Daniele Merico
Contact
Physical location: Emili Lab Area (6th Floor CCBR)BR Email: MailTo(daniele DOT merico AT gmail DOT com)BR Skype: the-amerigo Linked-In: [http://www.linkedin.com/profile?viewProfile=&key=4048991&goback=%2Econ-*3conbro*40*4*051*4false*4*02*40%2Ebcc_2220874_1/ Daniele Merico]BR
Research Projects
Current Projects @CCBR:
Active Cell Maps (pathway & network: topology, expression profiling, activity patterns, etc...)
Supervised by: [:GaryBader:Gary Bader].
With: [:RuthIsserlin:Ruth Isserlin]. Supervised by: [http://lambda.med.utoronto.ca/Emili.htm/ Andrew Emili] and [:GaryBader:Gary Bader].
Almost-completed or on-going Projects @UNIMIB:
- Knowledge Engineering of Human Phenotypes
- With Gianluca Colombo. Supervised by: Giancarlo Mauri.
- Analysis of Time-course Microarray Data
- With Italo Zoppis. Supervised by: Marco Antoniotti.
Completed Projects @UNIMI / UNIMIB:
- Clinical Phenotype Ontology for Cerebrovascular Disorders (NEUROWEB Project)
- With Gianluca Colombo, Flavio De Paoli, Marco Antoniotti. Supervised by: Giancarlo Mauri.
Links: [http://www.nettab.org/2007/slides/SemanticWeb_Frisoni.pdf/ NETTAB 2007 presentation]; [http://nuke.neurowebkc.eu/Dissemination/tabid/66/Default.aspx/ published papers].
- With Gianluca Colombo, Flavio De Paoli, Marco Antoniotti. Supervised by: Giancarlo Mauri.
- The Landscape of NF-Y Binding
- With: Michele Ceribelli, Diletta Dolfini. Supervised by: Roberto Mantovani.
Knowledge Sharing
Here's the knowledge & expertise I wish to share with anybody who wants to.
Expertise on computational techniques & resources:
PCA (Principal Correspondence Analysis) & CA (Correspondence Analysis)
- Correlation Measures (Pearson, Spearman)
- Standard Affymetrix Microarray Analysis
- (CEL files handling, Normalization, Signal computation (e.g. rma), Exploratory Analysis, Differentially Expressed Genes)
- Clustering (hirerarchical, K-means, CLICK, etc...)
- Statistical tests (t-test, Fisher's)
- Gene Ontology
I usually program with:
[http://cran.r-project.org/ R] (see also [http://www.bioconductor.org/ Bioconductor])
Biological Systems and Pathologies I've been working on (in order of confidence):
- Mammalian Immune System (focus on Dendritic Cells)
Ischemic Stroke & Atherosclerosis
- Mammalian Chromatin Modification
- Yeast Cell Cycle