Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
Phenotype | Phenotype.cls#treated_versus_cont_repos |
Upregulated in class | treated |
GeneSet | REACTOME|REACT_471.1 |
Enrichment Score (ES) | 0.8382848 |
Normalized Enrichment Score (NES) | 1.6048708 |
Nominal p-value | 0.004622496 |
FDR q-value | 0.052845787 |
FWER p-Value | 0.988 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | 6241 | RRM2 (ribonucleotide reductase M2 polypeptide) | 66 | 172.790 | 0.1678 | Yes | ||
2 | 5111 | PCNA (proliferating cell nuclear antigen) | 102 | 146.221 | 0.3109 | Yes | ||
3 | 891 | CCNB1 (cyclin B1) | 188 | 105.636 | 0.4113 | Yes | ||
4 | 7298 | TYMS (thymidylate synthetase) | 202 | 102.506 | 0.5121 | Yes | ||
5 | 983 | "CDC2 (cell division cycle 2, G1 to S and G2 to M)" | 618 | 53.980 | 0.5451 | Yes | ||
6 | 5557 | "PRIM1 (primase, DNA, polypeptide 1 (49kDa))" | 756 | 47.079 | 0.5850 | Yes | ||
7 | 7027 | TFDP1 (transcription factor Dp-1) | 1040 | 35.448 | 0.6061 | Yes | ||
8 | 990 | CDC6 (cell division cycle 6 homolog (S. cerevisiae)) | 1098 | 33.817 | 0.6368 | Yes | ||
9 | 23594 | "ORC6L (origin recognition complex, subunit 6 like (yeast))" | 1148 | 32.456 | 0.6665 | Yes | ||
10 | 1719 | DHFR (dihydrofolate reductase) | 1395 | 27.068 | 0.6812 | Yes | ||
11 | 23649 | "POLA2 (polymerase (DNA directed), alpha 2 (70kD subunit))" | 1598 | 23.976 | 0.6950 | Yes | ||
12 | 4998 | "ORC1L (origin recognition complex, subunit 1-like (yeast))" | 1658 | 23.133 | 0.7150 | Yes | ||
13 | 993 | CDC25A (cell division cycle 25 homolog A (S. pombe)) | 1742 | 21.819 | 0.7325 | Yes | ||
14 | 81620 | CDT1 (chromatin licensing and DNA replication factor 1) | 1790 | 21.205 | 0.7512 | Yes | ||
15 | 4999 | "ORC2L (origin recognition complex, subunit 2-like (yeast))" | 1830 | 20.770 | 0.7698 | Yes | ||
16 | 26271 | FBXO5 (F-box protein 5) | 1840 | 20.601 | 0.7898 | Yes | ||
17 | 5001 | "ORC5L (origin recognition complex, subunit 5-like (yeast))" | 2030 | 18.486 | 0.7988 | Yes | ||
18 | 5558 | "PRIM2 (primase, DNA, polypeptide 2 (58kDa))" | 2031 | 18.485 | 0.8171 | Yes | ||
19 | 8318 | CDC45L (CDC45 cell division cycle 45-like (S. cerevisiae)) | 2151 | 17.475 | 0.8285 | Yes | ||
20 | 898 | CCNE1 (cyclin E1) | 2376 | 15.333 | 0.8327 | Yes | ||
21 | 5422 | "POLA1 (polymerase (DNA directed), alpha 1, catalytic subunit)" | 2543 | 13.945 | 0.8383 | Yes | ||
22 | 1869 | E2F1 (E2F transcription factor 1) | 3409 | 9.131 | 0.8047 | No | ||
23 | 23595 | "ORC3L (origin recognition complex, subunit 3-like (yeast))" | 3538 | 8.626 | 0.8069 | No | ||
24 | 8900 | CCNA1 (cyclin A1) | 12493 | -0.453 | 0.3663 | No | ||
25 | 7084 | "TK2 (thymidine kinase 2, mitochondrial)" | 14428 | -1.197 | 0.2722 | No | ||
26 | 5925 | RB1 (retinoblastoma 1) | 17508 | -5.685 | 0.1261 | No | ||
27 | 5000 | "ORC4L (origin recognition complex, subunit 4-like (yeast))" | 18666 | -12.706 | 0.0817 | No |