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| Email: [[MailTo(shirleyh AT SPAMFREE gmail DOT com)]] | Shirley is a Research Associate in the Bader Lab at the University of Toronto in the Department of Molecular Genetics. |
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| Shirley is a graduate student in the Bader Lab at the University of Toronto in the Department of Molecular Genetics. * Supervisor: Gary Bader * Supervisory Committee: Tony Pawson, Quaid Morris, Charlie Boone |
'''Email''': <<MailTo(shirley.hui AT SPAMFREE utoronto DOT ca)>> |
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| == Research Project == * Computational prediction of protein domain-peptide interactions using machine learning methods. |
'''Supervisor''': Gary Bader |
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| == Current Interests == * Algorithms: Machine Learning - Support Vector Machines * Protein-protein interaction prediction |
== Research Projects == === Current === * [[/../MedicalDecisionMakingProject|Medical decision making]] * Progress [[/../MedicalDecisionMakingProject/Log| Log]] === Past === * [[/../DomainSpecificityPredictionProject|PDZ domain specificity prediction]] * Thesis: [[http://hdl.handle.net/1807/43599|Computational Prediction of PDZ mediated Protein-Protein Interactions]] * Supervisory Committee: [[http://www.utoronto.ca/boonelab/|Charlie Boone]], [[http://morrislab.med.utoronto.ca/|Quaid Morris]], [[http://pawsonlab.mshri.on.ca/|Tony Pawson]] ## * [wiki:/../DomainSpecificityPredictionProject/Log Progress] ##== Current Interests == ## * Algorithms: Machine Learning - Support Vector Machines ## * Peptide Recognition Domains: PDZ Domain |
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| * 1996 - 2001 University of Waterloo - B.Math Hons Computer Science Co-op * 2002 - 2005 University of Waterloo - M.Math focusing on applications in Bioinformatics |
* 2007 - 2013 [[http://www.utoronto.ca|University of Toronto]] - Ph.D. Department of Molecular Genetics * 2002 - 2005 [[http://www.cs.uwaterloo.ca/|University of Waterloo]] - M.Math focusing on applications in Bioinformatics * 1996 - 2001 [[http://www.cs.uwaterloo.ca/|University of Waterloo]] - B.Math Hons Computer Science Co-op |
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| == Skills == * Technical: * Programming Languages: Java, C++ * Numerical Analysis Software: Matlab * Non-Technical: * Play the Piano/Read Music (Gr 10 Royal Conservatory Hons) |
== Publications == |
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| == Things I Support == * Cancer Research and Related Fundraisers * [http://convio.cancer.ca/site/PageServer?pagename=RFL_ON_about_relay Canadian Cancer Society Relay For Life - Team Steven Hui] * Last year we raised $4030 * Earth Hour * [http://www.earthhour.org/] * WWF CN Tower Climb * [http://wwfcentral.ca/NetCommunity/Page.aspx?pid=503&srcid=500] * Sporting Life 10K - Easiest 10K! * [http://www.canadarunningseries.com/sportinglife/] |
* Predicting PDZ domain mediated protein interactions from structure, '''Hui S''', Xing X, Bader GD<<BR>>[[http://www.biomedcentral.com/1471-2105/14/27/abstract|BMC Bioinformatics (2013) doi:10.1186/1471-2105-14-27]] [[http://www.ncbi.nlm.nih.gov/pubmed/23336252|PubMed Abstract]] [[attachment:pdz-struct-2013.pdf|PDF]] |
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| == Things I Like (With Top 3 - or more - Recommends) == || Snowboarding || Snowbird, UT || Vail, CO || Whistler/Blackcomb, BC || || Leisure reading || The Time Traveler's Wife, Niffeneger || Kite Runner, Hosseini || The Curious Incident of The Dog in The Night Time, Haddon || || Traveling || Munich, Germany || Guilin, China || Rockies, BC || || Camping/Hiking || West Coast Trail, BC (Challenging!!!) || Moab, UT *haven't been but want to go || Algonquin Park, ON || || Natural Wonders || Rockies, BC || Grand Canyon, CO || Athabasca Glacier, BC || || || Ben Nevis, UK || Guilin Landscape, China || Owen's Point, BC || || || Mt. St. Helen, WA || Badlands, AB || ... || || Man Made "Wonders" || Great Wall, China || Neuschwanstein, Germany || Edinburgh Castle, UK || || Favourite Foods || Sushi || Seafood (crab, lobster) || Veggies || || Places I Want to Travel to || Japan || Australia || Spain/Egypt/Morocco || || Favourite Coffee || Guatemala, Starbucks || Belgium Chocolate, Second Cup || || |
* Domain-mediated protein interaction prediction: From genome to network, Reimand J, '''Hui S''', Jain S, Law B, Bader GD<<BR>> [[http://www.sciencedirect.com/science/article/pii/S001457931200316X|FEBS Lett. 2012 May 3]][[http://www.ncbi.nlm.nih.gov/pubmed/22561014|PubMed Abstract]] [[attachment:Genome2NetworkReview.pdf|PDF]] |
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| == Places I Have Worked == | * Proteome scanning to predict PDZ domain interactions using support vector machines, '''Hui S''', Bader GD<<BR>> [[http://www.biomedcentral.com/1471-2105/11/507|BMC Bioinformatics. 2010 Oct 12;11(1):50]] [[http://www.ncbi.nlm.nih.gov/pubmed/20939902|PubMed Abstract]] [[attachment:2010_HuiBader-ProteomeScanningPDZ_BMCBioinformatics.pdf|PDF]] * Rapid evolution of functional complexity in a domain family, Ernst A, Sazinsky SL, '''Hui S''', Currell B, Dharsee M, Seshagiri S, Bader GD, Sidhu SS<<BR>> [[http://stke.sciencemag.org/cgi/content/full/sigtrans;2/87/ra50|Science Signaling 2009 Sep 8;2(87):ra50]] [[http://www.ncbi.nlm.nih.gov/pubmed/19738200|PubMed Abstract]] [[attachment:2009_Ernst_PDZEvolution_ScienceSignaling_Sep.pdf|PDF]] == Work == |
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| * Ottawa (Corel) * Mississauga (Pervasive Software, Platform Computing) * San fransisco (Evolve Digital Consulting) |
* Ottawa (Corel) * Mississauga (Pervasive Software, Platform Computing) * San fransisco (Evolve Digital Consulting) |
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| * Waterloo (AGFA Healthcare) - Software Development | * Waterloo (AGFA Healthcare) - Software Development |
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| * Toronto (Sunnybrook Hospital - Medical Imaging) - Research Analyst | * Toronto (Sunnybrook Hospital - Medical Imaging) - Research Analyst ## == Skills == ## * Technical: ## * Programming Languages: Java ## * Numerical Analysis Software: Matlab, R ## * Non-Technical: ## * Piano/Read Music (Gr 10 [[http://www.rcmusic.ca/html|Toronto Royal Conservatory]]) ## == Things I Support == ## * [[http://convio.cancer.ca/site/PageServer?pagename=RFL_ON_about_relay|Canadian Cancer Society Relay For Life - Team Steven Hui]] ## * [[http://www.ottawanrf.com/2007/our_kids.htm|Ottawa Neuroblastoma Fund]] ## * [[http://www.earthhour.org/|Earth Hour]] ## * [[http://wwfcentral.ca/NetCommunity/Page.aspx?pid=503&srcid=500|WWF CN Tower Climb]] ## * [[http://www.canadarunningseries.com/sportinglife/|Sporting Life 10K - Easiest 10K!]] ## == Places I Have Worked == |
Shirley Hui
Shirley is a Research Associate in the Bader Lab at the University of Toronto in the Department of Molecular Genetics.
Email: <shirley.hui AT SPAMFREE utoronto DOT ca>
Supervisor: Gary Bader
Research Projects
Current
Progress Log
Past
PDZ domain specificity prediction
Thesis: Computational Prediction of PDZ mediated Protein-Protein Interactions
Supervisory Committee: Charlie Boone, Quaid Morris, Tony Pawson
Education
2007 - 2013 University of Toronto - Ph.D. Department of Molecular Genetics
2002 - 2005 University of Waterloo - M.Math focusing on applications in Bioinformatics
1996 - 2001 University of Waterloo - B.Math Hons Computer Science Co-op
Publications
Predicting PDZ domain mediated protein interactions from structure, Hui S, Xing X, Bader GD
BMC Bioinformatics (2013) doi:10.1186/1471-2105-14-27 PubMed Abstract PDFDomain-mediated protein interaction prediction: From genome to network, Reimand J, Hui S, Jain S, Law B, Bader GD
FEBS Lett. 2012 May 3PubMed Abstract PDFProteome scanning to predict PDZ domain interactions using support vector machines, Hui S, Bader GD
BMC Bioinformatics. 2010 Oct 12;11(1):50 PubMed Abstract PDFRapid evolution of functional complexity in a domain family, Ernst A, Sazinsky SL, Hui S, Currell B, Dharsee M, Seshagiri S, Bader GD, Sidhu SS
Science Signaling 2009 Sep 8;2(87):ra50 PubMed Abstract PDF
Work
- 1996 - 2001 (Co-op work terms - Software Development)
- Ottawa (Corel)
- Mississauga (Pervasive Software, Platform Computing)
- San fransisco (Evolve Digital Consulting)
- 2001 - 2006
- Waterloo (AGFA Healthcare) - Software Development
- 2006
- Toronto (Sunnybrook Hospital - Medical Imaging) - Research Analyst