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| Physical location: Emili Lab Area (6th Floor CCBR)[[BR]] Email: [[MailTo(daniele DOT merico AT gmail DOT com)]][[BR]] Skype: the-amerigo[[BR]] Linked-In: [http://www.linkedin.com/profile?viewProfile=&key=4048991&goback=%2Econ-*3conbro*40*4*051*4false*4*02*40%2Ebcc_2220874_1/ Daniele Merico][[BR]] | __Location__: Common Lab Area, 6th Floor (CCBR)[[BR]] __Email__: [[MailTo(daniele DOT merico AT gmail DOT com)]][[BR]] __Skype__: the-amerigo[[BR]] __Linked-In__: [http://www.linkedin.com/profile?viewProfile=&key=4048991&goback=%2Econ-*3conbro*40*4*051*4false*4*02*40%2Ebcc_2220874_1/ Daniele Merico][[BR]] | 
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| Current Projects @CCBR: * Active Cell Maps (pathway & network: topology, expression profiling, activity patterns, etc...) | __Current Projects @CCBR__: * '''Active Cell Map''' (pathway & network: topology, expression profiling, activity patterns, etc...) | 
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| * MouseHeartPathwayProject | * '''MouseHeartPathwayProject''' | 
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| Almost-completed or on-going Projects @UNIMIB: | __Almost-completed or on-going Projects @UNIMI/UNIMIB__: | 
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| * The p63 Network With Alessandra Viganò. Supervised by: Roberto Mantovani. Ref & Links: [http://www.nature.com/emboj/journal/v25/n21/pdf/7601375a.pdf p63 EMBO Paper] | |
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| Completed Projects @UNIMI / UNIMIB: | __Completed Projects @UNIMI/UNIMIB__: | 
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| Links: [http://www.nettab.org/2007/slides/SemanticWeb_Frisoni.pdf/ NETTAB 2007 presentation]; [http://nuke.neurowebkc.eu/Dissemination/tabid/66/Default.aspx/ published papers]. | Ref & Links: [http://www.nettab.org/2007/slides/SemanticWeb_Frisoni.pdf NETTAB 2007 presentation]; [http://nuke.neurowebkc.eu/Dissemination/tabid/66/Default.aspx/ published papers & proceedings]. | 
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| Ref & Links: (2 accepted papers) === Work Logs === [:DanieleMerico/WorkLogDirectory: Work logs] will be visible only to restricted lab personnel. | |
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| Expertise on computational techniques & resources: | __Computational techniques & resources__: | 
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| Biological Systems and Pathologies I've been working on (in order of confidence): | Go to my [:DanieleMerico/HowtoDirectory: How To Directory] for tips with R programming. __Biological Systems and Pathologies__ I've been working on (in order of confidence): | 
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| For more details, please have a look at my CV: []. | For more details, please have a look at my CV: [attachment:DanieleMericoCV.PDF CV.PDF]. === Affiliations === * CCBR - Banting & Best Dept. of Medical Research Visiting PhD student * Università di Milano ([http://www.unimi.it UNIMI]) - Dipartimento di Scienze Biomolecolari e Biotecnologie ([http://www.sbb.unimi.it/ DSBB]) PhD student (Program of Cellular and Molecular Biology)[[BR]] [http://www.bsb.unimi.it/gene_expression.htm Roberto Mantovani's Lab] * Università di Milano-Bicocca ([http://www.unimib.it UNIMIB]) - Dipartimento di Informatica ([http://www.disco.unimib.it/ DISCo]) External PhD student[[BR]] [http://bimib.disco.unimib.it/ BiMIB Group] (Bioinformatics at Milano-Bicocca) | 
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| * write runes (still have to learn ideograms...) | * write [http://en.wikipedia.org/wiki/Tengwar/ runes] (still have to learn ideograms...) | 
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| * throw snowballs (look out...) | 
Daniele Merico
Contact
Location: Common Lab Area, 6th Floor (CCBR)BR Email: MailTo(daniele DOT merico AT gmail DOT com)BR Skype: the-amerigoBR Linked-In: [http://www.linkedin.com/profile?viewProfile=&key=4048991&goback=%2Econ-*3conbro*40*4*051*4false*4*02*40%2Ebcc_2220874_1/ Daniele Merico]BR
Research Projects
Current Projects @CCBR:
- Active Cell Map (pathway & network: topology, expression profiling, activity patterns, etc...) - Supervised by: [:GaryBader:Gary Bader]. 
 
- With: [:RuthIsserlin:Ruth Isserlin]. Supervised by: [http://lambda.med.utoronto.ca/Emili.htm/ Andrew Emili] and [:GaryBader:Gary Bader]. 
 
Almost-completed or on-going Projects @UNIMI/UNIMIB:
- Knowledge Engineering of Human Phenotypes - With Gianluca Colombo. Supervised by: Giancarlo Mauri.
 
- Analysis of Time-course Microarray Data  - With Italo Zoppis. Supervised by: Marco Antoniotti.
 
- The p63 Network - With Alessandra Viganò. Supervised by: Roberto Mantovani. Ref & Links: [http://www.nature.com/emboj/journal/v25/n21/pdf/7601375a.pdf p63 EMBO Paper] 
 
- With Alessandra Viganò. Supervised by: Roberto Mantovani. 
Completed Projects @UNIMI/UNIMIB:
- Clinical Phenotype Ontology for Cerebrovascular Disorders (NEUROWEB Project) - With Gianluca Colombo, Flavio De Paoli, Marco Antoniotti. Supervised by: Giancarlo Mauri. Ref & Links: [http://www.nettab.org/2007/slides/SemanticWeb_Frisoni.pdf NETTAB 2007 presentation]; [http://nuke.neurowebkc.eu/Dissemination/tabid/66/Default.aspx/ published papers & proceedings]. 
 
- With Gianluca Colombo, Flavio De Paoli, Marco Antoniotti. Supervised by: Giancarlo Mauri. 
- The Landscape of NF-Y Binding - With: Michele Ceribelli, Diletta Dolfini. Supervised by: Roberto Mantovani. Ref & Links: (2 accepted papers) 
 
- With: Michele Ceribelli, Diletta Dolfini. Supervised by: Roberto Mantovani. 
Work Logs
[:DanieleMerico/WorkLogDirectory: Work logs] will be visible only to restricted lab personnel.
Knowledge Sharing
Here's the knowledge & expertise I wish to share with anybody who wants to.
Computational techniques & resources:
- PCA (Principal Correspondence Analysis) & CA (Correspondence Analysis) 
- Correlation Measures (Pearson, Spearman)
- Standard Affymetrix Microarray Analysis - (CEL files handling, Normalization, Signal computation (e.g. rma), Exploratory Analysis, Differentially Expressed Genes)
 
- Clustering (hirerarchical, K-means, CLICK, etc...)
- Statistical tests (t-test, Fisher's)
- Gene Ontology
I usually program with:
- [http://cran.r-project.org/ R] (see also [http://www.bioconductor.org/ Bioconductor]) 
Go to my [:DanieleMerico/HowtoDirectory: How To Directory] for tips with R programming.
Biological Systems and Pathologies I've been working on (in order of confidence):
- Mammalian Immune System (focus on Dendritic Cells)
- Ischemic Stroke & Atherosclerosis 
- Mammalian Chromatin Modification
- Yeast Cell Cycle
Resume & CV
I was born in Saronno (VA, Italy) in 29/07/1981. I lived, studied and worked in the Milan metropolitan area till November 2007. I got my BSc in Molecular Biotechnologies (July 2003) and my MSc Bioinformatics (July 2005) at Università di Milano-Bicocca. I started my PhD in Molecular and Cellular Biology at Università di Milano in 2005.BR My scientific interests are:
- Pathways and Networks
- Human Phenotypes
- Expression Data and Transcriptional Regulation
- Biomedical Knowledge Engineering & Representation 
- Philosophy and Sociology of Science
For more details, please have a look at my CV: [attachment:DanieleMericoCV.PDF CV.PDF].
Affiliations
- CCBR - Banting & Best Dept. of Medical Research - Visiting PhD student
 
- Università di Milano ([http://www.unimi.it UNIMI]) - Dipartimento di Scienze Biomolecolari e Biotecnologie ([http://www.sbb.unimi.it/ DSBB]) - PhD student (Program of Cellular and Molecular Biology)BR [http://www.bsb.unimi.it/gene_expression.htm Roberto Mantovani's Lab] 
 
- Università di Milano-Bicocca ([http://www.unimib.it UNIMIB]) - Dipartimento di Informatica ([http://www.disco.unimib.it/ DISCo]) - External PhD studentBR [http://bimib.disco.unimib.it/ BiMIB Group] (Bioinformatics at Milano-Bicocca) 
 
Trivia & Amenities
I like to...
- travel, and discover new cultures
- meet people
- discuss ideas
- take more than 45' to have lunch or dinner
- swim, walk, trek
- write [http://en.wikipedia.org/wiki/Tengwar/ runes] (still have to learn ideograms...) 
- drink beer
- throw snowballs (look out...)
- laugh   
