|
Size: 2161
Comment:
|
Size: 1317
Comment:
|
| Deletions are marked like this. | Additions are marked like this. |
| Line 3: | Line 3: |
| This page contain associated data used in: | <<BR>><<BR>> This page contain associated data used in: <<BR>><<BR>> ''Positive Selection of Tyrosine Loss in Metazoan Evolution'' <<BR>><<BR>> Chris S.H Tan^1,2^, Adrian Pasculescu^1^, Wendell A. Lim^4^, Tony Pawson^1,2*^, Gary D. Bader^1,2,3*^, Rune Linding^5*^ <<BR>><<BR>> |
| Line 5: | Line 10: |
| ''Positive Selection of Tyrosine Loss in Metazoan Evolution'' | 1. Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. 2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada 3. Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada 4. Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA. 5. Cellular and Molecular Logic Team, Section of Cell and Molecular Biology, The Institute of Cancer Research (ICR), London, UK |
| Line 7: | Line 16: |
| Chris S.H Tan^1,2^, Adrian Pasculescu^1^, Wendell A. Lim^4^, Tony Pawson^1,2*^, Gary D. Bader^1,2,3*^, Rune Linding^5*6 | * To whom correspondence should be addressed. E-mail: pawson@lunenfeld.ca (TP); gary.bader@utoronto.ca (GDB); linding@icr.ac.uk (RL) == Supplemental Materials == * [[attachment:SupplementaryMaterials.pdf]] - Supplementary Notes 1-4 and Figure S1-6 with legends == Supplemental Tables == == Semi-quantitative Support Vector Regression Code == |
| Line 10: | Line 27: |
| 1. Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. 2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada 3. Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada 4. Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA. 5. Cellular and Molecular Logic Team, Section of Cell and Molecular Biology, The Institute of Cancer Research (ICR), London, UK * To whom correspondence should be addressed. E-mail: gary.bader@utoronto.ca (GDB); dengnaiyang@cau.edu.cn (NYD) == Supplemental Materials == * [[attachment:Supplementary Materials.doc]] - Supplementary Notes 1-4 and Figure S1-6 with legends == Supplemental Tables == * [[attachment:MousePDZdomainpeptideMap.xls|Table S1]] - Quantitative Mouse PDZ Domain-peptide Interaction Matrix * [[attachment:SemiSVR_DifferentEncoding.xls|Table S2]] - Performance on Different Encoding * [[attachment:SemiSVR_Prediction_MousePDZ.xls|Table S7]] - Predicted Affinity Score for Putative Mouse PDZ Domain-peptide Pairs * [[attachment:SemiSVR_Prediction_HumanPDZ.xls|Table S8]] - Predicted Affinity Score for Putative Human PDZ Domain-peptide Pairs == Semi-quantitative Support Vector Regression Code == * [[attachment:SemiSVR_code.Zip]] - Matlab code for SemiSVR (compressed). |
|
| Line 35: | Line 28: |
| * Mouse PDZ sequence : [[attachment:MousePDZSeq.fasta|MousePDZSequence.fasta]] * SemiSVR Predictable Human PDZ Sequence : [[attachment:SemiSVRpredictable_HumanPDZdomain.fa|SemiSVR_Predictable_HumanPDZSequence.fasta]] * SemiSVR Predictable Mouse PDZ Sequence : [[attachment:SemiSVRpredictable_MousePDZdomain.fa|SemiSVR_Predictable_MousePDZSequence.fasta]] |
Positive Selection of Tyrosine Loss in Metazoan Evolution
This page contain associated data used in:
Positive Selection of Tyrosine Loss in Metazoan Evolution
Chris S.H Tan1,2, Adrian Pasculescu1, Wendell A. Lim4, Tony Pawson1,2*, Gary D. Bader1,2,3*, Rune Linding5*
1. Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. 2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada 3. Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada 4. Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA. 5. Cellular and Molecular Logic Team, Section of Cell and Molecular Biology, The Institute of Cancer Research (ICR), London, UK
* To whom correspondence should be addressed. E-mail: pawson@lunenfeld.ca (TP); gary.bader@utoronto.ca (GDB); linding@icr.ac.uk (RL)
Supplemental Materials
SupplementaryMaterials.pdf - Supplementary Notes 1-4 and Figure S1-6 with legends
Supplemental Tables
Semi-quantitative Support Vector Regression Code