Positive Selection of Tyrosine Loss in Metazoan Evolution
This page contain associated data used in:
Positive Selection of Tyrosine Loss in Metazoan Evolution
Chris S.H Tan1,2, Adrian Pasculescu1, Wendell A. Lim4, Tony Pawson1,2*, Gary D. Bader1,2,3*, Rune Linding5*
1. Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. 2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada 3. Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada 4. Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA. 5. Cellular and Molecular Logic Team, Section of Cell and Molecular Biology, The Institute of Cancer Research (ICR), London, UK
* To whom correspondence should be addressed. E-mail: pawson@lunenfeld.ca (TP); gary.bader@utoronto.ca (GDB); linding@icr.ac.uk (RL)
Supplemental Materials
Supplementary Materials.doc - Supplementary Notes 1-4 and Figure S1-6 with legends
Supplemental Tables
Table S1 - Quantitative Mouse PDZ Domain-peptide Interaction Matrix
Table S2 - Performance on Different Encoding
Table S7 - Predicted Affinity Score for Putative Mouse PDZ Domain-peptide Pairs
Table S8 - Predicted Affinity Score for Putative Human PDZ Domain-peptide Pairs
Semi-quantitative Support Vector Regression Code
SemiSVR_code.Zip - Matlab code for SemiSVR (compressed).
PDZ Sequence
Mouse PDZ sequence : MousePDZSequence.fasta
SemiSVR Predictable Human PDZ Sequence : SemiSVR_Predictable_HumanPDZSequence.fasta
SemiSVR Predictable Mouse PDZ Sequence : SemiSVR_Predictable_MousePDZSequence.fasta