prospero homeobox 1) | 15044 | -1.592 | -0.5349 | No | ||
75 | 6706 | SPRR2G (small proline-rich protein 2G) | 15209 | -1.730 | -0.5423 | No | ||
76 | 4435 | "CITED1 (Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1)" | 15894 | -2.354 | -0.5753 | No | ||
77 | 7379 | UPK2 (uroplakin 2) | 16100 | -2.639 | -0.5844 | No | ||
78 | 2627 | GATA6 (GATA binding protein 6) | 16122 | -2.667 | -0.5845 | No | ||
79 | 6899 | TBX1 (T-box 1) | 16186 | -2.739 | -0.5866 | No | ||
80 | 182 | JAG1 (jagged 1 (Alagille syndrome)) | 16647 | -3.487 | -0.6080 | No | ||
81 | 11045 | UPK1A (uroplakin 1A) | 17286 | -4.955 | -0.6377 | No | ||
82 | 163183 | C19orf46 (chromosome 19 open reading frame 46) | 17491 | -5.597 | -0.6457 | No | ||
83 | 84162 | KIAA1109 (KIAA1109) | 17555 | -5.847 | -0.6467 | No | ||
84 | 55897 | MESP1 (mesoderm posterior 1 homolog (mouse)) | 17684 | -6.362 | -0.6506 | No | ||
85 | 2535 | FZD2 (frizzled homolog 2 (Drosophila)) | 17958 | -7.681 | -0.6613 | No | ||
86 | 3664 | IRF6 (interferon regulatory factor 6) | 17986 | -7.831 | -0.6597 | No | ||
87 | 58495 | OVOL2 (ovo-like 2 (Drosophila)) | 18071 | -8.287 | -0.6607 | No | ||
88 | 652 | BMP4 (bone morphogenetic protein 4) | 18378 | -10.143 | -0.6721 | No | ||
89 | 8754 | ADAM9 (ADAM metallopeptidase domain 9 (meltrin gamma)) | 18549 | -11.504 | -0.6762 | No | ||
90 | 1999 | "ELF3 (E74-like factor 3 (ets domain transcription factor, epithelial-specific ))" | 19067 | -18.273 | -0.6950 | No | ||
91 | 25932 | CLIC4 (chloride intracellular channel 4) | 19379 | -25.066 | -0.7010 | Yes | ||
92 | 7026 | "NR2F2 (nuclear receptor subfamily 2, group F, member 2)" | 19595 | -31.444 | -0.6999 | Yes | ||
93 | 3911 | "LAMA5 (laminin, alpha 5)" | 19755 | -39.515 | -0.6930 | Yes | ||
94 | 26298 | EHF (ets homologous factor) | 19794 | -41.896 | -0.6793 | Yes | ||
95 | 360 | AQP3 (aquaporin 3 (Gill blood group)) | 19915 | -52.980 | -0.6655 | Yes | ||
96 | 1832 | DSP (desmoplakin) | 20110 | -82.287 | -0.6444 | Yes | ||
97 | 10628 | TXNIP (thioredoxin interacting protein) | 20127 | -86.954 | -0.6128 | Yes | ||
98 | 1475 | CSTA (cystatin A (stefin A)) | 20163 | -98.608 | -0.5778 | Yes | ||
99 | 3398 | "ID2 (inhibitor of DNA binding 2, dominant negative helix-loop-helix protein)" | 20185 | -106.279 | -0.5392 | Yes | ||
100 | 3169 | FOXA1 (forkhead box A1) | 20189 | -110.661 | -0.4981 | Yes | ||
101 | 4831 | "NME2 (non-metastatic cells 2, protein (NM23B) expressed in)" | 20205 | -117.742 | -0.4549 | Yes | ||
102 | 2947 | GSTM3 (glutathione S-transferase M3 (brain)) | 20280 | -185.916 | -0.3893 | Yes | ||
103 | 100133941 | CD24 (CD24 molecule) | 20284 | -192.287 | -0.3177 | Yes | ||
104 | 694 | "BTG1 (B-cell translocation gene 1, anti-proliferative)" | 20290 | -198.302 | -0.2440 | Yes | ||
105 | 2625 | GATA3 (GATA binding protein 3) | 20312 | -255.499 | -0.1498 | Yes | ||
106 | 10409 | "BASP1 (brain abundant, membrane attached signal protein 1)" | 20323 | -403.466 | 0.0001 | Yes |