Affiliate Scientist at the Princess Margaret Cancer Centre, University Health Network
Research Associate at the Donnelly Center for Cellular and Biomolecular Research, University of Toronto
Mohamed Ghadie completed his PhD and Postdoctoral work in Biomedical Engineering with Prof. Yu (Brandon) Xia at McGill University in Montreal, where he developed a multi-scale approach for in silico modelling of the cell by applying template-based methods to construct atomic-resolution structural models of nodes and edges in the human protein-protein interaction network ("interactome"). This multi-scale model of the cell enabled him to predict how the human interactome is perturbed by genetic mutations, and remodelled in different tissues and cell types through alternative splicing. Before that he completed his Masters degree in Electrical and Computer Engineering specializing in bioinformatics with Prof. Theodore Perkins at the Ottawa Hospital Research Institute, where he developed computational methods for analyzing high-throughput gene expression data in human blood stem cell differentiation. He completed his BASc in Electrical Engineering and Computing Technology at the University of Ottawa.
Email: mohamed.ghadie *a-t* uhnresearch.ca