Bader Lab
Computational Network Biology
We study the organization and evolution of biological systems using computational biology and bioinformatics techniques. We seek to accurately predict links, such as specific molecular interactions, in eukaryotic cell signaling systems using comprehensive genomics data like genome sequence and transcript profiles. We are interested to find how these links are rewired by mutations to cause disease. This work is supported through the development of open-source biological pathway and network databases and visualization and analysis software.
- Predicting biologically relevant protein interactions
- Cellular network evolution
- Detection of cell type and stage active biological processes using molecular profiles
- Biological pathway and network databases and analysis tools
[:ResearchNonExpert:Non-expert explanation]BR [attachment:InnerCellLife.mov Watch the Inner Life of the Cell movie from Harvard]
Affiliations:BR Include(Affiliations)
Where we are:BR160 College Street, Room 602BRTerrence Donnelly Centre for Cellular and Biomolecular ResearchBRUniversity of TorontoBRToronto, OntarioBRCanada, M5S 3E1BRBR[http://maps.google.com/maps?f=q&hl=en&q=160+College+St,+Toronto+ON&om=1 Map] [http://www.news.utoronto.ca/photogalleries/ccbr/slideshow1.htm Pictures] ["TDCCBR 6th Floor"] |
Contact:BRGary BaderBRPhone: 416-978-3935BRFax: 416-978-8287BRgary.bader *a-t* utoronto.caBRAlso available by Skype (preferred), iChat, AIM |
[http://www.plos.org Support Open Access Publishing]