6321529,6321757,6320828,6319749,6320801,6322777,6324244,6321671,6320849,6325360,14318575,6323974,6324535,6319430,6323547,6321574,6320941,6320798,6321021,6324079,6324039,6324478,6321816,6321994,14318526,14318577,6323453,6320859,6320184,6320054,6320106,6325365,6324835,6320635,6322704,6320197,6320602,6324833,6324691,6321390,6321427,14318532,6319432,6321434,6323940,6325187
GI	Gene Name	Description	Essential	Cell localization	Biochemical function	Cell role	Synonyms
6321529	Dbf2	kinase required for late nuclear division	N	nuclear	protein kinase	Signal transduction	Dbf2, YGR092W, G4643
6321757	Ecm29	ExtraCellular Mutant	N	extracellular, including cell wall	Unknown	Cell wall maintenance	Ecm29, YHL030W
6320828	Gcn4	transcriptional activator of amino acid biosynthetic genes	N	nuclear	transcription factor	Amino-acid metabolism,Cell stress,Nucleotide metabolism,Pol II transcription	Gcn4, YEL009C, ARG9, AAS3
6319749	Hsm3	Involved in DNA mismatch repair pathways	N	Unknown	Unknown	DNA repair	Hsm3, YBR272C, YBR1740
6320801	Hyp2	Translation initiation factor eIF-5A	Y	cytoplasmic	Translation factor	Protein synthesis	Hyp2, YEL034W, TIF51A, TDS3, tr-2, SYGP-ORF21
6322777	Lhs1	Required for efficient translocation of protein precursors across the ER membrane, Lumen HSP Seventy<br> Required for efficient translocation of protein precursors across the ER membrane	N	endoplasmic reticulum	Chaperones	Protein translocation	Lhs1, YKL073W, SSI1, CER1, PER4, YKL355
6324244	Mkt1	Protein involved in propagation of M2 dsRNA satellite of L-A virus	N	Unknown	Unknown	Unknown	Mkt1, YNL085W, N2302
6321671	Nas6	Interaction with the 19S regulatory particle of the 26S proteasome detected by coimmunoprecipitation.	N	Unknown	Unknown	Unknown	Nas6, YGR232W, ORF228, G8564
6320849	Pre1	Required for mitotic division and sporulation	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre1, YER012W, CST28
6325360	Pre2	proteasome subunit	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre2, YPR103W, SRR2, PRG1, DOA3, P8283.15
14318575	Pre4	B-type subunit of proteasome, euk. & archae. multicatalytic proteinase complex likelyinvolved in an ATP/ubiquitin-dependent nonlysosomal proteolytic pathway. eukary: the proteasome is composed of ~24 subunits forming a ring-shaped structure	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre4, YFR050C
6323974	Pre5	alpha-type of subunit of 20S proteasome	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre5, YMR314W, YM9924.06
6324535	Pre6	alpha-type of subunit of 20S proteasome	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre6, YOL038W, O2065
6319430	Pre7	proteasome subunit	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre7, YBL041W, PTS1, YBL0407
6323547	Pre8	proteasome component Y7	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre8, YML092C, TAN1, Y7
6321574	Pre9	proteasome component Y13	N	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pre9, YGR135W, Y13, G6405
6320941	Pup3	20S proteasome subunit beta3_sc	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Pup3, YER094C, SCS32, CST27
6320798	Rad23	ubiquitin-like protein	N	nuclear	Unknown	DNA repair	Rad23, YEL037C, SYGP-ORF29
6321021	Rad24	checkpoint protein	N	nuclear	Unknown	Cell cycle control,DNA repair	Rad24, YER173W, RS1, SYGP-ORF60
6324079	Rad50	coiled-coil protein, contains a purine-binding domain, two heptad repeats and a hydrophobic tail	N	nuclear	Hydrolase	Chromatin/chromosome structure,Recombination,DNA repair,Meiosis	Rad50, YNL250W, N0872
6324039	Rfc3	RFC is a DNA binding protein and ATPase that acts as a processivity factor for DNA polymerases delta and epsilon and loads proliferating cell nuclear antigen (PCNA) on DNA	Y	nuclear	ATPase	DNA synthesis	Rfc3, YNL290W, N0533, YNL0533
6324478	Rfc4	RFC is a DNA binding protein and ATPase that acts as a processivity factor for DNA polymerases delta and epsilon and loads proliferating cell nuclear antigen (PCNA) on DNA	Y	nuclear	DNA-binding protein	DNA synthesis	Rfc4, YOL094C, O0923
6321816	Rpn1	Subunit of 26S Proteasome (PA700 subunit)	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn1, YHR027C, NAS1, HRD2
6321994	Rpn10	homolog of the mammalian S5a protein, component of 26S proteasome	N	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn10, YHR200W, SUN1, MCB1
14318526	Rpn11	Suppressor of mutant (ts on glycerol) tRNA gene deficient in the processing of its 3'-end; homologous to S. pombe PAD1 gene - global positive regulator of nuclear transcription and is involved in maintenance of chromatin structure	Y	nuclear, cytoplasmic, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn11, YFR004W, MPR1
14318577	Rpn12	Part of 26S proteasome complex that may activate Cdc28p	Y	nuclear, cytoplasmic, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn12, YFR052W, NIN1
6323453	Rpn13	Proteasome subunit	N	Unknown	proteasomal protein	Protein degradation	Rpn13, YLR421C, DAQ1
6320859	Rpn3	proteasome subunit	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn3, YER021W, SUN2
6320184	Rpn4	involved in ubiquitin degradation pathway	N	nuclear, endoplasmic reticulum	proteasomal protein	Pol II transcription,Protein degradation	Rpn4, YDL020C, UFD5, SON1, PER8, GVM1, D2840
6320054	Rpn5	Regulatory Particle Non-ATPase, homolog of mammalian proteasomal subunit p55	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn5, YDL147W, NAS5, D1572
6320106	Rpn6	Regulatory Particle Non-ATPase, homolog of mammalian proteasomal subunit S9/p44.5.	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn6, YDL097C, NAS4, D2381
6325365	Rpn7	Regulatory Particle Non-ATPase, homolog of mammalian proteasomal subunit S10/p44	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn7, YPR108W, P8283.8
6324835	Rpn8	Regulatory Particle Non-ATPase, homolog of mammalian proteasomal subunit S12/p40	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn8, YOR261C, NAS3, O5360
6320635	Rpn9	Regulatory Particle Non-ATPase	N	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Rpn9, YDR427W, D9461.14
6322704	Rpt1	Required for degradation of ubiquitinated substrates and for anaphase chromosome separation	Y	nuclear, endoplasmic reticulum	conserved ATPase domain (CDC48/PAS1/SEC18 family)	Protein degradation	Rpt1, YKL145W, YTA3, CIM5
6320197	Rpt2	Probable 26S protease subunit and member of CDC48/PAS1/SEC18 family of ATPases	Y	nuclear, endoplasmic reticulum	conserved ATPase domain (CDC48/PAS1/SEC18 family)	Protein degradation	Rpt2, YDL007W, YTA5, YHS4, D2920
6320602	Rpt3	probable 26S protease subunit and member of the CDC48/PAS1/SEC18 family of ATPases	Y	nuclear, endoplasmic reticulum	conserved ATPase domain (CDC48/PAS1/SEC18 family)	Protein degradation	Rpt3, YDR394W, YTA2, YNT1, D9509.14
6324833	Rpt4	Proteasome Cap Subunit	Y	nuclear, endoplasmic reticulum	conserved ATPase domain (CDC48/PAS1/SEC18 family)	Protein degradation	Rpt4, YOR259C, SUG2, PCS1, CRL13, O5345
6324691	Rpt5	Probable 26S protease subunit and member of the CDC48/PAS1/SEC18 family of ATPases	Y	nuclear, endoplasmic reticulum	conserved ATPase domain (CDC48/PAS1/SEC18 family)	Protein degradation	Rpt5, YOR117W, YTA1, O3258, YOR3258
6321390	Rpt6	member of the 26 S proteasome	Y	nuclear, endoplasmic reticulum	conserved ATPase domain (CDC48/PAS1/SEC18 family)	Protein degradation	Rpt6, YGL048C, SUG1, SCB68, CRL3, CIM3, TBY1, TBPY, G3514
6321427	Scl1	Proteasome subunit YC7alpha/Y8 (protease yscE subunit 7)	Y	nuclear, endoplasmic reticulum	proteasomal protein	Protein degradation	Scl1, YGL011C, PRC2, YC7ALPHA, YC7, Y8, PRCI, G3728
14318532	Ubp6	deubiquitinating enzyme (putative)	N	Unknown	Protease (other than proteasomal)	Protein degradation,Protein modification	Ubp6, YFR010W
6319432	Ura7	Last step in pyrimidine biosynthesis pathway; URA7 is very similar to URA8 CTP synthase	N	Unknown	Ligase	Nucleotide metabolism	Ura7, YBL039C, YBL0410
6321434	Ygl004c	Hypothetical ORF	N	Unknown	Unknown	Unknown	Ygl004c, G3762
6323940	Yku70	Shows homology to 70-kDa subunit of mammalian Ku protein, the regulatory subunit of the DNA-dependent protein kinase	N	nuclear	DNA-binding protein	Chromatin/chromosome structure,Recombination,DNA repair	Yku70, YMR284W, NES24, HDF1, KU70, YM8021.10
6325187	Ypl070w	Hypothetical ORF	N	Unknown	Unknown	Unknown	Ypl070w, LPF14
