6323335,6319612,6322192,6320302,6323752,6319436,6320775,6322992,6323609,6320281,6320207,6319321,6324017,6322288,6323890,6320396,6323940
GI	Gene Name	Description	Essential	Cell localization	Biochemical function	Cell role	Synonyms
6323335	Aco1	Aconitase, mitochondrial	N	mitochondrial	Lyase	Amino-acid metabolism,Carbohydrate metabolism,Energy generation	Aco1, YLR304C, GLU1, L8003.22
6319612	Mec1	Required for mitotic growth, DNA repair and mitotic recombination, regulates phosporylation of Rad53p, required for dmc1 arrest and meiotic recombination	Y	Unknown	Transferase	Cell cycle control,Chromatin/chromosome structure,Recombination,Protein degradation,DNA repair,DNA synthesis	Mec1, YBR136W, SAD3, ESR1, YBR1012
6322192	Mph1	Mutator PHenotype; Similar to ATP-dependent RNA helicases	N	nuclear	Hydrolase	RNA processing/modification	Mph1, YIR002C, YIB2
6320302	Msh6	Required for mismatch repair in mitosis & meiosis, low levels of postmeiotic segregation & high spore viability; forms complex with Msh2p to repair both single-base & insertion-deletion mispairs; redundant with Msh3p in repair of in-dels	N	nuclear	ATPase	DNA repair	Msh6, YDR097C, PMS3, YD8557.04
6323752	Pgm2	Phosphoglucomutase	N	cytoplasmic	Isomerase	Carbohydrate metabolism,Protein modification	Pgm2, YMR105C, GAL5, YM9718.04
6319436	Pol12	Required for DNA synthesis and correct progression through S phase; plays an essential role at early stage of chromosomal DNA replication, before the hydroxyurea-sensitive step	Y	nuclear	DNA polymerase or subuni	DNA synthesis	Pol12, YBL035C, YBL0414
6320775	Prb1	dispensable for haploidization and sporulation, but needed for full protein degradation during sporulation, and proper spore morphology	N	Lysosome/vacuole	Protease (other than proteasomal)	Protein degradation	Prb1, YEL060C, CVT1
6322992	Prp19	Required for error prone repair, induced mitotic recombination, and sporulation	Y	nuclear	DNA-binding protein	RNA processing/modification,RNA splicing,DNA repair	Prp19, YLL036C, PSO4, L0913
6323609	Rad52	Required for X-ray damage repair & various types of intra- and interchr. mitotic recombination, including HO switching & plasmid exchange. Disp. for premeiotic DNA synthesis, double strand breaks & heteroduplex formation.	N	nuclear	DNA-binding protein	Chromatin/chromosome structure,Recombination,DNA repair,Meiosis,Mitosis	Rad52, YML032C
6320281	Rad55	Required for X-ray damage repair, full sporulation and viable spores	N	nuclear	DNA-binding protein	Recombination,DNA repair	Rad55, YDR076W, XS9, D4426, YD8554.09
6320207	Rad57	Required for X-ray damage repair, meiotic recombination, wild-type levels of sporulation and viable spores	N	nuclear	Unknown	Recombination,DNA repair	Rad57, YDR004W, YD8119.10, D2970
6319321	Rfa1	Required for DNA-damage repair, full levels of gene conversion and sporulation	Y	nuclear	DNA-binding protein	Recombination,DNA repair,DNA synthesis	Rfa1, YAR007C, RPA1, FUN3, BUF2, SRR1
6324017	Rfa2	Involved in nucleotide excision repair	Y	nuclear	DNA-binding protein	Recombination,DNA repair,DNA synthesis	Rfa2, YNL312W, BUF1, N0368
6322288	Rfa3	subunit 3 of replication factor-A	Y	nuclear	DNA-binding protein	Recombination,DNA repair,DNA synthesis	Rfa3, YJL173C, J0506
6323890	Rnh1	ribonuclease H	N	Unknown	Hydrolase	Cell wall maintenance,RNA processing/modification,DNA repair,DNA synthesis	Rnh1, YMR234W, YM9959.16
6320396	Rvb1	RUVB-like protein, TIP49a Homologue	Y	nuclear	Hydrolase	RNA processing/modification,Pol II transcription,DNA repair	Rvb1, YDR190C, TIP49A, TIH1, YD9346.02
6323940	Yku70	Shows homology to 70-kDa subunit of mammalian Ku protein, the regulatory subunit of the DNA-dependent protein kinase	N	nuclear	DNA-binding protein	Chromatin/chromosome structure,Recombination,DNA repair	Yku70, YMR284W, NES24, HDF1, KU70, YM8021.10
