A pathway analysis/precision medicine version:
Gary Bader is a Professor at The Donnelly Centre at the University of Toronto and an international leader in the field of Computational Biology. The Bader lab uses molecular interaction, pathway and ‘omics data to gain a ‘causal’ mechanistic understanding of normal and disease phenotypes. They are developing novel computational approaches that combine molecular interaction and pathway information with ‘omics data to develop clinically predictive models and identify therapeutically targetable pathways. This research, for instance, helped identify a histone methylation inhibitor as the first therapeutic candidate for pediatric ependymoma, a common childhood brain cancer (work with Michael Taylor at SickKids). See http://baderlab.org
And a single cell genomics version:
Gary Bader is a Professor at The Donnelly Centre at the University of Toronto and an expert in Computational Biology. The Bader lab is developing computational methods and an ecosystem theory of tissue function that considers cell-cell interactions, cell growth, and cell internal mechanisms, such as pathways, reactions, and causal relationships, to help understand development, cancer and regenerative wound healing processes. See http://baderlab.org
Gary Bader completed post-doctoral work in the group of Chris Sander in the Computational Biology Center (cBio) at Memorial Sloan-Kettering Cancer Center in New York. Gary developed the Biomolecular Interaction Network Database (BIND) during his PhD in the lab of Christopher Hogue in the Department of Biochemistry at the University of Toronto and the Samuel Lunenfeld Research Institute at Mount Sinai Hospital in Toronto. He completed a BSc in Biochemistry at McGill University in Montreal.
The Donnelly Centre is an interdisciplinary centre at the University of Toronto (UofT), with many UofT departments represented and with occupants usually cross-appointed to many departments.
The Donnelly Centre
The Lunenfeld-Tanenbaum Research Institute at Sinai Health System
Princess Margaret Cancer Centre at University Health Network
Department of Molecular Genetics
Department of Computer Science
Collaborative Graduate Program in Genome Biology and Bioinformatics
all associated with the University of Toronto
gary.bader *a-t* utoronto.ca
Physical work location
The Donnelly Centre
University of Toronto
160 College Street, Room 602
Canada, M5S 3E1
- There are two other Bader labs in computational biology led by Joel and David Bader, respectively. They are brothers, but I am not related to them.
- Check out:
Wiki pages of interest