Daniele Merico

Contact

Physical location: Emili Lab Area (6th Floor CCBR)BR Email: MailTo(daniele DOT merico AT gmail DOT com)BR Skype: the-amerigoBR Linked-In: [http://www.linkedin.com/profile?viewProfile=&key=4048991&goback=%2Econ-*3conbro*40*4*051*4false*4*02*40%2Ebcc_2220874_1/ Daniele Merico]BR

Research Projects

Current Projects @CCBR:

• Active Cell Maps (pathway & network: topology, expression profiling, activity patterns, etc...)

  • Supervised by: [:GaryBader:Gary Bader].

• MouseHeartPathwayProject

  • With: [:RuthIsserlin:Ruth Isserlin]. Supervised by: [http://lambda.med.utoronto.ca/Emili.htm/ Andrew Emili] and [:GaryBader:Gary Bader].

Almost-completed or on-going Projects @UNIMIB:

• Knowledge Engineering of Human Phenotypes
  • With Gianluca Colombo. Supervised by: Giancarlo Mauri.
• Analysis of Time-course Microarray Data
  • With Italo Zoppis. Supervised by: Marco Antoniotti.

Completed Projects @UNIMI / UNIMIB:

• Clinical Phenotype Ontology for Cerebrovascular Disorders (NEUROWEB Project)
  • With Gianluca Colombo, Flavio De Paoli, Marco Antoniotti. Supervised by: Giancarlo Mauri.

    Links: [http://www.nettab.org/2007/slides/SemanticWeb_Frisoni.pdf/ NETTAB 2007 presentation]; [http://nuke.neurowebkc.eu/Dissemination/tabid/66/Default.aspx/ published papers].

• The Landscape of NF-Y Binding
  • With: Michele Ceribelli, Diletta Dolfini. Supervised by: Roberto Mantovani.

Knowledge Sharing

Here's the knowledge & expertise I wish to share with anybody who wants to.

Expertise on computational techniques & resources:

• PCA (Principal Correspondence Analysis) & CA (Correspondence Analysis)

• Correlation Measures (Pearson, Spearman)
• Standard Affymetrix Microarray Analysis
  • (CEL files handling, Normalization, Signal computation (e.g. rma), Exploratory Analysis, Differentially Expressed Genes)
• Clustering (hirerarchical, K-means, CLICK, etc...)
• Statistical tests (t-test, Fisher's)
• Gene Ontology

I usually program with:

• [http://cran.r-project.org/ R] (see also [http://www.bioconductor.org/ Bioconductor])

Biological Systems and Pathologies I've been working on (in order of confidence):

• Mammalian Immune System (focus on Dendritic Cells)

• Ischemic Stroke & Atherosclerosis

• Mammalian Chromatin Modification
• Yeast Cell Cycle

Resume & CV

I was born in Saronno (VA, Italy) in 29/07/1981. I lived, studied and worked in the Milan metropolitan area till November 2007. I got my BSc in Molecular Biotechnologies (July 2003) and my MSc Bioinformatics (July 2005) at Università di Milano-Bicocca. I started my PhD in Molecular and Cellular Biology at Università di Milano in 2005.BR My scientific interests are:

• Pathways and Networks
• Human Phenotypes
• Expression Data and Transcriptional Regulation

• Biomedical Knowledge Engineering & Representation

• Philosophy and Sociology of Science

For more details, please have a look at my CV: [].

Trivia & Amenities

I like to...

• travel, and discover new cultures
• meet people
• discuss ideas
• take more than 45' to have lunch or dinner
• swim, walk, trek
• write runes (still have to learn ideograms...)
• drink beer

• laugh

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