Daniele Merico
Contact
Location: Emili Lab Area (6th Floor CCBR)BR Email: MailTo(daniele DOT merico AT gmail DOT com)BR Skype: the-amerigoBR Linked-In: [http://www.linkedin.com/profile?viewProfile=&key=4048991&goback=%2Econ-*3conbro*40*4*051*4false*4*02*40%2Ebcc_2220874_1/ Daniele Merico]BR
Research Projects
Current Projects @CCBR:
Active Cell Map (pathway & network: topology, expression profiling, activity patterns, etc...)
Supervised by: [:GaryBader:Gary Bader].
With: [:RuthIsserlin:Ruth Isserlin]. Supervised by: [http://lambda.med.utoronto.ca/Emili.htm/ Andrew Emili] and [:GaryBader:Gary Bader].
Almost-completed or on-going Projects @UNIMI/UNIMIB:
- Knowledge Engineering of Human Phenotypes
- With Gianluca Colombo. Supervised by: Giancarlo Mauri.
- Analysis of Time-course Microarray Data
- With Italo Zoppis. Supervised by: Marco Antoniotti.
- The p63 Network
- With Alessandra Viganò. Supervised by: Roberto Mantovani.
Ref & Links: [http://www.nature.com/emboj/journal/v25/n21/pdf/7601375a.pdf p63 EMBO Paper]
- With Alessandra Viganò. Supervised by: Roberto Mantovani.
Completed Projects @UNIMI/UNIMIB:
- Clinical Phenotype Ontology for Cerebrovascular Disorders (NEUROWEB Project)
- With Gianluca Colombo, Flavio De Paoli, Marco Antoniotti. Supervised by: Giancarlo Mauri.
Ref & Links: [http://www.nettab.org/2007/slides/SemanticWeb_Frisoni.pdf/ NETTAB 2007 presentation]; [http://nuke.neurowebkc.eu/Dissemination/tabid/66/Default.aspx/ published papers & proceedings].
- With Gianluca Colombo, Flavio De Paoli, Marco Antoniotti. Supervised by: Giancarlo Mauri.
- The Landscape of NF-Y Binding
- With: Michele Ceribelli, Diletta Dolfini. Supervised by: Roberto Mantovani.
Ref & Links: (2 accepted papers)
- With: Michele Ceribelli, Diletta Dolfini. Supervised by: Roberto Mantovani.
Work Logs
(To be filled yet...)
Knowledge Sharing
Here's the knowledge & expertise I wish to share with anybody who wants to.
Computational techniques & resources:
PCA (Principal Correspondence Analysis) & CA (Correspondence Analysis)
- Correlation Measures (Pearson, Spearman)
- Standard Affymetrix Microarray Analysis
- (CEL files handling, Normalization, Signal computation (e.g. rma), Exploratory Analysis, Differentially Expressed Genes)
- Clustering (hirerarchical, K-means, CLICK, etc...)
- Statistical tests (t-test, Fisher's)
- Gene Ontology
I usually program with:
[http://cran.r-project.org/ R] (see also [http://www.bioconductor.org/ Bioconductor])
Go to my [:DmHowtoDirectory: How To Directory] for tips with R programming.
Biological Systems and Pathologies I've been working on (in order of confidence):
- Mammalian Immune System (focus on Dendritic Cells)
Ischemic Stroke & Atherosclerosis
- Mammalian Chromatin Modification
- Yeast Cell Cycle
Resume & CV
I was born in Saronno (VA, Italy) in 29/07/1981. I lived, studied and worked in the Milan metropolitan area till November 2007. I got my BSc in Molecular Biotechnologies (July 2003) and my MSc Bioinformatics (July 2005) at Università di Milano-Bicocca. I started my PhD in Molecular and Cellular Biology at Università di Milano in 2005.BR My scientific interests are:
- Pathways and Networks
- Human Phenotypes
- Expression Data and Transcriptional Regulation
Biomedical Knowledge Engineering & Representation
- Philosophy and Sociology of Science
For more details, please have a look at my CV: [attachment:DanieleMericoCV.PDF CV.PDF].
Affiliations
CCBR - Banting & Best Dept. of Medical Research
- Visiting PhD student
Università di Milano ([http://www.unimi.it UNIMI]) - Dipartimento di Scienze Biomolecolari e Biotecnologie ([http://bimib.disco.unimib.it/ DSBB])
PhD student (Program of Cellular and Molecular Biology)BR [http://www.bsb.unimi.it/gene_expression.htm Roberto Mantovani's Lab]
Università di Milano-Bicocca ([http://www.unimib.it UNIMIB]) - Dipartimento di Informatica ([http://www.disco.unimib.it/ DISCo])
External PhD studentBR [http://www.sbb.unimi.it/ BiMIB Group] (Bioinformatics at Milano-Bicocca)
Trivia & Amenities
I like to...
- travel, and discover new cultures
- meet people
- discuss ideas
- take more than 45' to have lunch or dinner
- swim, walk, trek
- write runes (still have to learn ideograms...)
- drink beer
- throw snowballs (look out...)
laugh
