• ShirleyHui

Shirley Hui

Shirley is a Research Associate in the Bader Lab at the University of Toronto.

Email: <shirley.hui AT SPAMFREE utoronto DOT ca>

Supervisor: Gary Bader

Research Projects

• Current
  • RCC single cell genomics project

    • Weekly Update

• Past
  • Breast Cancer Pathway GSEA Project

    • PDF

  • Precision Medicine Projects

    • Progress Log

  • PDZ domain interaction prediction

    • Thesis: Computational Prediction of PDZ mediated Protein-Protein Interactions

      • Supervisory Committee: Charlie Boone, Quaid Morris, Tony Pawson

    • POW! Website: http://webservice.baderlab.org/domains/POW/

Education

• 2007 - 2013 University of Toronto - Ph.D. Department of Molecular Genetics

• 2002 - 2005 University of Waterloo - M.Math, focus on Computational Biology

• 1996 - 2001 University of Waterloo - B.Math, Honours Computer Science Co-op

Publications

• Association analysis identifies 65 new breast cancer risk loci, Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, et al.
  Nature (2017) Nov 2;551(7678):92-94. Epub 2017 Oct 23

• Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer, Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, et al.
  Nat Genet. (2017) Dec;49(12):1767-1778. Epub 2017 Oct 23

• Predicting PDZ domain mediated protein interactions from structure, Hui S, Xing X, Bader GD
  BMC Bioinformatics (2013) doi:10.1186/1471-2105-14-27 PubMed Abstract PDF

• Domain-mediated protein interaction prediction: From genome to network, Reimand J, Hui S, Jain S, Law B, Bader GD
  FEBS Lett. 2012 May 3PubMed Abstract PDF

• Proteome scanning to predict PDZ domain interactions using support vector machines, Hui S, Bader GD
  BMC Bioinformatics. 2010 Oct 12;11(1):50 PubMed Abstract PDF

• Rapid evolution of functional complexity in a domain family, Ernst A, Sazinsky SL, Hui S, Currell B, Dharsee M, Seshagiri S, Bader GD, Sidhu SS
  Science Signaling 2009 Sep 8;2(87):ra50 PubMed Abstract PDF

Work

• 2006
  • Toronto (Sunnybrook Hospital - Medical Imaging) - Research Analyst
• 2001 - 2006
  • Waterloo (AGFA Healthcare) - Software Development
• 1996 - 2001 (Co-op work terms - Software Development)
  • Ottawa (Corel)
  • Mississauga (Pervasive Software, Platform Computing)
  • San fransisco (Evolve Digital Consulting)

CategoryHomepage